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251 - 300 of 8593 citations for 5 5 7 7 Tetramethyl 1 5 6 7 tetrahydrocyclopenta f indazol 4 amine since 2020

• Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor to promote neutrophilic inflammation

  Mieko Tokano, et al., bioRxiv - Immunology 2022

  Quote: CD4+ T cells (1 × 106) were stimulated for 7 days at 37°C with anti-mouse CD3 (BioLegend; 1 μg/mL) and CD28 (BioLegend ...
• NINJA: an inducible genetic model for creating neoantigens in vivo

  Martina Damo, et al., bioRxiv - Immunology 2020

  Quote: ... while P14 T cells were stained with antibodies specific for Thy1.1 (clone OX-7, BioLegend), CD8 (clone 53-6.7 ...
• A Novel CRISPR-Engineered, Stem Cell-Derived Cellular Vaccine

  Krishnendu Chakraborty, et al., bioRxiv - Immunology 2021

  Quote: ... cells were stained using a FITC Annexin V Apoptosis Detection Kit with 7-AAD (Biolegend). Proliferation of cells was measured staining of control and Irradiated UVC with either 2 μM Cell Trace Yellow (Abcam ...
• Antibody-mediated delivery of LIGHT to the tumor boosts Natural Killer cells and delays tumor progression

  Marco Stringhini, et al., bioRxiv - Immunology 2020

  Quote: ... as well as 7-AAD and Zombie Red viability dies were all purchased from BioLegend. AH1-loaded ...
• Membrane lectins enhance SARS-CoV-2 infection and influence the neutralizing activity of different classes of antibodies

  Florian A. Lempp, et al., bioRxiv - Microbiology 2021

  Quote: ... cells were pre-incubated with 10 ug/mL anti-SIGLEC1 antibody (Biolegend, clone 7-239) for 30 min ...
• Induction of a colitogenic phenotype in Th1 cells depends on IL-23R signaling

  Mathias Pawlak, et al., bioRxiv - Immunology 2021

  Quote: IEL and LPL were cultured overnight in complete medium with IL-7 (20ng/ml, Biolegend) + IL-23 (20ng/ml ...
• Tumor infiltrating iNKT cells sustain neutrophil pro-tumorigenic functions influencing disease progression in human colorectal cancer

  Georgia Lattanzi, et al., bioRxiv - Immunology 2022

  Quote: ... Cells were then stained with FITC Annexin V Apoptosis Detection Kit with 7-AAD (Biolegend) following manufacturer’s instruction and acquired at a FACS Celesta flow cytometer (BD Biosciences ...
• Spike-specific CXCR3⁺ T_FH cells play a dominant functional role in supporting antibody responses in SARS-CoV-2 infection and vaccination

  Jian Zhang, et al., bioRxiv - Immunology 2022

  Quote: ... mouse anti-human PE-Cy™7 CD27 (M-T271) (BioLegend, San Diego, CA, USA). Sorted TFH ...
• Porphyromonas gingivalis fuels colorectal cancer through CHI3L1-mediated iNKT cell-driven immune evasion

  Angélica Díaz-Basabe, et al., bioRxiv - Immunology 2023

  Quote: ... Cells were then stained with FITC Annexin V Apoptosis Detection Kit with 7-AAD (Biolegend) following manufacturer’s instruction and acquired at a FACS Celesta flow cytometer (BD Biosciences ...
• In vivo CRISPR screens identify GRA12 as a transcendent secreted virulence factor across Toxoplasma gondii strains and mouse subspecies

  Francesca Torelli, et al., bioRxiv - Microbiology 2024

  Quote: ... for 30 min before 7 h treatment with 20 ng/ml TNF-α (Biolegend 718004) and 100 nM SM-164 (Cayman 28632) ...
• Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritis

  Ping Wang, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL-4 and anti-IFN-γ (5 μg/mL, Biolegend) for 3 days.
• P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis

  Érika Machado de Salles, et al., bioRxiv - Immunology 2022

  Quote: ... 5 μg/ml of anti-IL-4 (11B11) mAb (Biolegend, USA), 5 ng/ml of IL-2 recombinant (eBioscience ...
• Eosinophils promote monocyte to macrophage differentiation and anti-bacterial immunity

  Gillian J Wilson, et al., bioRxiv - Immunology 2024

  Quote: ... BMDMs were stimulated on day 5 with either IL-4 (Biolegend) at 20 ng/ml ...
• The role of the atypical chemokine receptor CCRL2 in myelodysplastic syndrome and secondary acute myeloid leukemia

  Theodoros Karantanos, et al., bioRxiv - Cancer Biology 2021

  Quote: ... For the assessment of CD71 expression in TF-1 and DAMI cells were labeled with the phycoerythrin (PE)-cyanine 7 (Cy7)-conjugated CD71 (BioLegend) (#113811) ...
• Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset

  Gregory J. Golden, et al., bioRxiv - Immunology 2024

  Quote: ... cells were centrifuged at 500 xg for 7 minutes and resuspended in 1 mL ice cold Cell Stain Buffer (CSB, BioLegend). Samples were filtered through a sterile pre-wet 70 μm mesh ...
• Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform

  Santiago Naranjo, et al., bioRxiv - Cancer Biology 2021

  Quote: ... rabbit anti-Keratin 5 (1:5000, Biolegend, 905501), anti-TTF1 (1:500 ...
• Cells of the human intestinal tract mapped across space and time

  R Elmentaite, et al., bioRxiv - Cell Biology 2021

  Quote: ... FcγRI-PE (1:200, X54-5/7.1, BioLegend), FcγRIIB-PE (1:200 ...
• Fine-tuning of β-catenin in thymic epithelial cells is required for postnatal T cell development

  Sayumi Fujimori, et al., bioRxiv - Immunology 2021

  Quote: ... chicken anti-Keratin 5 antibody (BioLegend, 1:500), and mouse anti-Keratin 8 antibody (BioLegend ...
• Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) is Required for Immune Priming of the Endothelium in Atherogenic Disturbed Flow Conditions

  Jessica A Hensel, et al., bioRxiv - Cell Biology 2021

  Quote: ... CD4 (1:200, Biolegend 100536, clone RM4-5), CD45.2 (1:200 ...
• Dynamic states of cervical epithelia during pregnancy and epithelial barrier disruption

  Anne Cooley, et al., bioRxiv - Cell Biology 2022

  Quote: ... chicken anti-Keratin 5 (1:100, Biolegend 905901), and Biotinylated goat anti-rabbit IgG (1:200 ...
• Thymic epithelial organoids mediate T cell development

  Tania Hübscher, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Keratin 5 (BioLegend, Catalog No. 905501, 1/200), Keratin 8 (Abcam ...
• Thymic epithelial organoids mediate T cell development

  Tania Hübscher, et al., bioRxiv - Developmental Biology 2024

  Quote: ... Keratin 5 (BioLegend, Catalog No. 905501, 1/200), Keratin 8 (Abcam Catalog ...
• “Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models.”

  Irene Lara-Saez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-Keratin 5 (PRB-160P, BioLegend, 1:2000); anti-CC10 H-75 (sc-25554 ...
• HIGHLY PHAGOCYTIC LIPID-ASSOCIATED MACROPHAGES (LAMs) ARE INCREASED IN COLONIC LAMINA PROPRIA IN OBESITY

  Angela Castoldi, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (BV510, Biolegend, clone: RM4-5, 1:200), CD86 (BV650 ...
• A bivalent ChAd nasal vaccine protects against SARS-CoV-2 BQ.1.1 and XBB.1.5 infection and disease in mice and hamsters

  Baoling Ying, et al., bioRxiv - Microbiology 2023

  Quote: ... CD4-BV785 (1:100, clone: RM4-5, BioLegend), CD44-PE/Cyanine 7 (1:100 ...
• An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma

  Madelon M.E. de Jong, et al., bioRxiv - Immunology 2023

  Quote: ... CD11b(act)-PECy7 (1:100; CBRM1/5, BioLegend), CD11c-APCCy7 (1:100 ...
• HIGHLY PHAGOCYTIC LIPID-ASSOCIATED MACROPHAGES (LAMs) ARE INCREASED IN COLONIC LAMINA PROPRIA IN OBESITY

  Angela Castoldi, et al., bioRxiv - Immunology 2022

  Quote: ... CD64 (BV711, Biolegend, X54-5/7.1, 1:200), MHCII (PercpCy5.5 ...
• Integrated Organ Immunity: Antigen-specific CD4-T cell-derived IFN-γ induced by BCG imprints prolonged lung innate resistance against respiratory viruses

  Audrey Lee, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (1:200 dilution; clone RM4-5, BioLegend), CD44 (1:400 dilution ...
• An IL-1β driven neutrophil-stromal cell axis fosters a BAFF-rich microenvironment in multiple myeloma

  Madelon M.E. de Jong, et al., bioRxiv - Immunology 2023

  Quote: ... CD11b(act)-PECy7 (1:100; CBRM1/5, BioLegend), CD62L-PE Dazzle 594 (1:100 ...
• Regulators of health and lifespan extension in genetically diverse mice on dietary restriction

  Andrea Di Francesco, et al., bioRxiv - Genetics 2023

  Quote: ... Clone RM4-5 (Cat# 100542 Biolegend (1:40)) ...
• Requirement for Fc effector function is overcome by binding potency for broadly reactive anti-alphavirus antibodies

  Victoria Callahan, et al., bioRxiv - Microbiology 2024

  Quote: ... CD4 BV605 (clone RM4-5; BioLegend; 1:100), CD8 APC (clone 53.6.7 ...
• Resistance to vincristine in cancerous B-cells by disruption of p53-dependent mitotic surveillance

  Anne Bruun Rovsing, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and then washed and stained with PE-conjugated p53 antibody (Clone DO-7, BioLegend, Cat. 645805) 1:100 in 0.1% Triton X-100 0.5% BSA in PBS at room temperature for 30 min prior to a wash in 1% BSA in PBS ...
• Integrated single cell analysis shows chronic alcohol drinking disrupts monocyte differentiation in the bone marrow niche

  Sloan A. Lewis, et al., bioRxiv - Immunology 2023

  Quote: ... and CD169 (Biolegend, 7-239. Stained cells were then fixed and permeabilized using Fixation buffer (BioLegend) and incubated overnight with a cocktail of intracellular antibodies – IL-6 (BD Biosciences ...
• Seminal plasma inhibits Chlamydia trachomatis infection in vitro, and may have consequences on mucosal immunity

  Louis Reot, et al., bioRxiv - Immunology 2023

  Quote: ... 24h and 48h using an apoptosis detection kit with PE-Annexin V and 7-AAD (Biolegend), according to the manufacturer instructions ...
• Interferon induced circRNAs escape herpesvirus host shutoff and suppress lytic infection

  Sarah E Dremel, et al., bioRxiv - Microbiology 2023

  Quote: ... Cells were stained with Alexa Fluor 647 anti-mouse Thy-1.1 Antibody (BioLegend; clone OX-7) and enrichment was confirmed with CytoFlex S (Beckman Coulter) ...
• Spatio-temporal dynamics of the fibrotic niche in cardiac repair

  Andy Shing Fung Chan, et al., bioRxiv - Systems Biology 2024

  Quote: ... cells were washed with fresh medium with 0.1µg/mL recombinant human BMP-7 protein (Biolegend, 595601) or an equivalent amount of BSA ...
• The Cytomegalovirus M35 Protein Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes by Direct Promoter Binding

  Hella Schwanke, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Murine anti-V5-tag (clone 7/4, #680602) and rabbit anti-V5-tag (Polyclonal, #903801) antibodies were purchased from BioLegend (San Diego, CA, USA). Anti-V5-tag mAb-magnetic beads (#M167-11 ...
• Mapping the T cell repertoire to a complex gut bacterial community

  Kazuki Nagashima, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (RM4-5, BioLegend), CD3e (145-2C11 ...
• Disruption of Z-RNA–binding of ADAR1 induces Aicardi-Goutières syndrome–like encephalopathy in mice

  Taisuke Nakahama, et al., bioRxiv - Immunology 2020

  Quote: ... CD4 (RM4-5; BioLegend), CD8 (53-6.7 ...
• Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

  Dan Corral, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD8a (53-6.7 ...
• 12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes

  Abhishek Kulkarni, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD80 (16-10A1 ...
• Phosphoproteomic analysis of the AKT signalling axis in cutaneous squamous carcinoma progression reveals novel therapeutic targets

  R Button, C Harwood, RFL O’Shaughnessy, bioRxiv - Cancer Biology 2022

  Quote: ... Keratin 5 (BioLegend Poly19055) (1:1,000 WB) ...
• Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

  Carsten T. Charlesworth, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... CD4 (RM4-5; Biolegend), CD8 (54-6.7 ...
• IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

  Holly Bachus, et al., bioRxiv - Immunology 2022

  Quote: ... IL-5 (TRFK5; BioLegend), IL-4 (11B11 ...
• Atheroprone shear stress stimulates noxious endothelial extracellular vesicle uptake by MCAM and PECAM-1 cell adhesion molecules

  Pierre-Michaël Coly, et al., bioRxiv - Cell Biology 2023

  Quote: ... α5 integrin (Biolegend, 921704), α6 integrin (Biolegend ...
• CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

  Amélien Sanlaville, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD4 (RM4-5; Biolegend), NKp46 (29A1.4 ...
• Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

  Jiang Li, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD206 (C068C2 ...
• Interferon-γ Elicits Pathological Hallmarks of ALS in Human Motor Neurons

  Changho Chun, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD44 (C44Mab-5, BioLegend), and CD8 (SK1 ...
• A ketogenic diet reduces age-induced chronic neuroinflammation in mice

  Mitsunori Nomura, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, BioLegend), CD8 (53-6.7 ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD44 (IM7 ...