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3001 - 3050 of 10000+ citations for 6 Piperidino 1 purine since 2019

• Discovery and Validation of Novel LonP1 and Proteasome Inhibitor in IDH1-R132H Malignant Astrocytoma Models

  Christopher Douglas, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:1000 Aconitase2 (Abcam, ab71440), 1:1000 LC3B (Cell Signaling Technology ...
• Development of an Accelerated Cellular Model for Alzheimer’s Disease

  Huijing Xue, et al., bioRxiv - Cell Biology 2023

  Quote: ... γ-H2AX antibody (Abcam, 1:3000), and β-actin (1:5000 ...
• CRISPRi Gene Modulation and All-Optical Electrophysiology in Post-Differentiated Human iPSC-Cardiomyocytes

  Julie L. Han, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1:1000 ab181602 GAPDH (Abcam)) ...
• PRMT1 Inhibition Selectively Targets BNC1-Dependent Proliferation, but not Migration in Squamous Cell Carcinoma

  Rafik Boudra, et al., bioRxiv - Cancer Biology 2023

  Quote: ... SPRR1B (Abcam, ab176322, 1:1000), FILAGGRIN (Abcam ...
• Development of an Accelerated Cellular Model for Alzheimer’s Disease

  Huijing Xue, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-tubIII antibody (Abcam, 1:1000); GFAP antibody (Cell Signaling ...
• Metabolic benefits of 17α-estradiol in liver are partially mediated by ERβ in male mice

  Samim Ali Mondal, et al., bioRxiv - Physiology 2023

  Quote: ... and GAPDH (Abcam; 1:50).
• The vascularised chamber device significantly enhances the survival of transplanted liver organoids

  Denis D. Shi, et al., bioRxiv - Bioengineering 2023

  Quote: ... Sox9 (Abcam, ab185966, 1:1000), human albumin (Bethyl Laboratories ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... P53 (ab33889, 1:200, Abcam), Aggrecan (Acan ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... ADANTS5 (ab41037, 1:1000, Abcam), MMP13(ab39012 ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... MMP13(ab39012, 1:1000, Abcam). β-actin (1:1000 ...
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... ACSL4 (ab155282, 1:1000, Abcam), P53 (ab33889 ...
• RAD52 prevents accumulation of Polα-dependent replication gaps at perturbed replication forks in human cells

  Ludovica Di Biagi, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-RAD51 (Abcam 1:10,000), anti-SMARCAL1 (Bethyl 1:1500) ...
• Piezo1 activates non-canonical EGFR endocytosis and signaling

  Carlos Pardo-Pastor, Jody Rosenblatt, bioRxiv - Cell Biology 2023

  Quote: ... Ki67 (1/100, Abcam, ab16667).
• Liproxstatin-1 alleviates cartilage degradation by inhibiting chondrocyte ferroptosis in temporomandibular joint

  Bei Cheng, et al., bioRxiv - Cell Biology 2023

  Quote: ... P53 (ab33889, 1:1000, Abcam), Aggrecan (Acan ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... H3K4me1 (1:2500, ab889 Abcam), H3K4me2 (1:2500 ...
• The BOD1L subunit of the mammalian SETD1A complex sustains the expression of DNA damage repair genes despite restraining H3K4 trimethylation

  Giovanni Ciotta, et al., bioRxiv - Cell Biology 2023

  Quote: ... H3K4me2 (1:2500, ab7766 Abcam), H3K4me3 (1:1000 ...
• N6-methyladenosine demethylase FTO serves as an indicator for predicting prognosis and immunotherapy response in individuals with gastric cancer

  Shiheng Jia, et al., bioRxiv - Cancer Biology 2023

  Quote: ... FTO (1:1000; ab12660; Abcam), PDL1 (1:1000 ...
• N6-methyladenosine demethylase FTO serves as an indicator for predicting prognosis and immunotherapy response in individuals with gastric cancer

  Shiheng Jia, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GAPDH (1:1000; ab8245; Abcam) were purchased and used in this study ...
• FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer

  Shruti Menon, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 53BP1(Abcam, ab17593, 1:1000), pATM (CST ...
• Stretch-injury promotes activation of microglia with enhanced phagocytic and synaptic stripping activities

  Anthony Procès, et al., bioRxiv - Biophysics 2023

  Quote: ... GFP (Abcam, Ab13970, 1:2,000).
• N6-methyladenosine demethylase FTO serves as an indicator for predicting prognosis and immunotherapy response in individuals with gastric cancer

  Shiheng Jia, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PDL1 (1:1000; ab205921; Abcam), GAPDH (1:1000 ...
• SKP2 knockout in Rb1/p53 deficient mouse models of osteosarcoma induces immune infiltration and drives a transcriptional program with a favorable prognosis

  Alexander Ferrena, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or Iba-1 (Abcam, #ab178846) antibodies at 4℃ overnight ...
• Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodelling

  Sara F.F. Almeida, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ITGα6 (1:1000, ab181551, Abcam) and CD44/HCAM (1:200,sc-7297 ...
• Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodelling

  Sara F.F. Almeida, et al., bioRxiv - Cancer Biology 2023

  Quote: ... EFEMP1 (1:1000, ab256457, Abcam), ITG Β1 (1:1000 ...
• The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

  Ling Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p16INK4a (1:1,000, Abcam, ab108349), TRX1 (1:1,000 ...
• The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

  Ling Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GAPDH (1:10,000, Abcam, ab9485), cleaved-PARP (1:1,000 ...
• The soluble guanylyl cyclase pathway is inhibited to evade androgen deprivation-induced senescence and enable progression to castration resistance

  Ling Zhang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... β-actin (1:5,000, Abcam, ab8226), actin (1:2,500 ...
• PRMT1 is a critical dependency in clear cell renal cell carcinoma through its role in post-transcriptional regulation of DNA damage response genes

  Joseph Walton, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CAS9 (Abcam, #ab191468, 1:1000), FLAG (Sigma ...
• PRMT1 is a critical dependency in clear cell renal cell carcinoma through its role in post-transcriptional regulation of DNA damage response genes

  Joseph Walton, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Actin (Abcam #ab7817, 1:1000), BRCA2 (CST ...
• Fluorescein-based sensors to purify human α-cells for functional and transcriptomic analyses

  Sevim Kahraman, et al., bioRxiv - Cell Biology 2022

  Quote: ... DLK1 (Abcam, ab21682, 1:1,000), GSN (Sigma ...
• RNA-binding protein YBX1 promotes Type H vessels dependent bone formation in an m5C-dependent manner

  Yu-Jue Li, Qi Guo, Wen-Feng Xiao, Ye Xiao, bioRxiv - Molecular Biology 2023

  Quote: ... Osterix (#ab22552, abcam, 1:200), and Bmp4 (#30912 ...
• Early and late chaperone intervention therapy boosts XBP1s and ADAM10, restores proteostasis, and rescues learning in Alzheimer’s Disease mice

  Jennifer M. Hafycz, et al., bioRxiv - Neuroscience 2023

  Quote: ... BDNF (1:500, Abcam ab108319); β-Actin (1:2000 ...
• Increased hyaluronan by naked mole-rat HAS2 extends lifespan in mice

  Zhihui Zhang, et al., bioRxiv - Physiology 2023

  Quote: ... Anti-Lyzozyme (1:500, Abcam). Following the primary antibody incubation ...
• Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

  Aitor Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: ... Tubulin (Abcam, ab18251, 1:5000). Rat anti-Calnexin (clone W17077C ...
• Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses

  Yanis Inglebert, et al., bioRxiv - Neuroscience 2023

  Quote: ... GluN2A (1:1800, Abcam, ab124913,), GluN2B (1:1800 ...
• Overexpressed Malat1 Drives Metastasis through Inflammatory Reprogramming of Lung Adenocarcinoma Microenvironment

  Elena Martinez-Terroba, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cd68 (Abcam, ab125212; 1:100), Ki67 (D3B5 ...
• Srcap Haploinsufficiency Induced Autistic-Like Behaviors in Mice through Disruption of Satb2 Expression

  Chaodong Ding, et al., bioRxiv - Neuroscience 2023

  Quote: ... VIP (1:500, Abcam, 63269), Olig2 (1:500 ...
• The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria and tyrosinemia type 1

  Peter D. Szigetvari, et al., bioRxiv - Molecular Biology 2023

  Quote: ... BCAT2 (#95976, Abcam; 1:1000), GAPDH (#sc-32233 Santa Cruz Biotech ...
• The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria and tyrosinemia type 1

  Peter D. Szigetvari, et al., bioRxiv - Molecular Biology 2023

  Quote: ... DHFR (#133546, Abcam; 1:1000), QDPR (#186411 ...
• Multiplexing cortical brain organoids for the longitudinal dissection of developmental traits at single cell resolution

  Nicolò Caporale, et al., bioRxiv - Neuroscience 2023

  Quote: ... SATB2 (Mouse, 1:400, Abcam), HOPX (Rabbit ...
• Rapamycin mitigates Valproic Acid-induced teratogenicity in human and animal models by suppressing AP-1-mediated senescence

  Giovanni Pietrogrande, et al., bioRxiv - Neuroscience 2023

  Quote: ... OP (ab8448, ABCam 1:1000), FABP4 (ab92501 ...
• Loss of Wdr23 drives neuronal mitochondrial biogenesis

  Ronald Irwin, et al., bioRxiv - Molecular Biology 2023

  Quote: ... TIMM17A/TIM17 (Abcam, 1:1000), VDAC1/porin+VDAC2 (Abcam ...
• NUDC is critical for rod photoreceptor function, maintenance, and survival

  Mary Anne Garner, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-transducin (Abcam, 1:2000); anti-LIS1 (CST ...
• Attenuating amyloid-beta pathology in mice with in situ programmed astrocytes

  Lun Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Synaptophysin (Abcam, #ab32127, 1:1000), APOE (Beyotime ...
• Attenuating amyloid-beta pathology in mice with in situ programmed astrocytes

  Lun Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Synaptophysin (Abcam, #ab32127, 1:100).
• Attenuating amyloid-beta pathology in mice with in situ programmed astrocytes

  Lun Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... PSD95 (Abcam, #ab12093, 1:1000), Synaptophysin (Abcam ...
• Attenuating amyloid-beta pathology in mice with in situ programmed astrocytes

  Lun Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... LAMP1 (Abcam, #ab24170, 1:100), Iba-1 (GeneTex ...
• Attenuating amyloid-beta pathology in mice with in situ programmed astrocytes

  Lun Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... P2ry12 (Abcam, #ab188968, 1:500), PSD95 (Abcam ...
• Structural basis of epitope recognition by anti-alpha synuclein antibodies MJFR14-6-4-2

  Ilva Liekniņa, et al., bioRxiv - Neuroscience 2023

  Quote: ... tubulin (Abcam #ab6160, 1:1000), total-⍺-Syn (Abcam #ab27766 ...
• Placode and neural crest origins of congenital deafness in mouse models of Waardenburg-Shah syndrome

  Jamie Vicente S. Tan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Peripherin (1:200; Abcam ab99942), SYP (1:500 ...