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101 - 150 of 1916 citations for 3' Chloro 3 3 chloro 5 fluorophenyl 4' fluoropropiophenone since 2020

• Protamine 2 Deficiency Results In Septin 12 Abnormalities

  Ondrej Sanovec, et al., bioRxiv - Cell Biology 2024

  Quote: ... samples were permeabilized with the Intracellular Staining Perm Wash Buffer for 3 x 5 min (421002, BioLegend), followed by blocking in Superblock solution (Invitrogen ...
• Large-scale statistical mapping of T-cell receptor β sequences to Human Leukocyte Antigens

  H. Jabran Zahid, et al., bioRxiv - Immunology 2024

  Quote: 3−5×107 PBMC were stained using a cocktail of antibodies that included CD3 (clone UCHT1, Biolegend), CD4 (clone OKT4 ...
• Natural killer-like B cells promote Th17 cell differentiation and exacerbate rheumatoid arthritis

  Ping Wang, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD28 and anti-CD40 (3 μg/mL, Biolegend) in a round-bottom 96-well plate ...
• High Frequencies of PD-1⁺TIM3⁺TIGIT⁺CTLA4⁺ Functionally Exhausted SARS-CoV-2-Specific CD4⁺ and CD8⁺ T Cells Associated with Severe Disease in Critically ill COVID-19 Patients

  Pierre-Gregoire Coulon, et al., bioRxiv - Immunology 2022

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma

  Eugenia Zah, et al., bioRxiv - Bioengineering 2020

  Quote: ... LAG-3 (eBioscience #17-2239-42 or BioLegend #369314), CD8 (Miltenyi #130-113-164) ...
• SARS-CoV-2-associated ssRNAs activate inflammation and immunity via TLR7/8

  Valentina Salvi, et al., bioRxiv - Immunology 2021

  Quote: ... FITC-conjugated anti-mouse CD40 (clone HM40-3, Biolegend) and APC-CY7-conjugated anti-mouse CD86 (clone GL-1 ...
• Retroviral Infection of Human Neurospheres and Use of Stem Cell EVs to Repair Cellular Damage

  Heather Branscome, et al., bioRxiv - Cell Biology 2021

  Quote: ... α-Tubulin β 3 (Tuj1; Biolegend MMS-435P; 1:200). The appropriate secondary antibody (Alexa Fluor 594 goat anti-rabbit ...
• Vaccinia E5 is a major inhibitor of the DNA sensor cGAS

  Ning Yang, et al., bioRxiv - Microbiology 2021

  Quote: ... and stained with antibodies against CD40 (3/23, Biolegend) and CD86 (GL-1 ...
• STING suppresses cancer pain via immune and neuronal modulation

  Kaiyuan Wang, et al., bioRxiv - Cancer Biology 2021

  Quote: ... CD-3 APC/cy7 (1:200, rat, Biolegend, 100221), CD-4 APC (1:200 ...
• Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in lung adenocarcinoma

  Chun-Chun Cheng, et al., bioRxiv - Cancer Biology 2020

  Quote: ... with 3 μl of Annexin-V-APC (640941, BioLegend) and DAPI (200 ng/ml) ...
• Circulating levels of epirubicin cause endothelial senescence while compromising metabolic activity and vascular function

  Amanda J Eakin, et al., bioRxiv - Cell Biology 2020

  Quote: ... rat anti-mouse Mac-2 (Galectin-3, 125402, Biolegend) for myeloid cells (Ho and Springer 1982) ...
• Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease

  Adriaan van der Graaf, et al., bioRxiv - Genetics 2020

  Quote: ... or IL-21 (3 ng/ml, Biolegend, cat 571204) (n=8 samples per condition ...
• MiR-324-5p regulates the structure of dendritic spines and is essential for hippocampal long-term potentiation

  Emma V Parkins, et al., bioRxiv - Neuroscience 2023

  Quote: ... Beta 3 tubulin rabbit polyclonal (BioLegend Cat# 802001, RRID:AB_2564645), Anti-PSD-95 MAGUK scaffold protein mouse monoclonal (Antibodies Incorporated Cat# 75-348 ...
• Targeting GFPT2 to reinvigorate immunotherapy in EGFR-mutated NSCLC

  Luyao Ao, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Panel 3: BV421-conjugated CD45 (1:100, 103133, Biolegend), PE/Cy7 conjugated F4/80 (1:100 ...
• FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats

  Peter Aldiss, et al., bioRxiv - Physiology 2024

  Quote: ... anti-galectin-3 (cat. 125402, Biolegend, San Diego, CA), alpha-smooth muscle action (α-SMA ...
• PP2A catalytic subunit alpha is critically required for CD8⁺ T cell homeostasis and anti-bacterial responses

  Xian Zhou, et al., bioRxiv - Immunology 2024

  Quote: ... Alexa fluor 700-labeled anti-CD8β (Lyt-3; Biolegend), BV650-labeled anti-CD45.1 (Ly5.1 ...
• A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

  Swayam Prakash, et al., bioRxiv - Immunology 2024

  Quote: ... anti-TIM-3 (BV 711, clone F38-2E2 – BioLegend), anti-PD1 (PE-Cy7 ...
• Early-stage idiopathic pulmonary fibrosis is characterized by bronchoalveolar accumulation of SPP1⁺ macrophages

  Jiangyan Yu, et al., bioRxiv - Immunology 2023

  Quote: ... Then cells were stained with CCR7 (3:100, BioLegend) and CADM1 (2:100 ...
• A microbiota-derived metabolite instructs peripheral efferocytosis

  Pedro H. V. Saavedra, et al., bioRxiv - Immunology 2022

  Quote: ... and 3 μg/ml recombinant annexin V (BioLegend, 640901) for 1 hour at 4 °C ...
• Type 1 interferon remodels normal and neoplastic hematopoiesis in human

  Chhiring Lama, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 2 or 3 (TotalSeq-A, clone LNH-94, Biolegend) for GoT-IM ...
• Coopting T cell proximal signaling molecules enables Boolean logic-gated CAR T cell control

  Aidan M. Tousley, et al., bioRxiv - Synthetic Biology 2022

  Quote: ... TIM-3 (BV510 or BV650, Clone F38-2E2, BioLegend), LAG-3 (PE ...
• Prox2+ and Runx3+ neurons regulate esophageal motility

  Elijah D. Lowenstein, et al., bioRxiv - Neuroscience 2022

  Quote: ... rabbit anti-Tubulin β-3 (BioLegend, Poly18020, 1:1000), goat anti-CTb (List Labs ...
• Human effector CD8⁺ T cells with an exhausted-like phenotype control tumor growth in vivo in a humanized tumor model

  Juliane Mietz, et al., bioRxiv - Immunology 2024

  Quote: ... Galectin-9-PE-Cy7 (Biolegend, 9M1-3, Cat. 348916), TIGIT-APC-Cy7 (Biolegend ...
• LAG-3 blockade reactivates the CD8⁺ T cell expansion program to re-expand contracted clones in the tumor

  Munetomo Takahashi, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-LAG-3 (clone C9B7W, BioLegend or Selleck) was injected intraperitoneally at a dose of 200 μg per mouse on days 14 and 16 (for bulk RNA-seq data ...
• Broad-spectrum RNA antiviral inspired by ISG15^-/- deficiency

  Yemsratch T. Akalu, et al., bioRxiv - Immunology 2024

  Quote: ... or with anti-cleaved caspase-3 antibody (Biolegend 559341) for quantification by flow cytometry.
• Cancer-associated adipocytes mediate CD8⁺T cell dysfunction via FGF21-driven lipolysis

  Sumiya Dalangood, et al., bioRxiv - Cancer Biology 2024

  Quote: ... anti-TIM-3-PE/Cy7 (cat#134009, CloneB8.2C12, Biolegend), anti-LAG3-Percp/Cyanine5.5 (cat#125211 ...
• Catabolism of extracellular glutathione supplies amino acids to support tumor growth

  Fabio Hecht, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and 3 µL of Annexin V-FITC (Biolegend 0640906). Then ...
• TLR7/8 stress response drives histiocytosis in SLC29A3 disorders

  Takuma Shibata, et al., bioRxiv - Immunology 2022

  Quote: ... 3-4 × 106 splenocytes after cell surface staining were fixed with Cyto-Fast Fix/Perm buffer (BioLegend, USA) for 20 min at room temperature and washed twice with FACS staining buffer ...
• BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infection

  Yunlong Cao, et al., bioRxiv - Immunology 2022

  Quote: ... 3 μL PE/Cyanine7 anti-human IgM antibody (BioLegend, 314532), 0.0052 μg biotinylated Ovalbumin (SinoBiological ...
• CAR-NK Cells Effectively Target the D614 and G614 SARS-CoV-2-infected Cells

  Minh Ma, et al., bioRxiv - Immunology 2021

  Quote: ... FITC anti-human CD223 (LAG-3) antibody (clone 11C3C65, BioLegend), BV510 anti-human CD314 (NKG2D ...
• FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

  Célia Jeronimo, et al., bioRxiv - Molecular Biology 2020

  Quote: ... anti-Rpb3 (Neoclone W0012, 3 μL; BioLegend 665004, 1.5 μL), anti-Flag (Sigma-Aldrich F3165 ...
• Type I Interferon Transcriptional Network Regulates Expression of Coinhibitory Receptors in Human T cells

  Tomokazu S. Sumida, et al., bioRxiv - Immunology 2020

  Quote: ... The following antibodies were used: anti-LAG-3 (11C3C65, BioLegend), anti-PD-1 (EH12.1 ...
• Efficacy of Targeting SARS-CoV-2 by CAR-NK Cells

  Minh Ma, Saiaditya Badeti, Ke Geng, Dongfang Liu, bioRxiv - Immunology 2020

  Quote: ... FITC anti-human CD223 (LAG-3) antibody (clone 11C3C65, BioLegend), BV510 anti-human CD314 (NKG2D ...
• Profound Treg perturbations correlate with COVID-19 severity

  Silvia Galván-Peña, et al., bioRxiv - Immunology 2020

  Quote: ... CD127 AF488 (clone A019D5, BioLegend, cat# 351314, dilution 3:100); CD25 PE-Cy7 (clone BC96 ...
• CD8+ T cell epitope variations suggest a potential antigen presentation deficiency for spike protein of SARS-CoV-2

  Congling Qiu, et al., bioRxiv - Immunology 2021

  Quote: ... washed for 3 times with Washing Buffer (BioLegend Cat#421601) and blocked with Dilution Buffer (0.5M Tris pH 8.0 ...
• Cell-Intrinsic and Extrinsic Effects of Galectin-1 and Galectin-3 in B-Cell Precursor Acute Lymphoblastic Leukemia

  Fei Fei, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cells were incubated with PE-Galectin-3 (Biolegend cat# 126706) or matched isotype control for 15 mins and analyzed on BD Accuri C6 cytometer (BD Biosciences ...
• Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas

  Julie Stockis, et al., bioRxiv - Immunology 2024

  Quote: ... injection of 3 µg anti-CD45.2-PE (clone 104, Biolegend) antibody 3 min prior to sacrifice ...
• Activity-dependent development of the body’s touch receptors

  Celine Santiago, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Tubulin beta 3 (TUBB3) (Biolegend #Poly18020, 1:500), rabbit anti-S100 Beta (VWR/Protein Tech #15146-1-AP ...
• Early infection response of the first trimester human placenta at single-cell scale

  Regina Hoo, et al., bioRxiv - Genomics 2023

  Quote: ... TotalSeq™-B0253 anti-human Hashtag 3 Antibody (394635, Biolegend), TotalSeq™-B0254 anti-human Hashtag 4 Antibody (394637 ...
• Interleukin-1 receptor antagonist is a conserved driver of tuberculosis

  Dmitri I. Kotov, et al., bioRxiv - Immunology 2024

  Quote: ... and anti-mouse TotalSeq-A Hashtag antibody (1-3; BioLegend). The stained T cell samples were then incubated with Sytox Green Dead Cell Stain (Thermo Fisher Scientific ...
• Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s Disease

  Rikesh M. Rajani, et al., bioRxiv - Neuroscience 2024

  Quote: ... anti-Tubulin beta 3 (clone TUJ1; 1:1,000; BioLegend; 801202), IBA1 (1:500 ...
• Targeting CXCR4 with [²¹²Pb/²⁰³Pb]-Pentixather Significantly Increases Overall Survival in Small Cell Lung Cancer

  Keegan A. Christensen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 3×106 cells were stained with Zombie Aqua (423102, BioLegend) for 20 min at room temperature for live/dead cells discrimination ...
• Stratified analysis identifies HIF-2α as a therapeutic target for highly immune-infiltrated melanomas

  Amy Y. Huang, et al., bioRxiv - Cancer Biology 2024

  Quote: ... TIM-3 BV711 (clone RMT3-23, Biolegend 119727, 1:200), Foxp3 FITC (clone FJK-16s ...
• Aging trajectories of memory CD8⁺ T cells differ by their antigen specificity

  Ines Sturmlechner, et al., bioRxiv - Immunology 2024

  Quote: ... about 3-4 million CD8+ T cells were blocked with Fc receptor blocking solution (Human TruStain FcX, BioLegend, #422302) for 10 minutes on ice and stained with BEAM-T assemblies for 15 minutes on ice ...
• Naïve and in vitro-activated primary mouse CD8⁺ T cells retain in vivo immune responsiveness after electroporation-based CRISPR/Cas9 genetic engineering

  Petra Pfenninger, Laura Yerly, Jun Abe, bioRxiv - Immunology 2021

  Quote: ... and seeded in the antibody-coated flask at 3–5×105 cells/cm2 together with soluble 1 µg/mL anti-CD28 antibodies (clone 37.51; 102116, BioLegend). Cells were cultured for 48 hr at 37°C in a humidified 5% CO2 atmosphere ...
• Roles of C/EBPα, GATA2, TGF-β-signaling, and epigenetic regulation in the expression of basophil-specific protease genes

  Ryotaro Tojima, et al., bioRxiv - Immunology 2024

  Quote: ... which is RPMI-1640-based and supplemented with 5 μg/mL recombinant mouse IL-3 (#575506 or #575508, BioLegend) as described in previous studies (6 ...
• Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

  Sofia Lövestam, et al., bioRxiv - Neuroscience 2024

  Quote: ... the cells were fixed with cold methanol for 3 min at room temperature and incubated overnight at 4 °C with an anti-HA antibody (diluted 1:2000) (Biolegend,). Cells were then rinsed three times with PBS and incubated for 1 h at room temperature with an Alexa647-conjugated goat anti-mouse antibody (diluted 1:1000 ...
• B cell receptor silencing reveals the origin of high-grade B cell lymphomas with MYC and BCL2 rearrangements

  Paola Sindaco, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Residual red blood cells (RBC) were lysed incubating cell suspension for 3 minutes at 4°C with 1X RBC Lysis Buffer (BioLegend). Cell suspensions were washed with PBS ...
• Prostacyclin as a Negative Regulator of Angiogenesis in the Neurovasculature

  Tasha R Womack, et al., bioRxiv - Neuroscience 2021

  Quote: ... Rat antibody against Notch 3 intracellular domain was obtained from Biolegend. Blots were probed with a mouse anti-actin (ThermoFisher ...
• Intracellular sterol sensing controls intestinal B cell differentiation

  Bruno C. Trindade, et al., bioRxiv - Immunology 2021

  Quote: ... Color development was stopped with 3 M H2SO4 stop solution (Biolegend). Purified mouse IgA (Southern Biotech ...