Labshake search

1 - 50 of 371 citations for Alpinone 3 Acetate since 2020

• Functional impairment of “helpless” CD8⁺ memory T cells is transient and driven by prolonged but finite cognate antigen presentation

  Verena van der Heide, et al., bioRxiv - Immunology 2024

  Quote: ... Phorbol 12-myristate13-acetate (PMA)/ionomycin-stimulated (Cell Activation cocktail, Biolegend) and unstimulated samples in the absence of peptide were included as positive and negative controls ...
• Expression of Tim-3 drives naïve Treg to an effector-like state with enhanced suppressive activity

  Hridesh Banerjee, et al., bioRxiv - Immunology 2020

  Quote: ... Tim-3 clone RMT 3-23 (BioLegend) and clone FAB1529 (R&D) ...
• Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants

  Miguel Á. Muñoz-Alía, et al., bioRxiv - Microbiology 2022

  Quote: ... a phorbol myristate acetate (PMA)/ionomycin cell stimulation cocktail (Biolegend, San Diego, CA, USA) was used at 2.5 µL/mL ...
• Heparan sulfate regulates amphiregulin signaling towards reparative lung mesenchymal cells during influenza A infection

  Lucas F. Loffredo, et al., bioRxiv - Immunology 2024

  Quote: ... rmIL-3 (Biolegend) was added to media (1 ng/ml) ...
• DCs targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors

  Lucía López-Rodríguez, et al., bioRxiv - Immunology 2024

  Quote: ... single-cell suspensions were stimulated with cell activation cocktail (including phorbol 12-myristate 13-acetate and Ionomycin) (BioLegend) in the presence of Golgi Stop (monensin ...
• Cytotoxic CD4⁺ T cells eliminate senescent cells by targeting cytomegalovirus antigen

  Tatsuya Hasegawa, et al., bioRxiv - Immunology 2023

  Quote: ... cells were treated with 81 nM phorbol 12-myristate 13-acetate (PMA) plus 1.34 µM Ionomycin (BioLegend, 423301) for 30 min ...
• SCCA1/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses

  Liyun Chen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... were stimulated with 500x Cell Activation Cocktail containing 40.5 μM phorbol-12-myristate 13-acetate (PMA) and 669.3 μM ionomycin (Biolegend) in the presence of 5 μg/mL BFA (Biolegend ...
• Molecular and functional diversity of distinct subpopulations of extracellular vesicles from stressed pancreatic beta cells: implications for autoimmunity

  Khem Raj Giri, et al., bioRxiv - Immunology 2020

  Quote: ... CD40 (3/23, BioLegend), CD115 (CSF-1R ...
• Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

  Ann-Kathrin Mattes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... LAG-3 (BioLegend, 369212) or LFA-1 (BD ...
• Inulin prebiotic reinforces host cancer immunosurveillance via γδ T cell activation

  Emilie Boucher, et al., bioRxiv - Immunology 2022

  Quote: ... CD40 (3/23) (Biolegend), CD11b (M1/70) ...
• Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2023

  Quote: ... TIM-3-BV711 (Biolegend), LAG-3-APC-eFluor 780 (Invitrogen) ...
• Bleomycin induced EBV-specific gastric epithelial cell death is enhanced by LMP2A

  Aung Phyo Wai, et al., bioRxiv - Microbiology 2024

  Quote: ... caspase-3 (W20054B; Biolegend), cleaved caspase-3 (Asp175 ...
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... TIM-3-BV711 (Biolegend), LAG-3-APC-eFluor 780 (Invitrogen) ...
• HSV-1 Oncolytic Virus Targeting CEACAM6-Expressing Tumors Using a Bispecific T-Cell Engager

  Yanal M. Murad, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Tim-3 (BV510, BioLegend), LAG-3 (BV605) ...
• Lesion-specific suppression of YAP/TAZ by biomimetic nanodrug ameliorates atherosclerosis development

  Hui-Chun Huang, et al., bioRxiv - Bioengineering 2023

  Quote: ... Histone 3 (BioLegend #819411), YAP/TAZ (Santa Cruz #sc-101199) ...
• Multi-Omic Atlas reveals cytotoxic phenotype and ROS-linked metabolic quiescence as key features of CTL-resistant HIV-infected CD4⁺ T-cells

  Alberto Herrera, et al., bioRxiv - Immunology 2024

  Quote: ... #3 and #4 (Biolegend) were spiked into individual samples ...
• The role of YAP/TAZ signaling in dendritic cell-mediated pathogenesis of insulin resistance and non-alcoholic fatty liver disease

  Alejandro Schcolnik-Cabrera, et al., bioRxiv - Immunology 2024

  Quote: ... cell suspensions were stimulated with phorbol myristate acetate (PMA) and ionomycin in the presence of Brefeldin A (PMA+, BioLegend) for 5h ...
• Mapping glycan-mediated galectin-3 interactions by live cell proximity labeling

  Eugene Joeh, et al., bioRxiv - Biochemistry 2020

  Quote: ... Recombinant galectin-3 (Biolegend # 599706) was then incubated either for 1-2 hrs at RT or overnight at 4°C ...
• Cross-Linking of T cell to B cell lymphoma by the T cell bispecific antibody CD20-TCB induces IFNγ/CXCL10-dependent peripheral T cell recruitment in humanized murine model

  Floriana Cremasco, et al., bioRxiv - Immunology 2020

  Quote: ... 3) CD62L APC-Cy7 (BioLegend), huCD45 PE (BioLegend) ...
• A method for polyclonal antigen-specific T cell-targeted genome editing (TarGET) for adoptive cell therapy applications

  Darya Palianina, et al., bioRxiv - Immunology 2022

  Quote: ... LAG-3-BV711 (11C3C65, Biolegend) and TIGIT-BV605 (A15153G ...
• Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike

  Lihong Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... and human Hashtag 3 (Biolegend) at 4°C for 1 hr ...
• Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses

  Yang Li, et al., bioRxiv - Immunology 2022

  Quote: ... LAG-3 (BioLegend, 125212, C9B7W), ST2 (eBioscience ...
• Distinct effects of disease-associated TREM2 R47H/+ and T66M mutations on iPSC-derived microglia

  Jay Penney, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit-β-Tubulin 3 (BioLegend) and mouse-STEM101 (Takara Bio) ...
• Enhancing Mucosal-Associated Invariant T (MAIT) cell function and expansion with human selective serum

  Daniel Labuz, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3-BV421 (Biolegend), and anti-human MR1-5-OP-RU Tetramer (NIH Tetramer Core Facility) ...
• Enhancing Mucosal-Associated Invariant T (MAIT) cell function and expansion with human selective serum

  Daniel Labuz, et al., bioRxiv - Immunology 2022

  Quote: ... anti-LAG-3-BV786 (Biolegend), anti-CD69-BUV563 (BD Biosciences) ...
• Enhancing Mucosal-Associated Invariant T (MAIT) cell function and expansion with human selective serum

  Daniel Labuz, et al., bioRxiv - Immunology 2022

  Quote: ... anti-LAG-3-BV786 (Biolegend), anti-CD69-APC (Biolegend) ...
• Enhancing Mucosal-Associated Invariant T (MAIT) cell function and expansion with human selective serum

  Daniel Labuz, et al., bioRxiv - Immunology 2022

  Quote: ... anti-LAG-3-BV786 (Biolegend), anti-CD25-BV650 (Biolegend) ...
• Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL

  Caroline Mitiká Watanabe, et al., bioRxiv - Cancer Biology 2024

  Quote: ... KIR2DL2/3 (clone DX27, Biolegend), and KIR2DL1 (clone HP-MA4 ...
• Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease-like ileitis

  Weili Xu, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD5 (53.7-3, Biolegend), anti-CD103 (2E7 ...
• Comprehensive genome editing confers ‘off-the-shelf’ CAR-T cells superior efficacy against solid tumors

  Ryan Murray, et al., bioRxiv - Cell Biology 2023

  Quote: ... PDL1 (29E.2A.3, Biolegend), TCR (IP26 ...
• AxSpA joint tissue is characterised by HLA-DR⁺ tissue resident memory (TRM) and killer cell immunoglobulin-like receptor (KIR)⁺ CD8⁺ T cell subsets

  Feng Liu, et al., bioRxiv - Immunology 2024

  Quote: ... KIRDL2-3 (clone DX27; BioLegend), KIR3DL1 (clone DX9 ...
• Multi-modal pooled Perturb-CITE-Seq screens in patient models define novel mechanisms of cancer immune evasion

  Chris J. Frangieh, et al., bioRxiv - Genomics 2020

  Quote: ... 1×105 TILs were seeded per well of a round bottom 96 well plate and stimulated with phorbol-12-myristate-13-acetate/Ionomycin in the presence of Brefeldin A (Biolegend) for 4 hours as per manufacturer’s instruction ...
• A spike-ferritin nanoparticle vaccine induces robust innate immune activity and drives polyfunctional SARS-CoV-2-specific T cells

  Joshua M. Carmen, et al., bioRxiv - Immunology 2021

  Quote: ... cells were cultured in stimulation media without peptide stimulation or with phorbol 12-myristate 13-acetate (PMA) and ionomycin (BioLegend), respectively ...
• Species-specific CD4⁺ T cells Enable Prediction of Mucosal Immune Phenotypes from Microbiota Composition

  Matthew P. Spindler, et al., bioRxiv - Immunology 2022

  Quote: ... isolated lymphocytes were first restimulated with 5 ng/mL phorbal 12-myristate 13-acetate and 500 ng/mL ionomycin in the presence of monensin (Biolegend) for 3.5 h ...
• Secreted filarial nematode galectins modulate host immune cells

  Hannah J. Loghry, et al., bioRxiv - Immunology 2022

  Quote: ... Tim-3 was either neutralized by anti-human Tim-3 antibodies (10 µg/mL) (Biolegend) for 1 h prior to treatment or through knockdown via duplexed siRNA (Integrated DNA Technologies ...
• Temporal Metabolic Characteristics and Transcriptomic Landscape of Islets and Liver Reveal Dynamic Pathophysiology and Interorgan Crosstalk in High-fat Diet-induced Diabetes

  Rui Gao, et al., bioRxiv - Cell Biology 2020

  Quote: ... cells were stimulated with phorbol myristate acetate (PMA) and ionomycin in the presence of brefeldin A (BioLegend, San Diego, CA, USA) for 5 h before surface staining ...
• BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved antitumor activity

  Taylor L. Hickman, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and TIM-3 (F38-2E2) (Biolegend) were used to evaluate T cell phenotype ...
• Expression of extracellular Hsp90 is a molecular signature of T cell activation, providing a means to image and target T Cell activation in autoimmune disease

  Scott A. Scarneo, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... 3:20,000 anti-CD28 (BioLegend 302913), and 1:10,000 (30 IU/mL ...
• Probiotic-guided CAR-T cells for universal solid tumor targeting

  Rosa L. Vincent, et al., bioRxiv - Bioengineering 2021

  Quote: ... LAG-3 BV421 (Biolegend clone 11C3C65), PD-1 PE-Cy7 (Biolegend clone EH12.2H7).
• A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses

  Huan Du, et al., bioRxiv - Neuroscience 2021

  Quote: ... mouse anti-Galectin-3 (BioLegend, 126702), goat anti-Galectin-3 (R&D Systems ...
• Role of T cells in intrauterine administration of activated peripheral blood mononuclear cells in recurrent implantation failure

  Guillaume Ricaud, et al., bioRxiv - Immunology 2021

  Quote: ... anti-GATA-3/BV421 (Biolegend, USA), anti-IL-4/BV510 (Biolegend ...
• Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

  Tomokazu S. Sumida, et al., bioRxiv - Immunology 2020

  Quote: ... anti-Tim-3 (F38-2E2, Biolegend), anti-IFN-γ (4S.B3 ...
• Antigenic Sensitivity of Membrane-Proximal Targeting Chimeric Antigen Receptors can be Fine-Tuned through Hinge Truncation

  Scott McComb, et al., bioRxiv - Immunology 2021

  Quote: ... OKT-3 stock (BioLegend Inc, USA) was diluted to 50mg/ul ...
• Mapping the SARS-CoV-2 spike glycoprotein-derived peptidome presented by HLA class II on dendritic cells

  Robert Parker, et al., bioRxiv - Immunology 2020

  Quote: ... and CD11c (S-HCL-3, Biolegend) for 20 minutes at room temperature ...
• Connecting secretome to hematopoietic stem cell phenotype shifts in an engineered bone marrow niche

  Aidan E. Gilchrist, Brendan A.C. Harley, bioRxiv - Bioengineering 2020

  Quote: ... recombinant murine MMP-3 (#552704, BioLegend), recombinant murine c-RP (#50409-M08H ...
• Cell-Intrinsic and Extrinsic Effects of Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia

  Fei Fei, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Galectin-3 (Biolegend, San Diego, USA), phospho-ERK1/2 ...
• Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses

  Yang Li, et al., bioRxiv - Immunology 2022

  Quote: ... Tim-3 (BioLegend, 119721, RMT3-23), LAG-3 (BioLegend ...
• Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

  Yaeko Nakajima-Takagi, et al., bioRxiv - Immunology 2022

  Quote: ... recombinant mouse IL-3 (575506; Biolegend), and recombinant murine GM-CSF (315-03 ...
• Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa

  Maria E. Mercau, et al., bioRxiv - Immunology 2022

  Quote: ... Galectin-3 (BioLegend clone M3/38), CD11c (BioLegend clone N418) ...
• Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

  Sharon Yunger, et al., bioRxiv - Immunology 2022

  Quote: ... FITC-LAG-3 (clone 11C3C65, BioLegend) APC-CD25 (clone BC96 ...