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251 - 300 of 1379 citations for Ethyl 7 oxo 7 2 thiomorpholinomethyl phenyl heptanoate since 2020

• The establishment of HP1-independent heterochromatin reveals an essential role for HP1 proteins in maintaining epigenetic memory

  Melissa Seman, et al., bioRxiv - Genetics 2023

  Quote: ... 2 µg H3K9me2 antibody (Abcam, ab1220), 2µg H3K9me3 antibody (39161 ...
• ATRX guards against aberrant differentiation in mesenchymal progenitor cells

  Yan Fang, et al., bioRxiv - Genetics 2023

  Quote: ... 2 µg ATRX antibody (Abcam, ab97508) was added ...
• Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

  Ester Gil Vazquez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... (2) CD34 (1:3000, ab81289; Abcam)–Opal 520 ...
• Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture

  Ester Gil Vazquez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... (2) CD4 (1:500, ab183685; Abcam)–Opal 520 ...
• Microtubule reorganization during mitotic cell division in the dinoflagellate Ostreospis cf. ovata

  David Velasquez-Carvajal, et al., bioRxiv - Cell Biology 2023

  Quote: ... YL1/2 antibody (ab6160; rat, Abcam) was used at 1:400 dilution ...
• Helicobacter pylori cancer associated CagA protein drives intestinal metaplastic transition in human gastric organoids

  Mar Reines, et al., bioRxiv - Cell Biology 2023

  Quote: ... Claudin-2 (Abcam Cat. No. ab53032), β-Actin (Sigma ...
• Induction of apoptosis by double-stranded RNA was present in the last common ancestor of cnidarian and bilaterian animals

  Itamar Kozlovski, et al., bioRxiv - Evolutionary Biology 2023

  Quote: ... 2 mM cycloheximide (Abcam, United Kingdom), or an equivalent concentration of DMSO in 24-well plate containing 500 µL N ...
• Extracellular RNA induce neutrophil recruitment via endothelial TLR3 during venous thrombosis after vascular injury

  Maria Y. Najem, et al., bioRxiv - Physiology 2024

  Quote: ... a rat anti-MOMA-2 (Abcam) and rabbit anti-mouse CitH3 (Abcam ...
• ENDOTHELIAL GENE REGULATORY ELEMENTS ASSOCIATED WITH CARDIOPHARYNGEAL LINEAGE DIFFERENTIATION

  Ilaria Aurigemma, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and 2 μM Forskolin (Abcam, ab120058). The Induction Medium was changed after one day ...
• Awakening adult neural stem cells: NOX signalling as a positive regulator of quiescence to proliferation transition in the Xenopus retina

  A. Donval, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and rotenone (ROT, 2 mM; Abcam) stock solutions were systematically made freshly following reconstitution in DMSO ...
• Innate immune receptor C5aR1 regulates cancer cell fate and can be targeted to improve radiotherapy in tumours with immunosuppressive microenvironments

  Callum Beach, et al., bioRxiv - Cancer Biology 2023

  Quote: ... (2) CD34 (1:3000, ab81289; Abcam)–Opal 520 ...
• Endocytosis is regulated through the pH-dependent phosphorylation of Rab GTPases by Parkinson’s kinase LRRK2

  Michelle E. Maxson, et al., bioRxiv - Cell Biology 2023

  Quote: ... MLi-2 was purchased from Abcam. Fluorescent conjugated 10 kDa dextrans were purchased from Invitrogen ...
• MicroRNA-22, Specificity protein-1 and Cystathionine β-synthase in early onset Preeclampsia: significance in trophoblast invasion

  Pallavi Arora, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Primary antibodies to MMP-2 (Abcam) at a dilution of 1:500 ...
• Short term effect of tetrahydrocurcumin on adipose angiogenesis in very high-fat diet-induced obesity mouse model

  Bhornprom Yoysungnoen, et al., bioRxiv - Physiology 2023

  Quote: ... MMP-2 (1:500; ab86607, Abcam), MMP-9 (1:500 ...
• Growth factor-free, peptide-functionalized gelatin hydrogel promotes arteriogenesis and attenuates tissue damage in a murine model of critical limb ischemia

  Corinne W. Curry, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 2) CD31 (1:100; Abcam) and α-SMA ...
• LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes

  Jin Li, et al., bioRxiv - Cell Biology 2024

  Quote: ... Aconitase 2 (1:1000, Abcam, ab110321), Anti-NDUFA10 (1:1000 ...
• ACTN3 genotype influences androgen response in skeletal muscle

  Kelly N. Roeszler, et al., bioRxiv - Genetics 2024

  Quote: ... α-actinin-2 (ab68204, ab68167, abcam), Akt1 (#C73H10 ...
• The ER Thioredoxin-Related Transmembrane Protein TMX2 Controls Redox-Mediated Tethering of ER-Mitochondria Contacts (ERMCS)

  Junsheng Chen, et al., bioRxiv - Cell Biology 2024

  Quote: ... 2 µg/mL oligomycin (141829, Abcam) was added to inhibit ATP synthase and estimate the leak respiration ...
• Identification of Ephrin type-B receptor 4 as a critical mediator of tissue fibrosis

  Brian Wu, et al., bioRxiv - Pathology 2024

  Quote: ... SMAD 2/3 (Abcam, catalog #ab217553), and GAPDH (Abcam ...
• Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein

  Rui Tong Quek, et al., bioRxiv - Molecular Biology 2024

  Quote: ... + 2% normal goat serum (Abcam ab7481) at room temperature for 1h ...
• Structure of the Flotillin Complex in a Native Membrane Environment

  Ziao Fu, Roderick MacKinnon, bioRxiv - Biochemistry 2024

  Quote: ... Stomatin-like protein 2 (Abcam, ab191883) and detected using fluorescence.
• Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)

  Ting Zhang, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... 2 μg H3K9me3 antibody (ab8898; Abcam), 2 μg CEBPB antibody (PA5-27244 ...
• Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations

  Rohan Bhattacharya, et al., bioRxiv - Bioengineering 2024

  Quote: ... 2 µM forskolin (Abcam Inc., ab120058), and 200 ng/mL VEGF165 ...
• Tenascin-C potentiates Wnt signaling in thyroid cancer

  Heather A. Hartmann, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Rabbit Anti-Wnt-2 (Abcam, ab1009222), Rabbit anti-V5 (Cell Signaling ...
• PLK-1 regulates MEX-1 polarization in the C. elegans zygote

  Amelia J. Kim, et al., bioRxiv - Developmental Biology 2024

  Quote: ... containing 2 mM ATP-γS (Abcam) and 375 ng of hPLK1 (EMD Millipore) ...
• Adhesion-Controlled Mechanics of the Glial Niche Regulate Neural Stem Cell Proliferative Potential

  Anna Segú Cristina, et al., bioRxiv - Developmental Biology 2024

  Quote: ... 2% Normal Goat Serum (Abcam ab7481)) for 1 hour at room temperature while rocking ...
• DNA Methylation Patterns Expose Variations in Enhancer-Chromatin Modifications during Embryonic Stem Cell Differentiation

  Adi Alajem, et al., bioRxiv - Molecular Biology 2020

  Quote: Antibodies (H3K4me1 abcam ab8895, H3K27Ac abcam ab4729, H3K36me abcam ab9050, 2 μg antibody per 2×107 cells) were incubated with 25 μL protein A Dynabeads (Thermo Scientific ...
• Borrowing Transcriptional Kinases to Activate Apoptosis

  Roman Sarott, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 50 µg of chromatin was used with anti-Pol II ser 2 phos (2 µg, Abcam ab5095) and anti-Pol II ser 5 phos (2 µg ...
• Esrrb is a cell cycle dependent XEN priming factor balancing between pluripotency and differentiation

  Sapir Herchcovici Levi, et al., bioRxiv - Molecular Biology 2021

  Quote: ChIP Antibodies (H3K4me1 abcam ab8895, H3K27Ac abcam ab4729, H3K36me abcam ab9050, 2 µg antibody per 2×107 cells) were incubated with 25 µL protein A Dynabeads (Thermo Scientific ...
• DDHD2 provides a critical flux of saturated fatty acids to support neuronal energy demands

  Saber H. Saber, et al., bioRxiv - Neuroscience 2024

  Quote: ... Neurons were then immunostained against endogenous AP-2 using Anti-AP-2 complex subunit alpha-1 (Abcam, #ab218624) diluted in blocking solution (1% BSA in PBS ...
• Gain-of-function mutations amplify cytotoxic FAM111 protease activity in human genetic disorders

  Saskia Hoffmann, et al., bioRxiv - Cell Biology 2020

  Quote: ... and RFC1 (ab3566, Abcam, 2 μg/IP). Antibodies used for immunofluorescence included ...
• Fate tracing reveals differences between Reelin⁺ HSCs and Desmin⁺ HSCs in activation, migration, and proliferation activities

  Ning Chen, et al., bioRxiv - Pathology 2022

  Quote: ... 6-diamidino-2-phenylindole (DAPI) (Abcam, ab104139). Images were acquired with a laser scanning confocal microscope (Carl Zeiss Microscopy ...
• A concurrent canonical and modified miRNAome pan-cancer study on TCGA and TARGET cohorts leads to an enhanced resolution in cancer

  Rosario Distefano, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Anti- AGO-2 (Novus) and Vinculin (Abcam) antibodies were used for western blotting analysis.
• Mouse CHD4-NURD is required for neonatal spermatogonia survival and normal gonad development

  Rodrigo O. de Castro, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-CHD4 (2 μg, Abcam ab72418), or rabbit IgG (5μg Jackson ImmunoResearch ...
• Environmentally-induced mdig is a major contributor to the severity of COVID-19 through fostering expression of SARS-CoV-2 receptor NRPs and glycan metabolism

  Qian Zhang, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-SARS-CoV-2-Spike (Abcam, ab272504), anti-Furin (Abcam ...
• Dietary Vitamin B₁₂ reduces amyloid-β proteotoxicity by alleviating oxidative stress and mitochondrial dysfunction

  Andy B. Lam, Kirsten Kervin, Jessica E. Tanis, bioRxiv - Cell Biology 2021

  Quote: ... NUO-2 (Abcam cat#ab14711, 1:5000), α-tubulin (Sigma cat#T9026 ...
• A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation

  Yoshifumi Sonobe, et al., bioRxiv - Neuroscience 2020

  Quote: ... or tubulin (1:5000, YL1/2, Abcam). Following washing ...
• Cetuximab produced from a goat mammary gland expression system is equally efficacious as innovator cetuximab in model systems of cancer

  Qian Wang, et al., bioRxiv - Bioengineering 2020

  Quote: ... 2 equivalents of Cy5-maleimide (Abcam ab146489) was added and incubated 30 min at room temperature ...
• Pharmacodynamic Markers of LRRK2 Inhibition in Biofluids

  Shijie Wang, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-LRRK2 (clone MJFF2 c41-2, Abcam), anti-pS935 LRRK2 (clone UDD2-10 ...
• Ultrasound-mediated mechanical forces selectively kill tumor cells

  Ajay Tijore, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Calpain 2 (rabbit, 1:1000, Abcam, ab39165), Piezo1 (rabbit ...
• Bromodomain factor 5 is an essential transcriptional regulator of the Leishmania genome

  Nathaniel G. Jones, et al., bioRxiv - Cell Biology 2021

  Quote: ... 2 μl (500 Units) BaseMuncher Endonuclease (Abcam). The lysate was sonicated 3 × 10 seconds at 40% amplitude using a probe sonicator (Sonics Vibra-Cell ...
• Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes

  Charlene Lancaster, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 5 µM dynole 34-2 (Abcam). For clathrin inhibitors ...
• Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

  Vasiliki-Ilya Gargareta, et al., bioRxiv - Neuroscience 2022

  Quote: ... sirtuin 2 (SIRT2, Abcam #ab67299, 1:500), immunoglobulin superfamily member 8 (IGSF8 ...
• Reconstructing cell interactions and state trajectories in pancreatic cancer stromal tumoroids

  Ryo Okuda, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Lipocalin-2 (1:100, Abcam, ab23477), anti-E-cadherin (1:100 ...
• Expansion of Ventral Foregut Primes the Enhancer Landscape for Organ Specific Differentiation

  Yan Fung Wong, et al., bioRxiv - Developmental Biology 2022

  Quote: ... and 2 µg of H3K27ac (Abcam, ab4279). Immunoprecipitation and washes were done as described in the True MicroChIP protocol ...
• Mer3 helicase protects early crossover intermediates from STR complex disassembly during meiosis

  Veronika Altmannova, et al., bioRxiv - Biochemistry 2022

  Quote: ... Anti-Strep antibody (2 μL, Abcam, ab76949) was added to the reactions and the mixtures were incubated for 1 hour at 4°C in the thermomixer (950 rpm) ...
• Endogenous Rab38 regulates LRRK2’s membrane recruitment and substrate Rab phosphorylation in melanocytes

  Alexandra Unapanta, et al., bioRxiv - Cell Biology 2022

  Quote: ... rabbit anti-LRRK2 C41-2 (Abcam, ab133474), rabbit anti-LRRK2 phospho S1292 (Abcam ...
• The role of Cycloastragenol at the intersection of Nrf-2/ARE, telomerase, and proteasome activity

  Sinem Yılmaz, et al., bioRxiv - Cell Biology 2022

  Quote: ... Antibodies against Nrf-2 (Abcam, Ab-62352), Nrf-2 (Bioss ...
• Activity-dependent tuning of intrinsic excitability in mouse and human neurogliaform cells

  R. Chittajallu, et al., bioRxiv - Neuroscience 2020

  Quote: ... 2-5μM CGP556845A (Abcam; Cat. No. ab120337), 5-10μM bicuculline methobromide (Abcam ...
• A noble TGFβ biogenesis inhibitor exhibits both potent anti-fibrotic and anti-inflammatory capabilities

  Han-Soo Kim, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... or 1:500 anti- MD-2 (Abcam) antibodies and 1:200 FITC conjugated secondary antibody (Young In Frontier ...