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2201 - 2250 of 7738 citations for 6 Methylimidazo 1 2 a pyridine 3 carbaldehyde since 2019

• The Formation of a Stable Sliding Clamp Discriminates MSH2-MSH3 and MSH2-MSH6 Mismatch Interaction

  Brooke M. Britton, et al., bioRxiv - Biochemistry 2021

  Quote: ... 1 nM anti-dig (Roche), and stated [NaCl] ...
• Insights into calcium signaling and gene expression in astrocytes uncovered with 129S4 Slc1a3-2A-CreERT2 knock-in mice

  Lech Kaczmarczyk, et al., bioRxiv - Neuroscience 2020

  Quote: ... 1:100 (Roche, RRID: AB_390919), RPS21 1:100 (Bethyl ...
• Expression of mini-G proteins specifically halt cognate GPCR trafficking and intracellular signalling

  Yusman Manchanda, et al., bioRxiv - Cell Biology 2021

  Quote: ... with 1% protease inhibitor (Roche) and 1% phosphatase inhibitor cocktail (Sigma-Aldrich) ...
• ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1

  Cyril Statzer, et al., bioRxiv - Physiology 2021

  Quote: ... GFP (1:1’000, Roche #11814460001), Cystathionase/CTH (1:2000 ...
• Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation

  Jibin Sadasivan, et al., bioRxiv - Microbiology 2022

  Quote: ... α-GFP (1:1000, Roche). α-CrPV-VP2 (1:1000 ...
• DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments

  Max A. B. Haase, et al., bioRxiv - Genetics 2022

  Quote: ... and 1 protease tablet (Roche) and lysed with a French press ...
• Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

  Robert Jansen, et al., bioRxiv - Microbiology 2019

  Quote: ... and 1 mM NADH (Roche) at 37°C in triplicate ...
• LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is altered in Townes-Brocks Syndrome

  Laura Bozal-Basterra, et al., bioRxiv - Cell Biology 2019

  Quote: ... anti-GFP (Roche, 1:1,000), anti-GAPDH (Proteintech ...
• A dCas9/CRISPR-based targeting system identifies a central role for Ctf19 in kinetochore-derived suppression of meiotic recombination

  Lisa-Marie Kuhl, et al., bioRxiv - Genetics 2020

  Quote: ... α-GFP (Roche; 1:1000).
• Mitotic spindle assembly is controlled by the APC/C localized at the centrosome

  Thomas Tischer, Jing Yang, David Barford, bioRxiv - Cell Biology 2020

  Quote: ... GFP (Roche 11814460001, 1:1000), Cep57 (Genetex GTX115931 ...
• Synergy and allostery in ligand binding by HIV-1 Nef

  Abdullah Aldehaiman, et al., bioRxiv - Biophysics 2020

  Quote: ... 1 tablet protease inhibitor (Roche), 1% triton and 0.4 mg/ml lysozyme ...
• The lonely fish is not a loner fish: whole-brain mapping reveals abnormal activity in socially isolated zebrafish

  Hande Tunbak, et al., bioRxiv - Neuroscience 2020

  Quote: ... Fab fragments (Roche, 1:3000) and TSA Plus Cyanine 3 System (Perkin Elmer ...
• Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation

  Alexander Buschle, et al., bioRxiv - Cell Biology 2019

  Quote: ... 1 × proteinase inhibitor cocktail (Roche)) ...
• Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival

  Oana Kubinyecz, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1 mM dNTP mix (Roche)) and incubated on a thermocycler for 60 min at 42°C ...
• The ubiquitin ligase HOIL-1L regulates immune responses by interacting with linear ubiquitin chains

  Carlos Gomez-Diaz, et al., bioRxiv - Cell Biology 2021

  Quote: ... 1 mM PMSF (Roche, 10837091001) and 10 mM NEM (Sigma-Aldrich ...
• An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

  Molly M. Wilson, et al., bioRxiv - Cell Biology 2020

  Quote: ... HA (Roche 11867423001, 1:1000), RFP (Rockland 600-401-379S ...
• Dynamic assembly of the calcium hemostasis modulator 1 channel gates ATP permeation

  Yue Ren, et al., bioRxiv - Biochemistry 2021

  Quote: ... 1× protease inhibitor cocktail (Roche), and solubilized in 1% (w/v ...
• Chromatin accessibility analysis uncovers regulatory element landscape in prostate cancer progression

  Joonas Uusi-Mäkelä, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 1× protease inhibitors (Roche, cOmplete)) was added to pre-cooled petri dish and sections were moved from tube to petri dish with 1 ml of lysis buffer ...
• Protein kinase signalling at the Leishmania kinetochore captured by XL-BioID

  Vincent Geoghegan, et al., bioRxiv - Biochemistry 2021

  Quote: ... and 1 tablet PhosSTOP (Roche). Lysates were sonicated with a microtip sonicator on ice for 3 rounds of 10 seconds each at an amplitude of 30 ...
• The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex

  Mashun Onishi, Koji Okamoto, bioRxiv - Cell Biology 2021

  Quote: ... GFP (1:1000, Roche, 13921700), HA (1:5,000 ...
• Galectin-8 senses phagosomal damage and recruits selective autophagy adapter TAX1BP1 to control Mycobacterium tuberculosis infection in macrophages

  Samantha L. Bell, et al., bioRxiv - Microbiology 2020

  Quote: ... HA (Roche, 11867423001; 1:1000), LC3 (Invitrogen ...
• Targeted high-resolution chromosome conformation capture at genome-wide scale

  Damien J. Downes, et al., bioRxiv - Genomics 2020

  Quote: ... 1× cOmplete protease inhibitor (Roche) then pelleted by centrifugation (15 min ...
• Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription

  Fang Wang, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 1× Proteinase Inhibitor Cocktail (Roche) and 50 mM PR-619 DUB inhibitor (UBPBio) ...
• Cleavage of 14-3-3ε by the enteroviral 3C protease dampens RIG-I mediated antiviral signaling

  Daniel D.T. Andrews, et al., bioRxiv - Microbiology 2022

  Quote: ... 1:2000 GFP (Roche 11814460001).
• The extracellular matrix protein fibronectin modulates metanephric kidney development

  Kathrin Skoczynski, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 1% protease inhibitor mixture (Roche, cOmplete ...
• ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling

  Matteo Gentili, et al., bioRxiv - Immunology 2022

  Quote: ... 1% Nonidet-P40 Substitute (Roche) and 50mM NaCl (Thermo Fisher) ...
• linc-mipep and linc-wrb encode micropeptides that regulate chromatin accessibility in vertebrate-specific neural cells

  Valerie A. Tornini, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 1× protease inhibitors (Roche, cOmplete), and 167 μM β-mercaptoethanol ...
• Ralstonia solanacearum effector RipAF1 ADP-ribosylates host FBN1 to induce resistance against bacterial wilt

  Wei Wu, et al., bioRxiv - Plant Biology 2022

  Quote: ... and 1×phosphatase tablet (Roche). The homogenate was centrifuged at 15,000 × g for 20 min ...
• Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes

  Julien Racle, et al., bioRxiv - Immunology 2022

  Quote: ... 1×complete protease inhibitors (Roche)) with 100 µM peptide at 37°C for 24 hours ...
• A Synaptic Corollary Discharge Signal Suppresses Midbrain Visual Processing During Saccade-Like Locomotion

  Mir Ahsan Ali, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1% blocking reagent (Roche, 11096176001), 1% bovine serum albumin (Sigma ...
• TurboID reveals the proxiomes of CGE1, VIPP1, and VIPP2 in Chlamydomonas reinhardtii

  Elena Kreis, et al., bioRxiv - Plant Biology 2022

  Quote: ... 1× protease inhibitor cocktail (Roche), 1 mM phenylmethylsulfonyl fluoride (PMSF)) ...
• USP50 suppresses alternative RecQ helicase use and deleterious DNA2 activity during replication

  Hannah L. Mackay, et al., bioRxiv - Cancer Biology 2024

  Quote: ... 1 phosphatase tablet (PhosSTOP – Roche), 20 μM MG132 ...
• 3D-multiple immunoimaging using whole male organs in rice

  Saori Araki, Hinako Tamotsu, Reina Komiya, bioRxiv - Plant Biology 2022

  Quote: ... 1 mM Pefabloc SC (Roche), 1X Complete Protease Inhibitor Cocktail) ...
• SUMO2 Protects Against Tau-induced Synaptic and Cognitive Dysfunction

  Franca Orsini, et al., bioRxiv - Neuroscience 2022

  Quote: ... 1% phosphatase inhibitor cocktail (Roche) and 1 mM phenylmethylsulfonyl fluoride (PMSF) ...
• Converting antimicrobial into targeting peptides reveals key features governing protein import into mitochondria and chloroplasts

  Oliver D Caspari, et al., bioRxiv - Plant Biology 2022

  Quote: ... 20μl boiling buffer (1× Roche cOmplete™ Mini proteinase inhibitor cocktail ...
• Spatial control of ARGONAUTE-mediated RNA silencing in anther development

  Hinako Tamotsu, et al., bioRxiv - Plant Biology 2022

  Quote: ... 1 mM Pefabloc SC (Roche), 1× Complete Protease Inhibitor Cocktail (Roche)) ...
• Prevotella copri-related effects of a therapeutic food for malnutrition

  Hao-Wei Chang, et al., bioRxiv - Microbiology 2023

  Quote: ... and 1× protease inhibitor (Roche)] ...
• Thg1 family 3’-5’ RNA polymerases as tools for targeted RNA synthesis

  Malithi I. Jayasinghe, et al., bioRxiv - Biochemistry 2024

  Quote: ... 1 μg inorganic pyrophosphatase (Roche), 4 mM CTP/GTP/UTP ...
• Mechanistic basis of gene-specific transcription regulation by the Integrator complex

  Kevin Sabath, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 1×PhosSTOP phosphatase inhibitor (Roche), 5 µg/mL DNase I (AppliChem ...
• Mechanistic dissection of the CHD4 enhancers reveals cooperative functions among the homotypic ZNF410 clustered motifs

  Siyuan Xu, et al., bioRxiv - Molecular Biology 2024

  Quote: ... with 1 × protease inhibitors (Roche) and 1 × phenylmethylsulfonyl fluoride (PMSF ...
• Polyglutamylation of microtubules drives neuronal remodeling

  Antoneta Gavoci, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1 % NP-40 (Roche, #11332473001), 1 X Dithiothreitol (DTT ...
• Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development

  Avnish Patel, et al., bioRxiv - Molecular Biology 2024

  Quote: ... with 1× protease inhibitors (Roche). Samples were gently vortexed and incubated on ice for 10 min followed by centrifugation at 12,000g for 10 min at 4°C ...
• Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development

  Avnish Patel, et al., bioRxiv - Molecular Biology 2024

  Quote: ... with 1× protease inhibitors (Roche). Samples were gently vortexed and incubated on ice for 10 min followed by centrifugation at 12,000g for 10 min at 4°C ...
• Clinically relevant humanized mouse models of metastatic prostate cancer to evaluate cancer therapies

  Raymond J. Kostlan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1× protease inhibitor cocktail (Roche Molecular Biochemicals ...
• Maternal SMARCA5 is required for major ZGA in mouse embryos

  Oana Nicoleta Kubinyecz, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 mM dNTP mix (Roche)] and incubated on a thermocycler for 60 min at 42°C ...
• Maternal SMARCA5 is required for major ZGA in mouse embryos

  Oana Nicoleta Kubinyecz, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 1 mM dNTP mix (Roche)] for 60 min at 42°C ...
• Orai mediated Calcium entry determines activity of central dopaminergic neurons by regulation of gene expression

  Rishav Mitra, Shlesha Richhariya, Gaiti Hasan, bioRxiv - Neuroscience 2023

  Quote: ... 1× Protease inhibitor cocktail (Roche)] ...
• The role of BST4 in the pyrenoid of Chlamydomonas reinhardtii

  Liat Adler, et al., bioRxiv - Plant Biology 2023

  Quote: ... 1 x Protease inhibitor (Roche)) was added and samples vortexed for 30 s ...
• Development of a fluorescence reporter system to quantify transcriptional activity of endogenous p53 in living cells

  Tatsuki Tsuruoka, et al., bioRxiv - Cell Biology 2022

  Quote: ... the cells were seeded onto a 35 mm dish and treated with 0.5 μg/ml puromycin (Invivogen)/1 mg/ml G418 (Roche) for more than 14 days ...
• A conserved microtubule-binding region in Xanthomonas XopL is indispensable for induced plant cell death reactions

  Simon Ortmann, et al., bioRxiv - Pathology 2023

  Quote: ... α-GFP (1:2000, Roche diagnostics) at 1:2000 ...