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1851 - 1900 of 10000+ citations for Flap endonuclease 1 FEN 1 Human since 2019

• Intermittent hypoxia enhances the expression of HIF1A by increasing the quantity and catalytic activity of KDM4A-C and demethylating H3K9me3 at the HIF1A locus

  Chloe-Anne Martinez, et al., bioRxiv - Cell Biology 2021

  Quote: ... Glut1 (ab115730, 1:1000, Abcam), LDHA (3582T ...
• Intermittent hypoxia enhances the expression of HIF1A by increasing the quantity and catalytic activity of KDM4A-C and demethylating H3K9me3 at the HIF1A locus

  Chloe-Anne Martinez, et al., bioRxiv - Cell Biology 2021

  Quote: ... JMJD2C (ab226480, 1:500, Abcam), Tri- Methyl-Histone H3 (Lys9 ...
• Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

  Samantha L. Bell, et al., bioRxiv - Microbiology 2020

  Quote: ... Alix (Abcam, ab117600; 1:2500), and syntenin-1 (Abcam ...
• Memory destabilization and reconsolidation dynamically regulate the PKMζ maintenance mechanism

  Matteo Bernabo, Karim Nader, bioRxiv - Neuroscience 2020

  Quote: ... 1:10,000 GAPDH (Abcam, ab8245). Following overnight incubation ...
• Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement

  Ashley L. Kalinski, et al., bioRxiv - Neuroscience 2020

  Quote: ... α-CD11b (1:1000, Abcam, ab133357), α-ERK1/2 (1:5000 ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... -S100β (1:100; Abcam, ab868) –TUBB3 (1:300 ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... S100β (1:100; Abcam, ab868). The secondary antibodies used are detailed above ...
• Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice

  Gema M. Olivarria, et al., bioRxiv - Microbiology 2021

  Quote: ... MHC I (1:200 Abcam), and MHC II (1:200 Abcam) ...
• Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

  Laura J. Wagstaff, et al., bioRxiv - Neuroscience 2020

  Quote: ... Neurofilament (Abcam, rabbit 1:1000) donkey anti-goat IgG (H+L ...
• Lis1 mutation prevents basal radial glia-like cell production in the mouse

  Maxime Penisson, et al., bioRxiv - Neuroscience 2020

  Quote: ... Tbr2 (AB23345, Abcam, 1:300), Tbr1 (grateful gift from Robert Hevner ...
• Amyloid plaque deposition accelerates tau propagation via activation of microglia in a humanized APP mouse model

  Kevin A. Clayton, et al., bioRxiv - Neuroscience 2020

  Quote: ... C1Q 1:300 (Abcam #ab182451), 82E1 1:100 (IBL #10323) ...
• Retromer Combinatorials for Gene-Therapy Across a Spectrum of Neurological Diseases

  Yasir H. Qureshi, et al., bioRxiv - Neuroscience 2020

  Quote: ... VPS26a (ab211530, Abcam, 1:500), VPS26b (NBP1-92575 ...
• Retromer Combinatorials for Gene-Therapy Across a Spectrum of Neurological Diseases

  Yasir H. Qureshi, et al., bioRxiv - Neuroscience 2020

  Quote: ... VPS35 (ab57632, Abcam, 1:1k), VPS26a (ab211530 ...
• EWSR1 affects PRDM9-dependent histone 3 methylation and provides a link between recombination hotspots and the chromosome axis

  Hui Tian, et al., bioRxiv - Developmental Biology 2020

  Quote: ... γH2AX (1:1000, Abcam, ab26350), BRCA1 (1:200 ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... Sox9 (Abcam, ab185230, 1:500); Sox2 (CST ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... Furin (Abcam, ab108209, 1:400); Tmprss2 (Abcam ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... Tmprss2 (Abcam, ab92323, 1:500); CD3 (CST ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... CD103 (Abcam, ab224202, 1:300); Ly-6G (CST ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... OMP (Abcam, ab183947, 1:1500); CK5 (Abcam ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... CK5 (Abcam, ab52635, 1:800); CK8 (Abcam ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... GAP43 (Abcam, ab75810, 1:1000); OMP (Abcam ...
• SARS-CoV-2 infection causes transient olfactory dysfunction in mice

  Qing Ye, et al., bioRxiv - Microbiology 2020

  Quote: ... CK8 (Abcam, ab53280, 1:800); Sox9 (Abcam ...
• Astrocyte-secreted glypican-4 drives APOE4-dependent tau pathology

  Sivaprakasam R. Saroja, et al., bioRxiv - Neuroscience 2021

  Quote: ... MAP2 (1:500, #ab5392, abcam), LRP1 (1:200 ...
• Adult mouse retina explants: an ex vivo window to explore central nervous system diseases

  Julia Schaeffer, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti GFP (AbCAM, 1:500)) in blocking solution (BSA (Sigma Aldrich ...
• Spike mutation T403R allows bat coronavirus RaTG13 to use human ACE2

  Fabian Zech, et al., bioRxiv - Microbiology 2021

  Quote: ... ACE2 (1:1,000, Abcam, #GTX632604), VSV-M (1:2,000 ...
• A lamin A/C variant causing striated muscle disease provides insights into filament organization

  Rafael Kronenberg-Tenga, et al., bioRxiv - Cell Biology 2020

  Quote: ... H3K27ac (Abcam, ab4729, 1:350). After a 3x 5min wash in PBST ...
• Histone H4K20 methylation synchronizes cytoskeletal dynamics with cell cycle phases during epidermal differentiation

  Alessandro Angerilli, et al., bioRxiv - Developmental Biology 2020

  Quote: ... H4K20me3 1:1000 (Abcam Ab9053), panH3 1:10000 (Abcam Ab1791) ...
• Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium and age-associated mitochondrial dysfunction

  Mohammad Faujul Kabir, et al., bioRxiv - Molecular Biology 2021

  Quote: ... ATP1B3 (Abcam, ab137055; 1:100) and CNFN (Novus Biologicals ...
• Activation of pancreatic β-cell genes by multiplex epigenetic CRISPR-editing

  Gimenez Carla Alejandra, et al., bioRxiv - Molecular Biology 2020

  Quote: ... PAX4 1:100 (AV32064, Abcam) and INS 1:100 (181547 ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MAP2 (Abcam, #ab183830. 1:200), PAX6 (Abcam ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SOX1 (Abcam, #ab109290. 1:200), SOX9 (Cell Signaling Technology ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SOX1 (Abcam, #ab109290, 1:200), SRSF3 (Abcam ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PAX6 (Abcam, #ab195045. 1:200), SETDB1 (Cell Signaling Technology ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SRSF3 (Abcam, #ab198291. 1:1,000), SYN1 (Cell Signaling Technology ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... ZIC1 (Abcam, #ab134951. 1:1,000).
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SRSF3 (Abcam, #ab198291. 1:200), SYN1(Cell Signaling Technology ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... SF3B1 (Abcam, #ab172634. 1:200), SOX1 (Abcam ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... MAP2 (Abcam, #ab183830. 1:200), MSI1 (Cell Signaling Technology ...
• Neural stemness unifies cell tumorigenicity and pluripotent differentiation potential

  Min Zhang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... H3K9me3 (Abcam, #ab8898. 1:1,000), HA-tag (Cell Signaling Technology ...
• Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions

  Jacob T. Boyd, et al., bioRxiv - Neuroscience 2020

  Quote: ... ATF3 (1:400; ab207434, Abcam), NeuN (1:500 ...
• Modeling alcoholic liver disease in a human Liver-Chip

  Janna C. Nawroth, et al., bioRxiv - Bioengineering 2020

  Quote: ... anti-Vimentin (1:50, Abcam), and anti-smooth muscle actin (anti-αSMA ...
• Divide et Impera: Identification of Small-Molecule Inhibitors of HCMV Replication Interfering with Dimerization of DNA Polymerase Processivity Factor UL44

  Hanieh Ghassabian, et al., bioRxiv - Microbiology 2020

  Quote: ... α-pp28 (Abcam, #ab6502; 1:10,000), rabbit α-GADPH pAb (Santa Cruz Biotech ...
• Loss of the Pioneer Factor FOXA1 Results in Genome-wide Epigenetic Reprogramming and activation of Interferon-Response Genes including CD274/PD-L1

  Wenhuo Hu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... FOXA1 (1:500, ab23738, Abcam), PD-L1 (1:1000 ...
• Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

  Kerrie-Ann McMahon, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and Tubulin (1:5000, Abcam). For knockdown experiments of cavin3 and BRCA1 ...
• Alternative Cdc20 translational isoforms bypass the spindle assembly checkpoint to control mitotic arrest duration

  Mary Jane Tsang, Iain M. Cheeseman, bioRxiv - Cell Biology 2021

  Quote: ... Bub1 (1:200, Abcam, ab54893). Images were acquired on a DeltaVision Core deconvolution microscope (Applied Precision ...
• Wilms Tumorigenesis in Human Kidney Organoids

  Verena Waehle, et al., bioRxiv - Cancer Biology 2021

  Quote: ... WT1 (Abcam #ab89901; 1:200); donkey-anti-rabbit AF 488 (Thermo Fisher #A-21206 ...
• HDAC3 regulates senescence and lineage specificity in non-small cell lung cancer

  Lillian J. Eichner, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Nkx2-1 was from Abcam ab76013 and was diluted 1:1,500 ...
• The CoREST Repressor Complex Mediates Phenotype Switching and Therapy Resistance in Melanoma

  Muzhou Wu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... DUSP5 (Abcam, ab200708, 1:1000), Phospho-c-Jun (Ser63 ...
• Tumor genotype dictates radiosensitization after Atm deletion in brainstem gliomas

  Katherine M. Deland, et al., bioRxiv - Cancer Biology 2020

  Quote: ... NQO1 (Abcam, ab34173, 1:1,000), Actin (BD Transduction ...
• The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

  Carlos Gomez-Diaz, et al., bioRxiv - Cell Biology 2021

  Quote: ... Ly6G (Abcam, ab2557, 1:500), CD3 (Abcam ab49943 ...