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3001 - 3050 of 5512 citations for Recombinant Human APCS Protein since 2019

• CD4⁺ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

  Viviana Rubino, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 100 ng/ml recombinant mouse (rm)-SCF (Miltenyi) and 20 ng/ml rm-TPO (BioLegend), in the presence or absence of 300 pg/ml rm-IL21 (R&D Systems) ...
• CD4⁺ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

  Viviana Rubino, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 100 ng/ml recombinant mouse (rm)-SCF (Miltenyi) and 20 ng/ml rm-TPO (BioLegend), in the presence or absence of 300 pg/ml rm-IL21 (R&D Systems) ...
• γδ T cells are effectors of immune checkpoint blockade in mismatch repair-deficient colon cancers with antigen presentation defects

  Natasja L. de Vries, et al., bioRxiv - Cancer Biology 2021

  Quote: ... incubated with human Fc receptor block (BioLegend), and stained with cell surface antibodies (1:100 anti-CD137-APC [clone 4B4-1 ...
• A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia

  Richard A. Voit, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-human CD34-Alexa 488 (Biolegend, 343518) and anti-human CD235a-APC (Ebioscience ...
• A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia

  Richard A. Voit, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-human CD3-Pacific Blue (Biolegend, 344823), anti-human CD19-PECy7 (Biolegend ...
• Neuroprotection in early stages of Alzheimer’s Disease is promoted by Transthyretin angiogenic properties

  Tiago Gião, et al., bioRxiv - Molecular Biology 2021

  Quote: ... using the LEGENDplex Human Angiogenesis Panel (BioLegend) bead-based immunoassay ...
• Single-cell analysis of skeletal muscle macrophages reveals age-associated functional subpopulations

  Linda K. Krasniewski, et al., bioRxiv - Cell Biology 2022

  Quote: ... PE anti-mouse/human CD11b Antibody (Biolegend, Cat# 101208 ...
• Holistic Characterization of Tumor Monocyte-to-Macrophage Differentiation Integrates Distinct Immune Phenotypes in Kidney Cancer

  Adriana M. Mujal, et al., bioRxiv - Immunology 2021

  Quote: Cells were incubated with Human FcX (Biolegend) to prevent non-specific antibody binding ...
• Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

  Maya Imbrechts, et al., bioRxiv - Immunology 2021

  Quote: ... FITC anti-human CD3 antibody (Biolegend, 300306) and PE streptavidin (Biolegend ...
• Engineered niches support the development of human dendritic cells in humanized mice

  Giorgio Anselmi, et al., bioRxiv - Immunology 2019

  Quote: ... and mouse anti-human CD45 (HI30, Biolegend) overnight followed by 1hr incubation at room temperature with goat anti-mouse Cy3 (Jackson laboratory ...
• Variation of immune cell responses in humans reveals sex-specific coordinated signaling across cell types

  Gabriela K. Fragiadakis, et al., bioRxiv - Immunology 2019

  Quote: ... blocked with human TruStain FcX block (Biolegend) for 10 minutes at room temperature with shaking ...
• Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

  S. Jordan Kerns, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-human-CD8-PE/Dazzle-594 (BioLegend), and anti-human CD69 APC (BioLegend).
• Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies

  S. Jordan Kerns, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-human CD4 Brilliant Violet 786 (BioLegend), anti-human-CD8-PE/Dazzle-594 (BioLegend) ...
• SARS-CoV-2 variant B.1.1.7 caused HLA-A2⁺ CD8⁺ T cell epitope mutations for impaired cellular immune response

  Chanchan Xiao, et al., bioRxiv - Immunology 2021

  Quote: ... and FITC anti-human Granzyme B (BioLegend) staining.
• The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC

  Aaron Javitt, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse/human CD44-FITC (IM7, Biolegend 103005), FC ...
• TIGIT-Fc Promotes Antitumour Immunity

  Wenyan Fu, Changhai Lei, Jian Zhao, Shi Hu, bioRxiv - Bioengineering 2020

  Quote: ... and antibodies to human CD3 (HIT3a, BioLegend), CD45 (2D1 ...
• A high throughput bispecific antibody discovery pipeline

  Aude I. Segaliny, et al., bioRxiv - Bioengineering 2021

  Quote: ... FITC-anti human CD25 antibody (#356106, Biolegend), APC anti-human CD279 antibody (#329908 ...
• A high throughput bispecific antibody discovery pipeline

  Aude I. Segaliny, et al., bioRxiv - Bioengineering 2021

  Quote: ... PE-anti human CD69 antibody (#310906, Biolegend), FITC-anti human CD25 antibody (#356106 ...
• Control of Neutrophil activation through Semaphorin 7A-Plexin C1 is essential for immune defense during pulmonary sepsis

  Tiago Granja, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-human LFA1 (CD11a) FITC (Biolegend 363404) and anti-human PSGL1 BV421 (BD # 563961 ...
• Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detection

  Nikhil Ram-Mohan, et al., bioRxiv - Immunology 2020

  Quote: ... mouse anti-human PerCPcy5.5-CD66b (Biolegend # 305107), and mouse anti-human V500-CD45 (BD # 560779 ...
• Aged Breast Extracellular Matrix Drives Mammary Epithelial Cells to an Invasive and Cancer-Like Phenotype

  Gokhan Bahcecioglu, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 0.3 μL human hashtag (HTO) antibody (Biolegend) was added to each sample (a different hashtag antibody was used for each sample/replicate ...
• Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies

  Abdullah O. Khan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-human CD34 (BioLegend Cat# 343502, RRID:AB_1731898), polyclonal VE-Cadherin (Thermo Fisher Scientific Cat# 36-1900 ...
• Multivalent, Bispecific αB7-H3-αCD3 Chemically Self-Assembled Nanorings Direct Potent T-cell Responses Against Medulloblastoma

  Ellie A. Mews, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-human CCR7 (Biolegend, clone G043H7, AF647), and anti-human CD45RO (Biolegend ...
• Distinct gene expression by expanded clones of quiescent memory CD4⁺ T cells harboring intact latent HIV-1 proviruses

  Georg H J Weymar, et al., bioRxiv - Immunology 2022

  Quote: ... PacificBlue anti-human CD3 (BioLegend, cat. 300431), Brilliant Violet 605 anti-human TCR Cβ1 (BD ...
• Omicron BA.2 specifically evades broad sarbecovirus neutralizing antibodies

  Yunlong Cao, et al., bioRxiv - Immunology 2022

  Quote: ... FITC anti-human CD20 antibody (BioLegend, 302304), Brilliant Violet 421™ anti-human CD27 antibody (BioLegend ...
• Evolution of inflammation and immunity in a dengue virus 1 human infection model

  Adam T. Waickman, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-human IgA HRP (Biolegend, 411,002). Secondary antibody binding was quantified using the TMB Microwell Peroxidase Substrate System (KPL ...
• Evolution of inflammation and immunity in a dengue virus 1 human infection model

  Adam T. Waickman, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-human IgA HRP (Biolegend, 411,002). Secondary antibody binding was quantified using the TMB Microwell Peroxidase Substrate System (KPL ...
• Generation of PRKN and PINK1-KO and double KO cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 editing

  Carol X.-Q. Chen, et al., bioRxiv - Neuroscience 2022

  Quote: ... then blocked with Human TruStain FcX (Biolegend). Cells were stained with FACS antibodes (Table 2 ...
• Aging leads to DNA methylation alterations associated with loss of lineage fidelity and breast cancer in mammary luminal epithelial cells

  Parijat Senapati, et al., bioRxiv - Genomics 2022

  Quote: ... and anti-human CD271 (Biolegend, clone ME20.4) by following standard flow cytometry protocol ...
• MAP1LC3C regulates lysosomal exocytosis and induces zinc reprogramming in renal cancer cells

  Rita Verma, et al., bioRxiv - Cell Biology 2022

  Quote: ... pacific blue anti-human CD31 (303113, Biolegend) and anti-human CD45 (368539 ...
• Identification of HIV-Reservoir Cells with Reduced Susceptibility to Antibody-Dependent Immune Response

  Antonio Astorga-Gamaza, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-human HLA-DR (BV711, Biolegend) antibodies were used ...
• Multivalent, Bispecific αB7-H3-αCD3 Chemically Self-Assembled Nanorings Direct Potent T-cell Responses Against Medulloblastoma

  Ellie A. Mews, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-human CD8 (Biolegend, clone SK1, BV711), anti-human CD25 (Biolegend ...
• Human primed endothelial colony forming cells exert neuroprotective effects in the growth restricted newborn piglet

  Kirat K. Chand, et al., bioRxiv - Neuroscience 2021

  Quote: ... human CD45-FITC (BioLegend; dilution 1:25) and human CD31-V450 BD Biosciences ...
• Global Absence and Targeting of Protective Immune States in Severe COVID-19

  Alexis J. Combes, et al., bioRxiv - Immunology 2020

  Quote: ... and Human TruStain FcX block (BioLegend; #422302) were used to block pre-bound antibodies and Fc receptors ...
• CAR T cell entry into tumor islets is a two-step process dependent on IFNγ and ICAM-1

  Chahrazade Kantari-Mimoun, et al., bioRxiv - Immunology 2020

  Quote: ... AF647-anti-human CD3 (clone SK7, BioLegend), PE/Dazzle or BV421-anti-human EGFR (clone AY13 ...
• Structurally and functionally distinct early antibody responses predict COVID-19 disease trajectory and mRNA vaccine response

  Saborni Chakraborty, et al., bioRxiv - Immunology 2021

  Quote: ... and blocked with Human TruStain FcX (BioLegend) to reduce nonspecific binding ...
• Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

  Jeong Hyun Lee, et al., bioRxiv - Immunology 2021

  Quote: ... mouse anti-human CD20 BV785 (2H7, Biolegend), mouse anti-human PD1 BV605 (EH12.2H7 ...
• Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

  Jeong Hyun Lee, et al., bioRxiv - Immunology 2021

  Quote: ... mouse anti-human PD1 BV605 (EH12.2H7, Biolegend), mouse anti-human CXCR5 PE-Cy7 (MU5UBEE ...
• Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

  Jeong Hyun Lee, et al., bioRxiv - Immunology 2021

  Quote: ... mouse anti-human CD25 FITC (BC96, Biolegend), mouse anti-human CD16 APC-eFluor 780 (ebioCD16 ...
• Locally secreted BiTEs complement CAR T cells by enhancing solid tumor killing

  Yibo Yin, et al., bioRxiv - Cancer Biology 2021

  Quote: ... followed by human CD3 and CD8 (BioLegend) stain ...
• Human CD4⁺/CD8α⁺ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation

  Sothea Touch, et al., bioRxiv - Immunology 2022

  Quote: ... anti-human CCR6-PE (clone G034E3, Biolegend) and anti-human CXCR6-APC (clone K041E5 ...
• Cell type-programmable genome editing with enveloped delivery vehicles

  Jennifer R. Hamilton, et al., bioRxiv - Genomics 2022

  Quote: ... and anti-human CD19-PE (302208, Biolegend). Data analysis was performed using FlowJo v10 10.7.1 (FlowJo ...
• Differentiated neuroblastoma cells remain epigenetically poised for de-differentiation to an immature state

  Richard A. Guyer, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-human CD49b 1:750 (#359310 Biolegend), anti-mouse gp130 1:100 (#149404 Biolegend) ...
• An atlas of infiltrated B-lymphocytes in breast cancer revealed by paired single-cell RNA-sequencing and antigen receptor profiling

  Qingtao Hu, et al., bioRxiv - Immunology 2019

  Quote: ... FITC anti-human CD20 (BioLegend, Cat#302304) and FITC anti-human CD19 (BioLegend ...
• Natural killer cell activation by respiratory syncytial virus-specific antibodies is decreased in infants with severe respiratory infections and correlates with Fc-glycosylation

  Elisabeth A. van Erp, et al., bioRxiv - Immunology 2019

  Quote: ... anti-human CD56-PE (clone HCD56, Biolegend), and Fixable Viability Staining-eFluor780 (eBioscience) ...
• Aneuploidy and deregulated DNA damage response define haploinsufficiency in breast tissues of BRCA2 mutation carriers

  Mihriban Karaayvaz, et al., bioRxiv - Cancer Biology 2019

  Quote: ... BV650-conjugated anti-human EPCAM CD326 (Biolegend), biotin-conjugated anti-human ITGA6 (eBioscience) ...
• Dynamic regulation of CD45 by tetraspanin CD53

  V. E. Dunlock, et al., bioRxiv - Immunology 2019

  Quote: ... anti-human CD4-PerCP (RPA-T4, Biolegend), anti-human CD8-FITC (RPA-T8 ...
• Profiling microglia from AD donors and non-demented elderly in acute human post-mortem cortical tissue

  Astrid M. Alsema, et al., bioRxiv - Neuroscience 2020

  Quote: ... and PE anti-human CD11B (BioLegend, 301306). Single ...
• The von Willebrand Factor stamps Plasmatic Extracellular Vesicles from Glioblastoma Patients

  Quentin Sabbagh, et al., bioRxiv - Cancer Biology 2021

  Quote: ... PE anti-human CD63 staining (10896786, BioLegend) was next performed ...
• A T-cell independent universal cellular therapy strategy through antigen depletion

  Dan Li, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Human CD22 antibody were obtained from Biolegend. Apoptosis was measured using the Annexin V Apoptosis Detection Kit (BD Bioscience) ...