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551 - 600 of 2015 citations for 4' Bromo 3' fluoro 2 morpholinomethyl benzophenone since 2020

• Identification of HIV-Reservoir Cells with Reduced Susceptibility to Antibody-Dependent Immune Response

  Antonio Astorga-Gamaza, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CD32-PE-Cy7 (FUN-2, Biolegend), anti-CD3-PE-Cy5 (UCHT-1 ...
• Programming the lymph node immune response with Amphiphile-CpG induces potent cellular and humoral immunity following COVID-19 subunit vaccination in mice and non-human primates

  Lochana M. Seenappa, et al., bioRxiv - Immunology 2022

  Quote: ... IL-2 (BV421, clone: MQ1-17H12, BioLegend), IL-4 (PE ...
• Secreted filarial nematode galectins modulate host immune cells

  Hannah J. Loghry, et al., bioRxiv - Immunology 2022

  Quote: ... and IL-2 (20 ng/ml) (Biolegend)) for naïve T cells (Th0 ...
• Glutamine is essential for overcoming the immunosuppressive microenvironment in malignant salivary gland tumors

  Shuting Cao, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and mIL-2 (100 U/ml, Biolegend). Fresh media with escalating concentrations of glutamine were replenished every day for 3 days ...
• Berberine and obatoclax inhibit SARS-CoV-2 replication in primary human nasal epithelial cells in vitro

  Finny S. Varghese, et al., bioRxiv - Microbiology 2020

  Quote: ... blocked with 2% Normal Serum Block (BioLegend), 1% BSA ...
• Use of a MAIT activating ligand, 5-OP-RU, as a mucosal adjuvant in a murine model of Vibrio cholerae O1 vaccination

  Owen Jensen, et al., bioRxiv - Immunology 2022

  Quote: ... anti-CD138-BV605 (clone 281-2, Biolegend).
• Profile of Mycobacterium tuberculosis-specific CD4 T cells at the site of disease and blood in pericardial tuberculosis

  Elsa Du Bruyn, et al., bioRxiv - Immunology 2022

  Quote: ... IL-2 PE/Dazzle (MQ1-17H12, Biolegend), Mip-1β Alexa Fluor 488 (#24006 ...
• Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier

  Ngoc Lan Tran, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-CD18/ITGB2 (clone M18/2, Biolegend), anti-CD49d/ITGA4 (clone 9C10(MFR4.B) ...
• The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation

  Danielle Minns, et al., bioRxiv - Immunology 2020

  Quote: ... rIL-2 (40 U/ml; Biolegend, #575402), αIL-12 (5 μg/ml ...
• aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis

  Olivia Molinar-Inglis, et al., bioRxiv - Cell Biology 2021

  Quote: ... + 2 μL Annexin V FITC (BioLegend, #640906) and incubated at room temperature for 15 min ...
• Antibody repertoire and gene expression dynamics of diverse human B cell states during affinity maturation

  Hamish W King, et al., bioRxiv - Immunology 2020

  Quote: ... IgD-PerCP-Cy5.5 (clone IA6-2; BioLegend), and IgM-FITC (clone MHM-88 ...
• Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

  Ann-Kathrin Mattes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 40 ng/mL IL-2 (BioLegend). After 4 days a half-medium change was done adding fresh complete medium and cells were further cultured for 4 days ...
• Endothelial Caveolin-1 and CXCL10 promote transcellular migration of autoreactive T cells across the blood-brain barrier

  Troy N. Trevino, et al., bioRxiv - Immunology 2022

  Quote: ... 5 ng/mL IL-2 (Biolegend 575404) was added to media and cells were cultured another 2 days (Lutz et al. ...
• Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

  Shijie Jin, et al., bioRxiv - Neuroscience 2023

  Quote: ... with anti-CD81 (clone Eat-2, BioLegend), anti-HepaCAM (Affinity Biosciences ...
• Impact of cannabis use on immune cell populations and the viral reservoir in people with HIV on suppressive antiretroviral therapy

  Shane D. Falcinelli, et al., bioRxiv - Microbiology 2022

  Quote: ... IL-2-APC (MQ1-17H12 clone, Biolegend), TNFa-AF700 (Mab11 clone ...
• Human intestinal organoids with an autologous tissue-resident immune compartment

  Timothy Recaldin, et al., bioRxiv - Immunology 2023

  Quote: ... and IL-15 [2 ng/ml] (BioLegend), media change 3 times per week and culture splitting 1 time per week ...
• CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment

  Meenakshi Kar, et al., bioRxiv - Immunology 2024

  Quote: ... IL-2: BV605 (Biolegend, Clone: JES6-5H4), TNFα (Biolegend ...
• Enhanced Fc Receptor expression and distinct immunomodulatory properties of neutrophils during HIV-1 infection and therapy

  Soledad Marsile-Medun, et al., bioRxiv - Immunology 2024

  Quote: ... PE-CD32a/b (FUN-2, Biolegend #303206), PE-CD64 (10.1 ...
• Stiffness regulates dendritic cell and macrophage subtype development and increased stiffness induces a tumor-associated macrophage phenotype in cancer co-cultures

  Carla Guenther, bioRxiv - Immunology 2024

  Quote: ... and hCD206 (BioLegend, #321136, clone 15-2). Dead cells were stained with 2 μg/ml propidium iodide (Sigma ...
• AXL limits the mobilization of cholesterol to regulate dendritic cell maturation and the immunogenic response to cancer

  Meriem Belabed, et al., bioRxiv - Immunology 2023

  Quote: ... anti-human CD206 (clone 15-2, BioLegend), anti-human CD80 (clone W17149D ...
• Differentially polarized macrophages show diverse proangiogenic characteristics under normo- and hyperglycemic conditions

  Mahnaz Shariatzadeh, et al., bioRxiv - Immunology 2024

  Quote: ... and CD206 (MRC1)-FITC (15-2; BioLegend). After 20 minutes of incubation ...
• Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

  Alison Tarke, et al., bioRxiv - Immunology 2023

  Quote: ... CD8 BUV496 (2:100; Biolegend Cat#612942), CD14 V500 (2:100 ...
• Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy

  Kristen N. Haggerty, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-centrin-2 (BioLegend Cat# 698601, RRID:AB_2715793), anti-centrin-2 (Proteintech Cat# 15877-1-AP ...
• Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations

  Aisha Souquette, et al., bioRxiv - Immunology 2023

  Quote: ... Panel 2) CD11b-BV785 (Biolegend Cat. 301346), CD11c-PE/Cy7 (Biolegend Cat ...
• Vitamin A-treated natural killer cells reduce interferon-gamma production and support regulatory T cell differentiation

  Mingeum Jeong, et al., bioRxiv - Immunology 2022

  Quote: ... and 2 ng/ml TGF-ß1 (Biolegend). NK cells treated with atRA for 5 days were collected and cultured with naïve T cells at a ratio of 1:1 for 2 days ...
• Cellular iron governs the host response to malaria

  Sarah K. Wideman, et al., bioRxiv - Immunology 2023

  Quote: ... 25 U/mL IL-2 (575404, BioLegend) and 50 μM 2-Mercaptoethanol ...
• Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease-like ileitis

  Weili Xu, et al., bioRxiv - Immunology 2023

  Quote: ... 2 μg/ml anti-CD28 (37.5, Biolegend) and IEL supernatant described above ...
• On-chip human lymph node stromal network for evaluating dendritic cell and T-cell trafficking

  Brian J. Kwee, Adovi Akue, Kyung E. Sung, bioRxiv - Bioengineering 2023

  Quote: ... or 2 μM monensin (BioLegend, Cat. # 420701). After addition of DCs or T-cells to the device ...
• Therapeutic immune cell engineering with an mRNA : AAV-Sleeping Beauty composite system

  Lupeng Ye, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 200U/mL human IL-2 (BioLegend).
• Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function

  Branka Popović, et al., bioRxiv - Immunology 2022

  Quote: ... α-IL-2 (MQ1-17H12, all Biolegend), and α-TNF (MAb11 ...
• Therapeutic immune cell engineering with an mRNA : AAV-Sleeping Beauty composite system

  Lupeng Ye, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 400U/mL human IL-2 (BioLegend). T cells were activated with Dynabeads Human T-Activator CD3/CD28 (ThermoFisher ...
• Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2023

  Quote: ... and BCL-2-Alexa Fluor 647 (Biolegend). For experiments using the Proteasome Activity Probe (R&D) ...
• Artificial Intelligence Enables the Label-Free Identification of Chronic Myeloid Leukemia Cells with Mitochondrial Morphological Alterations

  Kohjin Suzuki, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ERK1/2 antibody (clone W15133B, BioLegend); anti-ERK1/2 phospho(Thr202/Tyr204 ...
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... and BCL-2-Alexa Fluor 647 (Biolegend) for 3 hours ...
• A viral-specific CD4⁺ T cell response protects female mice from Coxsackievirus B3 infection

  Aryamav Pattnaik, et al., bioRxiv - Immunology 2023

  Quote: ... CD49d (clone R1-2, BioLegend, catalog #103618).
• β-Glucan Reprograms Neutrophils to Induce Disease Tolerance Against Influenza A Virus

  Nargis Khan, et al., bioRxiv - Immunology 2024

  Quote: ... CD14 APC/Fire780 (clone Sa14- 2, Biolegend) in staining buffer (420201 ...
• Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy

  Lesia Semenova, et al., bioRxiv - Microbiology 2024

  Quote: ... IL-2-APC (MQ1-17H12 clone, Biolegend), TNFα-AF700 (Mab11 clone ...
• A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection

  Ningxin Kang, et al., bioRxiv - Immunology 2024

  Quote: ... 2 μl of FcR blocking reagent (Biolegend), and various combinations of anti-human CD19 PE-Cy7 (2 μl per test ...
• Tissue resident memory CD4⁺ T cells are sustained by site-specific levels of self-renewal and replacement from precursors

  Jodie Chandler, et al., bioRxiv - Immunology 2024

  Quote: ... CD8b.2-APC (53-5.8) (all BioLegend); TCRβ-PerCPCy5.5 (104 ...
• Affinity maturation of antibody responses is mediated by differential plasma cell proliferation

  Andrew J. MacLean, et al., bioRxiv - Immunology 2024

  Quote: ... Anti-mouse CD138 (218-2, Biolegend, 142518), Anti-mouse TACI (8F10 ...
• Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC

  Khalid N.M. Abdelazeem, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PE-IL-2 (Clone: JES6-5H4 Biolegend), BV 421-IL-10 (Clone ...
• Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC

  Khalid N.M. Abdelazeem, et al., bioRxiv - Cancer Biology 2024

  Quote: ... BV605-IL-2 (Clone: JES6-5H4 Biolegend), PE-IL-2 (Clone ...
• TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION

  Anthony C. Restaino, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and IL-2–Pacific Blue (BioLegend, 503820) to detect the production of key cytokines that indicate cellular activation and function ...
• Single-cell analyses of immune thrombocytopenic patients reveal multiorgan dissemination of high-affinity autoreactive plasma cells

  Pablo Canales-Herrerias, et al., bioRxiv - Immunology 2021

  Quote: ... cells were washed and resuspended at 2×106 in 100μl PBS with 2% FBS and incubated with Zombie violet fixable viability dye (Biolegend) and an antibody cocktail for 25min at 4°C in the dark ...
• Re-education of myeloid immune cells to reduce regulatory T cell expansion and impede breast cancer progression

  Hashni Epa Vidana Gamage, et al., bioRxiv - Cancer Biology 2023

  Quote: ... expanded CD4+ T cells were cocultured at different ratios with CFSE/CTV labeled CD8+ T cells and stimulated with Mouse T-Activator CD3/CD28 Dynabeads at 2 cells per bead ratio and 0.5ng/mL IL-2 (BioLegend). Cell culture media consisted with RPMI 1640 ...
• The meninges host a unique compartment of regulatory T cells that bulwarks adult hippocampal neurogenesis

  Miguel Marin-Rodero, et al., bioRxiv - Immunology 2024

  Quote: ... for the clone that binds to the high affinity IL-2 receptor (CD25): we incubated 0.5ugr mouse Il-2 (PepreoTech) to 5ugr of an IL-2 mAb (JES6-1A12, Biolegend) for 30 minutes on ice ...
• Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1

  Takeya Masubuchi, et al., bioRxiv - Immunology 2024

  Quote: ... The amount of IL-2 in the culture medium was measured using a mouse IL-2 ELISA kit (Biolegend).
• Three-step scalable production of extracellular vesicles from pancreatic beta cells in stirred tank bioreactors promotes cell maturation and release of ectosomes with preserved immunomodulatory properties

  Laurence de Beaurepaire, et al., bioRxiv - Bioengineering 2024

  Quote: ... APC- CD81 (clone Eat-2; 2 µg/mL) detection antibodies or isotypic controls (all antibodies were purchased from BioLegend). Flow cytometry was performed on a MACSQuant 10 instrument (Miltenyi Biotech ...
• Targeted Delivery of Chloroquine to Plasmacytoid Dendritic Cells Enhances Inhibition of the Type I Interferon Response

  Marilyn E. Allen, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 20 ng/mL recombinant human IL-3 (BioLegend; San Diego, CA, USA) to determine cellular distribution ...
• Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques

  Timothy N. Hoang, et al., bioRxiv - Immunology 2020

  Quote: ... and anti-IFNγ Alexa 647 (clone 4S.B3; 3 μL; cat# 502516) from Biolegend; anti-CD3 BV605 (clone SP34-2 ...