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701 - 750 of 5389 citations for 2 Chloro 1 1 trifluoromethyl 1 3 4 9 tetrahydro 2H beta carbolin 2 yl ethan 1 one since 2020

• Harnessing PROTAC technology to combat stress hormone receptor activation

  Mahshid Gazorpak, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GAPDH (ABS16, Merck Millipore, 1:1000), HA (C29F4 ...
• Expression and engineering of unexplored PET degrading enzymes from Microbispora, Nonomuraea, Micromonospora genus

  Elaine Tiong, et al., bioRxiv - Microbiology 2023

  Quote: 1 mL overnight autoinduction media (Merck) was used for the inoculation of single colonies obtained from the transformation ...
• LptM promotes oxidative maturation of the lipopolysaccharide translocon by substrate binding mimicry

  Yiying Yang, et al., bioRxiv - Microbiology 2023

  Quote: ... or 1% (w/v) digitonin (Merck). After a clarifying spin to remove insoluble material ...
• EphrinA5 regulates cell motility by modulating the targeting of DNMT1 to the Ncam1 promoter via lncRNA/DNA triplex formation

  Can Bora Yildiz, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 1% protease inhibitor cocktail (#I3786, Merck)) ...
• Epigenetic mechanisms to propagate histone acetylation by p300/CBP

  Masaki Kikuchi, et al., bioRxiv - Biochemistry 2023

  Quote: ... H3K23ac (Merck, 07-355, 1/1,000), H3K27ac (Merck ...
• PAK1-dependant mechanotransduction enables myofibroblast nuclear adaptation and chromatin organisation during fibrosis

  Elliot Jokl, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-SOX9 (ab5535, Merck, 1:1000), anti-YAP (#4912 ...
• Metabolism-dependent secondary effect of anti-MAPK cancer therapy on DNA repair

  Fabien Aubé, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 1 mM ENU (+ENU, N3385, Merck), or 1 mM ENU + 1 µM vemurafenib/cobimetinib (+ENU+MAPKi) ...
• Oryza genera-specific novel Histone H4 variant predisposes H4 Lysine5 Acetylation marks to modulate salt stress responses

  Hari Sundar G Vivek, et al., bioRxiv - Plant Biology 2023

  Quote: ... α-H3 (Merck 07-10254, 1:20000), α-H4 (Abcam ab10158 ...
• Exploiting Epigenetic Targets to Overcome Taxane Resistance in Prostate Cancer

  Buse Cevatemre, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 1 mM PMSF (Merck, 10837091001). The cell suspension then was divided equally and heated for 3 min at indicated temperatures on T100™ Thermal Cycler (Bio-Rad Laboratories) ...
• New AAV9 engineered variants with enhanced neurotropism and reduced liver off-targeting in mice and marmosets

  Serena Gea Giannelli, et al., bioRxiv - Bioengineering 2023

  Quote: ... rabbit anti-NeuN (1:500; Merck), rabbit-Sox9 (1:500 ...
• Age-dependent NMDA receptor function is regulated by the Amyloid Precursor Protein

  Joana Rajão-Saraiva, et al., bioRxiv - Neuroscience 2022

  Quote: ... Synaptophysin (1:200, S5768, Merck Millipore), β-actin (1 :1000 ...
• Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells

  Yogesh Kumar, et al., bioRxiv - Genomics 2022

  Quote: ... 1% of nucleoside mix (Merck Millipore), 1000 U/ml recombinant leukemia inhibitory factor (LIF/ESGRO ...
• Slow integrin-dependent migration organizes networks of tissue-resident mast cells

  Sarah K. Bambach, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti- nidogen (1:300, Merck Millipore), anti-rat Alexa Fluor 405 (1:500 ...
• “Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models.”

  Irene Lara-Saez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CGRP (c8198, Merck, 1:2000); anti-Keratin 5 (PRB-160P ...
• Characterization of a new lacrimal gland cell line in 2D and 3D cell culture models

  Sophie Gleixner, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1 % T3/transferrin solution (#T8158, Merck), 0.1 % insulin solution (#I5500 ...
• Silybin A from Silybum marianum reprograms lipid metabolism to induce a cell fate-dependent class switch from triglycerides to phospholipids

  Solveigh C. Koeberle, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... [13C3]-Malonyl-CoA (1 nmol; Merck) was used as internal standard.
• Genomic and phenotypic stability of fusion-driven pediatric Ewing sarcoma cell lines

  Merve Kasan, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 1% penicillin-streptomycin (Merck, Germany). Each cell culture flask was monitored daily and cells were passaged twice per week using Trypsin-EDTA (0.25% ...
• Genomic location dictates lytic promoter activity during herpes simplex virus latency

  Navneet Singh, et al., bioRxiv - Microbiology 2023

  Quote: ... and 1 Protease inhibitor tablet (Merck) per 10 ml of water ...
• Aurora B controls microtubule stability to regulate abscission dynamics in stem cells

  Snježana Kodba, et al., bioRxiv - Cell Biology 2024

  Quote: ... 1 μM PD 0325901 (Merck #PZ0162), LIF (Merck # ESG1107) ...
• Extensive remodelling of XIST regulatory networks during primate evolution

  Emmanuel Cazottes, et al., bioRxiv - Genomics 2023

  Quote: ... and 1 µM IWR1-endo (Merck). RhiPSC24 were routinely passaged in clumps using Gentle Cell Dissociation reagent (Stemcell Technologies ...
• The interplay between miRNAs and chromatin regulators underpins premature differentiation within neurodevelopmental disorders (NDDs)

  Jamie S Wood, Mouhamed Alsaqati, Adrian J Harwood, bioRxiv - Neuroscience 2023

  Quote: ... H3K9me2 (1:500) (17-648, Merck), diluted in blocking solution ...
• The interplay between miRNAs and chromatin regulators underpins premature differentiation within neurodevelopmental disorders (NDDs)

  Jamie S Wood, Mouhamed Alsaqati, Adrian J Harwood, bioRxiv - Neuroscience 2023

  Quote: ... REST (1:100, 07-579, Merck). Secondary antibodies were as follows ...
• The eIF4A2 negative regulator of mRNA translation promotes extracellular matrix deposition to accelerate hepatocellular carcinoma initiation

  Madeleine Moore, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and ITGA5 (Merck AB1928, 1:1000). Fibronectin (abcam 2413 ...
• Implementation of pupylation-based proximity labelling in plant biology reveals regulatory factors in cellulose biosynthesis

  Shuai Zheng, et al., bioRxiv - Plant Biology 2024

  Quote: ... α-YFP (Venus) (Merck, MABE1906, 1:1000) and secondary antibodies α-mouse-HRP (Agilent ...
• JNK1 And Downstream Signalling Hubs Regulate Anxiety-Like Behaviours In A Zebrafish Larvae Phenotypic Screen

  Ye Hong, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... Bryostatin-1 and MK801 from MERCK Sigma Aldrich Solutions ...
• Characterisation and reprogramming of bacteriophage mv4 integrase recombination specificity

  Kevin Debatisse, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 1 µg polydIdC (Merck KGaA, Germany), 0.1 mg/ml BSA ...
• Programmed withdrawal of cilia maintenance followed by centriole capping leads to permanent cilia loss during cerebellar granule cell neurogenesis

  Sandii Constable, et al., bioRxiv - Cell Biology 2023

  Quote: ... Rootletin (1:500, Merck-Millipore #ABN1686), SOX9 (1:500 ...
• Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration

  Marco Leibinger, et al., bioRxiv - Neuroscience 2023

  Quote: ... and penicillin/streptomycin (1:50; Merck) and passed through a cell strainer (40 µm ...
• Lung inflammation is associated with lipid deposition

  Daria M Potashnikova, et al., bioRxiv - Pathology 2023

  Quote: ... with 1% β-mercaptoethanol (Merck, Germany). The volume of tissue suspension was adjusted to 1.5 mL with nuclease-free water ...
• Axon guidance during CNS regeneration is required for specific brain innervation

  Celine Delpech, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-RBPMS (Merck Millipore, 1:400), anti-VIP (Immunostar ...
• Inhibition of microtubule detyrosination by parthenolide facilitates functional CNS axon regeneration

  Marco Leibinger, et al., bioRxiv - Neuroscience 2023

  Quote: ... and penicillin/streptomycin (1:50; Merck) and passed through a cell strainer (40 µm ...
• Control of a gene transfer agent cluster in Caulobacter crescentus by transcriptional activation and anti-termination

  Ngat T. Tran, Tung B.K. Le, bioRxiv - Microbiology 2023

  Quote: ... 1 μL of Benzonase nuclease (Merck), and an EDTA-free protease inhibitor tablet (Merck) ...
• “Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models.”

  Irene Lara-Saez, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-CGRP (c8198, Merck, 1:2000); anti-Aquaporin 5 (ab78486 ...
• Dodecyl Creatine Ester Improves Cognitive Function and Identifies Drivers of Creatine Deficiency

  Aloïse Mabondzo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-PSD95 (1:2000, Merck, MABN68), anti-tubulin (1:2000 ...
• Unraveling the intricate microtubule inner protein networks that reinforce mammalian sperm flagella

  Miguel Ricardo Leung, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1% benzonase (Merck Millipore, Darmstadt, Germany), 1 mM sodium orthovanadate ...
• Long-term mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

  Marco Novais-Cruz, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-Mad1 (1:1,000; Merck), rabbit anti-Kif4a (1:1,000 ...
• Long-term mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

  Marco Novais-Cruz, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse anti-MPM2 (1:1,000, Merck), mouse anti-GAPDH (1:50,000 ...
• Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics

  Rahel Dabrowski, Susanna Tulli, Martin Graef, bioRxiv - Cell Biology 2022

  Quote: ... 1% (v/v) β-mercaptoethanol (Merck)).
• Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe

  Gaspard Kerner, et al., bioRxiv - Genetics 2022

  Quote: ... and 1 mM PMSF (#10837091001, Merck). Protein extracts and supernatants were resolved by electrophoresis in Criterion TGX 10% precast gels (Bio-Rad) ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Sox2 (1:150, Merck; Ab5603), anti-Iba1 (1:500 ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-NeuN (1:200, Merck; MAB377), anti-Ki67 (1:500 ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-Sox2 (1:70, Merck; Ab5603), anti-MAP2 (1:100 ...
• Zika virus-induces metabolic alterations in fetal neuronal progenitors that could influence in neurodevelopment during early pregnancy

  Javier Gilbert-Jaramillo, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-NeuN (1:150, Merck; MAB377) and ...
• Selective transduction and photoinhibition of pre-Botzinger neurons that project to the facial nucleus in rats affect the nasofacial activity

  MR Melo, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-TH (1:5000, Merck-Millipore ...
• SARM1 detection in oligodendrocytes but not Schwann cells though sarm1/Sarm1 deletion does not perturb CNS nor PNS myelination in zebrafish and mice

  Shaline V. Fazal, et al., bioRxiv - Neuroscience 2022

  Quote: ... Alexa Fluor 647 (Merck, 1:1000,15389818), DAPI (Thermo scientific ...
• Cross-β helical filaments of Tau and TMEM106B in Gray and White Matter of Multiple System Tauopathy with presenile Dementia

  Md Rejaul Hoq, et al., bioRxiv - Neuroscience 2023

  Quote: ... RD3 (Merck 05–803, 1:3,000), and RD4 (Upstate ...
• Imaging of plant calcium-sensor kinase conformation monitors real time calcium decoding in planta

  Anja Liese, et al., bioRxiv - Biochemistry 2023

  Quote: ... and 1 × protease inhibitor mixture (Merck)) and centrifuged at 20,000 x g for 10 min at 4 °C ...
• The temporal transcriptomic signature of cartilage formation

  Roland Á. Takács, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and stained with 1% AB (Merck) for 15 min in 3% acetic acid and 1% HCl (pH 1) ...
• A metabolite sensor subunit of the Atg1/ULK complex regulates selective autophagy

  A.S. Gross, et al., bioRxiv - Cell Biology 2022

  Quote: ... 1% (v/v) β-mercaptoethanol (Merck)).
• Functional synapses between small cell lung cancer and glutamatergic neurons

  Anna Schmitt, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and cystein (1 μg/ml, Merck), followed by mechanical trituration in medium supplemented with 10% fetal bovine serum (Gibco) ...