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401 - 450 of 7756 citations for 1 Benzyl 3 Tert Butyldimethylsilyl Oxy Methyl Piperidin 4 One since 2020

• STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

  Yulin Wang, et al., bioRxiv - Immunology 2022

  Quote: ... and 4 μg/ml CD49b PeCy7 (BioLegend) in 30 μl PBS for 30 minutes at 37°C ...
• Multi-omic QTL mapping in early developmental tissues reveals phenotypic and temporal complexity of regulatory variants underlying GWAS loci

  Timothy D. Arthur, et al., bioRxiv - Genomics 2024

  Quote: ... and SSEA-4 (PE anti-human, Biolegend). Pluripotency was also examined using PluriTest-RNAseq47.
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-CTLA-4 (APC, clone BNI3 – BioLegend), anti-CD137 (APC-Cy-7 ...
• Mechanical activation of TWIK-related potassium channel by nanoscopic movement and rapid second messenger signaling

  E. Nicholas Petersen, et al., bioRxiv - Neuroscience 2023

  Quote: ... 4 ug/mL apolipoprotein E3 (BioLegend, USA) was mixed with fresh 10% FBS and applied to the cells for 1hr prior to shear and or fixing.
• Cellular iron governs the host response to malaria

  Sarah K. Wideman, et al., bioRxiv - Immunology 2023

  Quote: ... 10 ng/mL IL-4 (574302, BioLegend), 10 ng/mL IL-5 (581502 ...
• Dendritic cell-mediated responses to secreted Cryptosporidium effectors are required for parasite-specific CD8⁺ T cell responses

  Breanne E. Haskins, et al., bioRxiv - Immunology 2023

  Quote: ... CD11a PE (clone M17/4) from Biolegend; CD90.1 APC-ef780 (clone HIS51) ...
• A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint

  Graham A. Heieis, et al., bioRxiv - Immunology 2023

  Quote: ... 1ug/ml αIL-4 (UBC Ablab/BioLegend); or Th2 ...
• CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

  Ian E. Prise, et al., bioRxiv - Immunology 2023

  Quote: ... rat anti-Tim-4 (RMT4-54, BioLegend) or rabbit anti-CD163 (ab182422 ...
• CD163 and Tim-4 identify resident intestinal macrophages across sub-tissular regions that are spatially regulated by TGF-β

  Ian E. Prise, et al., bioRxiv - Immunology 2023

  Quote: ... and Tim-4 (RMT4-54) from BioLegend as well as CD163 (TNKUPJ ...
• A PD-1-ST2 axis controls Th2 effector function in tissue via a metabolic checkpoint

  Graham A. Heieis, et al., bioRxiv - Immunology 2023

  Quote: ... IL-4 (11B11) conjugated to BV421 (BioLegend); IL-5 (TRFK5 ...
• BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine

  Dilhan J. Perera, et al., bioRxiv - Immunology 2023

  Quote: ... IL-4-BV421 (11B11, RRID: AB_2562594, BioLegend), GrB-PE (QA1602 ...
• A viral-specific CD4⁺ T cell response protects female mice from Coxsackievirus B3 infection

  Aryamav Pattnaik, et al., bioRxiv - Immunology 2023

  Quote: ... CD11a (clone M17/4, BioLegend, catalog # 101106), CD62L (clone MEL-14 ...
• eQTL mapping in fetal-like pancreatic progenitor cells reveals early developmental insights into diabetes risk

  Jennifer P. Nguyen, et al., bioRxiv - Genomics 2023

  Quote: ... and SSEA-4 (PE anti-human, Biolegend) 35 ...
• Analysis of regulatory network modules in hundreds of human stem cell lines reveals complex epigenetic and genetic factors contribute to pluripotency state differences between subpopulations

  Timothy D. Arthur, et al., bioRxiv - Genomics 2023

  Quote: ... and SSEA-4 (PE anti-human, Biolegend). Pluripotency was also examined using PluriTest-RNAseq 70 ...
• Suppression of autoimmune arthritis and neuroinflammation via an amino acid-conjugated butyrate prodrug with enhanced oral bioavailability

  Shijie Cao, et al., bioRxiv - Bioengineering 2023

  Quote: ... CTLA-4 (PE-Cy7, Cat#106314, Biolegend), CD25 (APC ...
• Bone marrow by day, lymph nodes by night: Undernutrition imparts a distinct circadian rhythm to T cells in mice

  Takesha R. Foster, et al., bioRxiv - Immunology 2024

  Quote: ... naïve (CD62L (MEL-4, Biolegend, California, USA) and/or CD44 (IM7 ...
• Increasing Signal Intensity of Fluorescent Oligo-Labeled Antibodies to Enable Combination Multiplexing

  Madeline E. McCarthy, et al., bioRxiv - Molecular Biology 2024

  Quote: ... (4) CD3 (clone UCHT1; Biolegend Cat: 300402) labeled with Atto647 int ...
• Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

  Mikala C. Mueller, et al., bioRxiv - Bioengineering 2024

  Quote: ... 4′,6-diamidino-2-phenylindole (DAPI; BioLegend) was diluted 1:10,000 from a 5 mg mL-1 stock solution in deionized water ...
• Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates Macrophage Polarization in Relapsed Melanoma

  Rotem Leshem, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and CTLA-4 (Cat. 106338) from Biolegend. Tox (Cat ...
• SUMO Inhibition Plus CD40 Agonism Increases Anti-Tumor Immunogenicity Through Interferon Mediated Macrophage Activation

  Kevin Li, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Anti-CTLA-4 (Biolegend, Clone: UC10-4B9), Anti-CD3 (Biolegend ...
• Species- and strain-effects in interferon, innate immunity, and barrier transcriptional response of microbiome interactions of 3D respiratory epithelial cultures

  Mian Horvath, et al., bioRxiv - Microbiology 2023

  Quote: ... for one hour followed by secondary antibody (anti-rabbit IgG AF555, #406412, BioLegend, San Diego, CA, USA) for 30 min at room temperature in 1X PBS/5% BSA/0.05% saponin ...
• Single-Molecule Barcoding Technology for Single-Cell Genomics

  Ivan Garcia-Bassets, et al., bioRxiv - Molecular Biology 2024

  Quote: ... One million PBMCs (typically > 95% viable) were resuspended in 45 µL cell staining buffer (BioLegend, Cat#420201), and 5 uL of Human TruStain FcX Fc Blocking reagent (BioLengend ...
• The circadian gene Dec2 promotes pancreatic cancer dormancy by regulating tumor cell antigen presentation to facilitate immune evasion

  Chris R. Harris, et al., bioRxiv - Cancer Biology 2024

  Quote: ... One million cells were resuspended in 100 μl FACS buffer and blocked with TruStain FcX antibody (Biolegend) at 100x dilution at 4 °C for 10 minutes ...
• Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritis

  Ping Wang, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD28 and anti-CD40 (3 μg/mL, Biolegend) in a round-bottom 96-well plate ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma

  Eugenia Zah, et al., bioRxiv - Bioengineering 2020

  Quote: ... LAG-3 (eBioscience #17-2239-42 or BioLegend #369314), CD8 (Miltenyi #130-113-164) ...
• SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8

  Valentina Salvi, et al., bioRxiv - Immunology 2021

  Quote: ... FITC-conjugated anti-mouse CD40 (clone HM40-3, Biolegend) and APC-CY7-conjugated anti-mouse CD86 (clone GL-1 ...
• Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

  Ning Yang, et al., bioRxiv - Microbiology 2021

  Quote: ... and stained with antibodies against CD40 (3/23, Biolegend) and CD86 (GL-1 ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... with 3 μl of Annexin-V-APC (640941, BioLegend) and DAPI (200 ng/ml) ...
• Circulating levels of epirubicin cause endothelial senescence while compromising metabolic activity and vascular function

  Amanda J Eakin, et al., bioRxiv - Cell Biology 2020

  Quote: ... rat anti-mouse Mac-2 (Galectin-3, 125402, Biolegend) for myeloid cells (Ho and Springer 1982) ...
• Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease

  Adriaan van der Graaf, et al., bioRxiv - Genetics 2020

  Quote: ... or IL-21 (3 ng/ml, Biolegend, cat 571204) (n=8 samples per condition ...
• A microbiota-derived metabolite instructs peripheral efferocytosis

  Pedro H. V. Saavedra, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml recombinant annexin V (BioLegend, 640901) for 1 hour at 4 °C ...
• Type 1 interferon remodels normal and neoplastic hematopoiesis in human

  Chhiring Lama, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 2 or 3 (TotalSeq-A, clone LNH-94, Biolegend) for GoT-IM ...
• Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

  Aidan M. Tousley, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... TIM-3 (BV510 or BV650, Clone F38-2E2, BioLegend), LAG-3 (PE ...
• FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats

  Peter Aldiss, et al., bioRxiv - Physiology 2024

  Quote: ... anti-galectin-3 (cat. 125402, Biolegend, San Diego, CA), alpha-smooth muscle action (α-SMA ...
• Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1⁺ macrophages

  Jiangyan Yu, et al., bioRxiv - Immunology 2023

  Quote: ... Then cells were stained with CCR7 (3:100, BioLegend) and CADM1 (2:100 ...
• PP2A catalytic subunit alpha is critically required for CD8⁺ T cell homeostasis and anti-bacterial responses

  Xian Zhou, et al., bioRxiv - Immunology 2024

  Quote: ... Alexa fluor 700-labeled anti-CD8β (Lyt-3; Biolegend), BV650-labeled anti-CD45.1 (Ly5.1 ...
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• MiR-324-5p regulates the structure of dendritic spines and is essential for hippocampal long-term potentiation

  Emma V Parkins, et al., bioRxiv - Neuroscience 2023

  Quote: ... Beta 3 tubulin rabbit polyclonal (BioLegend Cat# 802001, RRID:AB_2564645), Anti-PSD-95 MAGUK scaffold protein mouse monoclonal (Antibodies Incorporated Cat# 75-348 ...
• Broad-spectrum RNA antiviral inspired by ISG15^-/- deficiency

  Yemsratch T. Akalu, et al., bioRxiv - Immunology 2024

  Quote: ... or with anti-cleaved caspase-3 antibody (Biolegend 559341) for quantification by flow cytometry.
• Human effector CD8⁺ T cells with an exhausted-like phenotype control tumor growth in vivo in a humanized tumor model

  Juliane Mietz, et al., bioRxiv - Immunology 2024

  Quote: ... Galectin-9-PE-Cy7 (Biolegend, 9M1-3, Cat. 348916), TIGIT-APC-Cy7 (Biolegend ...
• LAG-3 blockade reactivates the CD8⁺ T cell expansion program to re-expand contracted clones in the tumor

  Munetomo Takahashi, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-LAG-3 (clone C9B7W, BioLegend or Selleck) was injected intraperitoneally at a dose of 200 μg per mouse on days 14 and 16 (for bulk RNA-seq data ...
• Cancer-associated adipocytes mediate CD8⁺T cell dysfunction via FGF21-driven lipolysis

  Sumiya Dalangood, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-TIM-3-PE/Cy7 (cat#134009, CloneB8.2C12, Biolegend), anti-LAG3-Percp/Cyanine5.5 (cat#125211 ...
• Catabolism of extracellular glutathione supplies amino acids to support tumor growth

  Fabio Hecht, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 3 µL of Annexin V-FITC (Biolegend 0640906). Then ...
• Epithelial-mesenchymal transition is the main driver of intrinsic metabolism in cancer cell lines

  Sarah Cherkaoui, et al., bioRxiv - Systems Biology 2021

  Quote: Cells were stained overnight at 4°C in blocking solution with the following antibodies: AlexaFluor® 488 anti-Vimentin (1:1000, Biolegend, #677809), AlexaFluor® E-cadherin (1:200 ...
• Nanoscale organization of the endogenous ASC speck

  Ivo M. Glück, et al., bioRxiv - Immunology 2022

  Quote: ... cells were incubated overnight at 4°C with purified monoclonal mouse anti-human ASC antibodies (TMS-1) (clone HASC-71) (Biolegend, California, USA) at a final concentration of 10 µg/ml diluted in 10% NGS + 0.5% Triton X-100 in PBS ...
• Urinary single-cell sequencing captures intrarenal injury and repair processes in human acute kidney injury

  Jan Klocke, et al., bioRxiv - Molecular Biology 2022

  Quote: ... samples P008-016 and P048-119 (Suppl. Fig. 4D) were labelled with TotalSeq B Hashtag antibodies 1-4 (Biolegend, clone LNH-94) during the staining procedure described above and pooled in groups of four.
• GZMK^high CD8⁺ T effector memory cells are associated with CD15^high neutrophil abundance in early-stage colorectal tumors and predict poor clinical outcome

  Silvia Tiberti, et al., bioRxiv - Immunology 2021

  Quote: ... Slides were incubated ON at 4°C with mouse anti-human CD66b antibody (BioLegend, 305102, 1:100 for both IHC and IF), anti-human CD8 (Invitrogen ...
• Spermidine/spermine N1-acetyltransferase controls tissue-specific regulatory T cell function in chronic inflammation

  Teresa Neuwirth, et al., bioRxiv - Immunology 2024

  Quote: ... Cells were harvested and stained for 30min at 4°C with the following antibodies: anti-CD25 BV785 (Biolegend, Cat: 356139, 1:50), anti-CD127 PE (Biolegend ...
• The Benchtop mesoSPIM: a next-generation open-source light-sheet microscope for large cleared samples

  Nikita Vladimirov, et al., bioRxiv - Neuroscience 2023

  Quote: ... and incubated 72h at 4°C on a rotating wheel with the secondary antibody (1:500, Alexa-Fluor-555, 405324 P4U/BioLegend UK Ltd) diluted in 100% CAS-Block ...