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51 - 100 of 8334 citations for 2 Bromo 1 5 bromofuran 2 yl ethanone since 2020

• CD38 regulates ovarian function and fecundity via NAD⁺ metabolism

  Rosalba Perrone, et al., bioRxiv - Developmental Biology 2023

  Quote: ... CD138-BV785 (BioLegend, clone 281-2, 142534, 1:800), CD38-Pac Blue (BioLegend ...
• Computationally designed mRNA-launched protein nanoparticle vaccines

  Grace G. Hendricks, et al., bioRxiv - Immunology 2024

  Quote: ... anti-IL-2 (PE; BioLegend #503808, 1:100 dilution), and anti-IL-4 (PerCPCy5.5 ...
• Regulatory T cell expansion by a highly CD25-dependent IL-2 mutein arrests ongoing autoimmunity

  Liliane Khoryati, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 immune complex (IL-2ic; mouse recombinant IL-2 + anti-IL-2 (JES6-1A12, BioLegend); molar ratio 2:1 ...
• LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade

  Izumi Yanatori, et al., bioRxiv - Cell Biology 2020

  Quote: ... mouse anti-Myc (1:2, 9E10 Hybridoma culture supernatant, 1:1000 Biolegend); rabbit anti pRab10 (1:1000 ...
• Tissue-bound hyaluronan molecular weight as a regulator of dendritic cell immune potency

  Brian Chesney Quartey, et al., bioRxiv - Bioengineering 2023

  Quote: THP-1 cells were incubated with 2 µg/ml of anti-CD44 antibodies (clone: C44Mab-5; Biolegend, San Diego, CA, USA) for 20 minutes under standard cell culture conditions (95% humidity and 5% CO2 at 37°C ...
• Grape extract and resveratrol mitigate sleep fragmentation, Aβ accumulation, and abnormal neuronal excitability in a Drosophila model of Alzheimer’s disease

  Ziqi Yu, Yangkun Xu, Yong Ping, bioRxiv - Neuroscience 2024

  Quote: ... We then blocked the brains in 5 % goat serum for 2 h and stained with mouse anti-Aβ42 (6E10) (1:500, BioLegend, CA, USA) in PBST on a shaker at 4 °C overnight ...
• Subset-specific and temporal control of effector and memory CD4+ T cell survival

  Sharmila Shanmuganad, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend), CD127 ...
• Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment

  Jacob Gadwa, et al., bioRxiv - Immunology 2024

  Quote: ... Bcl-2 (BioLegend) or Ki67 (BD Bioscience ...
• In vivo screening of tumor-hepatocyte interactions identifies Plexin B2 as a gatekeeper of liver metastasis

  Costanza Borrelli, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Hepatocytes were resuspended in 2 mL FACS buffer (2 mM EDTA, 0.5% BSA in PBS) and stained with Zombie Violet (1:500) (Biolegend #423113), TruStain FcX™ (anti-mouse CD16/32 ...
• Repeated LPS induces training and tolerance of microglial responses across brain regions

  Jennifer Kim, et al., bioRxiv - Neuroscience 2024

  Quote: ... sections were washed 3 times for 5 minutes each with 1xPBS + 0.03% Triton before incubating for 2 hours in secondary solution containing 2% NDS + DAPI (1:1000; Biolegend 422801) + secondary antibodies (Alexafluor 647 donkey anti-rabbit ...
• The human brain vasculature shows a distinct expression pattern of SARS-CoV-2 entry factors

  Moheb Ghobrial, et al., bioRxiv - Neuroscience 2020

  Quote: ... 6-diamidino-2-phenylindole (DAPI) (diluted 1:20’000; BioLegend, #422801). Finally ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IFNγ antibody (2 ug/ml; clone MD-1, Biolegend), anti-IL-4 antibody (2 ug/ml ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IFNγ antibody (2 ug/ml; clone MD-1, Biolegend), bexarotene (1 μM ...
• Molecular atlas of the human brain vasculature at the single-cell level

  Thomas Wälchli, et al., bioRxiv - Neuroscience 2021

  Quote: ... 6- diamidino-2-phenylindole (DAPI) (diluted 1:20,000; BioLegend, #422801). Finally ...
• Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity

  Robin C. Orozco, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (PE/BV421, Biolegend, 1:50, clone JES6-5H4), PDCA-1 (Pacific Blue ...
• A multi-enhancer hub at the Ets1 locus controls T cell differentiation and allergic inflammation through 3D genome topology

  Aditi Chandra, et al., bioRxiv - Genomics 2022

  Quote: ... 1 ng/mL of recombinant IL-2 (BioLegend, Cat#575402) and 1 μg /mL of soluble anti-CD28 (Clone ...
• The role of B cells in immune cell activation in polycystic ovary syndrome

  Angelo Ascani, et al., bioRxiv - Immunology 2023

  Quote: ... anti-mouse IgG1 (Biolegend; RMG1-1; at 2 μg/ml), antimouse IgG2b (BD Biosciences ...
• Origins and diversity of pan-isotype human bone marrow plasma cells

  Gaspar A. Pacheco, et al., bioRxiv - Immunology 2024

  Quote: ... anti-IgD-PerCP-Cy5.5 (clone IA6-2, BioLegend, 1:50), anti-CD3-FITC (clone HIT3a ...
• T cells expressing multiple co-inhibitory molecules in acute malaria are not exhausted but exert a suppressive function

  Johannes Brandi, et al., bioRxiv - Immunology 2021

  Quote: ... 2×106 cells were incubated for 5 hours with Brefeldin A (BioLegend, San Diego, California) and Monensin (BioLegend ...
• Immune dynamics at single cell protein level after delta/omicron infection in COVID-19 vaccinated convalescent individuals

  Rimpi Bajaj, et al., bioRxiv - Immunology 2022

  Quote: A 5-plex SARS-CoV-2 Variants Neutralizing Antibody Panel (BioLegend LEGENDplex, Cat. No. #741174) was used to measure the neutralization antibody concentration ...
• Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution

  Yunlong Cao, et al., bioRxiv - Immunology 2022

  Quote: ... Omicron RBD (BA.2 or BA.5) were labeled with TotalSeq-C0971 Streptavidin (Biolegend, 405271) and TotalSeq-C0972 Streptavidin (Biolegend ...
• Senescence rewires microenvironment sensing to facilitate anti-tumor immunity

  Hsuan-An Chen, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and cultured in presence of IL-2 (2 ng/ml; Biolegend), IL-7 (2.5 ng/ml ...
• Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8⁺ T cells to suppress anti-tumor immunity

  Joanne D. Tejero, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 ng/mL recombinant mouse interleukin-2 (IL-2) (BioLegend); additionally ...
• Structural surfaceomics reveals an AML-specific conformation of Integrin-β2 as a CAR-T therapy target

  Kamal Mandal, et al., bioRxiv - Cancer Biology 2022

  Quote: ... FACS buffer recipe was D-PBS + 5% FBS + 2% BSA + 5 mM EDTA + 50 µg/ml DNase-I with Human Trustain (Biolegend, 422302). All the compensation was done using UltraComp eBeads™ Compensation Beads (Invitrogen ...
• Development of a high-throughput pipeline to characterize microglia morphological states at a single-cell resolution

  Jennifer Kim, Paul Pavlidis, Annie Vogel Ciernia, bioRxiv - Neuroscience 2023

  Quote: ... sections were washed 3 times for 5 minutes each with 1xPBS + .03% Triton before incubating for 2 hours in secondary solution containing 2% NDS + DAPI (1:1000; Biolegend 422801) + secondary antibodies (Alexafluor 647 donkey anti-chicken ...
• Heterotypic responses against nsp12/nsp13 from prior SARS-CoV-2 infection associates with lower subsequent endemic coronavirus incidence

  David J. Bean, et al., bioRxiv - Immunology 2023

  Quote: ... buffer (PBS containing 2% FBS and 2 mM EDTA) and then incubated with human Fc receptor block (1:100 dilution, BioLegend, 422302) for 15 minutes on ice ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL-4 antibody (2 ug/ml; clone MD-1, Biolegend), bexarotene (1 μM ...
• Epstein-Barr virus promotes T cell dysregulation in a humanized mouse model of multiple sclerosis

  Jessica R. Allanach, et al., bioRxiv - Immunology 2023

  Quote: ... and 1 U/mL of recombinant human IL-2 (BioLegend, #589102) in 200 μL of complete culture medium (see above for media components) ...
• Antibody-mediated prevention of vaginal HIV transmission is dictated by IgG subclass in humanized mice

  Jacqueline M. Brady, et al., bioRxiv - Immunology 2022

  Quote: ... 1:50 diluted anti-human CD32-APC (BioLegend, clone FUN-2), and 1:50 diluted anti-human CD64-PE/DAZZLE594 (BioLegend ...
• Ezh2 knockout in B cells impairs plasmablast differentiation and ameliorates lupus-like disease in MRL/lpr mice

  Xiaoqing Zheng, et al., bioRxiv - Immunology 2022

  Quote: ... PE/Cyanine7 anti-mouse CD138 (Syndecan-1) (Clone 281-2, BioLegend), and the same anti-CD19 ...
• Two distinct durable human class-switched memory B cell populations are induced by vaccination and infection

  Cory A. Perugino, et al., bioRxiv - Immunology 2024

  Quote: ... anti-human IgD (BioLegend, Clone IA6-2, BV785, 1:100, 37℃); anti-human-CD38 (BioLegend ...
• Spermidine/spermine N1-acetyltransferase controls tissue-specific regulatory T cell function in chronic inflammation

  Teresa Neuwirth, et al., bioRxiv - Immunology 2024

  Quote: ... Each patient was also stained with one of TotalSeq™-C0251/2/3/4 Antibody (Biolegend, Cat: 394661/3/5/7, 1:100) for sample multiplexing ...
• Single cell profiling of T and B cell repertoires following SARS-CoV-2 mRNA vaccine

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Lateral plate mesoderm cell-based organoid system for NK cell regeneration from human pluripotent stem cells

  Dehao Huang, et al., bioRxiv - Immunology 2021

  Quote: ... TRAIL (Biolegend, RIK-2), FasL (Biolegend ...
• The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

  Sumit Sen Santara, et al., bioRxiv - Immunology 2021

  Quote: ... 2 μM monensin (BioLegend) and 3 μM brefeldin A (BD ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 (Biolegend, #431004) and IL-22 (Biolegend ...
• Systemic and mucosal mobilization of granulocyte subsets during lentivirus infection

  Rhianna Jones, et al., bioRxiv - Immunology 2021

  Quote: ... CD32 (FUN-2; BioLegend), CD95 (DX2 ...
• Regeneration of humoral immunity from pluripotent stem cells by defined transcription factors

  Qi Zhang, et al., bioRxiv - Immunology 2021

  Quote: ... CD138(281-2, BioLegend), CD38(90 ...
• Deep immune profiling of the maternal-fetal interface with mild SARS-CoV-2 infection

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2021

  Quote: ... IgD (IA6-2, BioLegend), CD27 (M-T271 ...
• Novel Fas-TNFR chimeras that prevents Fas ligand-mediated kill and signals synergistically to enhance CAR T-cell efficacy

  Callum McKenzie, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... IL-2 (Biolegend; 431804), CCL1 (R&D Systems ...
• Integration of Avidity and Differentiation is enabled by CD8⁺ T-cell sensing of IFN-γ

  Lion F.K. Uhl, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (Biolegend, #575404), IL-1β (Biolegend ...
• Type I interferon dynamics determines memory B cell epigenetic identity in chronic viral infection

  Lucy Cooper, et al., bioRxiv - Immunology 2023

  Quote: ... or 2 (Biolegend #155863) for 20 minutes at 4°C ...
• Circulating mast cell progenitors migrate to atopic dermatitis-like skin then adapt locally

  Yuki Honda Keith, et al., bioRxiv - Immunology 2022

  Quote: ... integrinβ2 (M18/2; BioLegend), IgE (R35-72 ...
• Manufacturing CD20/CD19-targeted iCasp9 regulatable CAR-T_SCM cells using qCART, the Quantum pBac-based CAR-T system

  Peter S. Chang, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and IL-2 (BioLegend) were quantified by ELISA according to manufacturer’s instructions.
• Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

  Yuhao Shi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD8b.2 (Biolegend, 140416), Granzyme B (Biolegend ...
• Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells

  Joshua B. Perkins, et al., bioRxiv - Immunology 2024

  Quote: ... CD8a (Ly-2, BioLegend), and CCR6 (29-2L17 ...
• Impaired complement regulation drives chronic lung allograft dysfunction after lung transplantation

  Hrishikesh S. Kulkarni, et al., bioRxiv - Immunology 2024

  Quote: ... CD138 (281-2; Biolegend) CD38 (S21016F ...
• Granzyme K drives a newly-intentified pathway of complement activation

  Carlos A. Donado, et al., bioRxiv - Immunology 2024

  Quote: ... cells were sensitized with mouse IgG2a cell-type specific antibodies (HUVEC and THP-1: CD31, HEC7, Invitrogen, 2 μg; Fibroblasts: HLA-A,B,C, W6/32, Biolegend, 2 μg) or a mouse IgG2a isotype control (MG2a-53 ...
• The lncRNA landscape of cardiac resident macrophages and identification of Schlafenlnc as a regulator of macrophage migratory function

  Anne Dueck, et al., bioRxiv - Cell Biology 2022

  Quote: ... PI (1:100) and cell hashing antibodies (1:1000, #1 for heart, #2 for blood, Biolegend) and incubated for 30min protected from light ...
• The Alzheimer’s Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states

  Dalya Rosner, et al., bioRxiv - Neuroscience 2024

  Quote: ... Directly conjugated antibodies used were MDL-1-PE (Clone 14H4-1-2; 1:200; Biolegend # 371705), mouse IgG2b-PE isotype control (Clone MPC-11 ...