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401 - 450 of 1897 citations for 3 hydroxy 20 oxopregn 5 en 21 yl acetate since 2020

• Pervasive promoter hypermethylation of silenced TERT alleles in human cancers

  D Esopi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 5 μL H3K27ac (ab4729 abcam), or 4 μL IgG (2729 ...
• Loss of BCL-3 sensitises colorectal cancer cells to DNA damage, revealing a role for BCL-3 in double strand break repair by homologous recombination

  Christopher Parker, et al., bioRxiv - Cancer Biology 2021

  Quote: ... CENPF (1:500, Abcam #5) diluted in 1% BSA ...
• Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

  Charlene Lancaster, et al., bioRxiv - Cell Biology 2021

  Quote: ... 5 µM dyngo-4a (Abcam) and 5 µM dynole 34-2 (Abcam) ...
• NRP2 as an emerging angiogenic player; promoting endothelial cell adhesion and migration by regulating recycling of α5 integrin

  Abdullah AA Alghamdi, et al., bioRxiv - Cell Biology 2020

  Quote: ... claudin-5 (clone ab131259, Abcam), VE-cadherin (clone ab205336 ...
• Phosphorylation triggers presynaptic phase separation of Liprin-α3 to control active zone structure

  Javier Emperador-Melero, et al., bioRxiv - Neuroscience 2021

  Quote: ... H-89 (5 µM, Abcam), bisindolylmaleimide-I (Bis-I ...
• A Newly Identified Role for IL-22 in Bladder Immunity

  Jared Honeycutt, et al., bioRxiv - Immunology 2020

  Quote: ... rabbit anti-cytokeratin 5 (Abcam), or isotype controls and goat secondary antibodies (Invitrogen) ...
• A transcriptional mechanism involving R-loop, m6A modification and RNA abasic sites regulates an enhancer RNA of APOE

  Jason A. Watts, et al., bioRxiv - Molecular Biology 2022

  Quote: ... or 5 μg H3K4me1 (Abcam) and recovered with Protein G agarose beads ...
• HOMOCYSTEINE POTENTIATES AMYLOID β-INDUCED CEREBRAL ENDOTHELIAL CELL APOPTOSIS, BLOOD BRAIN BARRIER DYSFUNCTION AND ANGIOGENIC IMPAIRMENT

  Ashley Carey, et al., bioRxiv - Neuroscience 2023

  Quote: ... phosphorylated Claudin-5 (abcam; ab172968), phosphorylated VeCadherin (Invitrogen ...
• Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI

  Alexander Kapustin, et al., bioRxiv - Cell Biology 2023

  Quote: ... α5 integrin (P1D6, Abcam, ab78614), Myo10 (Sigma ...
• Systematic analysis of the target recognition and repression by the Pumilio proteins

  Svetlana Farberov, Igor Ulitsky, bioRxiv - Molecular Biology 2024

  Quote: ... FAM120A (5 ug, Abcam, ab156695), or Rabbit IgG as a negative control at room temperature for 1 hr in gentle rotation.
• Systematic analysis of the target recognition and repression by the Pumilio proteins

  Svetlana Farberov, Igor Ulitsky, bioRxiv - Molecular Biology 2024

  Quote: ... PUM2 (5 ug, Abcam, ab10361), FAM120A (5 ug ...
• Prostate-specific membrane receptor PPAP facilitates E. coli invasion of luminal prostate cells via FimH binding

  Maria Guedes, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Anti-Cytokeratin 5 (ab52635, Abcam), anti-Cytokeratin 5 Alexa Fluor® 647 antibody (ab193895 ...
• Revealing a hidden conducting state by manipulating the intracellular domains in K_V10.1 exposes the coupling between two gating mechanisms

  Reham Abdelaziz, et al., bioRxiv - Biophysics 2024

  Quote: ... and 5 µM Thapsigargin (Abcam) were added to the bath ...
• Liver CYP4A autophagic-lysosomal degradation (ALD): A major role for the autophagic receptor SQSTM1/p62 through an uncommon target interaction site

  Liang He, et al., bioRxiv - Cell Biology 2024

  Quote: ... CYP4A antibody (5 μg, Abcam) was added ...
• Subcutaneous Neurotrophin-3 infusion induces corticospinal neuroplasticity and improvements in dexterity and walking in elderly rats after large cortical stroke

  Denise Duricki, et al., bioRxiv - Neuroscience 2021

  Quote: ... NT-3 was measured by standard ELISA according to manufacturer’s instructions (ab100615 – Neurotrophin 3 human ELISA Kit, abcam, Cambridge, United Kingdom).
• Regulation of Polyhomeotic condensates by intrinsically disordered sequences that affect chromatin binding

  Ibani Kapur, Elodie L. Boulier, Nicole J. Francis, bioRxiv - Biochemistry 2022

  Quote: ... Protein tech 50430-2-AP), anti-RFP (rabbit, 1:3 000, St. Johns Laboratory STJ97083) and anti-H2B (mouse, 1:3 000, Abcam, ab52484). Membranes were washed 3 times for 10 min each in PBST ...
• Alzheimer’s-like remodeling of neuronal ryanodine receptor in COVID-19

  Steve Reiken, et al., bioRxiv - Pathology 2021

  Quote: ... tissue proteins (20 μg) were separated by 4-20% SDS-PAGE and immunoblots were developed using antibodies against pSMAD3 (Abcam, 1:1000), SMAD3 (Abcam ...
• Multiscale activity imaging in mammary gland reveals how oxytocin enables lactation

  Alexander J. Stevenson, et al., bioRxiv - Cell Biology 2020

  Quote: ... Pre-treatments with ML-7 (20 μM, Abcam, Ab120848), Y27632 (10 μM ...
• Aging reduces calreticulin expression and alters spontaneous calcium signals in astrocytic endfeet of the mouse dorsolateral striatum

  Sara M. Zarate, et al., bioRxiv - Neuroscience 2021

  Quote: ... 20 µM cyclopiazonic acid (CPA, Abcam, Cambridge, MA, ab120300) was perfused into the bath for 15 min ...
• Reconstitution of human kinetochore in mitotic cell extracts reveals permitted and restricted assembly steps

  Ekaterina V. Tarasovetc, et al., bioRxiv - Cell Biology 2020

  Quote: ... biotinylated anti-GFP antibodies (20 µg ml−1, Abcam), or biotinylated anti-rabbit antibodies (30 µg ml−1 ...
• Cerebral organoid model reveals excessive proliferation of human caudal late interneuron progenitors in Tuberous Sclerosis Complex

  Oliver L. Eichmüller, et al., bioRxiv - Neuroscience 2020

  Quote: Organoids were treated with 20 nM of Everolimus (Abcam) as described5 ...
• Enhanced Neuronal Activity and Asynchronous Calcium Transients Revealed in a 3D Organoid Model of Alzheimer’s Disease

  Juan Yin, Antonius M. VanDongen, bioRxiv - Neuroscience 2020

  Quote: ... The anti-Oct4 antibodies (Catalog #ab109884, Abcam, 1:20), anti-Nanog antibody (Catalog #ab109884 ...
• Impact of glycoengineering and immunogenicity on the anti-cancer activity of a plant-made lectin-Fc fusion protein

  Matthew Dent, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 20 μL of MTS reagent (Abcam ab197010, Cambridge, UK) was added to each well and incubated for 4 hours ...
• Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2

  Tae Yoon Kim, et al., bioRxiv - Biochemistry 2020

  Quote: 20 μg of HER2 ectodomain from Abcam (Cambridge, UK) was mixed with 5-fold excess amount of a repebody and incubated at 4 °C overnight ...
• Mechano-arrhythmogenicity is enhanced during late repolarisation in ischemia and driven by a TRPA1-, calcium-, and reactive oxygen species-dependent mechanism

  Breanne A Cameron, T Alexander Quinn, bioRxiv - Physiology 2021

  Quote: ... or glibenclamide (20 μM, 15 min pre-incubation; Abcam).
• Synaptotagmin 7 is enriched at the plasma membrane through γ-secretase processing to promote vesicle docking and control synaptic plasticity in mouse hippocampal neurons

  Jason D. Vevea, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-TGN38/46 (1:20) (abcam; ab2809; RRID: AB_2203290), anti-EEA1 (1:50 ...
• The encoding of touch by somatotopically aligned dorsal column subdivisions

  Josef Turecek, Brendan P. Lehnert, David D. Ginty, bioRxiv - Neuroscience 2022

  Quote: ... NBQX (10 mM, 20 µL, Abcam, dissolved in H2O) was then applied to the surface of the cord ...
• Engineered SMCHD1 and D4Z4 mutations reveal roles of D4Z4 heterochromatin disruption and feedforward DUX4 network activation in FSHD

  Xiangduo Kong, et al., bioRxiv - Genetics 2022

  Quote: ... and separated by 4%–20% TEO-Tricine gel (Abcam). Then the samples were transferred to nitrocellulose membranes ...
• Targeting GDF15 as a potential therapy for low back pain originating from endplate

  Xiaoqun Li, et al., bioRxiv - Cell Biology 2023

  Quote: ... and rabbit anti-CD31 antibody (1:20; ab28364, Abcam) were used for CD31 and EMCN immunofluorescence staining ...
• Emergence of a somatosensory tonotopic map for substrate vibration in the brainstem

  Kuo-Sheng Lee, et al., bioRxiv - Neuroscience 2023

  Quote: ... NBQX (10 mM, 20 µl, Abcam, dissolved in H2O) was then applied to the surface of the cord ...
• Tobacco smoke exposure is a driver of altered oxidative stress response and immunity in head and neck cancer

  Y. Li, et al., bioRxiv - Cancer Biology 2024

  Quote: Cells were labeled with 20 µM DCFDA (ab113851, Abcam) for 30 min and then treated with various concentrations of smoke-infused media for 1h ...
• Calreticulin is required for cuticle deposition and trabeculae formation inside butterfly wing scale cells

  Ru Hong, Cédric Finet, Antónia Monteiro, bioRxiv - Developmental Biology 2024

  Quote: ... diluted 20 times in Universal Antibody Diluent (ab79995, Abcam), overnight at 4 ℃ ...
• Recruitment of transcriptional effectors by Cas9 creates cis regulatory elements and demonstrates distance-dependent transcriptional regulation

  Jubran Boulos, et al., bioRxiv - Genomics 2022

  Quote: ... and anti-Histone 3 k4 monomethyl (H3k4mm) (Abcam ab8895). Input controls were non-immune precipitated samples ...
• Age and neuroinflammation are important components of the mechanism of cognitive and neurobehavioral deficits in sickle cell disease

  Raven A. Hardy, et al., bioRxiv - Neuroscience 2020

  Quote: ... panel 3 = anti-mouse BrdU (ab8152, Abcam, 1:500), anti-mouse doublecortin (DCX ...
• The Ca²⁺-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

  Yang Guo, et al., bioRxiv - Physiology 2020

  Quote: ... Anti-Glyceraldehyde-3-phosphate dehydrogenase (GAPDH, 1:5000; Abcam) and anti-Histone H2B (1:5000 ...
• Destabilization of F-actin by Mechanical Stress Deprivation or Tpm3.1 Inhibition Promotes a Pathological Phenotype in Tendon Cells

  Kameron L. Inguito, et al., bioRxiv - Cell Biology 2022

  Quote: ... and rabbit anti-MMP-3 (1:10; EP1186Y, Abcam). Secondary antibodies used were anti-rabbit or anti-mouse HRP-conjugate (Protein Simple) ...
• Transcriptional activation of auxin biosynthesis drives developmental reprogramming of differentiated cells

  Yuki Sakamoto, et al., bioRxiv - Plant Biology 2021

  Quote: ... γ-butyrolactone (MB-3) (CAS 778649-18-6, Abcam)57 ...
• RNF5 Regulation of RBBP4 Defines Acute Myeloid Leukemia Growth and Susceptibility to Histone Deacetylase Inhibitors

  Ali Khateb, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mouse anti-glyceraldehyde 3-phosphate dehydrogenase (GAPDH; ab8245, Abcam), mouse anti-Tubulin (T9026 ...
• Functional characterisation of single nucleotide variants of the psychiatric risk gene cacna1c in the zebrafish

  Nancy Saana Banono, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-CaV1.3 antibody - C-terminal (3:100, #ab191038, Abcam) and monoclonal mouse anti-β actin antibody (1 ...
• KIF21B binds Myosin Va for Spine Entry and regulates Actin Dynamics to control Homeostatic Synaptic Downscaling

  Kira V. Gromova, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Shank1-3 (1:1,000; Abcam, Cambridge, UK), guinea pig anti-Synaptophysin (1:1,000 ...
• Age and neuroinflammation are important components of the mechanism of cognitive and neurobehavioral deficits in sickle cell disease

  Raven A. Hardy, et al., bioRxiv - Neuroscience 2020

  Quote: ... panel 3 = anti-mouse BrdU (ab8152, Abcam, 1:500), anti-mouse doublecortin (DCX ...
• Mechano-arrhythmogenicity is enhanced during late repolarisation in ischemia and driven by a TRPA1-, calcium-, and reactive oxygen species-dependent mechanism

  Breanne A Cameron, T Alexander Quinn, bioRxiv - Physiology 2021

  Quote: ... diphenyleneiodonium (DPI; 3 μM, 60 min pre-incubation; Abcam), or glibenclamide (20 μM ...
• The epigenetic landscape in purified myonuclei from fast and slow muscles

  Mads Bengtsen, et al., bioRxiv - Physiology 2021

  Quote: ... incubated for 3 hours with secondary antibody (Abcam #150083) at 4 °C with gentle agitation ...
• Systematic Phenotyping and Characterization of the 5xFAD mouse model of Alzheimer’s Disease

  Stefania Forner, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Fox 3 protein (NeuN; 1:1000; ab104225; Abcam), anti-Ctip2 (CTIP2 ...
• Targeting of TP53-independent cell cycle checkpoints overcomes FOLFOX resistance in Metastatic Colorectal Cancer

  Corina Behrenbruch, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Rabbit anti- Caspase-3 (cleaved) (Abcam – ab13847, 1:4000).
• The neurodevelopmental disorder-linked PHF14 complex that forms biomolecular condensates detects DNA damage and promotes repair

  Eva-Lotta Käsper, et al., bioRxiv - Molecular Biology 2021

  Quote: ... primary antibody solution (Sumo 2 + Sumo 3, abcam, ab3742) or already HRP-conjugated antibody (anti-GST-HRP ...
• Preferential lipolysis of DGAT1 over DGAT2 generated triacylglycerol in Huh7 hepatocytes

  Rajakumar Selvaraj, et al., bioRxiv - Cell Biology 2021

  Quote: ... glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (1:5000, Abcam #ab8245). Membranes were incubated with primary antibodies overnight (12-16 h ...
• A secreted proteomic footprint for stem cell pluripotency

  Philip Lewis, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1/300 rabbit L-Olfactomedin-like 3 (Abcam, ab111712); 1/500 mouse anti-Semaphorin 3A (R&D ...
• Large-scale mapping and systematic mutagenesis of human transcriptional effector domains

  Nicole DelRosso, et al., bioRxiv - Systems Biology 2022

  Quote: ... and Histone 3 antibody (1:1000, mouse, Abcam, AB1791) as primary antibodies ...
• Alternative Macrophage Activation Requires Granulocyte-Derived Lipids

  Tatyana Veremeyko, et al., bioRxiv - Immunology 2024

  Quote: ... 3) lysolipids: lysophosphatidic acid sodium salt (LPA, Abcam ab146430), lysophosphatidylcholine (LPC ...