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4951 - 5000 of 10000+ citations for 7 Chloro 1 3 dihydro 5 phenyl 2H 1 4 benzodiazepin 2 thione since 2019

• Heterozygous mutation of Vegfr3 decreases renal lymphatics but is dispensable for renal function

  Hao Liu, et al., bioRxiv - Physiology 2021

  Quote: ... The following antibodies were used at 1:100 unless stated otherwise: Lyve-1 (Abcam, ab14917), Prox1 (Millipore ...
• Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory factor receptor profiles that can be targeted to reduce immune suppression

  Tyler J. Alban, et al., bioRxiv - Immunology 2019

  Quote: ... Phospho-Histone3 (1:500, catalog # 06-570, MillopreSigma) and Ki67 (1:1,000, catalog # ab15580, Abcam) antibodies were allowed to bind overnight at 4 °C ...
• Stress-relief function of migrasomal autophagosome formed by inhibition of autophagosome/lysosome fusion

  Seon Yong Lee, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cells were incubated with LAMP-1 antibody (1:200; abcam, Cat. # ab25630, Cambridge, MA, USA) and calnexin antibody (1:200 ...
• Long-term, functional culture and in vitro manipulation of adult mouse cardiomyocytes

  Neal I. Callaghan, et al., bioRxiv - Cell Biology 2019

  Quote: ... mouse monoclonal PLN [2D12] antibody (1:500 for IF, 1:1000 for WB; ab2865, Abcam), mouse monoclonal FLAG antibody (1:500 for IF ...
• CRP immunodeposition and proteomic analysis in abdominal aortic aneurysm

  Eun Na Kim, et al., bioRxiv - Pathology 2020

  Quote: ... we performed immunohistochemical staining with antibodies for monocyte chemoattractant protein-1 (MCP-1, ab9669, Abcam), CD68 for macrophages (M0814 ...
• Fat Tissue Regulates the Pathogenesis and Severity of Cardiomyopathy in Murine Chagas Disease

  Kezia Lizardo, et al., bioRxiv - Pathology 2020

  Quote: ... ATP binding cassette transporter (ABCA)-1-specific mouse monoclonal antibody (1:500 dilution, AB.H10, Abcam), Phospho-perilipin1 (Ser522)-specific mouse monoclonal antibody (1:1000 dilution ...
• Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila

  Evelyn L. Eastwood, et al., bioRxiv - Molecular Biology 2021

  Quote: ... anti-Lamin (1:200; Developmental Studies Hybridoma Bank ADL67.10) anti-His3 (1:1,000; abcam ab10799), anti-DYNLL1 (1:1,000 ...
• Colon Innervating TRPA1 Positive Nociceptors Influence Mucosal Health In Mice

  Vibhu Kumar, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Zona occludens-1 (Zo1)- (1:200 prepared in 2.5% goat serum, Cat. No. ab216880 Abcam), Occludin (Occ ...
• Conserved and Divergent Modulation of Calcification in Atherosclerosis and Aortic Valve Disease by Tissue Extracellular Vesicles

  Mark C. Blaser, et al., bioRxiv - Systems Biology 2020

  Quote: ... then stained with rabbit anti-mouse bridging antibody (Abcam ab6709, 1:50 in 1% BSA) for 10 minutes ...
• Laser capture microdissection coupled mass spectrometry (LCM-MS) for spatially resolved analysis of formalin-fixed and stained human lung tissues

  Jeremy A. Herrera, et al., bioRxiv - Biochemistry 2019

  Quote: ... and probed with primary antibody (TNC, 1:500, Abcam, ab108930; LAMB1, 1:1,000, Abcam, ab16048) overnight in 10% blocking solution ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Nanog (14-5761□80 eBioscience, 1/100, anti ATP-b (Ab14730, Abcam – 1:200). Alexa-Fluor conjugated secondary antibodies (Thermo Fisher Scientific ...
• Dock5 is a new regulator of microtubule dynamic instability through GSK3β inhibition in osteoclasts

  Sarah Guimbal, et al., bioRxiv - Cell Biology 2019

  Quote: ... rabbit anti-Dock5 (1/2000, homemade) and rabbit anti-histone H3 (1/5000, Abcam, #1791). Signals were visualized by the ECL Western Lightning Plus detection system (Perkin Elmer ...
• Astrocytes improve neuronal health after cisplatin treatment through mitochondrial transfer

  Krystal English, et al., bioRxiv - Neuroscience 2019

  Quote: ... anti-GFAP (1:200, Acris, Rockville, MD) and anti-Olig2 (1:400, Abcam, Cambridge, UK) antibody ...
• Single cell RNA-seq identifies developing corneal cell fates in the human cornea organoid

  George Maiti, et al., bioRxiv - Developmental Biology 2021

  Quote: ... anti-rabbit KRT5 (1:50; #ab64081) and anti-mouse KRT3 (1:100; #ab77869) from abcam; anti-rabbit TP63 (1:100 ...
• Somatic mutations in CTCF zinc fingers produce cellular phenotypes explained by structure-function relationships

  Charles G Bailey, et al., bioRxiv - Cancer Biology 2021

  Quote: ... HA epitope mouse monoclonal (HA.11, Covance; 1:5,000) and GAPDH (ab8245, Abcam; 1:5,000). Secondary antibodies include ...
• AP-4 mediates vesicular transport of the 2-AG endocannabinoid producing enzyme DAGLB

  Alexandra K. Davies, et al., bioRxiv - Cell Biology 2020

  Quote: ... rabbit anti-DAGLB 1:1000 for WB and 1:800 for IF (Abcam Cat# ab191159), chicken anti-GFP 1:500 for IF (Abcam Cat# ab13970 ...
• Comparison of endogenously expressed fluorescent protein fusions behaviour for protein quality control and cellular aging research

  Kara L. Schneider, et al., bioRxiv - Molecular Biology 2021

  Quote: ... for 1 h followed by probing with primary anti-Hsp104 (ab69549, Abcam, 1:2000 dilution) and anti-Pgk1 (ab90787 ...
• A new strategy for identifying polysialylated proteins reveals they are secreted from cancer cells as soluble proteins and as part of extracellular vesicles

  Carmanah Hunter, et al., bioRxiv - Biochemistry 2022

  Quote: ... then incubated with either 1:1600 α-GM130 or 1:100 α-QSOX2 (Abcam ab121376) in 3 % BSA ...
• Different biological effects of exposure to far-UVC (222 nm) and near-UVC (254 nm) irradiation

  Renata Spagolla Napoleão Tavares, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-TIMP1 (1:250; ab216432) and anti-MMP9 [RM1020] (1:100; ab283575) antibodies (Abcam, EUA). Secondary goat anti-rabbit Alexa Fluor 546 or goat anti-rabbit Alexa Fluor 488 antibodies (1:1000 ...
• Cell surface receptors TREM2, CD14 and integrin α_Mβ₂ drive sinking engulfment in phosphatidylserine-mediated phagocytosis

  Daan Vorselen, et al., bioRxiv - Cell Biology 2022

  Quote: ... Cells were incubated with primary antibody for 1 h for ITGAM (Abcam, ab8878, 1:100), TREM2 (Invitrogen ...
• Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity

  Capria Rinaldi, et al., bioRxiv - Systems Biology 2022

  Quote: ... rabbit anti-Rab10 (phospho-T73) (abcam, #ab241060, 1:100 for IF, 1:500 for WB), rabbit anti-Rab8A (Cell Signaling Technology ...
• Extracellular Matrix Regulates Neuronal Chloride Concentration via K⁺-Cl⁻-Cotransporter 2

  Tushar Devanand Yelhekar, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti‐α‐fodrin (1:5000; Enzo, clone AA6) and anti‐β‐tubulin (1:10000; Abcam) were used to stain KCC2 ...
• Cohesin is involved in transcriptional repression of stage-specific genes in the human malaria parasite

  Catarina Rosa, et al., bioRxiv - Molecular Biology 2022

  Quote: ... Aldolase was detected with anti-aldolase-HRP (Abcam ab38905, 1:5,000 in 1% milk-PBST). HRP signal was developed with SuperSignal West Pico Plus chemiluminescent substrate (Thermo Fisher 34580 ...
• Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

  Michelle M. Frank, et al., bioRxiv - Neuroscience 2022

  Quote: ... The following primary antibody concentrations were used: Mouse anti-CGRP (Abcam, 1:500-1:1,000); Rabbit anti-NPY (Cell Signaling ...
• Encoding of hunger by the neuronal epigenome slows aging in Drosophila

  KJ Weaver, RA Holt, E Henry, SD Pletcher, bioRxiv - Physiology 2022

  Quote: ... mouse anti-nc82 (DSHB 1:20) and rabbit anti-histone H3 (abcam, ab1791 1:20000) were used for primary antibody staining ...
• Diversity within olfactory sensory derivatives revealed by the contribution of Dbx1 lineages

  Frédéric Causeret, et al., bioRxiv - Developmental Biology 2022

  Quote: ... goat anti-OMP (Wako #019-22291, 1:1000) rat anti-CTIP2 (Abcam ab18456, 1:300) mouse anti-Tubulin β3 (Tuj1 ...
• Enhanced cardiac mitochondrial biogenesis by nitro-oleic acid remedies diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction

  Marion Müller, et al., bioRxiv - Pathology 2024

  Quote: ... and glucagon (ab92517, 1:2000, Alexa Fluor 488-conjugated secondary antibody ab150077, 1:1000, Abcam). Nuclei were visualized by DAPI (Fluoroshield ...
• A Novel Pathway Implicated in Regulating Cognitive disfunction in a Drosophila Alzheimer’s Disease Model through Acer Inhibition and CG2233 Modulation

  Judy Ghalayini, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-CG2233 (1:1000) and mouse anti-alpha tubulin (1:1000) (abcam, Cat #ab7291). Primary antibody solution was removed ...
• High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen

  Wan-ping Yang, et al., bioRxiv - Physiology 2023

  Quote: ... The membranes were incubated with the following antibodies: HO-1 (1:2000, Abcam, ab13243, USA); Ft-L (1:1000 ...
• Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression

  Giusy Pizzirusso, et al., bioRxiv - Neuroscience 2024

  Quote: ... Primary antibodies: 1:1000 anti-GABA A Receptor alpha 1 polyclonal rabbit antibody (#ab33299, Abcam), 1:1000 anti-Glutamate Receptor 1 (AMPA subtype ...
• Skin keratinocyte-derived SIRT1 and BDNF modulate mechanical allodynia in mouse models of diabetic neuropathy

  Jennifer O’Brien, et al., bioRxiv - Neuroscience 2024

  Quote: ... chicken anti-neurofilament heavy chain (NFH) (Abcam, ab4680, 1:50 or Aves Labs, 1:50), rabbit anti-DsRed (Takara ...
• High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen

  Wan-ping Yang, et al., bioRxiv - Physiology 2023

  Quote: ... CD11b (1:100, 14-0112-82, Thermo, USA) and CD68 (1:100, ab125212, Abcam, USA), respectively ...
• Pathway choice in the alternative telomere lengthening in neoplasia is dictated by replication fork processing mediated by EXD2’s nuclease activity

  Ronan Broderick, et al., bioRxiv - Molecular Biology 2023

  Quote: ... PML (E-11 sc-377390, Santa Cruz Biotechnology, 1:500 or Ab96051, Abcam, 1:500), POLD3 (Abnova ...
• The circadian clock is a pacemaker of the axonal regenerative ability

  Francesco De Virgiliis, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Tuj1 (1:500, Mouse, Novus NB100-1612) anti-CD68 (1:200, Rabbit, Abcam, ab125212), anti-NH200 (1:1000 ...
• GABAergic LRP1 is a key link between obesity and memory function

  Aaron Aykut Uner, et al., bioRxiv - Neuroscience 2023

  Quote: ... and anti-N-methyl-D-aspartate receptor 1 (NMDAR1) antibody (dilution; 1:100, Abcam (ab193310)) ...
• Transcriptional regulation of Dyskerin via canonical WNT signaling modulates sphingolipid biosynthesis and drives colorectal cancer

  Shivansh Nigam, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1:3000 diluted β-catenin (CST, D10A8) and 1:5000 diluted β-actin (Abcam, ab6276) followed by overnight incubation at 4°C ...
• Apo- and holo- transferrin differentially interact with ferroportin and hephaestin to regulate iron release at the blood-brain barrier

  Stephanie L. Baringer, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary antibodies used were the following: myelin basic protein 1 (MBP1, Abcam, ab22460, 1:500), ferritin (Abcam ...
• Phosphorylation Status Of MUS81 Is A Modifier Of Olaparib Sensitivity In BRCA2-Deficient Cells

  Francesca Blandino, et al., bioRxiv - Cell Biology 2023

  Quote: ... immunofluorescences were performed as above (anti-SMARCAL1, Abcam, 1:100; anti-RAD51, Abcam, 1:1000) and nuclei were stained with DAPI.
• Phosphorylation Status Of MUS81 Is A Modifier Of Olaparib Sensitivity In BRCA2-Deficient Cells

  Francesca Blandino, et al., bioRxiv - Cell Biology 2023

  Quote: ... immunofluorescences were performed as above (anti-SMARCAL1, Abcam, 1:100; anti-RAD51, Abcam, 1:1000) and nuclei were stained with DAPI.
• Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

  Aitor Martinez, et al., bioRxiv - Neuroscience 2023

  Quote: The following secondary antibodies were used: Goat anti-mouse-HRP (Abcam, Ab6789-1, 1:10000), Goat anti-rabbit-HRP (Invitrogen ...
• TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade

  Yan Xiong, et al., bioRxiv - Cell Biology 2023

  Quote: ... IKKα Kinase (Cat# ab32041) (1:5000) and WDR68 (Cat# ab138490) (1:5000) were from Abcam; antibodies to GAPDH (Cat# 60004-1-Ig ...
• Early life pain alters the response to an immune challenge in adult male and female rats

  Morgan G. Gomez, et al., bioRxiv - Neuroscience 2023

  Quote: ... A 1:6 series of brain slices were processed for Fos (1:30k, ab208942, Abcam) as described above ...
• Replication stress underlies genomic instability at CTCF/cohesin-binding sites in cancer

  Elangoli Ebrahimkutty Faseela, et al., bioRxiv - Genomics 2023

  Quote: ... primary antibodies (CTCF: D31H2 CST 1:600, MRE11: ab214 Abcam 1:600, PCNA: ab29 Abcam 1:500 ...
• Reciprocal inflammatory signals establish profibrotic cross-feeding metabolism

  Preeti Yadav, et al., bioRxiv - Immunology 2023

  Quote: ... Conditioned media Arginase 1 levels were measured using Mouse Arginase 1 ELISA Kit (ab269541, Abcam) based on the manufacturer’s protocol ...
• Brazilin is a Natural Product Inhibitor of the NLRP3 Inflammasome

  Emily McMahon, et al., bioRxiv - Molecular Biology 2023

  Quote: ... rabbit anti-mouse caspase-1 + p10 + p12 monoclonal antibody (1.87 µg ml−1; Abcam, ab179515), rabbit anti-mouse gasdermin D antibody (0.6 µg ml−1 ...
• SDC4 deletion perturbs intervertebral disc matrix homeostasis and promotes early osteopenia in the aging spine

  Kimheak Sao, Makarand V. Risbud, bioRxiv - Cell Biology 2023

  Quote: ... antigen retrieval method was performed on samples required for collagen 1 (1:100; Abcam, ab34710), collagen II (1:400 ...
• Cell type-specific translational regulation by human DUS enzymes

  Nathan J. Yu, et al., bioRxiv - Biochemistry 2023

  Quote: ... Genomic PCR and western blot (anti-DUS1L, Proteintech, 1:1000; anti-DUS2L, Abcam, 1:1000) were performed to confirm KO.
• Tepsin binds LC3B to promote ATG9A export and delivery at the cell periphery

  Natalie S. Wallace, et al., bioRxiv - Cell Biology 2023

  Quote: ... rabbit anti-ATG9A 1:200 for immunofluorescence and 1:1000 for Western blots (ab108338; Abcam); rabbit anti- LC3B 1:3000 for Western blots (ab48394 ...
• PLK4 homodimerization is required for CEP152 centrosome localization and spindle organization

  Harshita Kasera, Priyanka Singh, bioRxiv - Cell Biology 2023

  Quote: ... anti-CEP152 rabbit polyclonal (Abcam, #ab-183911, 1:2500 in WB, 1:200 in IF), anti-GFP rabbit polyclonal (Sigma ...
• BRN1/2 Function in Neocortical Size Determination and Microcephaly

  Soraia Barão, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-RFP (1:1000, rat monoclonal, 5F8 ChromoTek or 1:1000, rabbit polyclonal, ab62341 Abcam); anti-Pax6 (1:250 ...