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251 - 300 of 2030 citations for 6 Chloro 2 3 dihydro 2 7 dimethylbenzofuran since 2019

• KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster

  Meghna Singh, et al., bioRxiv - Genomics 2023

  Quote: ... 2 ul of H3K23ac (AbCam #ab177275), and 4ul of IGg (Cell signaling #2729 ...
• Liver-specification of human iPSC-derived endothelial cells transplanted into mouse liver

  Kiryu K. Yap, et al., bioRxiv - Cell Biology 2023

  Quote: ... Stabilin-2 (1:100, ab121893, Abcam), and Factor VIII (1:100 ...
• The establishment of HP1-independent heterochromatin reveals an essential role for HP1 proteins in maintaining epigenetic memory

  Melissa Seman, et al., bioRxiv - Genetics 2023

  Quote: ... 2 µg H3K9me2 antibody (Abcam, ab1220), 2µg H3K9me3 antibody (39161 ...
• ATRX guards against aberrant differentiation in mesenchymal progenitor cells

  Yan Fang, et al., bioRxiv - Genetics 2023

  Quote: ... 2 µg ATRX antibody (Abcam, ab97508) was added ...
• ZC3H11A mutations cause high myopia by triggering PI3K-AKT and NF-κB mediated inflammatory reactions in humans and mice

  Chong Chen, et al., bioRxiv - Genetics 2023

  Quote: ... and MMP-2 (ab92536, Abcam, UK) diluted to 1:1000 in TBST-5% milk ...
• Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

  Callum Beach, et al., bioRxiv - Cancer Biology 2023

  Quote: ... (2) CD34 (1:3000, ab81289; Abcam)–Opal 520 ...
• Endocytosis is regulated through the pH-dependent phosphorylation of Rab GTPases by Parkinson’s kinase LRRK2

  Michelle E. Maxson, et al., bioRxiv - Cell Biology 2023

  Quote: ... MLi-2 was purchased from Abcam. Fluorescent conjugated 10 kDa dextrans were purchased from Invitrogen ...
• MicroRNA-22, Specificity protein-1 and Cystathionine β-synthase in early onset Preeclampsia: significance in trophoblast invasion

  Pallavi Arora, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies to MMP-2 (Abcam) at a dilution of 1:500 ...
• Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model

  Bhornprom Yoysungnoen, et al., bioRxiv - Physiology 2023

  Quote: ... MMP-2 (1:500; ab86607, Abcam), MMP-9 (1:500 ...
• Growth factor-free, peptide-functionalized gelatin hydrogel promotes arteriogenesis and attenuates tissue damage in a murine model of critical limb ischemia

  Corinne W. Curry, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 2) CD31 (1:100; Abcam) and α-SMA ...
• The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

  Huishan Wang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-H3K27me3 (2 μg, Abcam, ab192985), or anti-H3K4me3 antibodies (2 μg ...
• Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)

  Ting Zhang, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... 2 μg H3K9me3 antibody (ab8898; Abcam), 2 μg CEBPB antibody (PA5-27244 ...
• Histone H3 E50K mutation confers oncogenic activity and supports an EMT phenotype

  K Sad, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H3K4me1 (Abcam 8899; 2 µg/ml), H3K27me3 (CST 9733S ...
• Induction of apoptosis by double-stranded RNA was present in the last common ancestor of cnidarian and bilaterian animals

  Itamar Kozlovski, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... 2 mM cycloheximide (Abcam, United Kingdom), or an equivalent concentration of DMSO in 24-well plate containing 500 µL N ...
• Extracellular RNA induce neutrophil recruitment via endothelial TLR3 during venous thrombosis after vascular injury

  Maria Y. Najem, et al., bioRxiv - Physiology 2024

  Quote: ... a rat anti-MOMA-2 (Abcam) and rabbit anti-mouse CitH3 (Abcam ...
• ENDOTHELIAL GENE REGULATORY ELEMENTS ASSOCIATED WITH CARDIOPHARYNGEAL LINEAGE DIFFERENTIATION

  Ilaria Aurigemma, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and 2 μM Forskolin (Abcam, ab120058). The Induction Medium was changed after one day ...
• Microtubule reorganization during mitotic cell division in the dinoflagellate Ostreospis cf. ovata

  David Velasquez-Carvajal, et al., bioRxiv - Cell Biology 2023

  Quote: ... YL1/2 antibody (ab6160; rat, Abcam) was used at 1:400 dilution ...
• Helicobacter pylori cancer associated CagA protein drives intestinal metaplastic transition in human gastric organoids

  Mar Reines, et al., bioRxiv - Cell Biology 2023

  Quote: ... Claudin-2 (Abcam Cat. No. ab53032), β-Actin (Sigma ...
• Alpha Synuclein Modulates Mitochondrial Ca²⁺ Uptake from ER During Cell Stimulation and Under Stress Conditions

  Meraj Ramezani, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:400 dilution) and anti-α- synuclein aggregate antibody (Clone#: MJFR-14-6-4-2; 1:1000 dilution) were acquired from Abcam (Cambridge UK).
• A CTLA-4 nanobody improves the immunity of mice against challenges with Staphylococcus aureus and Streptococcus agalactiae

  Peng Wu, Ningning Yang, Mingguo Xu, Chuangfu Chen, bioRxiv - Cell Biology 2021

  Quote: ... and incubated at RT for 2 h with mouse anti-CTLA-4 monoclonal antibody (diluted: 1:3 000; Abcam, Cambridge, UK) as the primary antibody ...
• Waves of sumoylation support transcription dynamics during adipocyte differentiation

  Xu Zhao, et al., bioRxiv - Genomics 2021

  Quote: ... were used to capture 400 μL of SUMO-2/3 antibody (8A2, acquired from Abcam, ab81371; ∼5-10 μg/μL antibody). All washing and handling steps were followed by centrifugation of the beads at 500g for 3 min in a swing-out centrifuge with delayed deceleration and careful aspiration of buffers ...
• Loss of Grin2a Causes a Transient Delay in the Electrophysiological Maturation of Hippocampal Parvalbumin Interneurons: A Possible Mechanism for Transient Seizure Burden in Patients with Null GRIN2A Variants

  Chad R. Camp, et al., bioRxiv - Neuroscience 2023

  Quote: ... Slices were then washed 3 times in 1x PBS for 10 minutes then incubated in DAPI counterstain (Abcam, ab228549; 2 µM) for 30 minutes before being washed 3 more times in 1x PBS for 10 minutes ...
• Brain transcriptomics reveals features of the host response after dengue virus type I infection induced central nervous system injury in AGB6 mice

  Ning Yu, et al., bioRxiv - Immunology 2024

  Quote: ... sections were repaired using EDTA antigen recovery buffer and incubated overnight at 4 °C with anti-dengue virus 1+2+3+4 primary antibody (Abcam, ab26837). Next ...
• DNA Methylation Patterns Expose Variations in Enhancer-Chromatin Modifications during Embryonic Stem Cell Differentiation

  Adi Alajem, et al., bioRxiv - Molecular Biology 2020

  Quote: Antibodies (H3K4me1 abcam ab8895, H3K27Ac abcam ab4729, H3K36me abcam ab9050, 2 μg antibody per 2×107 cells) were incubated with 25 μL protein A Dynabeads (Thermo Scientific ...
• Genome-wide analysis reveals a switch in the translational program upon oocyte meiotic resumption

  Xuan G. Luong, et al., bioRxiv - Developmental Biology 2019

  Quote: ... 2 µl (2 µg) of the appropriate antibody (anti-CPEB: Abcam, ab73287 and control IgG: Abcam, ab172730) was added to each tube ...
• Borrowing Transcriptional Kinases to Activate Apoptosis

  Roman Sarott, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 50 µg of chromatin was used with anti-Pol II ser 2 phos (2 µg, Abcam ab5095) and anti-Pol II ser 5 phos (2 µg ...
• Testosterone improves muscle function of the extensor digitorum longus in rats with sepsis

  Jinlong Wang, Tong Wu, bioRxiv - Pathology 2019

  Quote: ... Soluble proteins (20 μg) were used for Western blotting with primary antibodies against AKT1/2/3 (rabbit monoclonal antibody; EPR16798 Abcam; 1:10,000), mTOR (rabbit monoclonal antibody ...
• Esrrb is a cell cycle dependent XEN priming factor balancing between pluripotency and differentiation

  Sapir Herchcovici Levi, et al., bioRxiv - Molecular Biology 2021

  Quote: ChIP Antibodies (H3K4me1 abcam ab8895, H3K27Ac abcam ab4729, H3K36me abcam ab9050, 2 µg antibody per 2×107 cells) were incubated with 25 µL protein A Dynabeads (Thermo Scientific ...
• DDHD2 provides a critical flux of saturated fatty acids to support neuronal energy demands

  Saber H. Saber, et al., bioRxiv - Neuroscience 2024

  Quote: ... Neurons were then immunostained against endogenous AP-2 using Anti-AP-2 complex subunit alpha-1 (Abcam, #ab218624) diluted in blocking solution (1% BSA in PBS ...
• The desmosomal cadherin Desmoglein-3 regulates YAP and phospho-YAP in keratinocyte responses to mechanical forces

  Jutamas Uttagomol, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit Ab to LATS1+2 (ab70565, Abcam), normal rabbit IgG (2729S ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... and RFC1 (ab3566, Abcam, 2 μg/IP). Antibodies used for immunofluorescence included ...
• A concurrent canonical and modified miRNAome pan-cancer study on TCGA and TARGET cohorts leads to an enhanced resolution in cancer

  Rosario Distefano, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Anti- AGO-2 (Novus) and Vinculin (Abcam) antibodies were used for western blotting analysis.
• The dynamic chromatin architecture of the regenerating liver

  Amber W. Wang, et al., bioRxiv - Genomics 2019

  Quote: ... or anti-HNF4α (2 μg, ab181604, Abcam) antibodies in dilution buffer (16.7 mM Tris-HCl pH 8.1 ...
• Topoisomerase VI participates in an insulator-like function that prevents H3K9me2 spreading into euchromatic islands

  Louis-Valentin Méteignier, et al., bioRxiv - Plant Biology 2019

  Quote: ... anti-H3K27me3 (Abcam ab6002, lot: GR275911-2), anti-H3K9me2 ...
• Hap2-Ino80 facilitated transcription promotes de novo establishment of CENP-A chromatin

  Puneet P. Singh, et al., bioRxiv - Molecular Biology 2019

  Quote: ... 2 µl of RNAPII S2P (Abcam, ab5095) and 2 µl of RNAPII S5P (61085 ...
• Hap2-Ino80 facilitated transcription promotes de novo establishment of CENP-A chromatin

  Puneet P. Singh, et al., bioRxiv - Molecular Biology 2019

  Quote: ... 2 µl of anti-RNAPII (ab817, Abcam), 2 µl of RNAPII S2P (Abcam ...
• Hap2-Ino80 facilitated transcription promotes de novo establishment of CENP-A chromatin

  Puneet P. Singh, et al., bioRxiv - Molecular Biology 2019

  Quote: ... 2 µl of anti-H3 (ab1791, Abcam), 2 µl of anti-T7 (69522 ...
• Endogenous TDP-43 prevents retrotransposons activation through Dicer-2 activity and the RNA silencing machinery in Drosophila neurons

  Giulia Romano, Raffaella Klima, Fabian Feiguin, bioRxiv - Cell Biology 2019

  Quote: ... anti Dcr-2 (1:300 #ab4732, ABCAM), anti h-Dicer (1:3000 ...
• Mouse CHD4-NURD is required for neonatal spermatogonia survival and normal gonad development

  Rodrigo O. de Castro, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-CHD4 (2 μg, Abcam ab72418), or rabbit IgG (5μg Jackson ImmunoResearch ...
• Environmentally-induced mdig is a major contributor to the severity of COVID-19 through fostering expression of SARS-CoV-2 receptor NRPs and glycan metabolism

  Qian Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-SARS-CoV-2-Spike (Abcam, ab272504), anti-Furin (Abcam ...
• Dietary Vitamin B₁₂ reduces amyloid-β proteotoxicity by alleviating oxidative stress and mitochondrial dysfunction

  Andy B. Lam, Kirsten Kervin, Jessica E. Tanis, bioRxiv - Cell Biology 2021

  Quote: ... NUO-2 (Abcam cat#ab14711, 1:5000), α-tubulin (Sigma cat#T9026 ...
• A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation

  Yoshifumi Sonobe, et al., bioRxiv - Neuroscience 2020

  Quote: ... or tubulin (1:5000, YL1/2, Abcam). Following washing ...
• Cetuximab produced from a goat mammary gland expression system is equally efficacious as innovator cetuximab in model systems of cancer

  Qian Wang, et al., bioRxiv - Bioengineering 2020

  Quote: ... 2 equivalents of Cy5-maleimide (Abcam ab146489) was added and incubated 30 min at room temperature ...
• Temporal and spatial modulation of the immune response of the murine Gl261 glioma tumor microenvironment

  Kelly J McKelvey, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Panel 2: ARG1 (0.125μg/ml; ab91279; Abcam), iNOS (8μg/ml ...
• Pharmacodynamic Markers of LRRK2 Inhibition in Biofluids

  Shijie Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-LRRK2 (clone MJFF2 c41-2, Abcam), anti-pS935 LRRK2 (clone UDD2-10 ...
• Ultrasound-mediated mechanical forces selectively kill tumor cells

  Ajay Tijore, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Calpain 2 (rabbit, 1:1000, Abcam, ab39165), Piezo1 (rabbit ...
• Bromodomain factor 5 is an essential transcriptional regulator of the Leishmania genome

  Nathaniel G. Jones, et al., bioRxiv - Cell Biology 2021

  Quote: ... 2 μl (500 Units) BaseMuncher Endonuclease (Abcam). The lysate was sonicated 3 × 10 seconds at 40% amplitude using a probe sonicator (Sonics Vibra-Cell ...
• Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

  Charlene Lancaster, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 5 µM dynole 34-2 (Abcam). For clathrin inhibitors ...
• Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

  Vasiliki-Ilya Gargareta, et al., bioRxiv - Neuroscience 2022

  Quote: ... sirtuin 2 (SIRT2, Abcam #ab67299, 1:500), immunoglobulin superfamily member 8 (IGSF8 ...
• Reconstructing cell interactions and state trajectories in pancreatic cancer stromal tumoroids

  Ryo Okuda, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Lipocalin-2 (1:100, Abcam, ab23477), anti-E-cadherin (1:100 ...