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151 - 200 of 2155 citations for 2' 3' Dimethyl 3 2 5 dimethylphenyl propiophenone since 2020

• Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

  Rhianna Jones, et al., bioRxiv - Immunology 2021

  Quote: ... CD32 (FUN-2; BioLegend), CD95 (DX2 ...
• Regeneration of humoral immunity from pluripotent stem cells by defined transcription factors

  Qi Zhang, et al., bioRxiv - Immunology 2021

  Quote: ... CD138(281-2, BioLegend), CD38(90 ...
• Deep immune profiling of the maternal-fetal interface with mild SARS-CoV-2 infection

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Circulating mast cell progenitors migrate to atopic dermatitis-like skin then adapt locally

  Yuki Honda Keith, et al., bioRxiv - Immunology 2022

  Quote: ... integrinβ2 (M18/2; BioLegend), IgE (R35-72 ...
• Integration of Avidity and Differentiation is enabled by CD8⁺ T-cell sensing of IFN-γ

  Lion F.K. Uhl, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend, #575404), IL-1β (Biolegend ...
• Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

  Lucy Cooper, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 (Biolegend #155863) for 20 minutes at 4°C ...
• Novel Fas-TNFR chimeras that prevents Fas ligand-mediated kill and signals synergistically to enhance CAR T-cell efficacy

  Callum McKenzie, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... IL-2 (Biolegend; 431804), CCL1 (R&D Systems ...
• Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-T_SCM cells using qCART, the Quantum pBac-based CAR-T system

  Peter S. Chang, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and IL-2 (BioLegend) were quantified by ELISA according to manufacturer’s instructions.
• Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

  Yuhao Shi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD8b.2 (Biolegend, 140416), Granzyme B (Biolegend ...
• Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells

  Joshua B. Perkins, et al., bioRxiv - Immunology 2024

  Quote: ... CD8a (Ly-2, BioLegend), and CCR6 (29-2L17 ...
• Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation

  Hrishikesh S. Kulkarni, et al., bioRxiv - Immunology 2024

  Quote: ... CD138 (281-2; Biolegend) CD38 (S21016F ...
• Loss of the adhesion protein Kindlin-1 stimulates tumor clearance via modulation of Tregs

  Emily R Webb, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TGFß (1 ng/ml; cat#763102) and IL-2 (5 ng/ml, cat# 575402; All Biolegend) were added along with T cell media (RPMI ...
• Identification of functional immune and neuronal tumor cells in glioma

  Rachel Naomi Curry, et al., bioRxiv - Cancer Biology 2022

  Quote: ... spun at 700 g for 3 minutes at 4°C and washed in MACS Buffer 3× before being incubated with the following antibodies: APC-conjugated rat anti-CD3 (5 μL/10×106 cells; Biolegend, 100408), PE-conjugated rat anti-CD8b (2.5 μL/10×106 cells ...
• Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

  Yunlong Cao, et al., bioRxiv - Immunology 2022

  Quote: ... 2 μl PE/Cyanine7 anti-human IgD antibody (BioLegend, 348210, clone: IA6-2), 0.13 μg biotinylated SARS-CoV-2 BA.2 RBD protein (customized from Sino Biological ...
• Long-term efficacy of adoptive cell therapy is determined by host CD8⁺ T cells and undermined by lymphodepleting preconditioning

  Diego Figueroa, et al., bioRxiv - Immunology 2024

  Quote: ... 100 UI/mL of recombinant human IL-2 (rhIL-2; Biolegend, ref 589108) and 50 μM of 2-mercaptoethanol (Merck ...
• Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain

  Xiao Niu, et al., bioRxiv - Immunology 2024

  Quote: ... 2 μL PE/Cyanine7 anti-human IgD antibody (BioLegend, 348210, clone: IA6-2), 0.013 μg biotinylated SARS-CoV-2 BA.5/BF.7 NTD protein (Sino Biological ...
• Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritis

  Ping Wang, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD28 and anti-CD40 (3 μg/mL, Biolegend) in a round-bottom 96-well plate ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma

  Eugenia Zah, et al., bioRxiv - Bioengineering 2020

  Quote: ... LAG-3 (eBioscience #17-2239-42 or BioLegend #369314), CD8 (Miltenyi #130-113-164) ...
• SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8

  Valentina Salvi, et al., bioRxiv - Immunology 2021

  Quote: ... FITC-conjugated anti-mouse CD40 (clone HM40-3, Biolegend) and APC-CY7-conjugated anti-mouse CD86 (clone GL-1 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-Tubulin β 3 (Tuj1; Biolegend MMS-435P; 1:200). The appropriate secondary antibody (Alexa Fluor 594 goat anti-rabbit ...
• Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

  Ning Yang, et al., bioRxiv - Microbiology 2021

  Quote: ... and stained with antibodies against CD40 (3/23, Biolegend) and CD86 (GL-1 ...
• STING suppresses cancer pain via immune and neuronal modulation

  Kaiyuan Wang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... CD-3 APC/cy7 (1:200, rat, Biolegend, 100221), CD-4 APC (1:200 ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... with 3 μl of Annexin-V-APC (640941, BioLegend) and DAPI (200 ng/ml) ...
• Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease

  Adriaan van der Graaf, et al., bioRxiv - Genetics 2020

  Quote: ... or IL-21 (3 ng/ml, Biolegend, cat 571204) (n=8 samples per condition ...
• A microbiota-derived metabolite instructs peripheral efferocytosis

  Pedro H. V. Saavedra, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml recombinant annexin V (BioLegend, 640901) for 1 hour at 4 °C ...
• Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

  Aidan M. Tousley, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... TIM-3 (BV510 or BV650, Clone F38-2E2, BioLegend), LAG-3 (PE ...
• Prox2+ and Runx3+ neurons regulate esophageal motility

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Tubulin β-3 (BioLegend, Poly18020, 1:1000), goat anti-CTb (List Labs ...
• FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats

  Peter Aldiss, et al., bioRxiv - Physiology 2024

  Quote: ... anti-galectin-3 (cat. 125402, Biolegend, San Diego, CA), alpha-smooth muscle action (α-SMA ...
• Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1⁺ macrophages

  Jiangyan Yu, et al., bioRxiv - Immunology 2023

  Quote: ... Then cells were stained with CCR7 (3:100, BioLegend) and CADM1 (2:100 ...
• PP2A catalytic subunit alpha is critically required for CD8⁺ T cell homeostasis and anti-bacterial responses

  Xian Zhou, et al., bioRxiv - Immunology 2024

  Quote: ... Alexa fluor 700-labeled anti-CD8β (Lyt-3; Biolegend), BV650-labeled anti-CD45.1 (Ly5.1 ...
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Targeting GFPT2 to reinvigorate immunotherapy in EGFR-mutated NSCLC

  Luyao Ao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Panel 3: BV421-conjugated CD45 (1:100, 103133, Biolegend), PE/Cy7 conjugated F4/80 (1:100 ...
• MiR-324-5p regulates the structure of dendritic spines and is essential for hippocampal long-term potentiation

  Emma V Parkins, et al., bioRxiv - Neuroscience 2023

  Quote: ... Beta 3 tubulin rabbit polyclonal (BioLegend Cat# 802001, RRID:AB_2564645), Anti-PSD-95 MAGUK scaffold protein mouse monoclonal (Antibodies Incorporated Cat# 75-348 ...
• Broad-spectrum RNA antiviral inspired by ISG15^-/- deficiency

  Yemsratch T. Akalu, et al., bioRxiv - Immunology 2024

  Quote: ... or with anti-cleaved caspase-3 antibody (Biolegend 559341) for quantification by flow cytometry.
• Human effector CD8⁺ T cells with an exhausted-like phenotype control tumor growth in vivo in a humanized tumor model

  Juliane Mietz, et al., bioRxiv - Immunology 2024

  Quote: ... Galectin-9-PE-Cy7 (Biolegend, 9M1-3, Cat. 348916), TIGIT-APC-Cy7 (Biolegend ...
• LAG-3 blockade reactivates the CD8⁺ T cell expansion program to re-expand contracted clones in the tumor

  Munetomo Takahashi, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-LAG-3 (clone C9B7W, BioLegend or Selleck) was injected intraperitoneally at a dose of 200 μg per mouse on days 14 and 16 (for bulk RNA-seq data ...
• Cancer-associated adipocytes mediate CD8⁺T cell dysfunction via FGF21-driven lipolysis

  Sumiya Dalangood, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-TIM-3-PE/Cy7 (cat#134009, CloneB8.2C12, Biolegend), anti-LAG3-Percp/Cyanine5.5 (cat#125211 ...
• Catabolism of extracellular glutathione supplies amino acids to support tumor growth

  Fabio Hecht, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 3 µL of Annexin V-FITC (Biolegend 0640906). Then ...
• Binary outcomes of enhancer activity underlie stable random monoallelic expression

  Djem U. Kissiov, et al., bioRxiv - Molecular Biology 2021

  Quote: ... or day 5 IL-2 cultured NK cells isolated using the MojoSort NK isolation kit from Biolegend, but instead of analysis by flow cytometry ...
• Immunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and function

  Paul Renauer, et al., bioRxiv - Cancer Biology 2023

  Quote: ... supplemented with 5 % human AB serum (Gemini Bio) and 30 U / mL recombinant human IL-2 (BioLegend) [9] ...
• Immunogenetic metabolomics revealed key enzymes that modulate CAR-T metabolism and function

  Paul Renauer, et al., bioRxiv - Cancer Biology 2023

  Quote: ... supplemented with 5 % human AB serum (Gemini Bio) and 30 U / mL recombinant human IL-2 (BioLegend). The viability of NALM6-GL cells was then assessed by adding 150 ug / mL D-Luciferin (PerkinElmer ...
• Sodium chloride in the tumor microenvironment enhances T-cell metabolic fitness and cytotoxicity

  Dominik Soll, et al., bioRxiv - Immunology 2023

  Quote: ... rhIL-2 (50 Uml-1, Novartis) and anti-mIFN-γ (5 µg ml-1, clone XMG1.2, Biolegend) in the presence or absence of 30 mM NaCl ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... plates were coated at least 5 hours prior to use with 3 ug/ml plate-bound anti-CD3 antibody (clone OKT3; BioLegend, LEAF grade), 1 ug/ml soluble anti-CD28 antibody (BioLegend ...
• Macrophages in the uterus are functionally specialised and continually replenished from the circulation

  Nicholas A. Scott, et al., bioRxiv - Immunology 2021

  Quote: ... in PBS with 2% FCS and 2% EDTA (FACS buffer) with Fc block (Biolegend) for 25 minutes ...
• Cytotoxic CD4⁺ T cells eliminate senescent cells by targeting cytomegalovirus antigen

  Tatsuya Hasegawa, et al., bioRxiv - Immunology 2023

  Quote: ... and 2 ng/ml human interleukin (IL)-2 recombinant (BioLegend, San Diego, CA, 589104).
• Innate receptors with high specificity for HLA class I–peptide complexes

  Malcolm J. W. Sim, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 concentration in thawed supernatant was measured by ELISA (Biolegend, IL-2 human). For experiments with KIR2DS1 reporter cells ...
• Integrated, high-dimensional analysis of CD4 T cell epitope specificities and phenotypes reveals unexpected diversity in the response to Mycobacterium tuberculosis

  Heather L Mead, et al., bioRxiv - Immunology 2024

  Quote: ... Media included recombinant human interleukin-2 (IL-2) at 230IU/mL – 1,025IU/mL (Biolegend), with the lower concentrations used on days 1-2 ...
• Endothelial mTOR maintains hematopoiesis during aging

  Pradeep Ramalingam, et al., bioRxiv - Cell Biology 2020

  Quote: ... Diamidino-2-Phenylindole (DAPI) (Biolegend) for live/dead exclusion and cell sorting ...
• Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IL-2 (MQ1-17H12, Biolegend), and IFNγ (4S.B3 ...