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101 - 150 of 10000+ citations for 6 METHYL 2H PYRIDO 1 2 A PYRIMIDIN 2 ONE since 2019

• Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

  Sanjana Rajan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... hexokinase 2 (Abcam, [3D3] ab104836, 1:10), carbonic anhydrase 9 (Abcam ...
• The Role of Respiratory Complex IV in Lifespan Length and Quality

  Beatriz Castejon-Vega, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ref(2)P (Abcam, ab178440, 1:1,000). Densitometry analyses on immunoblots were performed using Fiji (ver ...
• Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

  Fei Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... SUMO-2/3 (1:250, ab3742; abcam), and TRF1 (1:200 ...
• Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model

  Bhornprom Yoysungnoen, et al., bioRxiv - Physiology 2023

  Quote: ... VEGFR-2 (1:200; ab115805, Abcam, USA), MMP-2 (1:500 ...
• Acetylation-dependent coupling between G6PD activity and apoptotic signaling

  Fang Wu, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-Bcl-2 (Abcam, # ab196495; 1:1000). Unless stated otherwise ...
• Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction in C9orf72 ALS/FTD in vivo models and patient iNeurons

  Wing Hei Au, et al., bioRxiv - Neuroscience 2023

  Quote: ... ref(2)P (1:1000, Abcam, ab178440) and GABARAP (1:1000 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-BCL-2 (ab182858, 1:2,000, Abcam), anti-Bax (ab32503 ...
• Aquaporin 1 confers apoptosis resistance in pulmonary arterial smooth muscle cells from the SU5416 hypoxia rat model

  Xin Yun, et al., bioRxiv - Cell Biology 2023

  Quote: ... Bcl-2 at 1:1,000 (ab196495, abcam) or BAX at 1:1000 (ab32503 ...
• Altered astrocytic and microglial homeostasis characterizes a decreased proinflammatory state in bipolar disorder

  Quentin Amossé, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD44 (F10-44-2, abcam – 1/80) and SPP1 (ab63856 ...
• Cultivation of host-adapted Cryptosporidium parvum and Cryptosporidium hominis using enteroids for cryopreservation of isolates and transcriptomic studies of infection

  Miner Deng, et al., bioRxiv - Microbiology 2023

  Quote: ... rabbit anti-mucin 2 (1:1000, Abcam) and rabbit anti-Ki-67 (1:500 ...
• Sensitivity of Olfactory Sensory Neurons to food cues is tuned to nutritional states by Neuropeptide Y signalling

  Tarun Kaniganti, et al., bioRxiv - Neuroscience 2019

  Quote: ... monoclonal anti-phosphorylated ERK 1/2 (1:500; Abcam) and polyclonal anti-TrpC2 (1:50 ...
• Hypoxia regulate developmental coronary angiogenesis potentially through VEGFR2- and SOX17-mediated signaling

  Halie E. Vitali, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Erg 1/2/3 (1:1000, Cat: ab92513, abcam), an endothelial cell nucleus antibody ...
• An Immunological Synapse Formation Between T Regulatory Cells and Cancer-Associated Fibroblasts Promotes Tumor Development

  Athina Varveri, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-VCAM-1 (1:500, Abcam, M/K-2), anti-Foxp3 (1:100 ...
• Circular RNA hsa_circ_0068033 inhibits proliferation and invasion of breast cancer cells through sponging miR-659

  Pengfei Yuan, Liangliang Lei, Dechun Liu, bioRxiv - Cancer Biology 2019

  Quote: ... Rabbit anti-human monoclonal primary antibody B-cell lymphoma-2 (Bcl-2) (Abcam, 1:1,000) and mouse anti-human GAPDH monoclonal primary antibody (Abcam ...
• Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein

  Sara Elfarrash, et al., bioRxiv - Neuroscience 2021

  Quote: ... Antibodies used were α-syn aggregate-specific antibody MJF-14 (rabbit monoclonal MJFR-14-6-4-2, #ab209538, Abcam, 1:25,000) and mouse monoclonal pS129-α-syn (11A5 ...
• Terpenes from Cannabis sativa Induce Antinociception in Mouse Chronic Neuropathic Pain via Activation of Spinal Cord Adenosine A_2A Receptors

  Abigail M. Schwarz, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1% bovine serum albumin in PBS with 0.1% Tween20 [PBST]) for one hour at RT and left overnight in the A2AR primary antibody at 4°C (Abcam #ab3461, Lot # GR3431019-2, 1:100) in blocking solution ...
• The Expression of Vesicular Glutamate Transporter 1 (VGLUT1) in the Rat Larynx and Implications for Laryngeal Proprioception

  Victoria X. Yu, et al., bioRxiv - Neuroscience 2023

  Quote: Coverslips were mounted with Fluoroshield Mounting Medium with 4’,6-diamidino-2-phenylindole (DAPI) (Abcam) and stored at 4ºC ...
• HSPA8-mediated stability of the CLPP protein regulates mitochondrial autophagy in cisplatin-resistant ovarian cancer cells

  Xinxin Kou, Xiaoxia Yang, Zheng Zhao, Lei Li, bioRxiv - Cancer Biology 2023

  Quote: ... the cell nuclei were stained with 4’,6-diamidino-2-phenylindole staining solution (ab104139, Abcam) at an ambient temperature ...
• TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8⁺ T cells

  Helen Carrasco Hope, et al., bioRxiv - Immunology 2022

  Quote: ... T cells were treated with either the fluorescent glucose analogue 2- (N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG, 50μM, 1h, Abcam) or kynurenine (800μM in HBSS buffer ...
• Lineage and Spatial Mapping of Glioblastoma-associated Immunity

  Vidhya M. Ravi, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Interleukin 2 (IL-2, Abcam, Cambridge, UK) was used at a final concentration of 1 ng/ml ...
• Mouse Memory CD8 T cell subsets defined by Tissue Resident Memory (T_RM) Integrin Expression Exhibit Distinct Metabolic Profiles

  Mike Sportiello, et al., bioRxiv - Immunology 2023

  Quote: 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2-NBDG) (Abcam Catalog No. ab146200) was dissolved in DMSO to yield a 20 mM stock solution ...
• Heme oxygenase-2 (HO-2) binds and buffers labile heme, which is largely oxidized, in human embryonic kidney cells

  David A. Hanna, et al., bioRxiv - Cell Biology 2021

  Quote: ... HO-2 and HO-1 were probed with a 1:1,000 dilution of rabbit anti HO-2 antibody (Abcam 90515) or 1:1,000 rabbit anti HO-1 (Enzo Life Sciences BML- HC3001-0025 ...
• Myosin-X and talin modulate integrin activity at filopodia tips

  Mitro Miihkinen, et al., bioRxiv - Cell Biology 2021

  Quote: ... and kindlin-1 (recognizes kindlin 1 and 2, Abcam, ab68041).
• Kif6 regulates cilia motility and polarity in brain ependymal cells

  Maki Takagishi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... or anti-Tubulin [YL 1/2] (1:200, Abcam, ab6160), were detected with secondary antibodies conjugated to Alexa Fluorophores (Invitrogen) ...
• FLS2 is a CDK-like kinase that directly binds IFT70 and is required for proper ciliary disassembly in Chlamydomonas

  Qin Zhao, et al., bioRxiv - Cell Biology 2019

  Quote: ... 2 μg MBP and 1 mM ATPγS (Abcam)) ...
• Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification

  Asra Almubarak, et al., bioRxiv - Developmental Biology 2021

  Quote: ... COLX (Abcam, ab5832, lot GR3210868-2, 1:50); COL I (Abcam ...
• A Highly Conserved Shh Enhancer Coordinates Hypothalamic and Craniofacial Development

  Zoe Crane-Smith, et al., bioRxiv - Developmental Biology 2020

  Quote: ... rabbit anti-NKX2-2 (1:250, Abcam, ab191077); rabbit anti-NKX6-1 (1:250 ...
• Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains

  Elana Bryan, et al., bioRxiv - Molecular Biology 2021

  Quote: ... CBX7 (abcam, AB21873, lots GR3210651-1 and −2), EZH2 (BD Biosciences ...
• Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling

  Beatriz Garcia-Diaz, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-p-EphB1+2 (1:300, ab61791, Abcam), anti-p-EphA4 (1:300 ...
• Human induced pluripotent stem cell-derived three-dimensional cardiomyocyte tissues ameliorate the rat ischemic myocardium by remodeling the extracellular matrix and cardiac protein phenotype

  Junya Yokoyama, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-heparan sulfate proteoglycan 2 (1:100; Abcam), anti-desmin (1:100 ...
• A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes corpus luteum regression

  Dianrong Li, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-MEK1/2 (ab178876, abcam; WB, 1:1000). Donkey anti-Mouse ...
• A role for thalamic projection GABAergic neurons in circadian responses to light

  O. Brock, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-calbindin 2 (1:200, ab702, Abcam), rabbit anti-vGAT (1:2000 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... Microtubule Associated Protein 2 (MAP2; 1:300; Abcam), Neurofilament 200 (NF200 ...
• UCHL1 inhibited by A1 astrocytes facilitates aggregates clearance to promote neural stem cells activation after spinal cord injury

  Lu Ding, et al., bioRxiv - Neuroscience 2021

  Quote: ... nuclear related factor 2 (Nrf2; 1:1000; Abcam), C3 (1:1000 ...
• APC-mutant cells exploit compensatory chromosome alterations to restore tumour cell fitness

  Yoshihiro Kawasaki, et al., bioRxiv - Cell Biology 2021

  Quote: ... clone YL1/2 (ab6160; Lot# GR57687-1; Abcam); rabbit anti-γ-tubulin pAb (ab11320 ...
• Evaluation of folliculin detection by immunohistochemistry in Birt-Hogg-Dubé associated kidney tumors

  Iris E. Glykofridis, et al., bioRxiv - Genetics 2022

  Quote: ... Ab #2 (1:500 in milk, ab93196, Abcam), Ab #3 (1:1000 in BSA ...
• SARS-CoV-2 infection, neuropathogenesis and transmission among deer mice: Implications for reverse zoonosis to New World rodents

  Anna Fagre, et al., bioRxiv - Microbiology 2020

  Quote: ... microtubule-associated protein 2 (Abcam; ab32454; 1:500), ionized calcium binding adaptor molecule 1 (Abcam ...
• Extracellular Pgk1 enhances neurite outgrowth of motoneurons through Nogo66-independent targeting of NogoA

  Cheng Yung Lin, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Microtubule-associated protein 2 (MAP2) (Abcam; 1:1000), α-tubulin (SA ...
• Non-cell autonomous OTX2 transcription factor regulates anxiety-related behavior in the mouse

  C. Vincent, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-tryptophan hydroxylase 2 (rabbit, abcam, 1/500); anti-OTX2 (mouse monoclonal ...
• Cannabidiol effects on cocaine-seeking behaviour and incubation of craving in mice

  Laia Alegre-Zurano, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-pERK1/2 (1:2500; Abcam; #ab50011; RRID:AB_1603684), anti-GluA1 (1:1000 ...
• NSC348884 cytotoxicity is not mediated by inhibition of nucleophosmin oligomerization

  Markéta Šašinková, et al., bioRxiv - Cell Biology 2020

  Quote: ... Rabbit monoclonal anti-PAK1 (1:2 000, Abcam) and anti-PAK1-pSer144 (1:20 000 ...
• A molecular cell atlas of the human lung from single cell RNA sequencing

  Kyle J. Travaglini, et al., bioRxiv - Genomics 2020

  Quote: ... Carbonic Anhydrase 2 (rabbit, Abcam EPR19839, 1:100). Primary antibodies were detected with Alexa Fluor-conjugated secondary antibodies (Jackson ImmunoResearch ...
• Myoscaffolds reveal laminin scarring is detrimental for stem cell function while sarcospan induces compensatory fibrosis

  Kristen M. Stearns-Reider, et al., bioRxiv - Cell Biology 2022

  Quote: ... and laminin alpha-2 (AB11576; 1:150; Abcam). Primary antibodies were detected by biotinylated anti-rabbit (BA-1000 ...
• Translation of dipeptide repeat proteins in C9ORF72-ALS/FTD through unique and redundant AUG initiation codons

  Yoshifumi Sonobe, et al., bioRxiv - Molecular Biology 2022

  Quote: ... and α-tubulin (1:5000, YL1/2, Abcam). Following washing ...
• Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

  Aitor Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: ... ref(2)P/p62 (Abcam, ab178440, 1:1000), PINK1 (Cell Signaling Technology ...
• FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provides a target for Pink1 phosphorylation in vivo

  Alvaro Sanchez-Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: ... ref(2)P/p62 (Abcam ab178440, 1:1000). The following secondary antibodies were used ...
• A novel interaction between the 5’ untranslated region of the Chikungunya virus genome and Musashi RNA binding protein is essential for efficient virus genome replication

  Kaiwen Sun, et al., bioRxiv - Microbiology 2023

  Quote: ... MSI-2 (1:1000 rabbit monoclonal, Abcam ab76148) and MSI-1 (1:5000 ...
• Virally induced lipid droplets are a platform for innate immune signalling complexes

  EA Monson, et al., bioRxiv - Immunology 2023

  Quote: ... rabbit monoclonal αPerilipin-2 (1:2000; ab108323, Abcam), mouse monoclonal αRIG-I (1:1000 ...
• Foxg1 regulates translation of neocortical neuronal genes, including the main NMDA receptor subunit gene, Grin1

  Osvaldo Artimagnella, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit monoclonal [EPR2481(2)] (Abcam #ab109182, 1:500); anti-Grin1 NH2-term ...
• Inherited retinal degeneration: T-type voltage-gated channels, Na⁺/Ca²⁺-exchanger and calpain-2 promote photoreceptor cell death

  Jie Yan, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit-anti-calpain-2 (1:200; ab39165; Abcam), rabbit-anti-calpain-1 (1:100 ...