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251 - 300 of 2199 citations for 6 chloro 4 hydroxyquinoline 3 carboxylic acid since 2019

• Phosphorylation of pyruvate dehydrogenase marks the inhibition of in vivo neuronal activity

  Dong Yang, et al., bioRxiv - Neuroscience 2023

  Quote: ... (2R)-2-amino-5-phosphonopentanoic acid (AP5; Abcam, 50 μM) and Picrotoxin (Abcam ...
• Activation of the mevalonate pathway in response to anti-cancer treatments drives glioblastoma recurrences through activation of Rac-1

  Ling He, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Free Fatty Acid assay (ab65341, Abcam, Cambridge, UK) following the manufacturers’ instructions.
• GABAergic LRP1 is a key link between obesity and memory function

  Aaron Aykut Uner, et al., bioRxiv - Neuroscience 2023

  Quote: ... and free fatty acids (FFA) (ab65341, Abcam, Waltham, MA) were measured by enzyme linked immunosorbent assay (ELISA) ...
• Energy scarcity and impaired mitochondrial translation induce perinuclear stress granule clustering

  Uxoa Fernandez-Pelayo, et al., bioRxiv - Cell Biology 2024

  Quote: ... Koningic acid (KA) (Glentham life sciences, Abcam, Santa Cruz), Actinonin (ACT ...
• A small molecule that promotes cellular senescence prevents fibrogenesis and tumorigenesis in vitro

  Moon Kee Meang, et al., bioRxiv - Cell Biology 2022

  Quote: The caspase-3 activity was measured using a caspase-3 assay kit (Abcam, ab37401) following the manufacturer’s protocol ...
• Bosutinib stimulates macrophage survival, phagocytosis and intracellular killing of bacteria

  Ronni A. G. da Silva, et al., bioRxiv - Microbiology 2023

  Quote: Caspase 3 activity was measured using the Caspase-3 Activity Assay Kit (Fluorometric) (Abcam) as per the manufacturer’s instructions ...
• Farnesoid X Receptor suppresses lipid peroxidation and ferroptosis

  Juliane Tschuck, et al., bioRxiv - Cell Biology 2022

  Quote: ... For immunostaining with anti-4-Hydroxynonenal antibody (4-HNE, ab46545, Abcam) cells were treated with RSL3 and Ferrostatin-1 or Turofexorate/Fexaramine for 2 h before they were harvested with trypsin ...
• TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling

  Sushama Sivakumar, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and anti-Glypican-3 (Abcam). After an overnight incubation in primary antibodies ...
• Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

  Menghon Cheah, et al., bioRxiv - Neuroscience 2021

  Quote: ... 3-Methyladenine (2.5 mM, Abcam) and D4476 (10 µM ...
• Integrin-driven Axon Regeneration in the Spinal Cord Activates a Distinctive CNS Regeneration Program

  Menghon Cheah, et al., bioRxiv - Neuroscience 2021

  Quote: ... 3-Methyladenine (0.5 mM, Abcam) and D4476 (10 µM ...
• Drosophila ribosomal protein S5b is essential for oogenesis and interacts with distinct RNAs

  Jian Kong, et al., bioRxiv - Developmental Biology 2019

  Quote: ... a-cleaved Caspase 3 (Abcam), 1:200 ...
• Microbubble-Mediated Cavitation Promotes Apoptosis and Suppresses Invasion in AsPC-1 Cells

  J. Cao, et al., bioRxiv - Bioengineering 2020

  Quote: ... cleaved Caspase-3 (Abcam 13585), cleaved Caspase-8 (CST 9429) ...
• Cancer Cells in all EMT States Lack Rigidity Sensing Depletion of Different Tumor Suppressors Causes Loss of Rigidity Sensing in Cancer Cells

  Chloe Simpson, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Tropomyosin 3 (ab180813, Abcam), anti-α-Tubulin (ab7291 ...
• Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation

  Hae J. Park, et al., bioRxiv - Cancer Biology 2022

  Quote: ... cleaved caspase 3 (ab32042; Abcam), mTOR(#2972 and #2983 ...
• MONTE enables serial immunopeptidome, ubiquitylome, proteome, phosphoproteome, acetylome analyses of sample-limited tissues

  Jennifer G. Abelin, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 3 µL EPR11226 (Abcam, ab157210), 3 µL B-K27 (Abcam ...
• EZH2 endorses cell plasticity to carcinoma cells facilitating mesenchymal to epithelial transition and tumour colonization

  Amador Gallardo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... rabbit anti-Histone 3 (Abcam), rabbit anti-EZH2 (Diagenode) ...
• Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells

  Mara Doimo, et al., bioRxiv - Cell Biology 2022

  Quote: ... 2’,3’-dideoxycytidine (ddC, Abcam) was freshly dissolved in distilled water to 100 mM prior to cell treatment ...
• MiR-17-5p regulates proliferation and apoptosis of uterine fibroids via targeting ESR1

  Lan Luo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-caspase-3 (ab13585; Abcam), Anti-PCNA (ab29 ...
• The Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II

  Julie Carnesecchi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Histone 3 (Abcam, 1/10,000), GFP (Life Technologies ...
• Generation of human blastocyst-like structures from pluripotent stem cells

  Yong Fan, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-GATA2/3 (Abcam, ab182747 ...
• FoxP3 associates with enhancer-promoter loops to regulate Treg-specific gene expression

  Ricardo N. Ramirez, et al., bioRxiv - Immunology 2021

  Quote: ... 3 ug Yy1 (Abcam ab109237) and 5 ug rabbit IgG (Cell Signaling 2729S) ...
• Encephalitis patient derived monoclonal GABA_A receptor antibodies cause catatonia and epileptic seizures

  Jakob Kreye, et al., bioRxiv - Neuroscience 2021

  Quote: ... β3 (1:250, Abcam #ab4046), and γ2 (1:250 ...
• An intravenous DNA-binding priming agent protects cell-free DNA and improves the sensitivity of liquid biopsies

  Shervin Tabrizi, et al., bioRxiv - Genomics 2023

  Quote: ... 121-3 (cat. ab270732, Abcam), 35I9 (cat ...
• Galectin-9 interacts with Vamp-3 to regulate cytokine secretion in dendritic cells

  Rui Santalla Méndez, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Vamp-3 (ab5789, Abcam) at 1:1000 (v/v) ...
• Mitochondrial H₂O₂ release does not directly cause genomic DNA damage

  Daan M.K. van Soest, et al., bioRxiv - Cell Biology 2023

  Quote: ... and prdxSO2/3 (Abcam, ab16830).
• Analysis of the ubiquitin-modified proteome identifies novel host determinants of Kaposi’s sarcoma herpesvirus lytic reactivation

  Amerria Causey, et al., bioRxiv - Microbiology 2023

  Quote: ... SUMO 2/3 AB374 (Abcam), VDAC1 Sc-390996 (Santa Cruz) ...
• ER-to-lysosome Ca²⁺ refilling followed by K⁺ efflux-coupled store-operated Ca²⁺ entry in inflammasome activation and metabolic inflammation

  Hyereen Kang, et al., bioRxiv - Immunology 2023

  Quote: ... 3 μM Xestospongin C (Abcam), 10 μM dantrolene (Sigma) ...
• EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells

  Irini Topalidou, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal anti-syntaxin 6 (1:100, Abcam, #ab12370), rabbit polyclonal anti-CCDC186 (1:150 ...
• Human stem cell derived sensory neurons are positioned to support varicella zoster virus latency

  Tomohiko Sadaoka, et al., bioRxiv - Microbiology 2020

  Quote: ... mouse anti-Nav1.7 monoclonal antibody (clone N68/6, Abcam) (1:100) ...
• No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor

  Jarrod Shilts, Gavin J. Wright, bioRxiv - Biochemistry 2020

  Quote: ... and 1.3 μg/mL MEM-M6/6 (Abcam #ab119114)25 ...
• Antihypertensive effect of brain-targeted mechanical intervention with passive head motion

  Shuhei Murase, et al., bioRxiv - Bioengineering 2022

  Quote: ... PD123319 (10-6 mol/L in PBS; ab144564, Abcam), for 20 min ...
• The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule biogenesis

  Gaelle R. Carrat, et al., bioRxiv - Cell Biology 2020

  Quote: ... 6 μg of Rabbit IgG isotype control (Abcam, ab171870) or anti-PCTP-L (STARD10 ...
• An atypical F-actin capping protein modulates cytoskeleton behaviors crucial to colonization of Trichomonas vaginalis

  Kai-Hsuan Wang, et al., bioRxiv - Microbiology 2022

  Quote: ... mouse anti-6×His (2,000×, Abcam AD1.1.10, Cambridge, UK), rabbit anti-phospho-CKII substrate [(pS/pT)DXE] (1,000× ...
• Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer’s disease pathology

  Zhengrong Zhang, et al., bioRxiv - Neuroscience 2021

  Quote: ... 6) anti-NeuN antibody (#ab177487, Abcam, Cambridge, MA, USA) to identify neurons ...
• Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance

  Sumiko Takao, et al., bioRxiv - Cancer Biology 2022

  Quote: 5(6)-Carboxyfluorescein diacetate N-hydroxysuccinimidyl ester (CFSE, Abcam) was dissolved in DMSO at 5 mM and stored at −20 °C ...
• Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells

  Martin H. Berryer, et al., bioRxiv - Neuroscience 2022

  Quote: ... IL-6 concentration was measured by ELISA (Abcam, ab229334) in supernatants diluted 1:50 according to the manufacturer’s protocol (Abcam).
• Mechanical Force Imprints Neutrophils to Orchestrate Pulmonary Homeostasis

  Jin Wang, et al., bioRxiv - Immunology 2023

  Quote: ... and 5 µM Fluo-8 (Abcam 1345980-40-6) in HBSS (Solarbio ...
• Thiolation-Based Protein-Protein Hydrogels for Improved Wound Healing

  Xing Liu, et al., bioRxiv - Bioengineering 2023

  Quote: ... IL-6 and TNF-α (dilution 1:500, Abcam) were incubated with the membranes overnight at 4 °C ...
• Monocyte-derived microglia with Dnmt3a mutation cause motor pathology in aging mice

  Jung-Seok Kim, et al., bioRxiv - Immunology 2023

  Quote: ... Tmem119(106-6, Abcam cat. no. ab225494, RRID: AB_2744673), CD206 (C068C2 ...
• Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

  Aarti Singh, et al., bioRxiv - Cell Biology 2024

  Quote: ... 6-diamidino-2-phenylindole (DAPI) mounting solution (Abcam, ab104139).
• Lapatinib protects against epileptic seizures via halting glutathione peroxidase 4-dependent ferroptosis

  Jining Jia, et al., bioRxiv - Neuroscience 2020

  Quote: ... 4-hydroxynonenal (4-HNE) (rabbit, 17–76 kDa, ab46545, 1:2500, Abcam), acyl-CoA synthetase long-chain family member 4 (ACSL4 ...
• Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-derived Factor Receptor (PEDF-R)

  Jeanee Bullock, et al., bioRxiv - Biochemistry 2021

  Quote: A total of 50 μl of conditioned medium from ARPE-19 cell cultures were collected and used to quantify free fatty acids using the Free Fatty Acid Quantification Assay Kit (Colorimetric) (Abcam cat. # ab65341; Cambridge, MA) following manufacturer’s instructions.
• Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity

  Timothy D. Heden, et al., bioRxiv - Physiology 2019

  Quote: ... 4-HNE (Abcam, ab48506), DRP-1 (Abcam ...
• Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism

  Nirosha J. Murugan, et al., bioRxiv - Animal Behavior and Cognition 2020

  Quote: ... GsMTx-4 (Abcam, USA)(Gnanasambandam et al. ...
• Lactate promotes cardiomyocyte dedifferentiation through metabolic reprogramming

  Jesús Ordoño, et al., bioRxiv - Bioengineering 2020

  Quote: ... 4% goat serum (Abcam) in Tris-buffered saline containing 0.1% Tween® 20 (TBST ...
• The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing

  A.D. Podgurskaya, et al., bioRxiv - Biophysics 2019

  Quote: ... SSEA-4 (Abcam, ab16287) 1:50 ...
• Endothelial basement membrane laminins as an environmental cue in monocyte differentiation to macrophages.

  Lixia Li, et al., bioRxiv - Immunology 2020

  Quote: ... α4 (PS/2, Abcam), α3 (mouse polyclonal ...
• The mechanosensitive ion channel Piezo1 modulates the migration and immune response of microglia

  Ting Zhu, et al., bioRxiv - Neuroscience 2022

  Quote: ... GsMTx-4 (ab141871, abcam) were added in this step as needed ...
• Phosphatidylethanolamine facilitates mitochondrial pyruvate entry to regulate metabolic flexibility

  Piyarat Siripoksup, et al., bioRxiv - Physiology 2022

  Quote: ... 4-HNE (ab46545, Abcam), MPC1 (generated by Jared Rutter) ...
• Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI

  Alexander Kapustin, et al., bioRxiv - Cell Biology 2023

  Quote: ... Syndecan-4 (Abcam, ab24511), α-Actinin-4 (Abcam ...