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1 - 50 of 8494 citations for CD366 Tim 3 Antibody APC since 2020

• HIV-1 controllers possess a unique CD8+ T-cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

  Amber D Jones, et al., bioRxiv - Immunology 2024

  Quote: ... and/or anti-Tim-3 (CD366) antibody (BioLegend, UltraLEAF purified anti-human ...
• Emergence and suppressive function of Tr1 cells in glomerulonephritis

  Shiwa Soukou-Wargalla, et al., bioRxiv - Immunology 2023

  Quote: ... CD366 (TIM-3) (BV 421, BioLegend, clone RMT3-23 ...
• Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer

  Yijuan Zhang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PE anti-mouse CD366 (Tim-3) (Biolegend), PE/Cy7 anti-mouse CD279 (PD-1 ...
• Non-productive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immunity responses

  Julia Kazmierski, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-TIM-3/CD366-FITC (#345022; Biolegend). To determine ACE2 cell surface expression ...
• Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

  Julia Prigann, et al., bioRxiv - Microbiology 2023

  Quote: ... and anti-TIM-3/CD366-FITC (#345022; Biolegend). For intracellular immunostaining ...
• Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia

  Diego Gilioli, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD366 (TIM-3) BV421 (cat#345008 from BioLegend), CD223 (LAG-3 ...
• Identification of small molecule enhancers of NK cell tumoricidal activity via a tumor microenvironment-mimicking co-culture assay

  Aylin Binici, et al., bioRxiv - Immunology 2024

  Quote: ... and TIM-3(F38-2E2)-APC-Fire 750 (BioLegend (San Diego)) ...
• Secreted filarial nematode galectins modulate host immune cells

  Hannah J. Loghry, et al., bioRxiv - Immunology 2022

  Quote: ... Tim-3 was either neutralized by anti-human Tim-3 antibodies (10 µg/mL) (Biolegend) for 1 h prior to treatment or through knockdown via duplexed siRNA (Integrated DNA Technologies ...
• Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2023

  Quote: ... TIM-3-BV711 (Biolegend), LAG-3-APC-eFluor 780 (Invitrogen) ...
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... TIM-3-BV711 (Biolegend), LAG-3-APC-eFluor 780 (Invitrogen) ...
• HSV-1 Oncolytic Virus Targeting CEACAM6-Expressing Tumors Using a Bispecific T-Cell Engager

  Yanal M. Murad, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Tim-3 (BV510, BioLegend), LAG-3 (BV605) ...
• Enhancing Mucosal-Associated Invariant T (MAIT) cell function and expansion with human selective serum

  Daniel Labuz, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3-BV421 (Biolegend), and anti-human MR1-5-OP-RU Tetramer (NIH Tetramer Core Facility) ...
• Expression of Tim-3 drives naïve Treg to an effector-like state with enhanced suppressive activity

  Hridesh Banerjee, et al., bioRxiv - Immunology 2020

  Quote: ... Tim-3 clone RMT 3-23 (BioLegend) and clone FAB1529 (R&D) ...
• BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity

  Taylor L. Hickman, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and TIM-3 (F38-2E2) (Biolegend) were used to evaluate T cell phenotype ...
• Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

  Tomokazu S. Sumida, et al., bioRxiv - Immunology 2020

  Quote: ... anti-Tim-3 (F38-2E2, Biolegend), anti-IFN-γ (4S.B3 ...
• Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses

  Yang Li, et al., bioRxiv - Immunology 2022

  Quote: ... Tim-3 (BioLegend, 119721, RMT3-23), LAG-3 (BioLegend ...
• Tregs constrain CD8⁺ T cell priming required for curative intratumorally anchored anti-4-1BB immunotherapy

  Joseph R. Palmeri, et al., bioRxiv - Immunology 2023

  Quote: ... αTIM-3-BV785 (RMT3-23, Biolegend), αTCF1/TCF7-AF488 (C63D9 ...
• Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands

  Katrin Raute, et al., bioRxiv - Immunology 2022

  Quote: ... α-CCR10-APC (clone 6588-5) and α-TIM-3-PE-Cy7 (clone F38-2E2) from BioLegend. α-ULPB2/5/6 (mouse ...
• Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

  Sharon Yunger, et al., bioRxiv - Immunology 2022

  Quote: ... FITC-TIM-3 (clone F38-2E2, BioLegend), FITC-LAG-3 (clone 11C3C65 ...
• The transcription factor IRF-5 is essential for the metabolic rewiring of CD8 T cells during chronic infection

  Linh Thuy Mai, et al., bioRxiv - Immunology 2024

  Quote: ... anti TIM-3-BV605 (RMT3-23, Biolegend), anti CD44-PE-Cy7 (IM7 ...
• SOX2-induced IL1α-mediated immune suppression drives epithelial dysplasia malignant transformation

  Hülya F. Taner, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Tim-3 (clone RMT3-23, BioLegend), anti-TCRγ/δ (clone GL3 ...
• NRF2-dependent regulation of the prostacyclin receptor PTGIR drives CD8 T cell exhaustion

  Michael S. Dahabieh, et al., bioRxiv - Immunology 2024

  Quote: ... TIM-3 BV711 (#119727, Clone RMT3-23, Biolegend), PD-1 BUV737 (#749306 ...
• PD-1 blockade enhances HIV-1 vaccine-induced CD8⁺ T-cell responses in PWH early ART-treated

  Miguel Marin, et al., bioRxiv - Immunology 2024

  Quote: ... and TIM-3 (PE, clone F38-2E2, Biolegend) antibodies for 25 minutes ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

  Aidan M. Tousley, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... TIM-3 (BV510 or BV650, Clone F38-2E2, BioLegend), LAG-3 (PE ...
• Cancer-associated adipocytes mediate CD8⁺T cell dysfunction via FGF21-driven lipolysis

  Sumiya Dalangood, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-TIM-3-PE/Cy7 (cat#134009, CloneB8.2C12, Biolegend), anti-LAG3-Percp/Cyanine5.5 (cat#125211 ...
• Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas

  Amy Y. Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TIM-3 BV711 (clone RMT3-23, Biolegend 119727, 1:200), Foxp3 FITC (clone FJK-16s ...
• A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

  Shuwei Liang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PE-Cy7-conjugated CD366 (BioLegend Cat# 134010); BD Biosciences Cat# 552094) ...
• STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

  Taylor L. Sheehy, et al., bioRxiv - Bioengineering 2024

  Quote: ... CD366/Tim3 (RMT3-23, PE-Dazzle594, Biolegend), CD223/LAG3 (C9B7W ...
• Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART

  Oscar Blanch-Lombarte, et al., bioRxiv - Immunology 2023

  Quote: ... we used Ultra-LEAF™ purified anti-human TIM-3 antibody (10μg/ml, clone F38-2E2, Biolegend) or its respective isotype Ultra-LEAF™ purified mouse IgG1 antibody (10μg/ml ...
• MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection

  Sharon Khuzwayo, et al., bioRxiv - Immunology 2020

  Quote: ... and 1:50 of anti-TIM-3 BV785 (F38-2E2, BioLegend). Tetramer staining was performed in the dark at room temperature for 40 minutes ...
• Mitochondrial respiration contributes to the interferon gamma response in antigen presenting cells

  Michael C. Kiritsy, et al., bioRxiv - Immunology 2020

  Quote: ... CD40 (APC anti-mouse CD40 Antibody, Clone 3/23 Biolegend 124611), or PD-L1 (APC anti-mouse CD274 (B7-H1 ...
• Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis

  Gabriela Pessenda, et al., bioRxiv - Immunology 2024

  Quote: ... TIM-4 (RMT4-54, Biolegend) 1:200 ...
• Cross-Linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model

  Floriana Cremasco, et al., bioRxiv - Immunology 2020

  Quote: ... 3) CD62L APC-Cy7 (BioLegend), huCD45 PE (BioLegend) ...
• T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function

  Johannes Brandi, et al., bioRxiv - Immunology 2021

  Quote: ... αCD366 (Tim-3) BV711(RMT3-23) and αTIGIT PE-Dazzle594 (2G9) were purchased from BioLegend, San Diego ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-TIM-1 (BioLegend, catalog #353903), anti-TIM-4 (BioLegend ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-TIM-4 (BioLegend, catalog #354003), anti-PD-L1 (also labeled with Dazzle 594 ...
• Functional impairment of “helpless” CD8⁺ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

  Verena van der Heide, et al., bioRxiv - Immunology 2024

  Quote: ... with 3 µg of APC-labeled anti-CD8b.2 antibody (clone 53-5.8, Biolegend) 5 min prior to euthanasia to mark vasculature-associated cells in vivo.
• Stage-specific CAR-mediated signaling generates naïve-like, TCR-null CAR T cells from induced pluripotent stem cells

  Sang Pil Yoo, et al., bioRxiv - Bioengineering 2024

  Quote: ... CD107a-APC antibody (Biolegend) was added to each well at a 1:10 dilution ...
• CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

  Ian E. Prise, et al., bioRxiv - Immunology 2023

  Quote: ... rat anti-Tim-4 (RMT4-54, BioLegend) or rabbit anti-CD163 (ab182422 ...
• CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

  Ian E. Prise, et al., bioRxiv - Immunology 2023

  Quote: ... and Tim-4 (RMT4-54) from BioLegend as well as CD163 (TNKUPJ ...
• Single cell multi-omics reveals early elevated function and multiple fates within human progenitor exhausted CD8⁺ T cells

  Curtis Cai, et al., bioRxiv - Immunology 2021

  Quote: ... The first surface marker panel included: BV421 and PerCP/Cy5.5 anti-TIM-3 (clones B8.2C12 and RMT3-23, BioLegend), BV510 anti-PD-1 (EH12.1) ...
• Immunological correlates of protection mediated by a whole organism Cryptococcus neoformans vaccine deficient in chitosan

  Charles A. Specht, et al., bioRxiv - Immunology 2024

  Quote: ... and CD8-APC antibodies (BioLegend). Cells were then fixed and permeabilized using the Intracellular Fixation & Permeabilization Buffer Set ...
• Autophagy inhibition induces AML cell death and enhances the efficacy of chemotherapy under hypoxia

  Hannah R.S. Fay, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and CD38-APC antibodies (BioLegend). Treatment was vehicle or Lys05 (40mg/kg i.p ...
• SARS-CoV-2 variant B.1.1.7 caused HLA-A2⁺ CD8⁺ T cell epitope mutations for impaired cellular immune response

  Chanchan Xiao, et al., bioRxiv - Immunology 2021

  Quote: ... APC labeled human CCR7 antibody (BioLegend), FITC labeled human CD45RA antibody (BioLegend ...
• Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

  Yi Wu, et al., bioRxiv - Microbiology 2022

  Quote: ... APC anti-mouse CD4 antibody (Biolegend), APC/Cyanine7 anti-mouse CD19 antibody (Biolegend) ...
• Maximizing the Anti-tumor Potential of Immune Checkpoint Blockade through Modulation of Myeloid-specific CXCL16 and STAT1 Signaling

  Bhavana Palakurthi, et al., bioRxiv - Cancer Biology 2022

  Quote: ... APC/Cy7 CD11b antibody (BioLegend, 101225), APC anti-mouse CD103 (BioLegend ...
• Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment

  Thillai V. Sekar, et al., bioRxiv - Bioengineering 2023

  Quote: ... APC-conjugated His-tag antibody (Biolegend) was added to the cells treated with no nanobody proteins ...
• Higher-order combinatorial chromatin perturbations by engineered CRISPR-Cas12a for functional genomics

  CC Hsiung, et al., bioRxiv - Genetics 2024

  Quote: Antibodies used: CD55-APC (Biolegend 311312), CD81-PE (Biolegend 349506) ...