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Citations for Bachem :
51 - 100 of 176 citations for 6H Imidazo 4 5 h quinolin 6 one 1 9 dihydro 9CI since 2019
Citations are collected from bioRxiv only, the total number of publications could be much larger.
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bioRxiv - Cell Biology 2022Quote: ... Neonatal C57BL/6 mice (3 days after birth) were injected ip with NaCl or BNP every two days (1µg/2g; Bachem; synthetic mouse BNP (1-45) peptide (catalog number H-7558)) ...
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bioRxiv - Biochemistry 2020Quote: ... and H-Glu(Thz-Gly-OH)-OH trifluoroacetate) were synthesized by Bachem (UK) Ltd ...
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bioRxiv - Biophysics 2020Quote: ... and 10 mM of phenylalanine peptide (H-Phe-Phe-Phe-OH) (Bachem, CA) were mixed into solutions without ants ...
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bioRxiv - Pathology 2021Quote: ... murine AngII (mAngII, 1,000 ng/kg/min, Cat # H-1705, Bachem, Torrance, CA), or bovine AngII (bAngII ...
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bioRxiv - Animal Behavior and Cognition 2022Quote: Male C57Bl/6J mice were treated with cerulein (Bachem H-3220.0005, Bubendorf, Switzerland) to induce chronic pancreatitis ...
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bioRxiv - Physiology 2021Quote: PRP was diluted in phosphate buffered saline (PBS; 1:40) and incubated with protease-activated receptor-4 activating peptide AYPGKF amide (PAR4-amide, 200 μM; Bachem) or PBS for 20 min at 37°C in presence of anti-CD62P-BV421 (clone RB40.34 ...
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bioRxiv - Biophysics 2021Quote: ... The top fraction reached a concentration of 1 mg/mL and 3.6 µL supplemented with 5 mM of the dipeptide Alanine-Phenylalanine (Bachem) was applied to glow discharged gold holey carbon 2/1 300-mesh grids (Quantifoil) ...
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bioRxiv - Microbiology 2022Quote: ... One unit of activity corresponds to the number of micromoles of Z-Arg-Arg-pNA (BACHEM) digested per min per mg of protein.
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bioRxiv - Biochemistry 2020Quote: ... 0.5 mM pBPA (H-p-Bz-Phe-OH F-2800; Bachem AG, Bubendorf, Switzerland), and 0.02% arabinose until early log phase ...
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bioRxiv - Synthetic Biology 2022Quote: ... H-p-Chloro-DL-Phe-OH (p-Cl-Phe) was purchased from Bachem (Switzerland).
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bioRxiv - Physiology 2023Quote: ... Cells were serum starved prior to incubation with GIP (100 nM, H-3824.0500, Bachem) for the indicated times.
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bioRxiv - Cell Biology 2019Quote: ... 1 μg lysate was incubated with 100 μM Z-Gly-Pro-Arg-7-(4-methyl)-coumarylamide (MCA) (Bachem, St Helens, UK), a specific substrate for cathepsin K ...
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bioRxiv - Cell Biology 2020Quote: ... After 16h beads were washed 5 times with IP buffer and eluted twice with 250 ul of 1 mg/ml 3x-FLAG peptide (Bachem) in TBS pH 7.5 and eluates were pooled.
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bioRxiv - Neuroscience 2023Quote: ... or CCK (5 μg/kg) (BACHEM). Behavioral tests were usually performed 20-30 min after drug injection ...
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bioRxiv - Immunology 2020Quote: In vitro aggregation of amyloid peptide (Aβ1-42, Bachem #H-1368, 100 μM in PBS) was carried out by incubation for 4 days at 37°C ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: ... Atrial natriuretic peptide receptor antagonist (A71915, 50µg/Kg BW/day, H-3048, Bachem California, Torrance, CA) was dissolved in saline and delivered via minipumps in mice during HSD feeding period ...
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bioRxiv - Neuroscience 2021Quote: OXT (0.3 IU/5 μL; Bachem, Switzerland) was administered intranasally ...
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bioRxiv - Neuroscience 2022Quote: ... at baseline and during perfusion of the high affinity GLP-1R agonist Exendin-4 (Ex-4; 100nM; catalog #4044219, Bachem, Torrance, CA). The baseline I–V was subtracted from the I–V during Ex-4 to determine the reversal potential of the Ex-4-mediated current ...
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bioRxiv - Biophysics 2022Quote: ... 4 mg of BzF (MW: 269.3; Bachem, Bubendorf, Switzerland) were dissolved in 300 μL of HCl (1M) ...
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bioRxiv - Pharmacology and Toxicology 2024Quote: ... Amino-4-methylcoumarin (Ala–AMC) was purchased from Bachem. Briefly ...
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bioRxiv - Pathology 2020Quote: ... mice were infused with 1,000 ng/kg/min of AngII (Cat # H-1705; Bachem, Torrance, CA, USA) subcutaneously via Alzet mini osmotic pumps (Alzet Model # 2006 ...
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bioRxiv - Cancer Biology 2020Quote: ... and 500 µM mouse PAR-4-amide (Bachem, Torrance, CA) at 37°C for 45 minutes to stimulate release of granular contents.
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bioRxiv - Immunology 2021Quote: PADRE peptide (AKFVAAWTLKAAA) and the immunodominant class I peptide of C57BL/6 mice (SIINFEKL) were synthesized by Bachem AG (Bubendorf ...
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bioRxiv - Biochemistry 2022Quote: ... All assays were performed with 75 ng enzyme on 96-well plates (BIOFIL®) in purification butter supplemented with 0.3 mM h-Gly-Pro-βNA (BaChem) at 30 °C ...
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bioRxiv - Cell Biology 2023Quote: ... sterile membrane damage was induced with 5 mM LLOMe (Bachem) as described in (6) ...
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bioRxiv - Microbiology 2022Quote: ... discoideum was induced using 4.5–5 mM of LLOMe (Bachem) from a 10-fold concentrated solution that was added 5 min after the start of imaging ...
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bioRxiv - Neuroscience 2024Quote: ... the formalin test was carried out after intracisternal administration of OT (0.25 or 1.0 µg in 10 µl of saline; H-2510, Bachem Holding AG, Bubendorf, Switzerland) or saline [56] ...
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bioRxiv - Pharmacology and Toxicology 2020Quote: Z-RLRGG-7-amino-4-methyl-courmarin (peptide-AMC) was purchased from Bachem. Ubiquitin−7-amino-4-methylcourmarin (Ub-AMC ...
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bioRxiv - Biochemistry 2022Quote: Hydrolysis of the fluorogenic-peptide substrates suc-LLVY-AMC (7-amino-4-methylcoumarin; Bachem) was quantified to determine the proteolytic activity of proteasomes ...
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bioRxiv - Microbiology 2022Quote: ... which was synthesized by incorporating Fmoc-beta-(7- methoxycoumarin-4-yl)-Ala-OH (Mca, Bachem) at position 10 and Fmoc-Cys(Trt)-OH (Novabiochem ...
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bioRxiv - Biochemistry 2022Quote: ... Thrombin substrate benzyloxycarbonyl-glycyl-glycyl-arginine 7-amido-4-methylcoumarin (ZGGR-AMC) was purchased from Bachem AG ...
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bioRxiv - Neuroscience 2019Quote: ... N-succinyl-Leu-Leu-Val-Tyr-7-amino-4-methylcoumarin (Suc-LLVY-AMC) substrate was used (BACHEM). GST-Ubl and His-UIM constructs were a gift from the Alfred Goldberg lab ...
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bioRxiv - Cell Biology 2022Quote: ... TA substrates were generated that contained the unnatural amino acid and photocrosslinker 4-Benzoylphenylalanine (BpA) (Bachem, Switzerland), which was incorporated into the TMD by amber stop codon suppression in the PURExpress system lacking all release factors (ΔRF123 ...
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bioRxiv - Neuroscience 2024Quote: ... native amino acids at the following CpxII positions were replaced by 4-Benzoyl-L-Phenylalanin (BPA Bachem) as described by Malsam et al. ...
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bioRxiv - Neuroscience 2019Quote: ... 0.5 µM glutamine and penicillin/streptomycin (supplemented NB) and either with 4 mM L-azidohomoalanine (L-AHA) (Bachem) or 4 mM L-Methionine (Sigma-Aldrich ...
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bioRxiv - Neuroscience 2021Quote: ... glucagon-like peptide 1 (GLP-1; 1µM, Bachem), 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX ...
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Activation of innate immune cGAS-STING pathway contributes to Alzheimer’s pathogenesis in 5×FAD micebioRxiv - Neuroscience 2022Quote: ... The conditioned medium from the primary activated microglia (MCM) treated with 5 μM oligomeric Aβ (4090148.1000, Bachem) were collected and added to primary astrocytic cultures for 24 h ...
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bioRxiv - Neuroscience 2021Quote: ... and glucagon-like peptide 1 (GLP-1; 1µM, Bachem) were stocked at 100× concentration at -20°C and were freshly diluted in the recording ACSF prior the application by bath perfusion.
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bioRxiv - Molecular Biology 2020Quote: Synthetic unlabeled Aβ(1-42) (Bachem AG, 1 mg aliquot) was incubated with 700 μl hexafluoro-2-propanol (HFIP ...
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bioRxiv - Immunology 2021Quote: ... and incubated with the thrombin substrate Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride (0.42 mM) (Bachem AG, Switzerland) and CaCl2 (15 mM ...
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Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptorbioRxiv - Biochemistry 2021Quote: Enzymatic activity of ACE2 was determined and quantified as described previously,37 using 100 μM 7-methoxycoumarin-4-yl-acetyl-Ala-Pro-Lys-2,4-dinitrophenyl (Bachem, Switzerland) as substrate.
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bioRxiv - Neuroscience 2022Quote: ... bilaterally delivered sterile saline (catalog #07-892-4348, Patterson Veterinary, Devens, MA) or Exenatide acetate (Ex-4; catalog #4044219, Bachem) in 0.25µl volume ...
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bioRxiv - Biochemistry 2021Quote: ... Plasma was incubated with the thrombin substrate Z-Gly-Gly-Arg 7-amido-4-methylcoumarin hydrochloride (0.42 mM) (Bachem AG, Switzerland) and CaCl2 (15 mM ...
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bioRxiv - Cell Biology 2020Quote: ... RIPK2 knock-out and FLAG-RIPK2 knock-in (hetero- and homozygous) mice were administered MDP (5 mg/kg, i.p. in 200 μL PBS, Bachem) or PBS and sacrificed after 4 hours ...
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bioRxiv - Biochemistry 2022Quote: ... endothelin-1 (Bachem, H6995.0001), isoproterenol (Sigma Aldrich ...
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bioRxiv - Systems Biology 2021Quote: ... were prepared by mixing 8-arm 40 kDa PEG-Nb with 5 kDa PEG-dithiol crosslinker (JenKem) and 2 mM CRGDS cell adhesive peptide (Bachem) at a 0.99:1 thiol-to-ene ratio in phosphate buffered saline (PBS ...
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bioRxiv - Cell Biology 2020Quote: ... The chymotrypsin-like activity of the proteasome was detected by incubating the gel in overlay buffer (20 mM Tris, 5 mM MgCl2) containing 100 μM Suc-LLVY-AMC (Bachem) for 30 min at 37°C ...
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bioRxiv - Physiology 2021Quote: ... Half of the mice also received a 1,000-fold excess (5 nmol) of non-radioactive glucagon in combination with 125I-Glucagon (Bachem, Switzerland) in the same injection to test for specific binding ...
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bioRxiv - Biophysics 2021Quote: ... 1 mM EDTA and 1 % (w/v) n-octyl polyoxyethylene (Octyl-POE, Bachem, Switzerland). The purity of the protein was assessed by SDS-PAGE.
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bioRxiv - Neuroscience 2020Quote: ... 1 μM OT (Bachem, Switzerland) or 10 μM all-trans retinoic acid -ATRA (Sigma-Aldrich ...