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351 - 400 of 2808 citations for 3 2 5 Dioxoimidazolidin 4 yl propanoic acid since 2020

• Dose range-finding toxicity study in rats with recombinant human lactoferrin produced in Komagataella phaffii

  Ross Peterson, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... CD11b (clone WT.5) (Biolegend), CD25 (clone OX-39 ...
• Dynamic fibroblast-immune interactions shape wound healing after brain injury

  Nathan A. Ewing-Crystal, et al., bioRxiv - Immunology 2024

  Quote: ... anti-CD4 (RM4-5, Biolegend 100557 ...
• Electrostatic-driven Interactions Enhance Intratumoral Retention and Antitumor Efficacy of Immune Checkpoint Blockade Antibodies

  Rashmi P Mohanty, et al., bioRxiv - Bioengineering 2023

  Quote: ... CD4 (RM4-5, #100511, BioLegend), CD8 (53-6.7 ...
• Type I IFN signaling mediates NET release to promote Mycobacterium tuberculosis replication and granuloma caseation

  Chanchal Sur Chowdhury, et al., bioRxiv - Microbiology 2022

  Quote: ... CD4 (clone RM4-5; BioLegend), TCRβ (clone H57-567 ...
• RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection

  Marissa Lindman, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (Biolegend, clone RM4-5), CD45.2 (Biolegend ...
• A role for BCL6 in maintaining CX3CR1⁺ CD4⁺ T cells during helminth infection

  Denis G. Loredan, et al., bioRxiv - Immunology 2023

  Quote: ... IL-5 APC (TRFK5, BioLegend), GATA3 PerCP-Cyanine5.5 (16E10A23 ...
• An exosome-based gene delivery platform for cell-specific CRISPR/Cas9 genome editing

  Sunil Dubey, et al., bioRxiv - Molecular Biology 2023

  Quote: ... CD4 (BV605, RM4-5, BioLegend), NK-1.1 (Brilliant Violet 650 ...
• Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease-like ileitis

  Weili Xu, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD4 (RM4-5, Biolegend), anti-CD8α (53-6.7 ...
• Soluble CTLA-4 mainly produced by Treg cells inhibits type 1 inflammation without hindering type 2 immunity to allow for inflammation resolution

  Motonao Osaki, Shimon Sakaguchi, bioRxiv - Immunology 2023

  Quote: ... anti-mCD4 (RM4-5, BioLegend, 100548 or 100550 ...
• Oncostatin M is a Master Regulator of an Inflammatory Network in Dnmt3a-Mutant Hematopoietic Stem Cells

  Logan S. Schwartz, et al., bioRxiv - Cell Biology 2023

  Quote: ... CD4 (BioLegend clone RM4-5), CD5 (BioLegend clone 53-7.3) ...
• Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

  Jiang Li, et al., bioRxiv - Immunology 2023

  Quote: ... CD64 (X54-5/7.1, Biolegend), RELMα (DS8RELM ...
• Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis

  Julia Sbierski-Kind, et al., bioRxiv - Immunology 2023

  Quote: ... anti-CD4 (RM4-5, Biolegend), anti-CD8 (53-6.7 Biolegend) ...
• Attenuated Mycobacterium tuberculosis Vaccine Protection in a Low Dose Murine Challenge Model

  Samuel J. Vidal, et al., bioRxiv - Microbiology 2023

  Quote: ... CD4 (clone RM4-5, BioLegend), CD8a (clone 53-6.7 ...
• Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis

  Marisol Alvarez-Martinez, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, BV785, Biolegend), TCR-β (H57-597 ...
• Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis

  Marisol Alvarez-Martinez, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, BV785, Biolegend), TCR-β (H57-597 ...
• Astrocytic RIPK3 exerts protective anti-inflammatory activity during viral encephalitis via induction of serpin protease inhibitors

  Marissa Lindman, et al., bioRxiv - Immunology 2024

  Quote: ... CD4 (Biolegend, clone RM4–5), CD45.2 (Biolegend ...
• Characterization of Collaborative Cross mouse founder strain CAST/EiJ as a novel model for lethal COVID-19

  Candice N. Baker, et al., bioRxiv - Immunology 2024

  Quote: ... CD64 (X54-5/7.1) (Biolegend); CD335 (29A1.4) ...
• Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells

  Joshua B. Perkins, et al., bioRxiv - Immunology 2024

  Quote: ... CD64 (X54-5/7.1, BioLegend), CD24 (M1/69 ...
• Polyphosphate mobilization influences the ability of Cryptococcus neoformans to cause disease in a murine model of cryptococcosis

  Kabir Bhalla, et al., bioRxiv - Microbiology 2024

  Quote: ... CD4 (RM4-5) from BioLegend; NK1.1 (PK136) ...
• Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis

  Gabriela Pessenda, et al., bioRxiv - Immunology 2024

  Quote: ... CD64 (X54-5/7.1, Biolegend) 1:200 ...
• 4-week GLP immunotoxicity assessment of lactoferrin alpha produced by Komagataella phaffii in Sprague Dawley rats

  Ross Peterson, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... CD11b (clone WT.5) (Biolegend), CD25 (clone OX-39 ...
• Enhancing and inhibitory motifs have coevolved to regulate CD4 activity

  Mark S. Lee, et al., bioRxiv - Immunology 2021

  Quote: ... were coated overnight at 4°C with 8µg of biotinylated anti-CD4 antibody (clone RM4-4, BioLegend). Prior to immunoprecipitation (IP) ...
• Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4⁺ regulatory T cells

  Mark Mensink, et al., bioRxiv - Immunology 2022

  Quote: ... Cell surface expression of CTLA-4 was measured by adding anti-CTLA-4-PE-Dazzle594 mAb (BioLegend) in culture during restimulation for 24 h ...
• The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-LCK interactions

  Mark S. Lee, et al., bioRxiv - Immunology 2023

  Quote: ... were coated overnight at 4°C with 8μg of biotinylated anti-CD4 antibody (clone RM4-4, BioLegend). Prior to immunoprecipitation (IP) ...
• Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... TRAIL (Biolegend, RIK-2), FasL (Biolegend ...
• The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

  Sumit Sen Santara, et al., bioRxiv - Immunology 2021

  Quote: ... 2 μM monensin (BioLegend) and 3 μM brefeldin A (BD ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 (Biolegend, #431004) and IL-22 (Biolegend ...
• Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

  Rhianna Jones, et al., bioRxiv - Immunology 2021

  Quote: ... CD32 (FUN-2; BioLegend), CD95 (DX2 ...
• Regeneration of humoral immunity from pluripotent stem cells by defined transcription factors

  Qi Zhang, et al., bioRxiv - Immunology 2021

  Quote: ... CD138(281-2, BioLegend), CD38(90 ...
• Deep immune profiling of the maternal-fetal interface with mild SARS-CoV-2 infection

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Circulating mast cell progenitors migrate to atopic dermatitis-like skin then adapt locally

  Yuki Honda Keith, et al., bioRxiv - Immunology 2022

  Quote: ... integrinβ2 (M18/2; BioLegend), IgE (R35-72 ...
• Integration of Avidity and Differentiation is enabled by CD8⁺ T-cell sensing of IFN-γ

  Lion F.K. Uhl, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend, #575404), IL-1β (Biolegend ...
• Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

  Lucy Cooper, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 (Biolegend #155863) for 20 minutes at 4°C ...
• Novel Fas-TNFR chimeras that prevents Fas ligand-mediated kill and signals synergistically to enhance CAR T-cell efficacy

  Callum McKenzie, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... IL-2 (Biolegend; 431804), CCL1 (R&D Systems ...
• Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-T_SCM cells using qCART, the Quantum pBac-based CAR-T system

  Peter S. Chang, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and IL-2 (BioLegend) were quantified by ELISA according to manufacturer’s instructions.
• Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

  Yuhao Shi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD8b.2 (Biolegend, 140416), Granzyme B (Biolegend ...
• Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells

  Joshua B. Perkins, et al., bioRxiv - Immunology 2024

  Quote: ... CD8a (Ly-2, BioLegend), and CCR6 (29-2L17 ...
• Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation

  Hrishikesh S. Kulkarni, et al., bioRxiv - Immunology 2024

  Quote: ... CD138 (281-2; Biolegend) CD38 (S21016F ...
• Macrophage-Based iNos Reporter Reveals Polarization and Reprogramming in the Context of Breast Cancer

  Javier A. Mas-Rosario, et al., bioRxiv - Immunology 2022

  Quote: ... culture media was removed and replaced with media containing either 50 ng/mL interleukin 4 (IL-4) (BioLegend) for 48 hr to generate M2 macrophages or 50 ng/mL interferon-gamma (IFN-γ ...
• Soluble CTLA-4 raises the threshold for T-cell activation and modulates anti-tumour immunity

  Paul T. Kennedy, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and supplemented with sCTLA-4 conditioned media or murine CTLA-4-Fc fusion protein (10 µg/mL, BioLegend). After 4 days ...
• Progenitor identification and SARS-CoV-2 infection in long-term human distal lung organoid cultures

  Ameen A. Salahudeen, et al., bioRxiv - Cell Biology 2020

  Quote: ... Mouse anti-TNFRSF12A (clone ITEM-4, Biolegend) was utilized for (Fig ...
• Synergistic activity of Nanog, Pou5f3, and Sox19b establishes chromatin accessibility and developmental competence in a context-dependent manner

  Liyun Miao, et al., bioRxiv - Developmental Biology 2020

  Quote: ... 4 µg of anti-RNA polymerase II CTD repeat YSPTSPS antibody [8WG16] from Abcam (ab817) and 4 µg from BioLegend (664912) were used for each sample ...
• Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells

  Ofer Guttman, et al., bioRxiv - Cell Biology 2021

  Quote: ... and 10 ng/ml IL-4 (Biolegend) for 9 days ...
• Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue Resident Memory T cell During H5N1 infection

  Matheswaran Kandasamy, et al., bioRxiv - Microbiology 2020

  Quote: ... anti-CD4 (2µg/ml, RM4-4; Biolegend), anti-CD3 (2µg/ml ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CTLA-4 (APC, clone BNI3 – BioLegend), anti-CD138 (APC-Cy-7 ...
• Heterotypic Influenza Infections Mitigate Susceptibility to Secondary Bacterial Infection

  Ellyse M. Cipolla, et al., bioRxiv - Immunology 2022

  Quote: ... Cd11a (M17/4,BioLegend, San Diego, CA), Cd127 (SB/199,Invitrogen-ThermoFisher Scientific ...
• Vaccine Elicitation of HIV Broadly Neutralizing Antibodies from Engineered B cells

  Deli Huang, et al., bioRxiv - Immunology 2020

  Quote: ... IL-4 at 50ng/ml(Biolegend, #574306), anti-CD40 at 5 μg/ml (Thermo ...
• Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates

  Lochana M. Seenappa, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (PE, clone: 8D4-8, BioLegend), TNFα (BV605 ...
• Differential Nr4a1 and Nr4a3 expression discriminates tonic from activated TCR signalling events in vivo

  Emma Jennings, et al., bioRxiv - Immunology 2020

  Quote: ... TCRVβ5.1/5.2 APC (Clone MR9-4, BioLegend), B220 PerCPcy5.5 (Clone RA3-6B2 ...