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1051 - 1100 of 4023 citations for 6 CHLORO 2 METHYL 3 4' BIPYRIDINE 5 CARBONITRILE since 2019

• Prior hypoxia exposure enhances murine microglial inflammatory gene expression in vitro without concomitant H3K4me3 enrichment

  Elizabeth A. Kiernan, et al., bioRxiv - Neuroscience 2020

  Quote: ... vehicle (DMSO) or 3 µM BOT-64 (Abcam; Cambridge, MA) was added prior to the start of Hx ...
• A Strategy to Quantify Myofibroblast Activation on a Continuous Spectrum

  Alexander Hillsley, et al., bioRxiv - Bioengineering 2022

  Quote: ... Primary antibody (mouse anti – α-SMA, 3 μg/mL, Abcam) was then added and cells were left at 4 °C overnight ...
• GDV1 C-terminal truncation of 39 amino acids disrupts sexual commitment in Plasmodium falciparum

  Marta Tibúrcio, et al., bioRxiv - Microbiology 2020

  Quote: ... and rabbit anti-Histone 3 (1:2000 dilution, abcam ab1791) primary antibodies ...
• Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

  Anoop Singh Chauhan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti SUMO2/3 mAb (1:1000 dilution, Abcam, ab81371), rabbit anti RNF8 mAb (1:1000 dilution ...
• Nucleosomal association and altered interactome underlie the mechanism of cataract caused by the R54C mutation of αA-crystallin

  Saad M. Ahsan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... caspase 3 and actin were obtained from Abcam (Cambridge, UK). Alexa Fluor 488 and Alexa Fluor 633 conjugated secondary antibodies were obtained from Thermo Fisher Scientific (Waltham ...
• Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer’s Disease

  Dominic I. Javonillo, et al., bioRxiv - Neuroscience 2021

  Quote: ... Fox 3 protein (NeuN; 1:1000; AB104225; Abcam, Cambridge, MA), Ctip2 (CTIP2 ...
• Ribosome protein mutant cells rely on the GR64 cluster of gustatory receptors for survival and proteostasis in Drosophila

  Michael E. Baumgartner, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Rabbit anti-cleaved Caspase-3 (1:25,000, Abcam, Cat#13847), Rabbit anti-DCP1 (1:2,500 ...
• Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

  Fei Li, et al., bioRxiv - Microbiology 2020

  Quote: ... 3 μL of anti-AR antibody was added (Abcam, ab108341) for immunoprecipitation overnight ...
• A Tissue-Bioengineering Strategy for Modeling Rare Human Kidney Diseases In Vivo

  J.O.R. Hernandez, et al., bioRxiv - Bioengineering 2021

  Quote: ... anti-human cleaved Caspase 3 was purchased from Abcam (ab2302). Primary antibodies were detected with peroxidase-conjugated anti-rabbit or anti-mouse IgG (1:3000 ...
• PKB/AKT attenuates Lewy Body-like pathology in primary neurons via Cathepsins B and D

  Julia Konovalova, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-α-synuclein (Abcam, #ab1903, 1:2000 in 3% milk) and goat-anti-mouse IG (Dako ...
• HSPA8-mediated stability of the CLPP protein regulates mitochondrial autophagy in cisplatin-resistant ovarian cancer cells

  Xinxin Kou, Xiaoxia Yang, Zheng Zhao, Lei Li, bioRxiv - Cancer Biology 2023

  Quote: ... anti-Microtubule-associated protein light chain 3 (LC3B) (ab48394, Abcam), and anti-β-actin antibody (ab8227 ...
• Inflammation plays a critical role in damage to the bronchiolar epithelium induced by Trueperella pyogenes in vitro and in vivo

  Lei Qin, et al., bioRxiv - Immunology 2023

  Quote: ... Caspase-3 and apoptosis inducing factor (AIF) (1:1,000, abcam) were also used in this process ...
• Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans

  Collyn M. Kellogg, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-NeuN (#ab177487, 1:200, lot: GR3250076-3, Abcam), mouse anti-MHC Class I (H-2Db ...
• SUMO interacting motif (SIM) of S100A1 is critical for S100A1 post-translational protein stability

  Zegeye H. Jebessa, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-SUMO1 and anti-SUMO2/3 were obtained from abcam together with the SUMOylation assay kit (#ab139470 ...
• A Single-Cell RNA-Seq Analysis Unravels the Heterogeniety of Primary Cultured Human Corneal Endothelial Cells

  Pere Català, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-CD44 [Hermes-3] (1:400 dilution, Abcam), rabbit polyclonal anti-VMO1 (1:100 dilution ...
• Birth, cell fate and behavior of progenitors at the origin of the cardiac mitral valve

  Batoul Farhat, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-Integrin beta 3 (rabbit 1/500 Abcam ab-119992). Nuclear staining was performed with DAPI (1/10000).
• Microtubule pivoting driven by spindle elongation rescues polar chromosomes to ensure faithful mitosis

  Isabella Koprivec, et al., bioRxiv - Cell Biology 2024

  Quote: ... Rabbit anti-centrin-3 primary antibody (1:1000, ab228690, Abcam) and secondary donkey anti-rabbit Alexa Fluor 647 (1:1000 ...
• Flamingo participates in multiple models of cell competition

  Pablo Sanchez Bosch, et al., bioRxiv - Developmental Biology 2024

  Quote: ... rabbit polyclonal anti- cleaved Caspase 3 (1:200 dilution, Abcam). We used the following secondary antibodies from Thermo Scientific ...
• Terminal Modification, Sequence, and Length Determine Small RNA Stability in Animals

  Ildar Gainetdinov, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Anti-MIWI (Wako, Cat# 017-23451, RRID:AB_2721829, ~5 μg) or anti-MILI (Abcam Cat# ab36764, RRID:AB_777284, ~5 μg) antibodies were incubated with rotation with 30 μl of Protein G Dynabeads (Thermo Fisher ...
• Antagonistic H3K79me-H3K9ac crosstalk determines elongation at housekeeping genes to promote pluripotency

  Coral K. Wille, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 5 ug (or 5 ul if concentration was unknown) of the following antibodies were used H3K79me1 (Abcam, 2886), H3K79me2 (Active Motif ...
• Repolarisation-relaxation dyscoupling and TRPA1 activation permit systolic mechano-arrhythmogenesis

  Breanne A. Cameron, et al., bioRxiv - Physiology 2024

  Quote: ... dantrolene (to stabilise ryanodine receptors; 1 µM for 5 min, from a 5 mM stock in DMSO, Abcam); streptomycin (to non-specifically block mechano-sensitive channels ...
• Circular RNA hsa_circ_0068033 inhibits proliferation and invasion of breast cancer cells through sponging miR-659

  Pengfei Yuan, Liangliang Lei, Dechun Liu, bioRxiv - Cancer Biology 2019

  Quote: ... Rabbit anti-human monoclonal primary antibody B-cell lymphoma-2 (Bcl-2) (Abcam, 1:1,000) and mouse anti-human GAPDH monoclonal primary antibody (Abcam ...
• Interplay between medial nuclear stalling and lateral cellular flow underlies cochlear duct spiral morphogenesis

  Mamoru Ishii, et al., bioRxiv - Developmental Biology 2020

  Quote: ... the samples were fixed with 4% PFA in PBS overnight at 4°C and then blocked by incubation in 10% normal goat serum (Abcam, #ab156046) diluted in 0.1% Triton X-100/PBS (PBT ...
• Sodium valproate protects against neuronal ferroptosis in epilepsy via suppressing lysyl oxidase

  Qin Li, et al., bioRxiv - Neuroscience 2020

  Quote: ... the membranes were then incubated with primary antibodies (Lox, rabbit, 36 KDa, ab31238, 1:600 dilution, Abcam; 4-hydroxynonenal (4-HNE), rabbit ...
• Functional architecture of the synaptic transducers at a central glutamatergic synapse

  Marisa M. Brockmann, et al., bioRxiv - Neuroscience 2020

  Quote: ... neuronal cultures were fixed by incubating cells with a solution of 4% PFA and 4% sucrose for 10 minutes at room temperature before incubation with primary antibody (Abcam, ab6556). In another set of experiments ...
• Biological characteristics of two mesenchymal stem cell lines isolated from the umbilical cord and adipose tissue of a neonatal common hippo (Hippopotamus amphibius)

  Jinpu Wei, et al., bioRxiv - Cell Biology 2021

  Quote: ... or intracellular markers (C-MYC, KLF-4, NANOG, OCT-4 and SOX2) (Santa Cruz, Sc-40; Abcam, ab214666; ab106465; ab18976; ab97959) was performed in the dark at 4°C overnight ...
• The Nuclear Lamina Binds the EBV Genome During Latency and Regulates Viral Gene Expression

  Lisa Beatrice Caruso, et al., bioRxiv - Microbiology 2022

  Quote: ... 5 μg of Lamin B1 antibody (Abcam), or in LCLs and Mutu I ...
• Independence of 3D chromatin conformation and gene regulation during Drosophila dorsoventral patterning

  Elizabeth Ing-Simmons, et al., bioRxiv - Genomics 2020

  Quote: ... or 5 µg of H3K27me3 (Abcam, ab6002) antibody was carried out on chromatin corresponding to 20-25 µl of embryos at 4 °C overnight ...
• Scalable generation of mesenchymal stem cells and adipocytes from human pluripotent stem cells

  Manale Karam, Ihab Younis, Essam M. Abdelalim, bioRxiv - Developmental Biology 2020

  Quote: ... 5 µL Annexin V-FITC (Abcam, # ab14085) and 5 µL propidium iodide (PI ...
• Evolutionary and biochemical analyses reveal conservation of the Brassicaceae telomerase ribonucleoprotein complex

  Kelly Dew-Budd, et al., bioRxiv - Genetics 2019

  Quote: ... 5-10 μL of GFP (Abcam, ab290), TERT ...
• Interferon-γ Increases Sensitivity to Chemotherapy and Provides Immunotherapy Targets in Models of Metastatic Castration-Resistant Prostate Cancer

  Dimitrios Korentzelos, et al., bioRxiv - Cancer Biology 2021

  Quote: ... HLA Class 1 ABC (EMR8-5, Abcam), and GAPDH (D16H11 ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-H4 (ab10158, Abcam, 5 μg/reaction), and normal rabbit IgG (PP64B ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-H3 (ab1791, Abcam, 5 μg/reaction), anti-H4 (ab10158 ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-H2B (ab1790, Abcam, 5 μg/reaction), anti-H3 (ab1791 ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-H1.5 (ab18208, Abcam, 5 μg/reaction), anti-mH2A1 (ab37264 ...
• DLGAP1-AS2-Mediated Phosphatidic Acid Synthesis Confers Chemoresistance via Activation of YAP Signaling

  Yabing Nan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-mH2A1 (ab37264, Abcam, 5 μg/reaction), anti-H2B (ab1790 ...
• Profiling DNA break sites and transcriptional changes in response to contextual fear learning

  Ryan T. Stott, Oleg Kritsky, Li-Huei Tsai, bioRxiv - Neuroscience 2021

  Quote: ... Then 5 ug anti-γH2AX (ab2893; Abcam) or 10 uL anti-HSF1 (clone 4356S ...
• SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling

  Scott B. Biering, et al., bioRxiv - Microbiology 2021

  Quote: ... rabbit anti-integrin alpha 5 (Abcam, ab150361), rabbit anti-ITGB1 (Thermo Fisher Scientific ...
• Single-cell analysis supports a luminal-neuroendocrine trans-differentiation in human prostate cancer

  Baijun Dong, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-Cytokeratin 5 (Abcam, ab52635; For IHC), anti-P63 (Santa Cruz Biotechnology ...
• The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival

  Shanna Dewaele, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 5 μg of human IgG (Abcam, ab2410) or 5 μg of XRN2 (Bethyl laboratories ...
• The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and 5’ transcript length determination in Arabidopsis

  Borja Diego-Martin, et al., bioRxiv - Molecular Biology 2022

  Quote: ... H3 (5 μl/ChIP used, Ab1791, Abcam), H2A (10 μl/ChIP used ...
• Large-area electrical imaging having single neuron resolution using 236,880 electrodes CMOS-MEA technology

  I. Suzuki, et al., bioRxiv - Neuroscience 2022

  Quote: ... and AP-5 (25 µM; ab120003, Abcam) followed by CNQX (30 µM ...
• Effects of pharmacological calcimimetics on colorectal cancer cells over-expressing the human calcium-sensing receptor

  Luca Iamartino, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and blocked in 5% goat serum (Abcam) containing 0.05% Tween 20 in PBS ...
• Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance

  Ruben Schep, et al., bioRxiv - Molecular Biology 2020

  Quote: ... 5 µl of specific antibody (H3K4me1: Abcam ab8895 ...
• Astrocyte-secreted glypican-4 drives APOE4-dependent tau pathology

  Sivaprakasam R. Saroja, et al., bioRxiv - Neuroscience 2021

  Quote: ... APOE4 protein (5 μg/ml, #ab50243, abcam) or GPC4 (5 μg/ml ...
• LncRNA H19X is required for placenta development and angiogenesis through regulating a noncoding RNA regulatory network

  Tongtong Li, et al., bioRxiv - Developmental Biology 2020

  Quote: ... or isotype IgG (5 μg; ab172730; Abcam), and Protein A/G beads overnight at 4°C ...
• Fine-tuning of Epithelial EGFR signals Supports Coordinated Mammary Gland Development

  Alexandr Samocha, et al., bioRxiv - Cell Biology 2020

  Quote: ... Cytokeratin 5 (1:100; ab52635) from Abcam; CD49f-PE-Cy7 (1:100 ...
• Spatial organisation and homeostasis of epithelial lineages at the gastroesophageal junction is regulated by the divergent Wnt mucosal microenvironment

  Naveen Kumar, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rabbit anti-cytokeratin 5-Alexa488 (Abcam, ab193894), mouse anti-p63 (Abcam ...
• Distinct photooxidation-induced cell death pathways lead to selective killing of human breast cancer cells

  Ancély F. dos Santos, et al., bioRxiv - Cancer Biology 2020

  Quote: ... NSA (abcam, Cambridge, United Kingdom, 5 µM); or CA-074 (Millipore ...
• Boron induces osteogenesis by stimulating NaBC1 in cooperation with BMPR1A

  Patricia Rico, et al., bioRxiv - Cell Biology 2020

  Quote: ... anti-BMPR1A (abcam, 5 µg mL-1), anti-integrin α5 (abcam ...