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701 - 750 of 1458 citations for 7 Amino 1 3 dimethyl 1H 8H pyrido 2 3 d pyrimidine 2 4 5 trione since 2020

• Single cell spatial analysis identifies regulators of brain tumor initiating cells

  Reza Mirzaei, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Tissues were then incubated overnight at 4°C with following antibodies resuspended in antibody dilution buffer (PBS, 1% BSA, 0.1% cold fish stain gelation, and 0.1% Triton X-100): biglycan (1:500; Novus Biologicals, NBP1-84971), SOX2 (1:200 ...
• Pioneer factor GAF cooperates with PBAP and NURF to regulate transcription

  Julius Judd, Fabiana M. Duarte, John T. Lis, bioRxiv - Genomics 2020

  Quote: Western blots were performed using anti-GAF (lab-made, 1:500) or anti-NURF301(Novus Biologicals Cat. No. 40360002; 1:100), with anti-Chromator (lab-made ...
• Human Abdominal Subcutaneous-Derived Active Beige Adipocytes Carrying FTO rs1421085 Obesity-Risk Alleles Exert Lower Thermogenic Capacity

  Attila Vámos, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary antibody incubations were kept overnight with anti-TOM20 (1:75, WH0009804M1) and anti-LC3 (1:200, Novus Biologicals, NB100-2220). Secondary antibody incubation was for 3 h with Alexa Fluor 647 goat anti-mouse IgG (1:1000 ...
• Transcriptome network analysis link perinatal Staphylococcus epidermidis infection to microglia reprogramming in the immature hippocampus

  Giacomo Gravina, et al., bioRxiv - Neuroscience 2022

  Quote: Caspase-1 activity from hippocampal lysates was analysed by enzyme-linked immunosorbent assay (ELISA) kit and standard (Mouse caspase-1, Novus Biologicals, Littleton ...
• MyD88-Dependent Signaling Drives Toll-Like Receptor-Induced Trained Immunity in Macrophages

  Allison M. Owen, et al., bioRxiv - Immunology 2022

  Quote: ... The slides were incubated for 1 hour with anti-F4/80 primary antibody (1:900 dilution; NB600-404 Novus Biologicals LLC), followed by 15minute secondary antibody incubation (1:7500 dilution ...
• Disease-Associated Non-Coding Variants Alter NKX2-5 DNA-Binding Affinity

  Edwin G. Peña-Martínez, et al., bioRxiv - Biochemistry 2022

  Quote: ... Membranes were blocked using 5% milk in TBST buffer for 1 h in orbital shaking and incubated overnight with 1:10,000 dilution of Anti-His mouse monoclonal antibodies (Novus Biologicals, AD1.1.10). The SDS-PAGE and Western Blot Analysis results were imaged using Azure® Biosystems Imager.
• Characterization of 3D organotypic epithelial tissues reveals tonsil-specific differences in tonic interferon signaling

  Robert Jackson, et al., bioRxiv - Cell Biology 2023

  Quote: ... HPA043673-100UL) and anti-CRNN upper epithelial marker (goat polyclonal, 1:200, 1 µg/mL, Novus Biologicals, Catalog No. 103242-512). Following PBS washes ...
• Cardiovascular Disease-Associated Non-Coding Variants Disrupt GATA4-DNA Binding and Regulatory Functions

  Edwin G. Peña-Martínez, et al., bioRxiv - Genomics 2024

  Quote: ... Membranes were blocked using 5 % milk in 1× TBST buffer for 1 h in orbital shaking and incubated overnight with 1:10,000 dilution of Anti-His mouse monoclonal antibody (Novus Biologicals, AD1.1.10). The SDS-PAGE and Western Blot Analysis results were imaged using Azure Sapphire Bio-molecular Imager (Azure Biosystems ...
• Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation

  Rachel Ulferts, et al., bioRxiv - Cell Biology 2020

  Quote: Antibodies used in this study are anti-LC3B (NB100-2220 and NBP2-46892, Novus Biologicals, WB 1:1000 and 1: 2000 respectively), anti-Influenza A Virus M2 Protein antibody [14C2] (ab5416 ...
• Role of autophagy in sepsis-induced skeletal muscle dysfunction, whole-body metabolism, and survival

  Jean-Philippe Leduc-Gaudet, et al., bioRxiv - Cell Biology 2021

  Quote: ... muscle sections were incubated for 1 hour at room temperature with anti-mouse p62/SQSTM1 (Novus Biologicals Inc. clone 2C11, 1:200). Sections were then washed three times in PBS before being incubated for 1 h at room temperature with an Alexa Fluor® 488 goat anti-rabbit IgG antibody (A-21131 ...
• Arc ubiquitination regulates endoplasmic reticulum-mediated Ca²⁺ release and CaMKII signaling

  Mohammad A. Ghane, et al., bioRxiv - Neuroscience 2022

  Quote: ... overnight at 4°C and then incubated with primary antibodies (Arc, Synaptic Systems #156003, 1:1000; CaMKII, Abcam #ab52476, 1:1000; CaMKII p-Thr286 p-Thr287 Novus Biologicals #NB110-96896 ...
• Nucleus translocation of tRNA synthetase mediates late integrated stress response

  Na Wei, et al., bioRxiv - Molecular Biology 2020

  Quote: ... rabbit polyclonal p66a (1:1000, NOVUS BIOLOGICALS, NB100-56643), rabbit polyclonal LSD1 (1:1000 ...
• Aryl Hydrocarbon Receptor Blocks Aging-Induced Senescence in the Liver and Fibroblast Cells

  Ana Nacarino-Palma, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Specific primary antibodies anti-p16Ink4a (Novus Biologicals 1:200), anti-p21Cip1 (Santa Cruz Biotechnology 1:100 ...
• Coordination of RNA and protein condensation by the P granule protein MEG-3

  Helen Schmidt, et al., bioRxiv - Cell Biology 2020

  Quote: ... Rat αOLLAS-L2 (1:200, Novus Biological Littleton, CO), Secondary antibodies were applied for 2 hr at room temperature ...
• Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts

  Ramona Jühlen, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-rapsyn (1:200; NBP1-85537; Novus Biologicals), rabbit anti-MuSK (1:100 ...
• “TMEM16K is an interorganelle regulator of endosomal sorting”

  Maja Petkovic, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-TGN38 (Novus Biologicals, #NBP1-03495SS, 1/100), and mouse anti-VAPB (R&D systems ...
• “TMEM16K is an interorganelle regulator of endosomal sorting”

  Maja Petkovic, et al., bioRxiv - Cell Biology 2020

  Quote: ... chicken anti-mCherry (Novus Biologicals, #NBP2-25158, 1/200) mouse anti-EEA1 (BD Biosciences ...
• Critical role for cold shock protein YB-1 in cytokinesis

  Sunali Mehta, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Moesin (MSN/491, Novus biologicals, 1:200). Secondaries used were goat anti-rabbit Alexa Fluor 488 (Molecular Probes ...
• Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins

  Yulia Steblyanko, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-KIF2A (1:1000; Novus Biologicals, NB500-180); rabbit anti-KIF4A (1:1000 ...
• K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15

  Marcus A Begley, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-NuMA (1:400, Novus Biologicals NB500-174SS), human anti-centromere protein (CREST ...
• In situ architecture of neuronal α-Synuclein inclusions

  Victoria A. Trinkaus, et al., bioRxiv - Cell Biology 2020

  Quote: ... MAP2 (NB300-213, Novus Biologicals; 1:500; RRID: AB_2138178), p62 (ab56416 ...
• Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts

  Lara-Jane Kepser, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-actin (1:5,000, #NB600-535, Novus Biologicals), mouse anti-GAPDH (1:10,000 ...
• Genome-Wide CRISPR Screen Identifies Non-Canonical NF-κB Signaling as a Potent Regulator of Density-dependent Proliferation

  Maria Fomicheva, Ian G. Macara, bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-YAP (1:200, Novus Biologicals, NB110-58358), rabbit phospho-RB Ser807/811 (1:1000 ...
• Unexpected opposing biological effect of genetic risk factors for Parkinson’s disease

  Marcus Keatinge, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse LAMP1 antibody (Novus Biologicals NPB2-25155, 1:8000). Human α-synuclein in cell culture media was detected using LEGEND MAX ELISA kit (BioLegend) ...
• Aβ toxicity rescued by protein retention in the ER

  James H Catterson, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-BiP (1:1000; Novus Biologicals #NBP1-06274), rabbit anti-Actin (1:5,000 ...
• Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites

  Alana Sherker, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-RAP80 Rabbit (NBP1-87156, Novus Biologicals, 1:500) anti-ABRAXAS (A302- 180A ...
• Temporal analysis of enhancers during mouse brain development reveals dynamic regulatory function and identifies novel regulators of cerebellar development

  Miguel Ramirez, et al., bioRxiv - Neuroscience 2021

  Quote: ... rabbit anti-Foxp2 (1:2000, Novus Biologicals NB100-55411), chicken anti-Doublecortin ...
• IP6K1 upregulates the formation of processing bodies by promoting proteome remodeling on the mRNA cap

  Akruti Shah, Rashna Bhandari, bioRxiv - Cell Biology 2020

  Quote: ... anti-eIF4A2 (Novus Biologicals, NBP2-24529; IB 1:1000). Restriction enzymes were purchased from New England Biolabs ...
• A Novel Organoid Model of In Vitro Spermatogenesis Using Human Induced Pluripotent Stem Cells

  Meghan Robinson, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 1:300 anti-SYCP3 (Novus Biologicals, NB300-232). Sections were incubated in the diluted primary antibodies overnight in a humidity chamber at room temperature ...
• mRNA-decapping associated DcpS enzyme controls critical steps of neuronal development

  Iva Salamon, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-Brn1 (Novus Biologicals, 1:600, NBP1-49872), goat anti-Tle4 (SCB ...
• A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites

  S. Elizarova, et al., bioRxiv - Neuroscience 2021

  Quote: ... chicken anti-MAP2 (1:2000, Novus Biologicals, NB300-213), mouse anti-GFP (1:1000 ...
• A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses

  Huan Du, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-AIF-1/Iba1 (Novus Biologicals, NB100-1028), rat anti-CD68 (Bio-Rad ...
• BMP7 increases UCP1-dependent and independent thermogenesis with a unique gene expression program in human neck area derived adipocytes

  Abhirup Shaw, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-ID1 (1:1000, Novus Biologicals, JM92-13). HRP-conjugated goat anti-rabbit (1:10,000 ...
• Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A is Mediated by Replication Protein A in Ovarian Cancer

  Shruthi Sriramkumar, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-Rad51 (Novus biological, CO NB100-148, 1:100), anti-H2AK119ub1 (Millipore Sigma ...
• TET1-mediated DNA hydroxy-methylation regulates adult remyelination

  Sarah Moyon, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-TET1 (Novus Biologicals, NBP1-78966, 1:100), rabbit anti-TET2 (Epigentek ...
• Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation

  Tina A. Solvik, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-CYC1 (Novus Biologicals, NBP1-86872; 1:1,000), mouse anti-NUP62 (BD Biosciences ...
• Crossover patterning through kinase-regulated condensation and coarsening of recombination nodules

  Liangyu Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rabbit anti-RAD-51 (1:5,000, Novus Biologicals, #29480002), Goat anti-SYP-1 [1:300 ...
• Specific telomere protection ensured by FOXO3a upon genotoxic stress and during aging

  Maria Sol Jacome Burbano, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit polyclonal (NB 100-305, 1:200, Novus Biologicals) and 8-Oxoguanine ...
• Extracellular Matrix Dysfunction in Sorsby Patient-Derived Retinal Pigment Epithelium

  Abbi L. Engel, et al., bioRxiv - Cell Biology 2021

  Quote: ... TIMP2 (1:500, H00007077-M03J, Novus Biologicals, Centennial, CO), TIMP3 (1:5000 ...
• A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes

  Gina M. Borgo, et al., bioRxiv - Microbiology 2021

  Quote: ... mouse anti-NDP52 (1:300; Novus Biologicals, H00010241-B01P). For staining with rabbit polyclonal anti-LC3 (1:250 ...
• Tau conformers in FTLD-MAPT undergo liquid-liquid phase separation and perturb the nuclear envelope

  Sang-Gyun Kang, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-NUP98 pAb (1:2,000, NBP1-58188, Novus Biologicals); anti-Lamin B1 pAb (1:2,000 ...
• SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice

  Alan T. Tang, et al., bioRxiv - Microbiology 2021

  Quote: ... DC-LAMP (rat, 1:25, Novus Biologicals, DDX0191P-100), ICAM-1 (rabbit ...
• The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

  Feng Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-Gap43 (NB300-143, 1:1000, Novus Biologicals), rabbit anti-SCG10 (NBP1-49461 ...
• Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in tuberous sclerosis complex and Alzheimer’s disease

  Farr Niere, et al., bioRxiv - Neuroscience 2021

  Quote: ... we used: mouse anti-DJ1 (1:2000; Novus Biologicals), mouse anti-tubulin (1:20,000 ...
• Relationship Between Neuroendocrine and Immune Gene Expression in Small Cell Lung Cancer

  Ling Cai, et al., bioRxiv - Cancer Biology 2020

  Quote: ... POU2F3 (dilution 1:200; polyclonal, Novus Biologicals, NBP1-83966), CD4 (dilution 1:80 ...
• A non-canonical lipid droplet metabolism regulates the conversion of alpha-Synuclein to proteolytic resistant forms in neurons of a Drosophila model of Parkinson disease

  Victor Girard, et al., bioRxiv - Cell Biology 2021

  Quote: ... and rabbit anti-PLIN3 (1:500, NB110, Novus Biologicals) antibodies diluted in PBS containing 5% BSA and 0.05% saponin ...
• A non-canonical lipid droplet metabolism regulates the conversion of alpha-Synuclein to proteolytic resistant forms in neurons of a Drosophila model of Parkinson disease

  Victor Girard, et al., bioRxiv - Cell Biology 2021

  Quote: ... and rabbit anti-PLIN3 (1:500, NB110, Novus Biologicals) primary antibodies at room temperature for 1 h ...
• The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

  Feng Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-SCG10 (NBP1-49461, 1:5000, Novus Biologicals), DAPI (D9542 ...
• Analysis of meiosis in Pristionchus pacificus reveals plasticity in homolog pairing and synapsis in the nematode lineage

  Regina Rillo-Bohn, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat anti-HA (1:500, Novus Biologicals #NB600-362), and mouse anti α-tubulin ...
• Opposing motors provide mechanical and functional robustness in the human spindle

  Lila Neahring, Nathan H. Cho, Sophie Dumont, bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-NuMA (1:1,000, NB500-174, Novus Biologicals), rabbit anti-Kif15 (1:500 ...