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451 - 500 of 1855 citations for 5 Methoxypyridine 2 carboxylic acid methyl ester since 2020

• Antibody repertoire and gene expression dynamics of diverse human B cell states during affinity maturation

  Hamish W King, et al., bioRxiv - Immunology 2020

  Quote: ... IgD-PerCP-Cy5.5 (clone IA6-2; BioLegend), and IgM-FITC (clone MHM-88 ...
• Vitamin A-treated natural killer cells reduce interferon-gamma production and support regulatory T cell differentiation

  Mingeum Jeong, et al., bioRxiv - Immunology 2022

  Quote: ... and 2 ng/ml TGF-ß1 (Biolegend). NK cells treated with atRA for 5 days were collected and cultured with naïve T cells at a ratio of 1:1 for 2 days ...
• Targets and cross-reactivity of human T cell recognition of Common Cold Coronaviruses

  Alison Tarke, et al., bioRxiv - Immunology 2023

  Quote: ... CD8 BUV496 (2:100; Biolegend Cat#612942), CD14 V500 (2:100 ...
• Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy

  Kristen N. Haggerty, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-centrin-2 (BioLegend Cat# 698601, RRID:AB_2715793), anti-centrin-2 (Proteintech Cat# 15877-1-AP ...
• Integrated Drivers of Basal and Acute Immunity in Diverse Human Populations

  Aisha Souquette, et al., bioRxiv - Immunology 2023

  Quote: ... Panel 2) CD11b-BV785 (Biolegend Cat. 301346), CD11c-PE/Cy7 (Biolegend Cat ...
• Artificial Intelligence Enables the Label-Free Identification of Chronic Myeloid Leukemia Cells with Mitochondrial Morphological Alterations

  Kohjin Suzuki, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-ERK1/2 antibody (clone W15133B, BioLegend); anti-ERK1/2 phospho(Thr202/Tyr204 ...
• Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease-like ileitis

  Weili Xu, et al., bioRxiv - Immunology 2023

  Quote: ... 2 μg/ml anti-CD28 (37.5, Biolegend) and IEL supernatant described above ...
• Cellular iron governs the host response to malaria

  Sarah K. Wideman, et al., bioRxiv - Immunology 2023

  Quote: ... 25 U/mL IL-2 (575404, BioLegend) and 50 μM 2-Mercaptoethanol ...
• AXL limits the mobilization of cholesterol to regulate dendritic cell maturation and the immunogenic response to cancer

  Meriem Belabed, et al., bioRxiv - Immunology 2023

  Quote: ... anti-human CD206 (clone 15-2, BioLegend), anti-human CD80 (clone W17149D ...
• CD4+ and CD8+ T cells are required to prevent SARS-CoV-2 persistence in the nasal compartment

  Meenakshi Kar, et al., bioRxiv - Immunology 2024

  Quote: ... IL-2: BV605 (Biolegend, Clone: JES6-5H4), TNFα (Biolegend ...
• Stiffness regulates dendritic cell and macrophage subtype development and increased stiffness induces a tumor-associated macrophage phenotype in cancer co-cultures

  Carla Guenther, bioRxiv - Immunology 2024

  Quote: ... and hCD206 (BioLegend, #321136, clone 15-2). Dead cells were stained with 2 μg/ml propidium iodide (Sigma ...
• Enhanced Fc Receptor expression and distinct immunomodulatory properties of neutrophils during HIV-1 infection and therapy

  Soledad Marsile-Medun, et al., bioRxiv - Immunology 2024

  Quote: ... PE-CD32a/b (FUN-2, Biolegend #303206), PE-CD64 (10.1 ...
• Differentially polarized macrophages show diverse proangiogenic characteristics under normo- and hyperglycemic conditions

  Mahnaz Shariatzadeh, et al., bioRxiv - Immunology 2024

  Quote: ... and CD206 (MRC1)-FITC (15-2; BioLegend). After 20 minutes of incubation ...
• A viral-specific CD4⁺ T cell response protects female mice from Coxsackievirus B3 infection

  Aryamav Pattnaik, et al., bioRxiv - Immunology 2023

  Quote: ... CD49d (clone R1-2, BioLegend, catalog #103618).
• Acetyl-CoA Carboxylase Obstructs CD8⁺ T-Cell Lipid Utilization and Energy Synthesis in the Tumor Microenvironment

  Elizabeth G. Hunt, et al., bioRxiv - Immunology 2023

  Quote: ... and BCL-2-Alexa Fluor 647 (Biolegend) for 3 hours ...
• Adaptive IRE1 Signaling Elicits T Cell Metabolic Remodeling and Tumor Control

  Brian P. Riesenberg, et al., bioRxiv - Immunology 2023

  Quote: ... and BCL-2-Alexa Fluor 647 (Biolegend). For experiments using the Proteasome Activity Probe (R&D) ...
• Human intestinal organoids with an autologous tissue-resident immune compartment

  Timothy Recaldin, et al., bioRxiv - Immunology 2023

  Quote: ... and IL-15 [2 ng/ml] (BioLegend), media change 3 times per week and culture splitting 1 time per week ...
• Complementary CRISPR screen highlights the contrasting role of membrane-bound and soluble ICAM-1 in regulating antigen specific tumor cell killing by cytotoxic T cells

  Ann-Kathrin Mattes, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and 40 ng/mL IL-2 (BioLegend). After 4 days a half-medium change was done adding fresh complete medium and cells were further cultured for 4 days ...
• Astroglial exosome HepaCAM signaling and ApoE antagonization coordinates early postnatal cortical pyramidal neuronal axon growth and dendritic spine formation

  Shijie Jin, et al., bioRxiv - Neuroscience 2023

  Quote: ... with anti-CD81 (clone Eat-2, BioLegend), anti-HepaCAM (Affinity Biosciences ...
• Impact of cannabis use on immune cell populations and the viral reservoir in people with HIV on suppressive antiretroviral therapy

  Shane D. Falcinelli, et al., bioRxiv - Microbiology 2022

  Quote: ... IL-2-APC (MQ1-17H12 clone, Biolegend), TNFa-AF700 (Mab11 clone ...
• On-chip human lymph node stromal network for evaluating dendritic cell and T-cell trafficking

  Brian J. Kwee, Adovi Akue, Kyung E. Sung, bioRxiv - Bioengineering 2023

  Quote: ... or 2 μM monensin (BioLegend, Cat. # 420701). After addition of DCs or T-cells to the device ...
• Therapeutic immune cell engineering with an mRNA : AAV-Sleeping Beauty composite system

  Lupeng Ye, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 200U/mL human IL-2 (BioLegend).
• Time-dependent regulation of cytokine production by RNA binding proteins defines T cell effector function

  Branka Popović, et al., bioRxiv - Immunology 2022

  Quote: ... α-IL-2 (MQ1-17H12, all Biolegend), and α-TNF (MAb11 ...
• Therapeutic immune cell engineering with an mRNA : AAV-Sleeping Beauty composite system

  Lupeng Ye, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 400U/mL human IL-2 (BioLegend). T cells were activated with Dynabeads Human T-Activator CD3/CD28 (ThermoFisher ...
• Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy

  Lesia Semenova, et al., bioRxiv - Microbiology 2024

  Quote: ... IL-2-APC (MQ1-17H12 clone, Biolegend), TNFα-AF700 (Mab11 clone ...
• Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

  Mikala C. Mueller, et al., bioRxiv - Bioengineering 2024

  Quote: ... 4′,6-diamidino-2-phenylindole (DAPI; BioLegend) was diluted 1:10,000 from a 5 mg mL-1 stock solution in deionized water ...
• β-Glucan Reprograms Neutrophils to Induce Disease Tolerance Against Influenza A Virus

  Nargis Khan, et al., bioRxiv - Immunology 2024

  Quote: ... CD14 APC/Fire780 (clone Sa14- 2, Biolegend) in staining buffer (420201 ...
• A novel method for characterizing cell-cell interactions at single-cell resolution reveals unique signatures in blood T cell-monocyte complexes during infection

  Ningxin Kang, et al., bioRxiv - Immunology 2024

  Quote: ... 2 μl of FcR blocking reagent (Biolegend), and various combinations of anti-human CD19 PE-Cy7 (2 μl per test ...
• Tissue resident memory CD4⁺ T cells are sustained by site-specific levels of self-renewal and replacement from precursors

  Jodie Chandler, et al., bioRxiv - Immunology 2024

  Quote: ... CD8b.2-APC (53-5.8) (all BioLegend); TCRβ-PerCPCy5.5 (104 ...
• Affinity maturation of antibody responses is mediated by differential plasma cell proliferation

  Andrew J. MacLean, et al., bioRxiv - Immunology 2024

  Quote: ... Anti-mouse CD138 (218-2, Biolegend, 142518), Anti-mouse TACI (8F10 ...
• TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION

  Anthony C. Restaino, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and IL-2–Pacific Blue (BioLegend, 503820) to detect the production of key cytokines that indicate cellular activation and function ...
• Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC

  Khalid N.M. Abdelazeem, et al., bioRxiv - Cancer Biology 2024

  Quote: ... PE-IL-2 (Clone: JES6-5H4 Biolegend), BV 421-IL-10 (Clone ...
• Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC

  Khalid N.M. Abdelazeem, et al., bioRxiv - Cancer Biology 2024

  Quote: ... BV605-IL-2 (Clone: JES6-5H4 Biolegend), PE-IL-2 (Clone ...
• Exometabolomic analysis of decidualizing human endometrial stromal and perivascular cells

  Sarah Harden, et al., bioRxiv - Systems Biology 2020

  Quote: ... up to 1×106 EnSC/100 µL of Magnetic Bead Buffer (0.5% BSA in PBS) were combined with 5 µL/1×106 cells phycoerythrin (PE) conjugated anti-human SUSD2 antibody (BioLegend, London, UK). After 20 min on ice ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... plates were coated at least 5 hours prior to use with 5 ug/ml plate-bound anti-CD3 antibody (clone OKT3; BioLegend, LEAF grade), which is then washed off with PBS ...
• Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

  Ling Zhou, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... 5 and 10 µM) for 5 days were collected and stained with FITC-CD41 and PE-CD42b (BioLegend, San Diego, CA, USA) antibodies for 15 min on ice in the dark ...
• Directing an mRNA-LNP vaccine toward lymph nodes improves humoral and cellular immunity against SARS-CoV-2

  David M. Francis, et al., bioRxiv - Immunology 2021

  Quote: ... 5% CO2 in the presence of brefeldin A (Biolegend) and monensin (Biolegend) ...
• MAIT cells are minimally responsive to Mycobacterium tuberculosis within granulomas, but are functionally impaired by SIV in a macaque model of SIV and Mtb co-infection

  Amy L. Ellis-Connell, et al., bioRxiv - Immunology 2020

  Quote: ... 5 μg/mL Brefeldin A (Biolegend; San Diego, CA), and CD107a-APC (Table 1) ...
• TLR7 ligation augments haematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling and enhanced differentiation

  Oscar A Peña, et al., bioRxiv - Cancer Biology 2020

  Quote: ... phycoerythrin-cyanine7– conjugated anti-CD45RA (HI100; BioLegend; 5 μl), Allophycocyanin-conjugated anti-CD10 (eBioCB-CALLA ...
• IL-31 uncouples skin inflammation from itch sensation in allergic dermatitis

  Marlys S. Fassett, et al., bioRxiv - Immunology 2021

  Quote: ... PE-Cy7-conjugated anti-mouse CD4 (Biolegend, RM4-5); APC-conjugated anti-mouse CD4 (BioLegend ...
• IL4-driven microglia modulate stress resilience through BDNF-dependent neurogenesis

  Jinqiang Zhang, et al., bioRxiv - Neuroscience 2020

  Quote: ... APC anti-mouse CD11b (5 µg/mL, Biolegend, USA), APC/Cyanine7 anti-mouse CD86 (1 µg/mL ...
• Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor to promote neutrophilic inflammation

  Mieko Tokano, et al., bioRxiv - Immunology 2022

  Quote: ... or anti-mouse CD40 Ab (5 μg/mL; BioLegend) plus ARL67156 (1 μM ...
• TGFβ receptor inhibition unleashes interferon-β production by tumor-associated macrophages and enhances radiotherapy efficacy

  Pauline Hamon, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-CD64 (clone X54-5/7.1) all from BioLegend. For cytokine staining ...
• A Multitrait Locus Regulates Sarbecovirus Pathogenesis

  Alexandra Schäfer, et al., bioRxiv - Microbiology 2022

  Quote: ... PE-Cy7 anti-CD64 (Clone X54-5/7.1, Biolegend), AF700 anti-MHCII (Clone M5/114.15.2 ...
• Amino acid availability acts as a metabolic rheostat to determine the magnitude of ILC2 responses

  Suzanne H. Hodge, et al., bioRxiv - Immunology 2022

  Quote: ... IL-5 (PE or APC, eBioscience; clone TRFK5, BioLegend), and IL-13 (Alexa Fluor 488 ...
• G307S DNAM-1 mutation exacerbates autoimmune encephalomyelitis via enhancing CD4⁺ T cell activation

  Rikito Murata, et al., bioRxiv - Immunology 2022

  Quote: ... BV510-conjugated anti-mouse CD4 (clone RM4-5, Biolegend), BB515-conjugated anti-mouse CD25 (clone PC61 ...
• Epithelial Plasticity and Innate Immune Activation Promote Lung Tissue Remodeling following Respiratory Viral Infection

  Andrew K. Beppu, et al., bioRxiv - Cell Biology 2022

  Quote: ... Chicken Polyclonal anti-Keratin 5 (1:500, BioLegend, 905901); Mouse monoclonal anti-eGFP AF488 conjugated (1:500 ...
• The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type-2 immunity-independent inhibition of food intake

  Hendrik J.P. van der Zande, et al., bioRxiv - Immunology 2020

  Quote: ... IL-5 (TRFK5) and IFN-γ (XMG1.2; both Biolegend).
• Protective mucosal immunity against SARS-CoV-2 after heterologous systemic RNA-mucosal adenoviral vector immunization

  Dennis Lapuente, et al., bioRxiv - Immunology 2021

  Quote: ... anti-CD4-SB600 (1:1000, clone RM4-5, BioLegend), anti-CD127-FITC (1:500 ...
• A stem-loop RNA RIG-I agonist confers prophylactic and therapeutic protection against acute and chronic SARS-CoV-2 infection in mice

  Tianyang Mao, et al., bioRxiv - Immunology 2021

  Quote: ... PE anti-mCD64 (X54-5/7.1) (1:200) (BioLegend), Brilliant Violet 711 anti-mSiglecF (E50-2440 ...