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201 - 250 of 2007 citations for 3 Bromo 4 8 dichloro 5 methoxyquinoline since 2020

• Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis

  Gabriela Pessenda, et al., bioRxiv - Immunology 2024

  Quote: ... TIM-4 (RMT4-54, Biolegend) 1:200 ...
• Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

  Jeong Hyun Lee, et al., bioRxiv - Immunology 2021

  Quote: ... TotalSeq-C anti-human Hashtag antibody 1-8 (LNH-94 and 2M2, Biolegend), TotalSeq-C0953 PE Streptavidin (Biolegend).
• Mapping the epitopes of the Human Leukocyte Antigen E antibodies 3D12 and 4D12

  Simon Brackenridge, et al., bioRxiv - Immunology 2023

  Quote: ... and 8 clones that were negative by surface staining with W6/32 (BioLegend) grown out ...
• Microbiome-derived metabolite effects on intestinal barrier integrity and immune cell response to infection

  Lauren Adams, et al., bioRxiv - Microbiology 2024

  Quote: ... 1L-8 and IL-15 were quantified using individual ELISA kits from (Biolegend), following the manufacturer’s protocol ...
• The dysregulated IL-23/T_H17 axis in endometriosis pathophysiology

  Danielle J. Sisnett, et al., bioRxiv - Immunology 2023

  Quote: ... injections of a TH17 priming cocktail (n=8; 0.5μg rmIL-6 [575704, BioLegend, USA] and 1μg rmTGF-β1 [763104 ...
• Multimodal identification of rare potent effector CD8 T cells in solid tumors

  Arja Ray, et al., bioRxiv - Immunology 2023

  Quote: ... Pooled 8:2 CD45+:CD45-cells were resuspended in Cell Staining Buffer (BioLegend) and stained with a pool of 137 TotalSeq-C antibodies (Table ...
• Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by metastasis

  Maha K. Rahim, et al., bioRxiv - Immunology 2022

  Quote: ... pooled 8:2 CD45+:CD45-cells were resuspended in Cell Staining Buffer (BioLegend) and stained with a pool of 137 TotalSeq-C antibodies (BioLegend ...
• Human placental organoids as a model to probe early gestation maternal immune dynamics

  Emily M. Slaby, et al., bioRxiv - Bioengineering 2024

  Quote: ... Chemokine Panel 1 (13-plex) w/VbP (Biolegend catalog #740985; CXCL8 (IL-8), CXCL10 (IP-10) ...
• CD300e as a Driver of Immunosuppressive Tumor Microenvironment in Colorectal Cancer

  Annica Barizza, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PerCP/Cyanine5.5 anti-mouse H-2Kb/H-2Db (clone 28-8-6; BioLegend), PE-Cyanine7 anti-mouse F4/80 (clone BM8 ...
• Mapping the T cell repertoire to a complex gut bacterial community

  Kazuki Nagashima, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (RM4-5, BioLegend), CD3e (145-2C11 ...
• Disruption of Z-RNA–binding of ADAR1 induces Aicardi-Goutières syndrome–like encephalopathy in mice

  Taisuke Nakahama, et al., bioRxiv - Immunology 2020

  Quote: ... CD4 (RM4-5; BioLegend), CD8 (53-6.7 ...
• Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

  Dan Corral, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD8a (53-6.7 ...
• 12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes

  Abhishek Kulkarni, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD80 (16-10A1 ...
• IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

  Holly Bachus, et al., bioRxiv - Immunology 2022

  Quote: ... IL-5 (TRFK5; BioLegend), IL-4 (11B11 ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD44 (IM7 ...
• Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

  Carsten T. Charlesworth, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... CD4 (RM4-5; Biolegend), CD8 (54-6.7 ...
• A ketogenic diet reduces age-induced chronic neuroinflammation in mice

  Mitsunori Nomura, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, BioLegend), CD8 (53-6.7 ...
• Phosphoproteomic analysis of the AKT signalling axis in cutaneous squamous carcinoma progression reveals novel therapeutic targets

  R Button, C Harwood, RFL O’Shaughnessy, bioRxiv - Cancer Biology 2022

  Quote: ... Keratin 5 (BioLegend Poly19055) (1:1,000 WB) ...
• Atheroprone shear stress stimulates noxious endothelial extracellular vesicle uptake by MCAM and PECAM-1 cell adhesion molecules

  Pierre-Michaël Coly, et al., bioRxiv - Cell Biology 2023

  Quote: ... α5 integrin (Biolegend, 921704), α6 integrin (Biolegend ...
• CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

  Amélien Sanlaville, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD4 (RM4-5; Biolegend), NKp46 (29A1.4 ...
• Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

  Jiang Li, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD206 (C068C2 ...
• Interferon-γ Elicits Pathological Hallmarks of ALS in Human Motor Neurons

  Changho Chun, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD44 (C44Mab-5, BioLegend), and CD8 (SK1 ...
• Interferon-sensitized hematopoietic progenitors dynamically alter organismal immunity

  Maria Guillamot, et al., bioRxiv - Immunology 2024

  Quote: ... CD4 (Biolegend RM4/5), CD8 (Biolegend ...
• LRRK2-dependent Rab GTPase phosphorylation in response to endolysosomal damage depends on macrophage differentiation

  Susanne Herbst, Maximiliano G. Gutierrez, bioRxiv - Cell Biology 2020

  Quote: ... anti-Galectin-3-AF647 (125408) from BioLegend and anti-CHMP4B (13683-1-AP ...
• The RAG1 Ubiquitin Ligase Domain Enhances the Assembly and Selection of T Cell Receptor Genes to Restrain the Autoimmune Hazard of Generating T Cell Receptor Diversity

  Thomas N. Burn, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml anti-CD28 (Biolegend) in RPMI with 10% FBS ...
• The antimicrobial peptide cathelicidin is critical for the development of Th17 responses in severe inflammatory disease

  Katie J Smith, et al., bioRxiv - Immunology 2022

  Quote: ... and rTGFβ (3 ng/ml; Biolegend, #580706), with or without 2.5μM mCRAMP ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... and rTGFβ (3 ng/ml; Biolegend, #580706), with or without 2.5 μM mCRAMP for 1 to 3 days ...
• Disruption of augmin-mediated microtubule nucleation in neural stem cells causes p53-dependent apoptosis and aborts brain development

  Ricardo Viais, et al., bioRxiv - Cell Biology 2020

  Quote: ... β3-tubulin (Biolegend #801201, dilution 1:1000), cleaved caspase-3 (Novus Biologicals #MAB835 ...
• Opposing roles of Granzymes A and B in the immune response to intestinal infection

  Maud Vandereyken, et al., bioRxiv - Immunology 2021

  Quote: ... [clone 1D4B (BioLegend)] and CD107b (Mac-3) [clone M384 (BioLegend)].
• Novel populations of Tr1 cells contribute to the resolution of acute influenza A virus infection

  Caitlin A Abbott, et al., bioRxiv - Immunology 2022

  Quote: ... and anti-mouse LAG-3 (C9B7W, Biolegend), which were stained for 60 min at 37°C as previously described (Gagliani et al. ...
• Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers

  Isaac Dean, et al., bioRxiv - Immunology 2023

  Quote: ... IgG2b BV605 or R718 (R12-3, BioLegend), IL-7Rα BV605 or BV421 (AFR34 ...
• Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations

  Aisha Souquette, et al., bioRxiv - Immunology 2023

  Quote: ... Panel 3) CD3-AF700 (Biolegend Cat. 300323), CD4-APC Fire750 (Biolegend Cat ...
• Modulating the proliferative and cytotoxic properties of human TIL by a synthetic immune niche of immobilized CCL21 and ICAM1

  Sharon Yunger, et al., bioRxiv - Immunology 2022

  Quote: ... FITC-TIM-3 (clone F38-2E2, BioLegend), FITC-LAG-3 (clone 11C3C65 ...
• The transcription factor IRF-5 is essential for the metabolic rewiring of CD8 T cells during chronic infection

  Linh Thuy Mai, et al., bioRxiv - Immunology 2024

  Quote: ... anti TIM-3-BV605 (RMT3-23, Biolegend), anti CD44-PE-Cy7 (IM7 ...
• Systematic functional screening of chromatin factors identifies strong lineage and disease dependencies in normal and malignant haematopoiesis

  D Lara-Astiaso, et al., bioRxiv - Genomics 2022

  Quote: ... CD55 (PE-conjugated; clone RIKO-3; Biolegend), CD41 (APC-conjugated ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Galectin-3 (1:1000; Biolegend, 125401), anti-γ-H2AX (1:200 ...
• Novel inhibitors of acute, axonal DLK palmitoylation are neuroprotective and avoid the deleterious side effects of cell-wide DLK inhibition

  Xiaotian Zhang, et al., bioRxiv - Neuroscience 2024

  Quote: ... β3 tubulin (mouse, BioLegend, TUJ1, #MMS-435P), myc (rabbit ...
• Macropinocytosis controls metabolic stress-driven CAF subtype identity in pancreatic cancer

  Yijuan Zhang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PE anti-mouse CD366 (Tim-3) (Biolegend), PE/Cy7 anti-mouse CD279 (PD-1 ...
• SOX2-induced IL1α-mediated immune suppression drives epithelial dysplasia malignant transformation

  Hülya F. Taner, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-Tim-3 (clone RMT3-23, BioLegend), anti-TCRγ/δ (clone GL3 ...
• Enhanced anti-tumor activity by Zinc Finger Repressor-driven epigenetic silencing of immune checkpoints and TGFBR2 in CAR-T cells and TILs

  Marion David, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LAG-3 and TGFBR2 (Biolegend, Amsterdam, Netherlands). For TILs characterization ...
• Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

  Alexander J. Nelson, et al., bioRxiv - Immunology 2024

  Quote: ... IL-4 neutralization was performed using anti-IL-4 (10 µg/mL, clone 11B11, BioLegend) or rat IgG1 isotype control (10 µg/mL ...
• Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

  Or-Yam Revach, et al., bioRxiv - Cancer Biology 2024

  Quote: ... T cells were activated for 3 days using 3 μg anti-human CD3 and CD28 antibodies (Biolegend, 300438, 377604) and 50 ng/mL of IL-2 (Peprotech ...
• Glycyrrhizin inhibits LPS-induced inflammatory responses in goat ruminal epithelial cells in vitro

  Xuanxuan Pu, et al., bioRxiv - Zoology 2020

  Quote: ... IL-8 and IL-12 were gotten from Biolegend (Camino Santa Fe, CA, USA). BCA protein quantitative kit and SYBR Green PCR kit were purchased from Smer Fell Science and Technology Co. ...
• CiDRE⁺ M2c macrophages hijacked by SARS-CoV-2 cause COVID-19 severity

  Yuichi Mitsui, et al., bioRxiv - Immunology 2022

  Quote: ... and MRP-8/14 in human blood serum were measured by ELISA kits (BioLegend, R&D Systems ...
• Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36

  Maria N Barrachina, et al., bioRxiv - Cell Biology 2023

  Quote: μ-side 8-well Ibidi chambers were coated with an anti-CD31 antibody (102502, BioLegend) for 30 min ...
• Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders

  Luca Pagliaroli, et al., bioRxiv - Genomics 2021

  Quote: ... 4 µl of the respective antibodies were used: APC anti-human SSEA-4 antibody (Biolegend, #330417) and PE anti-human TRA-1-60-R antibody (Biolegend ...
• Characterizing the polarization continuum of macrophage subtypes M1, M2a and M2c

  TCL Oates, et al., bioRxiv - Immunology 2022

  Quote: ... with or without the inclusion of interleukin-4 at 20ng/mL (wt/vol, IL-4, BioLegend), interferon-g at 2.5ng/mL (wt/vol ...
• The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin

  Martina Damo, et al., bioRxiv - Immunology 2021

  Quote: ... CTLA-4 (clone UC10-4B9, BioLegend), EpCAM (clone G8.8 ...
• Phosphatidylserine binding regulates TIM-3 effects on T cell receptor signaling

  Courtney M. Smith, et al., bioRxiv - Biochemistry 2021

  Quote: ... anti-TIM-4 (BioLegend, catalog #354003), anti-PD-L1 (also labeled with Dazzle 594 ...
• Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4⁺ regulatory T cells

  Mark Mensink, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CTLA-4-PE-Dazzle594 (BioLegend) and anti-NFATC2-AF488 (Cell Signaling Technology ...