Labshake search

401 - 450 of 2115 citations for 7 Bromo 4 chlorothieno 3 2 d pyrimidine since 2019

• Stearoyl-CoA desaturase mediated monounsaturated fatty acid availability supports humoral immunity

  Xian Zhou, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (10 ng/mL; Biolegend), IL-2 (10 unit/mL ...
• Role of T cells in intrauterine administration of activated peripheral blood mononuclear cells in recurrent implantation failure

  Guillaume Ricaud, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL-4/BV510 (Biolegend, USA), anti-IL-17/BV711 (Biolegend ...
• Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks

  Jacob W. Freimer, et al., bioRxiv - Genomics 2021

  Quote: ... or CTLA-4 (Biolegend, Cat #349908). Cells sorted for IL2RA underwent surface staining according to the manufacturer’s protocol ...
• Systematic discovery and perturbation of regulatory genes in human T cells reveals the architecture of immune networks

  Jacob W. Freimer, et al., bioRxiv - Genomics 2021

  Quote: ... or CTLA-4 (Biolegend, Cat #349908) and analyzed with an Attune NxT Flow Cytometer with a 96-well plate-reader.
• Robust SARS-CoV-2-specific T-cell immunity is maintained at 6 months following primary infection

  J Zuo, et al., bioRxiv - Immunology 2020

  Quote: ... and anti-IL-4-PE (Biolegend). All antibodies were purchased from Biolegend ...
• Expression of Tim-3 drives naïve Treg to an effector-like state with enhanced suppressive activity

  Hridesh Banerjee, et al., bioRxiv - Immunology 2020

  Quote: ... CTLA-4 clone UC10-4B9 (BioLegend), CD103 clone M290 (BD) ...
• Acute lymph node slices are a functional model system to study immunity ex vivo

  Maura C. Belanger, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 (ELISA MAX standard, Biolegend) and TNFα (R&D Systems ...
• Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

  Liangxia Ai, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 PE (Biolegend, cat.504104), and IL-5 APC (Biolegend ...
• PPAR-γ regulates the effector function of human T_H9 cells by promoting glycolysis

  Nicole L. Bertschi, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (50 ng/ml) (BioLegend) for TH2 cells ...
• CTLA-4 tail fusion enhances CAR-T anti-tumor immunity

  Xiaoyu Zhou, et al., bioRxiv - Immunology 2023

  Quote: ... or anti-CTLA-4 antibody (Biolegend) at 37°C for 1 hour ...
• Selective Inhibition of Interleukin-2 Inducible T Cell Kinase (ITK) Enhances Anti-Tumor Immunity in Association with Th1-skewing, Cytotoxic T cell Activation, and Reduced T Cell Exhaustion

  Lih-Yun Hsu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-human IL-4 (OA19A66, Biolegend) and anti-human IL-5 (TRFK5 ...
• Diet Induced Obesity and Diabetes Enhance Mortality and Reduces Vaccine Efficacy for SARS-CoV-2

  Robert M Johnson, et al., bioRxiv - Microbiology 2023

  Quote: ... IL-4 BV605 (BioLegend, clone: 11B11), and IL-17a BV711 (BioLegend ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse IL-4 (11B11, Biolegend) and anti-mouse IFNγ (XMG1.2 ...
• Membrane positioning across antigen-induced synaptic contacts tunes CAR-T cell signaling and effector responses

  Fenglei Li, Kaushik Choudhuri, bioRxiv - Immunology 2023

  Quote: ... with 100ng/ml hIL-4 (Biolegend) 2days post transduction ...
• Human cerebrospinal fluid single exosomes in Parkinson’s and Alzheimer’s diseases

  Koya Yakabi, et al., bioRxiv - Neuroscience 2023

  Quote: ... Aquaporin-4 (E5206) (BioLegend catalog #600352), CD11b (M1/70 ...
• A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

  Kristin Metzdorf, et al., bioRxiv - Immunology 2024

  Quote: ... CD11a (M17/4, BioLegend, CA, USA), CD62L (MEL-14 ...
• A rule-based data-informed cellular consensus map of the human mononuclear phagocyte cell space

  Patrick Günther, et al., bioRxiv - Immunology 2019

  Quote: ... Washed cells were incubated with L/D Marker DRAQ7 (BioLegend, USA) for 5 min at room temperature before acquisition and sorting of the cells using a BD FACSARIA III (BD BioSciences ...
• Cytotoxic efficiency of human CD8⁺ T cell memory subtypes

  Arne Knörck, et al., bioRxiv - Immunology 2021

  Quote: ... and PE-conjugated anti-human Perforin antibody (B-D 48, Biolegend) in 0.1% PBS/0.1% saponin ...
• Expression bias in retinoic acid responsive genes defines variations in neural differentiation of human pluripotent stem cells

  Suel-Kee Kim, et al., bioRxiv - Neuroscience 2022

  Quote: ... PAX6 (PRB-278P, BioLegend, 1:500; AF8150, R&D, 1:200), PHOX2B (AF4940 ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and cultured in presence of IL-2 (2 ng/ml; Biolegend), IL-7 (2.5 ng/ml ...
• Protection of bona fide T follicular memory cells during tissue isolation reveals their persistence, plasticity and functional impact

  Marco Künzli, et al., bioRxiv - Immunology 2019

  Quote: ... CD138(BV421, 281-2, BioLegend, #142507; BV711, 281-2, BioLegend, #142519), FAS (PE ...
• Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8⁺ T cells to suppress anti-tumor immunity

  Joanne D. Tejero, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/mL recombinant mouse interleukin-2 (IL-2) (BioLegend); additionally ...
• Non-productive exposure of PBMCs to SARS-CoV-2 induces cell-intrinsic innate immunity responses

  Julia Kazmierski, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-TIM-3/CD366-FITC (#345022; Biolegend). To determine ACE2 cell surface expression ...
• Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μL PE/Cyanine7 anti-IgM(Biolegend, 314532), and fluorophore-labelled Receptor-Binding Domain (RBD ...
• Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μL FITC anti-CD20 Antibody (Biolegend, 302304), 3.5 μL Brilliant Violet 421 anti-CD27 Antibody (Biolegend ...
• Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2021

  Quote: ... 3 μL FITC anti-CD19 Antibody (Biolegend, 392508), 3 μL FITC anti-CD20 Antibody (Biolegend ...
• In vivo analysis of Trypanosoma cruzi persistence foci at single cell resolution

  Alexander I. Ward, et al., bioRxiv - Microbiology 2020

  Quote: ... Antibodies against β-tubulin-3 (Biolegend, Cat#802001), CD45 (Tonbo Biosciences ...
• A P2rx7 passenger mutation affects the vitality and function of immune cells in P2X4ko and other transgenic mice

  Marco Er-Lukowiak, et al., bioRxiv - Immunology 2020

  Quote: ... and recombinant IL-3 (10 ng/ml, Biolegend). BMMCs were transferred into a new petri dish with new BMMC medium every 3-4 days ...
• Overcoming microenvironment-mediated chemoprotection through stromal galectin-3 inhibition in acute lymphoblastic leukemia

  Somayeh S. Tarighat, et al., bioRxiv - Cancer Biology 2021

  Quote: ... and galectin-3 (#125402, Biolegend, San Diego, CA), were diluted 1:1000 or 1:2000 in 5% BSA and incubated for 1hour at room temperature ...
• Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia

  Diego Gilioli, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD223 (LAG-3) BV605 (cat#369324 from BioLegend), CD3 BUV737 (cat#565466 from BD) ...
• Therapy-induced senescence upregulates antigen presentation machinery and triggers anti-tumor immunity in Acute Myeloid Leukemia

  Diego Gilioli, et al., bioRxiv - Cancer Biology 2022

  Quote: ... CD366 (TIM-3) BV421 (cat#345008 from BioLegend), CD223 (LAG-3 ...
• Systematic functional screening of chromatin factors identifies strong lineage and disease dependencies in normal and malignant haematopoiesis

  D Lara-Astiaso, et al., bioRxiv - Genomics 2022

  Quote: ... and CD55 (PE-conjugated; clone RIKO-3; Biolegend). Percent Gran-like (CD11b-high/Gr-1+ ...
• Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance

  Harriet J. Watt, et al., bioRxiv - Immunology 2023

  Quote: ... LAG-3-PE-Cy7 (1:200) (all Biolegend) and TCRβ-BV786 (1:200 ...
• TAD border deletion at the Kit locus causes tissue-specific ectopic activation of a neighboring gene

  Evelyn Kabirova, et al., bioRxiv - Genetics 2022

  Quote: ... and mrIL-3 (10 ng/ml) (Biolegend, 575502). Mast cells were also stained by toluidine blue (Biovitrum ...
• Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging

  Niels Asger Jakobsen, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and propidium iodide (final concentration 3 μM; Biolegend) was used for dead cell exclusion ...
• Rapid activation of IL-2 receptor signaling by CD301b⁺ DC-derived IL-2 dictates the outcome of helper T cell differentiation

  Naoya Tatsumi, et al., bioRxiv - Immunology 2023

  Quote: ... and GATA-3 (16E10A23) were purchased from BioLegend. Anti-pSTAT5 (Tyr694 ...
• Type I interferons sensitise HIV-1-reactivating T-cells for NK cell-mediated elimination despite HDACi-imposed dysregulation of innate immunity

  Julia Prigann, et al., bioRxiv - Microbiology 2023

  Quote: ... and anti-TIM-3/CD366-FITC (#345022; Biolegend). For intracellular immunostaining ...
• Enhancing and inhibitory motifs have coevolved to regulate CD4 activity

  Mark S. Lee, et al., bioRxiv - Immunology 2021

  Quote: ... were coated overnight at 4°C with 8µg of biotinylated anti-CD4 antibody (clone RM4-4, BioLegend). Prior to immunoprecipitation (IP) ...
• Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4⁺ regulatory T cells

  Mark Mensink, et al., bioRxiv - Immunology 2022

  Quote: ... Cell surface expression of CTLA-4 was measured by adding anti-CTLA-4-PE-Dazzle594 mAb (BioLegend) in culture during restimulation for 24 h ...
• The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions

  Mark S. Lee, et al., bioRxiv - Immunology 2023

  Quote: ... were coated overnight at 4°C with 8μg of biotinylated anti-CD4 antibody (clone RM4-4, BioLegend). Prior to immunoprecipitation (IP) ...
• Mouse Memory CD8 T cell subsets defined by Tissue Resident Memory (T_RM) Integrin Expression Exhibit Distinct Metabolic Profiles

  Mike Sportiello, et al., bioRxiv - Immunology 2023

  Quote: ... and plated in TRM-like culture media with 10 ng/mL mouse IL-7 (Biolegend Catalog No. 577804) and 10 ng/mL human TGFβ1 (Fisher Scientific PHG9214 ...
• Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

  Darko Bosnakovski, et al., bioRxiv - Molecular Biology 2023

  Quote: Cells were trypsinized and stained with Annexin V and 7-AAD using APC Annexin V staining kit (BioLegend) according to the manufacturer’s instructions ...
• A Gallium-68-Labeled Peptide Radiotracer For CD38-Targeted Imaging In Multiple Myeloma With PET

  Ajay Kumar Sharma, et al., bioRxiv - Cancer Biology 2023

  Quote: ... cells (1x106) were stained with PE-labelled anti-human CD38 monoclonal antibody (clone HB-7, BioLegend Cat # 356604) in FACS buffer (0.5% FBS with 2 mM EDTA ...
• Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... TRAIL (Biolegend, RIK-2), FasL (Biolegend ...
• The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

  Sumit Sen Santara, et al., bioRxiv - Immunology 2021

  Quote: ... 2 μM monensin (BioLegend) and 3 μM brefeldin A (BD ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 (Biolegend, #431004) and IL-22 (Biolegend ...
• Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

  Rhianna Jones, et al., bioRxiv - Immunology 2021

  Quote: ... CD32 (FUN-2; BioLegend), CD95 (DX2 ...
• Regeneration of humoral immunity from pluripotent stem cells by defined transcription factors

  Qi Zhang, et al., bioRxiv - Immunology 2021

  Quote: ... CD138(281-2, BioLegend), CD38(90 ...
• Deep immune profiling of the maternal-fetal interface with mild SARS-CoV-2 infection

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...