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451 - 500 of 7856 citations for 1 3 Fluorophenyl 5 oxopyrrolidine 3 carboxylic acid since 2020

• scRNA-seq reveals transcriptional dynamics of Encephalitozoon intestinalis parasites in human macrophages

  Pattana Jaroenlak, et al., bioRxiv - Microbiology 2024

  Quote: ... 1 μl of TotalSeq™ B anti-human hashtag antibodies 5-10 (BioLegend, USA) was added into the cell suspensions collected from each infection time point and incubated for 20 min at 4°C ...
• Disruption of Immune Responses By Type I Diabetes Exacerbates SARS-CoV-2 Mediated Lung Injury

  Sara Kass-Gergi, et al., bioRxiv - Immunology 2024

  Quote: ... PE/Cyanine7 anti-mouse CD64 (FcγRI) antibody (1:200, Biolegend, Clone X54-5/7.1), Brilliant Violet 711™ anti-mouse/human CD11b antibody (1:200 ...
• GDNF family receptor alpha-like (GFRAL) expression is restricted to the caudal brainstem

  Cecilia Hes, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and anti-mouse CD4 Alexa Fluor 700 (1:100, RM4-5, Biolegend, Cat. 100536). We used FlowJo v10.10 software (FlowJo ...
• Reprogramming the genome of M13 bacteriophage for all-in-one personalized cancer vaccine

  Shengnan Huang, et al., bioRxiv - Bioengineering 2024

  Quote: ... The cells were centrifuged at 500 g for 5 minutes and then redispersed in 100 μL FACS buffer (1% BSA in 1× PBS) containing Fc blocker (101320, Biolegend), SIINFEKL H-2Kb tetramer (PE ...
• Direct specification of lymphatic endothelium from non-venous angioblasts

  Irina-Elena Lupu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... for 5-minutes on ice and stained with PECAM1-BV605 (Biolegend, #102427, 1:1000, 100), CD45-FITC (Biolegend ...
• Interferon-γ driven differentiation of monocytes into PD-L1⁺ and MHC II⁺ macrophages and the frequency of Tim-3⁺ tumor-reactive CD8⁺ T cells within the tumor microenvironment predict a positive response to anti-PD-1-based therapy in tumor-bearing mice

  Jelena Gabrilo, et al., bioRxiv - Immunology 2024

  Quote: ... Five different TotalSeq-B antibodies were used in each experiment (Hashtag antibody 1-5, BioLegend). Incubation lasted for 30 min ...
• A CYCLIC PEPTIDE TARGETS GLIOBLASTOMA BY BINDING TO ABERRANTLY EXPOSED SNAP25

  Alberto G. Arias, et al., bioRxiv - Cancer Biology 2024

  Quote: ... in diluted blocking buffer (1/5 in PBS) or its isotype control (Biolegend, Cat # 400132) at 4°C overnight ...
• APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease

  Rosemary J Jackson, et al., bioRxiv - Neuroscience 2023

  Quote: ... Sections were then blocked in 5% NDS in TBS for 1 hour before being incubated with 1:1000 6E10 (BioLegend 803004) overnight at 4°C ...
• Shaping neonatal immunization by tuning delivery of synergistic adjuvants via nanocarriers

  Soumik Barman, et al., bioRxiv - Immunology 2022

  Quote: ... 5% CO2 and 5 μg/mL Brefeldin A (BFA; BioLegend) was added during the last 6 h of stimulation ...
• Obesity impairs therapeutic efficacy of mesenchymal stem cells by inhibiting cardiolipin-dependent mitophagy and intercellular mitochondrial transfer in mouse models of allergic airway inflammation

  Shakti Sagar, et al., bioRxiv - Cell Biology 2021

  Quote: ... IL-5 (BioLegend) and IL-13 (R&D Systems ...
• Loss of the adhesion protein Kindlin-1 stimulates tumor clearance via modulation of Tregs

  Emily R Webb, et al., bioRxiv - Cancer Biology 2022

  Quote: ... TGFß (1 ng/ml; cat#763102) and IL-2 (5 ng/ml, cat# 575402; All Biolegend) were added along with T cell media (RPMI ...
• Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR⁺NKG2A^- NK cells

  Sabrina Bianca Bennstein, et al., bioRxiv - Immunology 2020

  Quote: ... supernatant was collected at day 1 and 5 for LEGENDplexTM Human T Helper Cytokine Panel (BioLegend).
• Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

  Nikolaos Kakogiannos, et al., bioRxiv - Cell Biology 2022

  Quote: ... BV711 Mouse anti mouse CD64 (Monoclonal; clone X54-5/7.1; Biolegend; 1:100; Cat#139311, FACS). BV421 Rat anti mouse CD68 (Monoclonal ...
• A multi-enhancer hub at the Ets1 locus controls T cell differentiation and allergic inflammation through 3D genome topology

  Aditi Chandra, et al., bioRxiv - Genomics 2022

  Quote: ... and extracellular stains with anti-mouse CD4-APC (1:400, clone RM4-5, BioLegend Cat#100516), anti-mouse TCRb chain-FITC (1:400 ...
• Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and Mycobacterium tuberculosis Infection

  Rocky Lai, et al., bioRxiv - Immunology 2022

  Quote: ... cells were first stimulated for 5 hours with either anti-CD3 antibodies (1 ug/mL, Biolegend) or MTB300 peptide megapool (21 ...
• The PD-1 checkpoint receptor maintains tolerance of self-reactive CD8 T cell in skin

  Martina Damo, et al., bioRxiv - Immunology 2021

  Quote: ... 1-5 * 106 cells were stained with antibodies specific for surface markers Thy1.2 (clone 30-H12, BioLegend), Thy1.1 (clone OX-7 ...
• Loss of the adhesion protein Kindlin-1 stimulates tumor clearance via modulation of Tregs

  Emily R Webb, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Approximately 1×106 cells were aliquoted in 5 ml tubes and incubated with Fc Blocking antibody (Biolegend). Antibodies used for immune profiling are detailed in Supplementary Table 1 ...
• Direct specification of lymphatic endothelium from non-venous angioblasts

  Irina-Elena Lupu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... centrifuged and 500xg for 5 min and blocked with Fc block CD16/32 (Biolegend, #101302, 1:100), for 5-minutes on ice and stained with PECAM1-BV605 (Biolegend ...
• Sex differences in vaccine induced immunity and protection against Mycobacterium tuberculosis

  Gishnu Harikumar Parvathy, et al., bioRxiv - Immunology 2024

  Quote: ... cells were washed and incubated with fluorescently labeled antibodies (CD4 PE, clone RM4-5, 1:400, BioLegend; CD8a FITC ...
• Mapping the T cell repertoire to a complex gut bacterial community

  Kazuki Nagashima, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (RM4-5, BioLegend), CD3e (145-2C11 ...
• Disruption of Z-RNA–binding of ADAR1 induces Aicardi-Goutières syndrome–like encephalopathy in mice

  Taisuke Nakahama, et al., bioRxiv - Immunology 2020

  Quote: ... CD4 (RM4-5; BioLegend), CD8 (53-6.7 ...
• Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection

  Dan Corral, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD8a (53-6.7 ...
• 12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes

  Abhishek Kulkarni, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (RM4-5, Biolegend), CD80 (16-10A1 ...
• Phosphoproteomic analysis of the AKT signalling axis in cutaneous squamous carcinoma progression reveals novel therapeutic targets

  R Button, C Harwood, RFL O’Shaughnessy, bioRxiv - Cancer Biology 2022

  Quote: ... Keratin 5 (BioLegend Poly19055) (1:1,000 WB) ...
• Secreted Particle Information Transfer (SPIT) – A Cellular Platform for In Vivo Genetic Engineering

  Carsten T. Charlesworth, et al., bioRxiv - Synthetic Biology 2024

  Quote: ... CD4 (RM4-5; Biolegend), CD8 (54-6.7 ...
• IL-6 prevents Th2 cell polarization by promoting SOCS3-dependent suppression of IL-2 signaling

  Holly Bachus, et al., bioRxiv - Immunology 2022

  Quote: ... IL-5 (TRFK5; BioLegend), IL-4 (11B11 ...
• Atheroprone shear stress stimulates noxious endothelial extracellular vesicle uptake by MCAM and PECAM-1 cell adhesion molecules

  Pierre-Michaël Coly, et al., bioRxiv - Cell Biology 2023

  Quote: ... α5 integrin (Biolegend, 921704), α6 integrin (Biolegend ...
• CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

  Amélien Sanlaville, et al., bioRxiv - Cancer Biology 2023

  Quote: ... CD4 (RM4-5; Biolegend), NKp46 (29A1.4 ...
• Sexual dimorphism in obesity is governed by RELMα regulation of adipose macrophages and eosinophils

  Jiang Li, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD206 (C068C2 ...
• Interferon-γ Elicits Pathological Hallmarks of ALS in Human Motor Neurons

  Changho Chun, et al., bioRxiv - Neuroscience 2023

  Quote: ... CD44 (C44Mab-5, BioLegend), and CD8 (SK1 ...
• A ketogenic diet reduces age-induced chronic neuroinflammation in mice

  Mitsunori Nomura, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, BioLegend), CD8 (53-6.7 ...
• Soquelitinib, A Selective Inhibitor of Interleukin-2-Inducible T Cell Kinase (ITK), is Active in Several Murine Models of T Cell-Mediated Inflammatory Disease

  Lih-Yun Hsu, et al., bioRxiv - Immunology 2023

  Quote: ... CD4 (RM4-5, Biolegend), CD44 (IM7 ...
• Interferon-sensitized hematopoietic progenitors dynamically alter organismal immunity

  Maria Guillamot, et al., bioRxiv - Immunology 2024

  Quote: ... CD4 (Biolegend RM4/5), CD8 (Biolegend ...
• The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis

  Christiane Pleuger, et al., bioRxiv - Immunology 2022

  Quote: ... table 1) were diluted in blocking solution (F4/80 [Bio-Rad]: 10 µg/ml, Ly6G [abcam]: 1 µg/ml, MHC-II [BioLegend]: 5 µg/ml), CD163 [Invitrogen] ...
• Molecular programs of fibrotic change in aging human lung

  Jasmine Lee, et al., bioRxiv - Genomics 2021

  Quote: ... 5% normal goat serum in PBS for 1 hour and incubated at 4°C overnight with primary antibody (Biolegend, cat. 613402, dilution 1:500), then at room temperature for 3 hours with secondary antibody (Santa Cruz Biotechnology ...
• Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy

  Nipun Verma, et al., bioRxiv - Genetics 2024

  Quote: Cell cycle analysis was performed using DAPI nucleic acid dye (Biolegend #422801). 1 day after passaging ...
• Tau in cerebrospinal fluid induces neuronal hyperexcitability and alters hippocampal theta oscillations

  Jessica Brown, et al., bioRxiv - Neuroscience 2023

  Quote: ... Four μg of Tau12 (N-terminal [epitope = amino acids 6-18], BioLegend), HT7 (mid-region [epitope = amino acids 159-163] ...
• Maternal Western-Style Diet Impairs Bone Marrow Development and Drives a Hyperinflammatory Phenotype in Hematopoietic Stem and Progenitor Cells in Fetal Rhesus Macaques

  Suhas Sureshchandra, et al., bioRxiv - Immunology 2022

  Quote: ... 5×105-1×106 cells were stained with antibodies to CD45 (D058-1283, Biolegend, San Diego, CSA, USA), CD3 (clone SP34 ...
• Pdap1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

  Verónica Delgado-Benito, et al., bioRxiv - Immunology 2020

  Quote: CH12 cells were stimulated to undergo CSR to IgA by treatment with 1-5 μg/mL αCD40 (BioLegend), 5 ng/ml TGFβ (R&D Systems ...
• Endothelial Caveolin-1 and CXCL10 promote transcellular migration of autoreactive T cells across the blood-brain barrier

  Troy N. Trevino, et al., bioRxiv - Immunology 2022

  Quote: ... were injected into the microfluidic circulation in HBSS with 1% FBS supplemented with 5 nM CXCL10 (Biolegend 573604) or vehicle (PBS) ...
• The up-regulation of TGF-β1 by miRNA-132-3p/WT1 is involved in inducing leukemia cells to differentiate into macrophages

  Zhimin Wang, et al., bioRxiv - Immunology 2024

  Quote: ... 5 μl PE-labeled mouse anti-human CD11b fluorescent antibody (cat. no. 301306; 1:1,000 dilution; BioLegend, Inc.) or FITC-labeled mouse anti human CD14 fluorescent antibody (cat ...
• Tissue environment, not ontogeny, defines intestinal intraepithelial T lymphocytes

  Alejandro Brenes, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 [clone RM4-5 (BioLegend)] ...
• A third vaccination with a single T cell epitope protects against SARS-CoV-2 infection in the absence of neutralizing antibodies

  Iris N. Pardieck, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 (clone RM4-5, BioLegend), CD8 (clone 53-6.7 ...
• Comprehensive proteomics analyses identify PIM kinases as key regulators of IL-15 driven activation of intestinal intraepithelial lymphocytes

  Olivia J. James, et al., bioRxiv - Immunology 2020

  Quote: ... CD4 [clone RM4-5 (BioLegend)] ...
• NLRP1B and NLRP3 control the host response following colonization with the commensal protist Tritrichomonas musculis

  Pailin Chiaranunt, et al., bioRxiv - Immunology 2021

  Quote: ... CD64 (X54-5/7.1; BioLegend), and MHCII (I-A/I-E ...
• Opposing roles of Granzymes A and B in the immune response to intestinal infection

  Maud Vandereyken, et al., bioRxiv - Immunology 2021

  Quote: ... CD4 [clone RM4-5 (BioLegend)] ...
• IRF4 deficiency vulnerates B cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity

  Dennis Das Gupta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-CD2 (RM2-5, Biolegend), anti-CXCR4 (L276F12 ...
• IRF4 deficiency vulnerates B cell progeny for leukemogenesis via somatically acquired Jak3 mutations conferring IL-7 hypersensitivity

  Dennis Das Gupta, et al., bioRxiv - Cancer Biology 2022

  Quote: ... anti-CD43 (RM2-5, Biolegend), anti-CD24 (M1/69 ...
• Single-cell transcriptomic profile reveals macrophage heterogeneity in medulloblastoma and their treatment-dependent recruitment

  Mai T. Dang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... CD11b (BioLegend, clone CBRM1/5), Ly6C (BioLegend ...
• Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

  Valentina Stolz, et al., bioRxiv - Immunology 2022

  Quote: ... CD4 (clone: RM4-5, Biolegend), CD44 (clone ...