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151 - 180 of 180 citations since 2020

• Connexin 43 confers chemoresistance through activating PI3K

  Kevin J Pridham, et al., bioRxiv - Cancer Biology 2020

  Quote: ... TGX-221 (AdooQ Bioscience) were reconstituted in dimethyl sulfoxide (DMSO ...
• Gravin-associated kinase signaling networks coordinate γ-tubulin organization at mitotic spindle poles

  Paula J. Bucko, et al., bioRxiv - Cell Biology 2020

  Quote: ... BI2536 (AdooQ) and CLP-BI2536 (26 ...
• Adipocyte REVERBα dictates adipose tissue expansion during obesity

  A. Louise Hunter, et al., bioRxiv - Physiology 2020

  Quote: ... 1µM rosiglitazone (AdooQ Bioscience) and 0.5mM IBMX (Sigma-Aldrich ...
• Influenza-induced oxidative stress sensitizes lung cells to bacterial toxin-mediated necroptosis

  Norberto Gonzalez-Juarbe, et al., bioRxiv - Microbiology 2020

  Quote: ... and Pimodivir (AdooQ Bioscience, Irvine, CA). Cells receiving inhibitors were treated continuously beginning 1-hour prior to IAV infection ...
• Resetting proteostasis with ISRIB prevents pulmonary fibrosis

  Satoshi Watanabe, et al., bioRxiv - Immunology 2020

  Quote: ... ISRIB (AdooQ BioScience, A14302) was first reconstituted in DMSO to the concentration 4 mg/ml ...
• Pyronaridine Tetraphosphate Efficacy Against Ebola Virus Infection in Guinea Pig

  Thomas R. Lane, et al., bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... Favipiravir was purchased from AdooQ Bioscience (Irvine ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... The following drugs and chemicals were used: ABT-199/venetoclax (AdooQ BioScience, A12500-50), ABT-263 (ApexBio ...
• Apoptosis-induced FGF signalling promotes non-cell autonomous resistance to cell death

  Florian J. Bock, et al., bioRxiv - Cell Biology 2020

  Quote: ... qVD-oph (AdooQ BioScience, A14915-25), Rapamycin (Santa Cruz ...
• AMPKα1 is essential for Glucocorticoid Receptor triggered anti-inflammatory macrophage activation

  Giorgio Caratti, et al., bioRxiv - Physiology 2020

  Quote: ... cells were treated with MK-2206 (Adooq Bioscience, A10003, 1 μM) (or 0.01% of DMSO for controls ...
• Potentiation of Long-Acting β₂-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP

  Yechan Kim, et al., bioRxiv - Immunology 2020

  Quote: ... and cilomilast [CM] (AdooQ Bioscience, California, USA) were used for PDE4 inhibition ...
• Analyzing cannabinoid-induced abnormal behavior in a zebrafish model

  Akihiro Hasumi, Hideyuki Maeda, Ken-ichi Yoshida, bioRxiv - Pharmacology and Toxicology 2020

  Quote: ... WIN (Adooq Bioscience, Irvine, CA) was diluted with 0.05% dimethyl sulfoxide (Dojindo Laboratories ...
• Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold

  Nina Schweizer, et al., bioRxiv - Cell Biology 2020

  Quote: ... PLK1 was inhibited with 100 nM BI2536 (Adooq Bioscience).
• Synthetic protein condensates that recruit and release protein activity in living cells

  Tatsuyuki Yoshii, et al., bioRxiv - Synthetic Biology 2020

  Quote: ... cells were preincubated with PD184352 (50 μM) (AdooQ BioScience) for 1 h before rapamycin addition.
• Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly

  Takumi Chinen, et al., bioRxiv - Cell Biology 2020

  Quote: ... BI2536 (PLK1 inhibitor, A10134; AdooQ), proTAME (APC/C inhibitor ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for the first only day ...
• RIPK2 dictates insulin responses to tyrosine kinase inhibitors in obese mice

  Brittany M. Duggan, et al., bioRxiv - Physiology 2020

  Quote: ... Imatinib was from AdooQ Bioscience (Irvine ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for two days ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for the first only day ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for the first only day ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for the first only day ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for the first only day ...
• Defining the signalling determinants of a posterior ventral spinal cord identity in human neuromesodermal progenitor derivatives

  Matthew Wind, et al., bioRxiv - Developmental Biology 2020

  Quote: ... and ROCK inhibitor Y-27632 (10 µM, Adooq Biosciences) for the first only day ...
• Inflammation promotes adipocyte lipolysis via IRE1 kinase

  Kevin P. Foley, et al., bioRxiv - Physiology 2020

  Quote: ... Ponatinib (#A10080) and imatinib mesylate (imatinib; #A10468) were obtained from AdooQ Bioscience (Irvine ...
• In vitro pancreatic islet cluster expansion facilitated by hormones and chemicals

  Jing-Yu Lin, et al., bioRxiv - Cell Biology 2020

  Quote: ... 250 nM 5-Iodotubercidin (Adooq Bioscience), 50 ng/ml FGF10 (PeproTech) ...
• Rational design of a new class of protease inhibitors for the potential treatment of coronavirus diseases

  Michael Westberg, et al., bioRxiv - Biochemistry 2020

  Quote: ... narlaprevir (AdooQ, ≥ 98%), telaprevir (AdooQ Bioscience ...
• Obesity-Activated Lung Stomal Cells Promote Myeloid-Lineage Cell Accumulation and Breast Cancer Metastasis

  Lauren E. Hillers-Ziemer, et al., bioRxiv - Cancer Biology 2020

  Quote: ... lung stromal cells from LFD-fed mice were grown in 5% serum collected from LFD or HFD-fed mice supplemented with 10 μM of TGFβ inhibitor SB431542 (A10826A, Adooq Biosciences) or DMSO control or in DMEM +0.5% calf serum supplemented with 5 ng/mL recombinant mouse TGFβ1 (7666-MB ...
• Preclinical characterization of mobocertinib highlights the putative therapeutic window of this novel EGFR inhibitor to EGFR exon 20 insertion mutations

  Pedro E. N. S. Vasconcelos, et al., bioRxiv - Cancer Biology 2020

  Quote: ... poziotinib (AdooQ BioScience) and mobocertinib (MedChemExpress ...
• Connexin 43 confers chemoresistance through activating PI3K

  Kevin J Pridham, et al., bioRxiv - Cancer Biology 2020

  Quote: ... GSK2636771 (AdooQ Bioscience), TGX-221 (AdooQ Bioscience ...
• Foam cell induction activates AMPK but uncouples its regulation of autophagy and lysosomal homeostasis

  Nicholas D. LeBlond, et al., bioRxiv - Cell Biology 2020

  Quote: ... A-769662 (AdooQ Bioscience – 844499-71-4), Acetylated LDL (Alfa Aesar - J65029) ...
• Evidence for the plant recruitment of beneficial microbes to suppress soil-borne pathogen

  Hongwei Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... selective medium (32 mg L-1 Imipenem added, Adooq Biosciences) (Bollet et al. ...