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251 - 300 of 2165 citations for 7 METHYLTHIENO 2 3 B QUINOLINE 2 CARBOXYLIC ACID since 2019

• Expansion of Ventral Foregut Primes the Enhancer Landscape for Organ Specific Differentiation

  Yan Fung Wong, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and 2 µg of H3K27ac (Abcam, ab4279). Immunoprecipitation and washes were done as described in the True MicroChIP protocol ...
• Mer3 helicase protects early crossover intermediates from STR complex disassembly during meiosis

  Veronika Altmannova, et al., bioRxiv - Biochemistry 2022

  Quote: ... Anti-Strep antibody (2 μL, Abcam, ab76949) was added to the reactions and the mixtures were incubated for 1 hour at 4°C in the thermomixer (950 rpm) ...
• Endogenous Rab38 regulates LRRK2’s membrane recruitment and substrate Rab phosphorylation in melanocytes

  Alexandra Unapanta, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-LRRK2 C41-2 (Abcam, ab133474), rabbit anti-LRRK2 phospho S1292 (Abcam ...
• The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity

  Sinem Yılmaz, et al., bioRxiv - Cell Biology 2022

  Quote: ... Antibodies against Nrf-2 (Abcam, Ab-62352), Nrf-2 (Bioss ...
• Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells

  R. Chittajallu, et al., bioRxiv - Neuroscience 2020

  Quote: ... 2-5μM CGP556845A (Abcam; Cat. No. ab120337), 5-10μM bicuculline methobromide (Abcam ...
• A noble TGFβ biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

  Han-Soo Kim, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... or 1:500 anti- MD-2 (Abcam) antibodies and 1:200 FITC conjugated secondary antibody (Young In Frontier ...
• EZH2 Abundance Regulated by UHRF1/UBE2L6/UBR4 Ubiquitin System is the Potential Therapeutic Target to Trigger Pigmented Phenotype in Melanoma

  Gamze Kuser Abali, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MG132 and 5’-Aza-2’-deoxycytidine (Abcam); cycloheximide and DZNep (Sigma ...
• The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing

  A.D. Podgurskaya, et al., bioRxiv - Biophysics 2019

  Quote: ... β-myosin light chain 2 (Abcam, ab79935) 1:100 ...
• Biological Plasticity Rescues Target Activity in CRISPR Knockouts

  Arne H. Smits, et al., bioRxiv - Bioengineering 2019

  Quote: ... Antibody 2: Rabbit anti-BRD4 (Abcam #ab128874). 100 µl AminoLink resin (Thermo Fisher Scientific ...
• SARS-CoV-2 infects cells following viral entry via clathrin-mediated endocytosis

  Armin Bayati, et al., bioRxiv - Cell Biology 2020

  Quote: ... or Pitstop 2 (15 μM; Abcam, ab120687) in serum free media for 30 or 20 min ...
• Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus

  Vikram Gopal, et al., bioRxiv - Microbiology 2021

  Quote: ... and SARS-CoV-2 S (Abcam ab272504) and N (GeneTex ...
• The sequential and cooperative action of CSB, CSA and UVSSA targets the TFIIH complex to DNA damage-stalled RNA polymerase II

  Yana van der Weegen, et al., bioRxiv - Molecular Biology 2019

  Quote: ... and 2 µg RNAPII-S2 (ab5095, Abcam) for 2-3 h at 4 °C ...
• MACF1 Facilitates SMAD7 Nuclear Translocation to Drive Bone Formation in Mice

  Fan Zhao, et al., bioRxiv - Developmental Biology 2019

  Quote: ... or 2 µg Rabbit IgG (Abcam, ab46540). The antigen/antibody complexes were then mixed with 40 µL recombinant Protein A+G agarose beads (Beyotime ...
• Vinculin anchors contractile actin to the cardiomyocyte adherens junction

  Chelsea D. Merkel, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-Desmoglein 2 (1:250, Abcam EPR6768), anti-α-Actinin (1:250 ...
• Chromatin landscape dynamics in development of the plant parasitic nematode Meloidogyne incognita

  Rahim Hassanaly-Goulamhoussen, et al., bioRxiv - Genomics 2021

  Quote: ... H3K9me3 (Abcam ref ab8898, batch GR306402-2), H3K27ac (Abcam ref ab4729 ...
• Chromatin landscape dynamics in development of the plant parasitic nematode Meloidogyne incognita

  Rahim Hassanaly-Goulamhoussen, et al., bioRxiv - Genomics 2021

  Quote: ... H3K27ac (Abcam ref ab4729, batch GR150367-2), H3K27me3 (Epigentek ref A-4039 ...
• Human HMGN1 and HMGN2 are not required for transcription-coupled DNA repair

  Katja Apelt, et al., bioRxiv - Cell Biology 2019

  Quote: ... and 2 µg RNAPII-S2 (ab5095, Abcam) for 1 h at 4 °C ...
• SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication

  Caitlin Connolly, et al., bioRxiv - Cell Biology 2021

  Quote: CDC6 - Rabbit monoclonal [EPR714(2)] (Abcam, ab109315)
• MAP2 is Differentially Phosphorylated in Schizophrenia, Altering its Function

  MJ Grubisha, et al., bioRxiv - Neuroscience 2020

  Quote: ... HM-2 antibody (Abcam, Cambridge, MA, USA) was incubated together with washed Dynabeads (8μg antibody per mg beads used ...
• Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways

  F Quessy, et al., bioRxiv - Neuroscience 2021

  Quote: ... including 40,6-diamidino-2-phenylindole (Abcam, Ab104139). A Zeiss LSM700 confocal microscope was used for TH morphological and pERK/c-Fos colocalization expression for VTA analysis ...
• Characterization of sequence determinants of enhancer function using natural genetic variation

  Marty G. Yang, et al., bioRxiv - Genomics 2021

  Quote: ... 2 μg for anti-TEAD1 (Abcam ab133533), 2 μg for anti-CTCF (Active Motif (Carlsbad ...
• Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes

  Rajakumar Selvaraj, et al., bioRxiv - Cell Biology 2021

  Quote: ... perilipin 2 (PLIN2) (1:1000, Abcam #108323), calnexin (Cnx ...
• PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction

  Yuxin Wang, et al., bioRxiv - Biochemistry 2022

  Quote: ... 2) phospha-IRE1α (#ab48187, Abcam, Waltham, MA); 3 ...
• Role of human HSPE1 for OPA1 processing independent of HSPD1

  Nelson Yeung, et al., bioRxiv - Cell Biology 2022

  Quote: ... MFN1/2 (1:1,000 dilution, ab57602; Abcam), PDH (1:1,000 dilution ...
• H3.3 contributes to chromatin accessibility and transcription factor binding at promoter-proximal regulatory elements

  Amanuel Tafessu, et al., bioRxiv - Genomics 2022

  Quote: ... H3 general (ab1791, Abcam, Lot # GR177884-2), H3.3 (09-838 ...
• Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles

  Hyun Ji Kim, et al., bioRxiv - Genomics 2022

  Quote: ... The anti-Argonaut-2 antibody (Abcam, ab32381), anti-CD9 (Abcam ...
• Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

  Ester Gil Vazquez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... (2) Tenascin-C(1:600, ab108930; Abcam)-Opal 520 ...
• Mycobacterium tuberculosis-specific CD4 T cells expressing transcription factors associate with bacterial control in granulomas

  Nicole L. Grant, et al., bioRxiv - Immunology 2022

  Quote: ... IL-2 (Abcam, Cat. #ab119439, 1μL/10mL) and IL-7 (Abcam ...
• Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

  Sanjana Rajan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... hexokinase 2 (Abcam, [3D3] ab104836, 1:10), carbonic anhydrase 9 (Abcam ...
• Exploring the Connection between Autophagy and Heat-Stress Tolerance in Drosophila melanogaster

  Quentin Willot, et al., bioRxiv - Physiology 2023

  Quote: ... anti-Ref(2)P (ab178440, Abcam, Germany), and anti GABARAP1+ GABARAP2 (ab109364 Abcam ...
• Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity

  Seungyoon B. Yu, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Slc25a4/5 (ANT1/2) (Abcam), rabbit anti-Suclg1 (Cell signaling Technology) ...
• The Role of Respiratory Complex IV in Lifespan Length and Quality

  Beatriz Castejon-Vega, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ref(2)P (Abcam, ab178440, 1:1,000). Densitometry analyses on immunoblots were performed using Fiji (ver ...
• A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

  Lynn Bonetti, et al., bioRxiv - Immunology 2023

  Quote: ... Primary antibodies recognizing either claudin-2 (Abcam) or MUC2 (Abcam ...
• Coexisting morpho-biotypes unveil the regulatory bases of phenotypic plasticity in pancreatic ductal adenocarcinoma

  Pierluigi Di Chiaro, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-CEACAM6 (2 μg/ml, Abcam, #ab137859), anti-GABBR2 (1 μg/ml ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... 4’,6-Diamidino-2-phenylindole (DAPI, Abcam) was used for nuclear staining ...
• miR-210 expression is strongly hypoxia-induced in anaplastic thyroid cancer cell lines and is associated with extracellular vesicles & Argonaute-2

  Bonita H. Powell, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Albumin (abcam ab28405 Lot#GR3367930-2) diluted 1:1000 ...
• Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model

  Bhornprom Yoysungnoen, et al., bioRxiv - Physiology 2023

  Quote: ... VEGFR-2 (1:200; ab115805, Abcam, USA), MMP-2 (1:500 ...
• Acetylation-dependent coupling between G6PD activity and apoptotic signaling

  Fang Wu, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-Bcl-2 (Abcam, # ab196495; 1:1000). Unless stated otherwise ...
• Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons

  Wing Hei Au, et al., bioRxiv - Neuroscience 2023

  Quote: ... ref(2)P (1:1000, Abcam, ab178440) and GABARAP (1:1000 ...
• Quantitative Three-dimensional Label-free Digital Holographic Imaging of Cardiomyocyte Size, Ploidy, and Cell Division

  Sangsoon Park, et al., bioRxiv - Cell Biology 2023

  Quote: ... 6-diamidino-2-phenylindole (DAPI, AB2285492, Abcam) in order to stain nuclei prior to imaging on a Keyence BZ-X810 or Nikon TE300 inverted microscopes.
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-BCL-2 (ab182858, 1:2,000, Abcam), anti-Bax (ab32503 ...
• Aquaporin 1 confers apoptosis resistance in pulmonary arterial smooth muscle cells from the SU5416 hypoxia rat model

  Xin Yun, et al., bioRxiv - Cell Biology 2023

  Quote: ... Bcl-2 at 1:1,000 (ab196495, abcam) or BAX at 1:1000 (ab32503 ...
• Induction of apoptosis by double-stranded RNA was present in the last common ancestor of cnidarian and bilaterian animals

  Itamar Kozlovski, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... 2 mM cycloheximide (Abcam, Cambridge, United Kingdom) or an equivalent concentration of DMSO (Sigma-Aldrich ...
• Microinterfaces in bicontinuous hydrogels guide rapid 3D cell migration

  Karen L. Xu, et al., bioRxiv - Bioengineering 2023

  Quote: ... Ki67 antibodies (2 ug/mL, Abcam ab15580) were added in 3% BSA to the sections and incubated at 4°C overnight ...
• The renal capsule, a vibrant and adaptive cell environment of the kidney in homeostasis and aging

  Ben Korin, et al., bioRxiv - Immunology 2023

  Quote: ... Pax5 (Abcam rabbit monoclonal antibody EPR3730(2), 0.134 µg/ml) ...
• Altered astrocytic and microglial homeostasis characterizes a decreased proinflammatory state in bipolar disorder

  Quentin Amossé, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD44 (F10-44-2, abcam – 1/80) and SPP1 (ab63856 ...
• Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation

  Abhishek Kumar, Martin A Schwartz, bioRxiv - Cell Biology 2023

  Quote: ... rabbit monoclonal anti-Argonaute-2 ( Abcam, ab156870), rabbit polyclonal anti-DCP1A (Sigma ...
• Cultivation of host-adapted Cryptosporidium parvum and Cryptosporidium hominis using enteroids for cryopreservation of isolates and transcriptomic studies of infection

  Miner Deng, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit anti-mucin 2 (1:1000, Abcam) and rabbit anti-Ki-67 (1:500 ...
• Development of alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell derived liver organoids

  Zhiwei Feng, et al., bioRxiv - Cell Biology 2024

  Quote: ... 4’6-diamidino-2-phenylindole (DAPI; Abcam, UK) was used to counterstain the nuclei ...
• Opposing actions of JIP4 and RILPL1 provide antagonistic motor force to dynamically regulate membrane reformation during lysosomal tubulation/sorting driven by LRRK2

  Luis Bonet-Ponce, et al., bioRxiv - Cell Biology 2024

  Quote: ... rat anti-tyrosinated ⍺-tubulin (YL1/2) (Abcam, ab6160 ...