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1 - 50 of 701 citations for 3 Acetoxy 8 17 13E Labdadien 15 Oic Acid since 2020

• Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma

  Eugenia Zah, et al., bioRxiv - Bioengineering 2020

  Quote: ... LAG-3 (eBioscience #17-2239-42 or BioLegend #369314), CD8 (Miltenyi #130-113-164) ...
• Immunisation of ferrets and mice with recombinant SARS-CoV-2 spike protein formulated with Advax-SM adjuvant protects against COVID-19 infection

  Lei Li, et al., bioRxiv - Immunology 2021

  Quote: ... or Interlukin-17 (IL-17) antibodies (BioLegend) according to the manufacturer’s instruction ...
• Circulating Low Density Neutrophils of Breast Cancer Patients are Associated with their Worse Prognosis due to the Impairment of T cell Responses

  Diana P. Saraiva, et al., bioRxiv - Immunology 2021

  Quote: ... IL-17 (Biolegend) and CCL17 (R&D Systems) ...
• Microbiome-derived metabolite effects on intestinal barrier integrity and immune cell response to infection

  Lauren Adams, et al., bioRxiv - Microbiology 2024

  Quote: ... 1L-8 and IL-15 were quantified using individual ELISA kits from (Biolegend), following the manufacturer’s protocol ...
• Protein-based RBD-C-tag COVID-19 Vaccination Candidate Elicits Protection Activity against SARS-COV-2 Variant Infection

  Jaganathan Subramani, et al., bioRxiv - Microbiology 2021

  Quote: ... IL-17 PECy7 (Biolegend, # 506922), donkey anti-mouse IgG conjugated to AlexaFluor 647 (Invitrogen #A-31571 ...
• Arid5a mediates an IL-17-dependent pathway that drives autoimmunity but not antifungal host defense

  Tiffany C. Taylor, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 and IL-17 (Biolegend).
• Mutations in the juxtamembrane segment of the cholesterol-binding site of APP alter its processing and promotes production of shorter, less toxic Aβ peptides

  Linda Hanbouch, et al., bioRxiv - Neuroscience 2020

  Quote: ... and 4G8 (17-24, Biolegend) were added separately to 25 μL of Dynabeads M-280 sheep anti-mouse (ThermoFisher Scientific ...
• Small-molecule degraders reduce Aβ production through CAPRIN1-mediated lysosomal degradation of APP in Alzheimer’s iPSC-derived neurons

  Sunghan Jung, et al., bioRxiv - Neuroscience 2023

  Quote: ... 17-24 (4G8, BioLegend, 800704), Anti-Amyloid Precursor Protein ...
• Platelets are dispensable for the ability of CD8+ T cells to accumulate, patrol, kill and reside in the liver

  James H. O’Connor, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD3 (clone 17.A2- Biolegend). Samples were then resuspended in FACs buffer with viability dye (7-AAD ...
• mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits comparable B cell expansion, neutralizing antibodies and protection against Omicron

  Matthew Gagne, et al., bioRxiv - Immunology 2022

  Quote: ... IL-17 BV605 (clone BL168, BioLegend), IL-21 Ax647 (clone 3A3-N2.1 ...
• Role of T cells in intrauterine administration of activated peripheral blood mononuclear cells in recurrent implantation failure

  Guillaume Ricaud, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL-17/BV711 (Biolegend, USA), anti-AHR/PE Cy7 (Ebioscience ...
• Comparison of Rhesus and Cynomolgus macaques as an authentic model for COVID-19

  Francisco J. Salguero, et al., bioRxiv - Microbiology 2020

  Quote: ... IL-17-BV711 (Biolegend, London, UK) prepared in brilliant stain buffer ...
• Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in nonhuman primates is coincident with an anamnestic antibody response in the lower airway

  Matthew Gagne, et al., bioRxiv - Immunology 2021

  Quote: ... IL-17 BV605 (clone BL168, BioLegend), IL-21 Ax647 (clone 3A3-N2.1 ...
• Multi-scale predictive modeling discovers Ibudilast as a polypharmacological agent to improve hippocampal-dependent spatial learning and memory and mitigate plaque and tangle pathology in a transgenic rat model of Alzheimer’s disease

  Giovanni Oliveros, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: 17-24) (Biolegend – mouse – cat# 800708) and 1:500 for microglia Iba1 (Wako – rabbit – cat# 019-19741) ...
• Protection against SARS-CoV-2 Beta Variant in mRNA-1273 Boosted Nonhuman Primates

  Kizzmekia S. Corbett, et al., bioRxiv - Immunology 2021

  Quote: ... IL-17 BV605 (clone BL168, Biolegend), IL-21 Ax647 (clone 3A3-N2.1 ...
• IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

  Holly Bachus, et al., bioRxiv - Immunology 2022

  Quote: ... and IL-17 (TC11-18H10.1; BioLegend). For pSTAT5 staining of ex vivo CD4+ T cell populations ...
• Durable immunity to SARS-CoV-2 in both lower and upper airways achieved with a gorilla adenovirus (GRAd) S-2P vaccine in non-human primates

  Juan I. Moliva, et al., bioRxiv - Immunology 2023

  Quote: ... IL-17 BV605 (clone BL168, BioLegend), IL-21 Ax647 (clone 3A3-N2.1 ...
• Mucosal Adenoviral-vectored Vaccine Boosting Durably Prevents XBB.1.16 Infection in Nonhuman Primates

  Matthew Gagne, et al., bioRxiv - Immunology 2023

  Quote: ... IL-17 BV605 (clone BL168, BioLegend), IL-21 Ax647 (clone 3A3-N2.1 ...
• Unaltered T cell responses to common antigens in individuals with Parkinson’s disease

  Gregory P. Williams, et al., bioRxiv - Immunology 2022

  Quote: ... IL-17-BV785 (Biolegend, clone BL168, RRID:AB_2566765), TNF-eFluor450 (eBioscience ...
• MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection

  Sharon Khuzwayo, et al., bioRxiv - Immunology 2020

  Quote: ... and anti-IL-17 BV421 (BL168, BioLegend). Cells were PBS washed ...
• Iron-loading is a prominent feature of activated microglia in Alzheimer’s disease patients

  Boyd Kenkhuis, et al., bioRxiv - Neuroscience 2021

  Quote: ... anti-Aβ (17-24) (1:250, Biolegend) and anti-Iba1 (1:20 ...
• Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection

  Paul Ogongo, et al., bioRxiv - Immunology 2024

  Quote: ... and αIL-17 PE clone BL168 (Biolegend). After intracellular staining ...
• Inflammation induced T_h17 cells synergize with the inflammation-trained microbiota to mediate host-resiliency against intestinal injury

  JL Golob, et al., bioRxiv - Immunology 2024

  Quote: ... IL-17 FITC (BioLegend, clone TC11-18H10.1), CD45 BV 605 (BioLegend ...
• Methods for high throughput discovery of fluoroprobes that recognize tau fibril polymorphs

  Emma C. Carroll, et al., bioRxiv - Biochemistry 2024

  Quote: ... 17-24 Antibody clone 4G8 (Biolegend 800702) 1:1000 ...
• Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease

  Gerald Wai-Yeung Cheng, et al., bioRxiv - Neuroscience 2023

  Quote: ... 17-24 Antibody (1:1000, Clone 4G8, N-terminal, a.a. 17-24, human & mouse specific, 800708 BioLegend, CA, USA); Amyloid Precursor Protein (1:1000 ...
• Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection

  Danielle J Smyth, et al., bioRxiv - Immunology 2024

  Quote: Cytokine measurements of serum were performed using LEGENDplex murine Th1/Th2 8 -plex Version 3 (BioLegend) as per kit instructions with data acquired using a Fortessa (BD ...
• Targeting interferon-_λ signaling promotes recovery from central nervous system autoimmunity

  Sindhu Manivasagam, et al., bioRxiv - Immunology 2021

  Quote: ... IL-17 (Clone TC11-18H10.1, BioLegend, Cat 506915), Tbet (Clone 4B10 ...
• Single-cell landscapes of long non-coding RNAs in early vascular endothelial development and hemogenic specification

  Xupeng Chen, et al., bioRxiv - Developmental Biology 2024

  Quote: ... CD44 (17-0441-83, BioLegend, San Diego, CA), CD201 (12-2012-80 ...
• Dissecting the contributions of tumor heterogeneity on metastasis at single-cell resolution

  Juliane Winkler, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 17-5999-82) and anti-human CD298 (PE, BioLegend, 341704). For the Smart-Seq2 experiments ...
• Soluble CTLA-4 mainly produced by Treg cells inhibits type 1 inflammation without hindering type 2 immunity to allow for inflammation resolution

  Motonao Osaki, Shimon Sakaguchi, bioRxiv - Immunology 2023

  Quote: ... anti-mCD38 (90, eBioscience, 17-0381-82, or BioLegend, 102714), anti-h/mGL-7 (GL-7 ...
• Commensal Bacteria Maintain a Qa-1^b-restricted Unconventional CD8⁺ T Population in Gut Epithelium

  Jian Guan, et al., bioRxiv - Immunology 2023

  Quote: ... 106 of the CTV labeled T cells were stimulated in vitro for 3 or 5 days in cultures containing 100ng/ml IL-15 (BioLegend) or a combination of 100ng/ml IL-7 (BioLegend ...
• Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells

  Ellen J.K. Xu, et al., bioRxiv - Immunology 2024

  Quote: ... Staining was performed by washing with 0.1% Triton-X 100 in PBS for 3 x 15 minutes then staining for CD3-PE (1:100, Biolegend, 100205) overnight at room temp ...
• Single nuclear transcriptional signatures of dysfunctional brain vascular homeostasis in Alzheimer’s disease

  Stergios Tsartsalis, et al., bioRxiv - Neuroscience 2021

  Quote: ... AD pathology was assessed by Aβ plaque (4G8, BioLegend 17-24) and pTau (AT8 ...
• Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology

  Amy M. Smith, et al., bioRxiv - Neuroscience 2021

  Quote: ... AD pathology was assessed by amyloid plaque (4G8, BioLegend 17-24) and pTau (AT8 ...
• A multi-enhancer hub at the Ets1 locus controls T cell differentiation and allergic inflammation through 3D genome topology

  Aditi Chandra, et al., bioRxiv - Genomics 2022

  Quote: ... anti-mouse IL-17 PE (clone TC11-18H10.1, BioLegend, Cat# 506903), anti-mouse RORgt BV421 (BD Biosciences Cat#562894) ...
• Social Determinants modulate NK cell activity via obesity, LDL, and DUSP1 signaling

  Yvonne Baumer, et al., bioRxiv - Immunology 2023

  Quote: To determine galectin-3 or galectin-8 expression the following: intracellular protein and lysosomes were stained using anti-Lamp1-BV421 (clone H4A3, BioLegend, USA), anti-Galectin-3-AF488 (clone B2C10 ...
• Steady-state, therapeutic, and helminth-induced IL-4 compromise protective CD8 T cell bystander activation

  Nicholas J Maurice, et al., bioRxiv - Immunology 2024

  Quote: ... rIL-15 (BioLegend), and/or rIL-18 (BioLegend ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... NKp44 (Biolegend, P44-8), NKG2D (Biolegend ...
• The first transchromosomic rat model with human chromosome 21 shows robust Down syndrome features

  Yasuhiro Kazuki, et al., bioRxiv - Genetics 2021

  Quote: ... CD8a (OX-8, Biolegend) and CD45R (HIS24 ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... NKp30 (Biolegend, P30-15), NKp44 (Biolegend ...
• Integration of Avidity and Differentiation is enabled by CD8⁺ T-cell sensing of IFN-γ

  Lion F.K. Uhl, et al., bioRxiv - Immunology 2023

  Quote: ... IL-15 (Biolegend, #566302), TNF (PeproTech ...
• The CARD8 inflammasome drives CD4⁺ T-cell depletion in HIV-1 infection

  Qiankun Wang, Liang Shan, bioRxiv - Microbiology 2023

  Quote: ... IL-15 (BioLegend #570306), SCF (STEMCELL Technologies #78062) ...
• The antimicrobial peptide cathelicidin is critical for the development of Th17 responses in severe inflammatory disease

  Katie J Smith, et al., bioRxiv - Immunology 2022

  Quote: ... RORγT (B2D, eBioscience, #17-6981-80, 1:100) CD121a (JAMA-147, Biolegend, #113509)
• SARS-CoV-2 infection leads to acute infection with dynamic cellular and inflammatory flux in the lung that varies across nonhuman primate species

  Dhiraj Kumar Singh, et al., bioRxiv - Immunology 2020

  Quote: ... IL-17 (clone BL168) and PD-1 (clone EH12.2H7) were purchased from BioLegend, San Diego ...
• Post-Translational Modifications Control Phase Transitions of Tau

  Wyatt C. Powell, et al., bioRxiv - Biophysics 2024

  Quote: ... 15-25 mouse antibody (binds residues 15-25 on 2N4R Tau, BioLegend, 835201) as the primary antibody instead of mAb 423 ...
• Effects of bacterial lipopolysaccharide and Shiga Toxin on induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells

  Daiana Martire-Greco, et al., bioRxiv - Immunology 2021

  Quote: ... IL-8 (BioLegend cat. 78141), TGF-β (Biolegend ...
• Reticular Dysgenesis-associated Adenylate Kinase 2 deficiency causes failure of myelopoiesis through disordered purine metabolism

  Wenqing Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... siglet-8 APC (Biolegend 347105), HLA-DR APC-R700 (BD 565127) ...
• Dose range-finding toxicity study in rats with recombinant human lactoferrin produced in Komagataella phaffii

  Ross Peterson, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... CD8 (clone OX-8) (Biolegend) and CD25 (clone OX-39 ...
• Myelin-reactive B cells exacerbate the severity of CD4⁺ T cell-driven CNS autoimmunity in an IL-23-dependent manner.

  Mohamed Reda Fazazi, et al., bioRxiv - Immunology 2023

  Quote: ... clone 39-10-8 (Biolegend); IFN-γ ...
• Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction and cellular dNTP levels

  Moritz Schüssler, et al., bioRxiv - Microbiology 2023

  Quote: ... CCR5-PE (T21/8, Biolegend) or respective isotype controls (Biolegend ...