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3951 - 4000 of 10000+ citations for 6 Piperidino 1 purine since 2019

• Arg1⁺ microglia are critical for shaping cognition in female mice

  Vassilis Stratoulias, et al., bioRxiv - Neuroscience 2021

  Quote: ... GFP (1:50, goat, Abcam, ab6673), IΒΑ1 (1:250 ...
• Genetic recombination in disgust-associated bitter taste-responsive neurons of the central nucleus of amygdala in male mice

  Daisuke H. Tanaka, et al., bioRxiv - Neuroscience 2020

  Quote: ... chicken anti-GFP (1:500; abcam), mouse anti-enkephalin (1:400 ...
• Sfrp1 deficiency makes retinal photoreceptors prone to degeneration

  Elsa Cisneros, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-ADAM10 (1:500, Abcam); mouse anti-Rhodopsin K16-155C 74 (kindly provided by Dr ...
• Nicotine exposure and neuronal activity regulate Golgi membrane dispersal and distribution

  Anitha P. Govind, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit St3 pAb (1:300; Abcam) and mouse TH (1:750) ...
• A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell

  Mikha Gabriela, et al., bioRxiv - Microbiology 2021

  Quote: ... chicken anti-FLAG (Abcam,1:2000), mouse anti-FLAG (10 µg/mL) ...
• Alzheimer’s disease-related dysregulation of protein synthesis causes key pathological features with ageing

  Anshua Ghosh, et al., bioRxiv - Neuroscience 2019

  Quote: ... pGSK3β (Tyr216) (Abcam ab75745, 1:300), 4G8 (Calbiochem NE1002 ...
• Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models

  Laura Sebastian Monasor, et al., bioRxiv - Neuroscience 2019

  Quote: ... APP-Y188 (1:2000, ab32136, Abcam), CLEC7a (1:50 ...
• Joint degeneration in a mouse model of pseudoachondroplasia: ER stress, inflammation and autophagy blockage

  Jacqueline T. Hecht, et al., bioRxiv - Pathology 2021

  Quote: ... p16 INK4a - (Abcam; ab189034, 1:200), pS6 (Cell Signaling Technology 2215S rabbit polyclonal ...
• Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosis

  Jennifer A Hollywood, et al., bioRxiv - Physiology 2021

  Quote: ... SQSTM1/p62 (1:1000; 109012 Abcam) and ACTB (1:20,000 ...
• Epidermal TRPV4 ion channels regulate UVB induced sunburn by triggering inflammmasome activation and ERK signaling

  Carlene Moore, et al., bioRxiv - Physiology 2021

  Quote: ... rabbit anti-TRPV4 (1:300; Abcam), goat anti-IL1ß ...
• Leptin receptor expression in the dorsomedial hypothalamus stimulates breathing during NREM sleep in db/db mice

  Huy Pho, et al., bioRxiv - Physiology 2020

  Quote: ... (1:100. ab178846, ABCAM, Cambridge, MA). Then the slides were incubated with goat anti-rabbit secondary antibody ...
• Rapid adaptation of SARS-CoV-2 in BALB/c mice: Novel mouse model for vaccine efficacy

  Hongjing Gu, et al., bioRxiv - Microbiology 2020

  Quote: ... SP-C (Abcam, ab211326, 1:500). After all the antibodies were detected sequentially ...
• TIP60 acetylates H2AZ and regulates doxorubicin-induced DNA damage sensitivity through RAD51 transcription

  Kwok Kin Lee, et al., bioRxiv - Molecular Biology 2020

  Quote: ... AcH2AZ (Abcam, Cat.No. ab18262, 1:2000); H2B (Abcam ...
• ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression

  Xianjiang Lan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... BCL11A (1:1000, Abcam, Cat. #19487), LRF (1:1000 ...
• Activation of pancreatic β-cell genes by multiplex epigenetic CRISPR-editing

  Gimenez Carla Alejandra, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and INS 1:100 (181547, Abcam).
• Serotonergic drugs inhibit CHIKV infection at different stages of the cell entry pathway

  Ellen M. Bouma, et al., bioRxiv - Microbiology 2020

  Quote: ... rabbit-anti-Rab5 (1:1000; Abcam). Secondary HRP-conjugated antibodies ...
• Low dose AKT inhibitor miransertib cures PI3K-related vascular malformations in preclinical models of human disease

  Piotr Kobialka, et al., bioRxiv - Molecular Biology 2021

  Quote: ... vinculin (Abcam, ab49900, diluted 1:10000). The following secondary antibodies from DAKO were used (all diluted 1:5000) ...
• Activated α_IIbβ₃ on platelets mediates flow-dependent NETosis via SLC44A2

  Adela Constantinescu-Bercu, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-SLC44A2 #1 (Abcam; Ab177877) or the first extracellular loop ...
• Activated α_IIbβ₃ on platelets mediates flow-dependent NETosis via SLC44A2

  Adela Constantinescu-Bercu, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-SLC44A2 #1 (Abcam; Ab177877) or rabbit anti-SLC44A2 #2 (LS Bio ...
• A Quantitative Model of Cellular Decision Making in Direct Neuronal Reprogramming

  Adriaan Merlevede, et al., bioRxiv - Systems Biology 2020

  Quote: ... chicken anti-MAP2 (1:10,000, Abcam). Fluorophore-conjugated secondary antibody (Jackson ImmunoResearch Laboratories ...
• Knockdown of astrocytic monocarboxylate transporter 4 (MCT4) in the motor cortex leads to loss of dendritic spines and a deficit in motor learning

  Adam J. Lundquist, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-synaptophysin (1:2000, Abcam, Cambridge ...
• Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2021

  Quote: ... MBP diluted 1:1000 (Abcam, #ab7349), SOX10 diluted 1:100 (Santa Cruz ...
• Loss of the Pioneer Factor FOXA1 Results in Genome-wide Epigenetic Reprogramming and activation of Interferon-Response Genes including CD274/PD-L1

  Wenhuo Hu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... PD-L1 (1:1000, ab213524, abcam), GAPDH (14C10 ...
• Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

  Kerrie-Ann McMahon, et al., bioRxiv - Cancer Biology 2020

  Quote: ... γH2AX alone (1:100, 20669, Abcam) and the appropriate Alexa Fluor™ 488 Goat anti-Rabbit IgG (H+L ...
• HYPERGLYCEMIA-INDUCED MIR-467 DRIVES TUMOR INFLAMMATION AND GROWTH IN BREAST CANCER

  Jasmine Gajeton, et al., bioRxiv - Cancer Biology 2020

  Quote: ... α-actin (clone ab5694 1:200, Abcam), or anti-TSP-1 Ab4 (clone 6.1 1:100 ...
• Activation of the Anaphase Promoting Complex reverses multiple drug resistant cancer

  T.G. Arnason, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HURP (Abcam, 1:1000, 120 kDa), Cyclin B1 (Sigma ...
• Activation of the Anaphase Promoting Complex reverses multiple drug resistant cancer

  T.G. Arnason, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Securin (Abcam, 1:1000, 29 kDa), GAPDH (Abcam ...
• Inhibiting endoplasmic reticulum stress decreases tumor burden in a mouse model for hepatocellular carcinoma

  Natasa Pavlovic, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and EPCAM (1:100; Abcam, ab71916). A 1h incubation was used for the secondary antibody (goat anti-rat Alexa Fluor 555 and Rabbit anti-mouse Alexa Fluor 488) ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... HIF1 alpha (Abcam, ab16066, 1:500). Sections were then incubated with fluorescence-conjugated (FITC ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... total H3 (Abcam, ab1791, 1:10000), DUSP1 (Millipore ...
• Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

  Nina Meyer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... VCP (1:400; Abcam Biochemicals, ab11433), LAMP2 (1:1000 ...
• DDR1-INDUCED NEUTROPHIL EXTRACELLULAR TRAPS DRIVE PANCREATIC CANCER METASTASIS

  Jenying Deng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and CK-19 (1:500; Abcam). The tissue sections were then stained with secondary antibodies conjugated with Alex488 ...
• Topoisomerase 1 dependent R-loop deficiency drives accelerated replication and genomic instability

  Dan Sarni, et al., bioRxiv - Cell Biology 2021

  Quote: ... rabbit anti-TOP1 (Abcam, 1:10,000)) ...
• Stable Flow-induced Expression of KLK10 Inhibits Endothelial Inflammation and Atherosclerosis

  Darian Williams, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-VCAM1 (Abcam ab134047, 1:1000), anti-ICAM1 (Abcam ab53013 ...
• The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult gut

  R. Ramadan, et al., bioRxiv - Cell Biology 2021

  Quote: ... AldolaseB EPR3138Y(1/200, abcam #ab75751), Ly6a-APC (1/200 ...
• ANP32A represses Wnt signaling across tissues tissues thereby protecting against joint and heart disease

  Silvia Monteagudo, et al., bioRxiv - Cell Biology 2021

  Quote: ... ANP32A (Abcam, ab189110; dilution 1:1000), total H3 (Abcam ...
• Mitochondrial energy dysfunction induces remodeling of the cardiac mitochondrial protein acylome

  Jessica N. Peoples, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-Porin (Abcam, ab14734, 1:1000), anti-α-tubulin (Proteintech 11224-1-AP ...
• Proprotein Convertase Subtilisin/kexin Type 9 Links Inflammation to Vascular Endothelial Cell Dysfunction

  Thorsten M. Leucker, et al., bioRxiv - Cell Biology 2021

  Quote: ... VE-Cadherin (ab33168, 1:1000, Abcam), β-actin (ab8226 ...
• Moving patronin foci and growing microtubule plus ends direct the spatiotemporal dynamics of Rho signaling and myosin during apical constriction

  Anwesha Guru, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-EB1 (rat 1:200, Abcam), pMLC Ser19 (rabbit 1:50 ...
• Moving patronin foci and growing microtubule plus ends direct the spatiotemporal dynamics of Rho signaling and myosin during apical constriction

  Anwesha Guru, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-RFP (mouse 1:1000, Abcam), anti-ECadherin (rat 1:10 ...
• Human induced pluripotent stem cell-derived three-dimensional cardiomyocyte tissues ameliorate the rat ischemic myocardium by remodeling the extracellular matrix and cardiac protein phenotype

  Junya Yokoyama, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-collagen IV (1:100; Abcam), anti-heparan sulfate proteoglycan 2 (1:100 ...
• Human induced pluripotent stem cell-derived three-dimensional cardiomyocyte tissues ameliorate the rat ischemic myocardium by remodeling the extracellular matrix and cardiac protein phenotype

  Junya Yokoyama, et al., bioRxiv - Cell Biology 2021

  Quote: ... and anti-dystrophin (1:50; Abcam), followed by incubation with the secondary antibodies AlexaFluor488- or AlexaFluor555-conjugated goat or donkey anti-mouse or anti-rabbit (ThermoFisher Scientific) ...
• Cells protect chromosome-microtubule attachments, independent of biorientation, using an Astrin-PP1 and CyclinB-CDK1 feedback loop

  Duccio Conti, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cyclin B1 (Abcam; ab72; 1:1000), GFP (Roche ...
• The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency

  Kazutoshi Takahashi, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-SOX2 (1:100, ab97959, Abcam), anti-NANOG (1:100 ...
• The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency

  Kazutoshi Takahashi, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-NANOG (1:100, ab21624, Abcam), anti-KLF17 (1:100 ...
• Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

  Angela Duong, et al., bioRxiv - Neuroscience 2020

  Quote: ... UQCRC1 (mouse, abcam, ab110252, 1:50), COXIV (mouse ...
• Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

  Angela Duong, et al., bioRxiv - Neuroscience 2020

  Quote: ... SDHA (mouse, abcam, ab14715, 1:200), UQCRC1 (mouse ...
• Characterization of mitochondrial health from human peripheral blood mononuclear cells to cerebral organoids derived from induced pluripotent stem cells

  Angela Duong, et al., bioRxiv - Neuroscience 2020

  Quote: ... COXIV (mouse, abcam, ab33985, 1:200), ATP Synthase β (mouse ...
• Differentiation of ciliated human midbrain-derived LUHMES neurons

  Gilbert Lauter, et al., bioRxiv - Neuroscience 2020

  Quote: ... KIF17 (rabbit, Abcam ab11261, 1:2000), TH (rabbit ...
• Increased p53 signaling impairs neural differentiation causing HUWE1-promoted intellectual disabilities

  Rossana Aprigliano, et al., bioRxiv - Cell Biology 2020

  Quote: ... Ki67 (diluted 1:200, Abcam ab15580) diluted in 0.5% BSA ...