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451 - 500 of 1972 citations for 3 7 Diethyl 2 hydrazinoquinoline hydrochloride since 2020

• The scaffolding protein Flot2 regulates cytoneme-based transport of Wnt3 in gastric cancer

  Daniel Routledge, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-Flotillin-2 (Abcam 96507), anti-Flotillin-2 (Abcam ab113661) ...
• Novel phosphorylation of Rab29 that regulates its localization and lysosomal stress response in concert with LRRK2

  Tadayuki Komori, et al., bioRxiv - Molecular Biology 2022

  Quote: ... MLi-2 (50 nM, Abcam), Go6983 (200 nM ...
• The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery

  Lucía Martín Caballero, et al., bioRxiv - Molecular Biology 2021

  Quote: ... H3K9me2 (2 μl, Abcam 1220) and Myc-trap (10 μl ...
• CRISPR/Cas9-mediated gene editing induces neurological recovery in an A53T-SNCA overexpression rat model of Parkinson’s disease

  Hyung Ho Yoon, et al., bioRxiv - Genetics 2020

  Quote: ... 2% goat serum (ab7481, Abcam) and 2% donkey serum (GTX27475 ...
• Voltage-Gated Potassium Channel Kv1.3 as a Therapeutic Target for Pancreatic Ductal Adenocarcinoma

  Weiwei Li, et al., bioRxiv - Cancer Biology 2021

  Quote: ... β-actin (1: 2 000; Abcam). Membranes were then washed with TBST for 3×10 min ...
• Membrane receptor MerTK is a newly identified transcriptional regulator that associates to chromatin as nanoclusters during human DC differentiation

  Kyra. J.E. Borgman, et al., bioRxiv - Immunology 2020

  Quote: ... α-tubulin (YL1/2, Abcam).
• SARS-CoV-2-Triggered Mast Cell Rapid Degranulation Induces Alveolar Epithelial Inflammation and Lung Injury

  Meng-Li Wu, et al., bioRxiv - Microbiology 2021

  Quote: ... and JAM-2 (Abcam, EPR2489), were used ...
• ABO blood group is involved in the quality of the specific immune response

  Sergio Gil-Manso, et al., bioRxiv - Immunology 2021

  Quote: SARS-CoV-2 S1 (Abcam) and RBD (Sino Biological ...
• A live-cell marker to visualize the dynamics of stable microtubules

  Klara I. Jansen, et al., bioRxiv - Cell Biology 2021

  Quote: ... tyrosinated tubulin (YL1/2, Abcam) and detyrosinated tubulin (AB3210 ...
• Impact of Starmerella bacillaris and Zygosaccharomyces bailii on ethanol reduction and Saccharomyces cerevisiae metabolism during mixed wine fermentations

  Angela Capece, et al., bioRxiv - Microbiology 2021

  Quote: ... anti 2-Cys-Prx (Abcam) or anti-Prx-SO3 (abcam ...
• Single-cell analysis supports a luminal-neuroendocrine trans-differentiation in human prostate cancer

  Baijun Dong, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-AR (Abcam, EPR1535(2)) ...
• Methylation of histone H3 lysine 4 is required for maintenance of beta cell function in adult mice

  Ben Vanderkruk, et al., bioRxiv - Cell Biology 2022

  Quote: ... 2 μg H3K4me1 (Abcam, ab8895), 1 μg H3K27ac (Active Motif ...
• MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

  Yadira M. Soto-Feliciano, et al., bioRxiv - Cancer Biology 2022

  Quote: ... H3K4me1 (Abcam; ab8895, Lot:GR114265-2) or normal rabbit IgG (Abcam ...
• Wnt-7a-positive dendritic cytonemes induce synaptogenesis in cortical neurons

  Thomas M. Piers, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-Flotillin-2 (abcam; ab113661), anti-Myosin-X (Santa Cruz C-1 ...
• GolpHCat (TMEM87A): a unique voltage-gated and pH-sensitive cation channel in the Golgi

  Hyunji Kang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 2% goat serum (abcam, ab7481) and 0.03% Triton-X100 (Sigma ...
• Substrate Stiffness Reshapes Layer Architecture and Biophysical Features of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential

  Jack Llewellyn, et al., bioRxiv - Cell Biology 2024

  Quote: ... 2% donkey serum (ab7475, Abcam), 0.3% Triton-x100 in PBS for 1 hours at room temperature ...
• The autism-associated loss of δ-catenin functions disrupts social behaviors

  Hadassah Mendez-Vazquez, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2 μM tetrodotoxin (TTX) (Abcam) was used to block spontaneous Ca2+ activity in cultured cortical neurons ...
• Foxg1 regulates translation of neocortical neuronal genes, including the main NMDA receptor subunit gene, Grin1

  Osvaldo Artimagnella, et al., bioRxiv - Molecular Biology 2023

  Quote: ... clone EPR2481(2) (Abcam #ab109182), 1:5000 ...
• Small molecule activation of m6A mRNA methylation as a novel approach for neuroprotection

  Li-Ying Yu, et al., bioRxiv - Neuroscience 2023

  Quote: ... tunicamycin (2 µM) (ab120296, Abcam) was added and living fluorescent (Dextran Texas Red-containing ...
• Metabolic impact of trans 10, cis 12-conjugated linoleic acid on pai transgenic mice

  Yu Rao, et al., bioRxiv - Physiology 2023

  Quote: ... AMPK ⍺1 + ⍺2 (Abcam, ab207442), FASN (Abcam ...
• CryoET shows cofilactin filaments inside the microtubule lumen

  Camilla Ventura Santos, et al., bioRxiv - Cell Biology 2023

  Quote: ... 2 μM TG (ab147487, Abcam), 2.5 μM CytD & 2 μM TG and ...
• Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma

  Christel FA Ramirez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p-ERK1/2 (ab214036, Abcam) and c-Myc (ab32072 ...
• Physiological role and mechanisms of action for a long noncoding haplotype region

  Hong Xue, et al., bioRxiv - Genetics 2024

  Quote: ... and 2 µM forskolin (Abcam) for 2 days and purified with CD144 (VE-Cadherin ...
• A single-cell map of hypertension

  Qiongzi Qiu, et al., bioRxiv - Physiology 2024

  Quote: ... and 2 µM forskolin (Abcam) for 2 days ...
• Activity-Dependent Localization and Heterogeneous Dynamics of STIM1 and STIM2 at ER-PM contacts in Hippocampal Neurons

  Arun Chhikara, et al., bioRxiv - Neuroscience 2024

  Quote: ... Fura-2 AM (abcam, ab120873), HRP anti-Guinea Pig (Jackson IR ...
• Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice

  Mitra Esfandiarei, et al., bioRxiv - Neuroscience 2024

  Quote: ... MMP-2 (1:100, AbCam, Cambridge ...
• Global and genetic regulation of gene expression in human endothelial and vascular smooth muscle cells

  Pengyuan Liu, et al., bioRxiv - Genomics 2024

  Quote: ... and 2 µM forskolin (Abcam) for 2 days ...
• Dysregulated calcium signaling in the aged macaque entorhinal cortex associated with tau hyperphosphorylation

  S Bathla, et al., bioRxiv - Neuroscience 2024

  Quote: ... calpain 2 (Abcam ab39165,1:1000), PDE4A (Abcam ab14607,1:1000) ...
• Human Stem Cell-derived Kidney Collecting Duct Model via Epithelial Microphysiological Analysis Platform: Epi-MAP

  SoonGweon Hong, et al., bioRxiv - Bioengineering 2024

  Quote: ... anti-Aquaporin 2 (Abcam, ab199975), anti-Acetyl-α-Tubulin (Cell Signaling ...
• Sonicated fibrils of huntingtin exon-1 preferentially seed neurons and produce toxic assemblies

  Anjalika Chongtham, et al., bioRxiv - Neuroscience 2021

  Quote: ... was used to detect intracellular HTT fibrils and caspase-3 activity in untreated and treated neurons was monitored by immunocytochemistry using anti-caspase-3 antibody (Abcam, Cat# 32351, 1:1000). Images were captured using a Leica SP8 confocal microscope and analyzed by LAS X software ...
• Astrocytic striatal GABA transporter activity governs dopamine release and shows maladaptive downregulation in early parkinsonism

  Bradley M. Roberts, et al., bioRxiv - Neuroscience 2020

  Quote: ... or 1:1,000 rabbit anti-GABA transporter 3 (Abcam, AB181783). Blots were incubated with HRP-conjugated secondary anitbodies at 1:3,000 for 1 h at room temperature and bands developed using ECL Prime Western Blotting Detection Reagent (GE Healthcare) ...
• Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA lnc-Rewind in muscle stem cells

  Andrea Cipriano, et al., bioRxiv - Cell Biology 2020

  Quote: ... incubation with 3 μg of immobilized anti-H3K9me2 (Abcam ab1220) or rabbit IgG antibodies ...
• Adhesion-mediated heterogeneous actin organization governs apoptotic cell extrusion

  Anh Phuong Le, et al., bioRxiv - Cell Biology 2020

  Quote: ... Caspase-3 indicator DEVD-FMK conjugated to Sulfo-rhodamine (Abcam) was used at 1:1000 dilution and incubated with the cells 30 min before experiment ...
• The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity

  Adrienne E. D. Stormo, et al., bioRxiv - Molecular Biology 2021

  Quote: ... rabbit anti-phospho-Ser910 LRRK2 (Abcam, UDD 1 15(3)) ...
• Recruitment of transcriptional effectors by Cas9 creates cis regulatory elements and demonstrates distance-dependent transcriptional regulation

  Jubran Boulos, et al., bioRxiv - Genomics 2022

  Quote: ... with anti-Histone 3 acetyl K27 (H3K27ac) antibody (Abcam ab4729) and anti-Histone 3 k4 monomethyl (H3k4mm ...
• Non-canonical H3K79me2-dependent pathways promote the survival of MLL-rearranged leukemia

  William F. Richter, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 3 μg of anti-H3K79me2 (Abcam cat # ab3594, lot # GR173874); 3 μg of anti-H3K4me3 (Abcam cat # 12209 ...
• LncRNA-UCA1 Alleviates Septic Acute Kidney Injury through Regulating Endoplasmic Reticulum Stress in LPS-treated HK-2 Cells

  TT Yu, FL Cai, J Niu, bioRxiv - Cell Biology 2021

  Quote: ... they were incubated with primary antibodies (pro-Caspase-3, Abcam, rabbit ...
• Prior hypoxia exposure enhances murine microglial inflammatory gene expression in vitro without concomitant H3K4me3 enrichment

  Elizabeth A. Kiernan, et al., bioRxiv - Neuroscience 2020

  Quote: ... vehicle (DMSO) or 3 µM BOT-64 (Abcam; Cambridge, MA) was added prior to the start of Hx ...
• A Strategy to Quantify Myofibroblast Activation on a Continuous Spectrum

  Alexander Hillsley, et al., bioRxiv - Bioengineering 2022

  Quote: ... Primary antibody (mouse anti – α-SMA, 3 μg/mL, Abcam) was then added and cells were left at 4 °C overnight ...
• GDV1 C-terminal truncation of 39 amino acids disrupts sexual commitment in Plasmodium falciparum

  Marta Tibúrcio, et al., bioRxiv - Microbiology 2020

  Quote: ... and rabbit anti-Histone 3 (1:2000 dilution, abcam ab1791) primary antibodies ...
• Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

  Anoop Singh Chauhan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti SUMO2/3 mAb (1:1000 dilution, Abcam, ab81371), rabbit anti RNF8 mAb (1:1000 dilution ...
• Nucleosomal association and altered interactome underlie the mechanism of cataract caused by the R54C mutation of αA-crystallin

  Saad M. Ahsan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... caspase 3 and actin were obtained from Abcam (Cambridge, UK). Alexa Fluor 488 and Alexa Fluor 633 conjugated secondary antibodies were obtained from Thermo Fisher Scientific (Waltham ...
• Systematic phenotyping and characterization of the 3xTg-AD mouse model of Alzheimer’s Disease

  Dominic I. Javonillo, et al., bioRxiv - Neuroscience 2021

  Quote: ... Fox 3 protein (NeuN; 1:1000; AB104225; Abcam, Cambridge, MA), Ctip2 (CTIP2 ...
• Ribosome protein mutant cells rely on the GR64 cluster of gustatory receptors for survival and proteostasis in Drosophila

  Michael E. Baumgartner, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Rabbit anti-cleaved Caspase-3 (1:25,000, Abcam, Cat#13847), Rabbit anti-DCP1 (1:2,500 ...
• Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide

  Fei Li, et al., bioRxiv - Microbiology 2020

  Quote: ... 3 μL of anti-AR antibody was added (Abcam, ab108341) for immunoprecipitation overnight ...
• A Tissue-Bioengineering Strategy for Modeling Rare Human Kidney Diseases In Vivo

  J.O.R. Hernandez, et al., bioRxiv - Bioengineering 2021

  Quote: ... anti-human cleaved Caspase 3 was purchased from Abcam (ab2302). Primary antibodies were detected with peroxidase-conjugated anti-rabbit or anti-mouse IgG (1:3000 ...
• PKB/AKT attenuates Lewy Body-like pathology in primary neurons via Cathepsins B and D

  Julia Konovalova, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-α-synuclein (Abcam, #ab1903, 1:2000 in 3% milk) and goat-anti-mouse IG (Dako ...
• Inflammation plays a critical role in damage to the bronchiolar epithelium induced by Trueperella pyogenes in vitro and in vivo

  Lei Qin, et al., bioRxiv - Immunology 2023

  Quote: ... Caspase-3 and apoptosis inducing factor (AIF) (1:1,000, abcam) were also used in this process ...
• Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans

  Collyn M. Kellogg, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-NeuN (#ab177487, 1:200, lot: GR3250076-3, Abcam), mouse anti-MHC Class I (H-2Db ...
• SUMO interacting motif (SIM) of S100A1 is critical for S100A1 post-translational protein stability

  Zegeye H. Jebessa, et al., bioRxiv - Biochemistry 2023

  Quote: ... anti-SUMO1 and anti-SUMO2/3 were obtained from abcam together with the SUMOylation assay kit (#ab139470 ...