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401 - 450 of 1663 citations for 3 Acetyl 5 4 chlorophenyl 2 methylfuran since 2020

• PD-1 negatively regulates helper T cell differentiation into Th2

  Masaki Tajima, et al., bioRxiv - Immunology 2024

  Quote: ... Mouse IL-4 DuoSet ELISA (R&D Systems, catalog# DY404) and Mouse IL-13 DuoSet ELISA (R&D Systems ...
• Integrating central and peripheral neurons in elongating multi-lineage-organized gastruloids

  Zachary T. Olmsted, Janet L. Paluh, bioRxiv - Developmental Biology 2020

  Quote: ... 2 ng/ml HGF (R&D Systems) and 50 μM Y-27632 (Tocris Bioscience) ...
• A Quantitative Model of Cellular Decision Making in Direct Neuronal Reprogramming

  Adriaan Merlevede, et al., bioRxiv - Systems Biology 2020

  Quote: ... GDNF (2 ng/mL, R&D Systems), NT3 (10 ng/µL ...
• Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

  Endika Prieto-Fernández, et al., bioRxiv - Cell Biology 2021

  Quote: ... syndecan-2 (R&D Systems Cat#: FAB2965P), syndecan-3 (R&D Systems Cat# ...
• A Combined Human Gastruloid Model of Cardiogenesis and Neurogenesis

  Zachary T. Olmsted, Janet L. Paluh, bioRxiv - Developmental Biology 2022

  Quote: ... 2 ng/ml HGF (R&D Systems) and 50 μM Y-27632 (Tocris Bioscience) ...
• Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells

  Anne Marchalot, et al., bioRxiv - Immunology 2020

  Quote: ... 5ng/mL hIL-2 (R&D Systems) and 100ng/mL Mega-CD40 ligand (Enzo Life Sciences ...
• Age-related pathological impairments in induced neurons derived from patients with idiopathic Parkinson’s disease

  Janelle Drouin-Ouellet, et al., bioRxiv - Neuroscience 2021

  Quote: ... GDNF (2 ng/mL, R&D Systems), NT3 (10 ng/μL ...
• Protective heterologous T cell immunity in COVID-19 induced by MMR and Tdap vaccine antigens

  Vijayashree Mysore, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL15(2) (R&D systems, #MAB247) at 5µg/ml ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 2 ng/ml TGFB1 (R&D Systems) and 0.4 μM IWP2 (Selleck Chemicals) ...
• DDHD2 is necessary for activity-driven fatty acid fueling of nerve terminal function

  Mukesh Kumar, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2% N-21 (R&D Systems, AR008), and 4 μM cytosine β-D-arabinofuranoside (Millipore Sigma ...
• HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A

  Larissa Butler, et al., bioRxiv - Cell Biology 2022

  Quote: ... 20ng/ml FGF-2 (R&D systems), 5μM Y-27632 (Geron) ...
• Localized nanoparticle-mediated delivery of miR-29b normalises the dysregulation of bone homeostasis caused by osteosarcoma whilst simultaneously inhibiting tumour growth

  Fiona E. Freeman, et al., bioRxiv - Bioengineering 2022

  Quote: ... A BMP-2 ELISA (R&D systems) was used to quantify the levels of BMP-2 released by the hydrogels ...
• Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities

  Makrina Daniilidou, et al., bioRxiv - Neuroscience 2022

  Quote: ... ENPP-2 (DENP20, R&D Systems, Europe), TRX-1 (RAB1756 ...
• Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

  Kate Huang, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by IWP-2 (R&D Systems) for 48 hrs (day 1-3) ...
• Binucleated human hepatocytes arise through loss of membrane anchorage to the midbody during endomitosis

  Gabriella Darmasaputra, et al., bioRxiv - Cell Biology 2023

  Quote: ... type 2 (R&D Systems, #3533-001) and cultured and passaged as previously described for Chol-Orgs75 and Hep-Orgs44 ...
• A Bi-Specific T Cell-Engaging Antibody Shows Potent Activity, Specificity, and Tumor Microenvironment Remodeling in Experimental Syngeneic and Genetically Engineered Models of GBM

  Markella Zannikou, et al., bioRxiv - Immunology 2024

  Quote: ... supplemented with 2% FBS (R&D Systems) and TruStain FcX™ anti-mouse CD16/32 (1:200 ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... Sigma)/Laminin (2 µg/mL; R&D Systems)/Fibronectin (1 µg/mL ...
• Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells

  Farhat Parween, et al., bioRxiv - Immunology 2023

  Quote: ... CXCL9 (5 μg, MAB392), mouse IgG1 isotype control (5 μg, MAB002) and mouse IgG2B isotype control (MAB004) all from R&D Systems, at RT for 2 h ...
• Reprogramming human B cells with custom heavy chain antibodies

  Geoffrey L. Rogers, et al., bioRxiv - Immunology 2023

  Quote: ... cells were initially activated at 5 x 105 cells/mL in B cell activation media: 5 µg/mL soluble CD40L (R&D Systems), 10 µg/mL anti-His tag antibody (clone AD1.1.10 ...
• Penile cavernous sinusoids are Prox1-positive hybrid vessels

  Sarah Schnabellehner, et al., bioRxiv - Cell Biology 2023

  Quote: ... Mouse VEGFR3 domains 1-4 and 4-7 were detected by probing with the polyclonal goat anti-mouse VEGFR3 antibody (R&D Systems, AF743, 1:1000) against the extracellular domain of VEGFR3 ...
• Single-cell transcriptomics reveals the identity and regulators of human mast cell progenitors

  Chenyan Wu, et al., bioRxiv - Cell Biology 2021

  Quote: ... IL-5 (Peprotech and R&D Systems, Minneapolis, MN), erythropoietin (Janssen-Cilag Ab ...
• Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during periods of clinical latency

  Melanie Werner-Klein, et al., bioRxiv - Cancer Biology 2020

  Quote: ... 5 ng/ml GRO-α (R&D Systems, Germany), 20 ng/ml hyper interleukin-6 (kindly provided by S ...
• Gene network modeling via TopNet reveals robust epistatic interactions between functionally diverse tumor critical mediator genes

  Helene R. McMurray, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and 5 U/ml interferon γ (R&D Systems). All experiments testing the effects of genetic perturbations were carried out at the non-permissive temperature for large T function (39°C ...
• The Modular µSiM: a Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro

  Molly C. McCloskey, et al., bioRxiv - Bioengineering 2022

  Quote: ... and human fibronectin (5 µg/cm2, R&D Systems) for 1 hour at 37°C ...
• Combinatorial T cell engineering eliminates on-target off-tumor toxicity of CD229 CAR T cells while maintaining anti-tumor activity

  Erica R. Vander Mause, et al., bioRxiv - Bioengineering 2022

  Quote: ... 5 μg/ml recombinant human CD229 (R&D Systems) was immobilized on a black 96-well plate (Greiner Bio-One ...
• Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands

  Katrin Raute, et al., bioRxiv - Immunology 2022

  Quote: ... α-ULPB2/5/6 (clone 165903) from R&D Systems. α-CD103 (clone 2G5 ...
• A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

  Inseon Kim, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 µM Forskolin (F) (R&D Systems, 1099/50), 5 µM RepSox (R ...
• Bioengineering of a human innervated cardiac muscle model

  Lennart Valentin Schneider, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 ng/mL BMP4 (R&D systems, #314-BP), 1 μM CHIR99021 (Stemgent ...
• Monomeric amyloid-β inhibits microglial inflammatory activity in the brain via an APP/heterotrimeric G protein-mediated pathway

  Hyo Jun Kwon, Devi Santhosh, Zhen Huang, bioRxiv - Neuroscience 2023

  Quote: ... goat anti-MMP2 (R&D Systems; 5 μg/ml), rabbit anti-Calretinin (Chemicon ...
• Transient BRD4 degradation improves cardiac reprogramming by inhibiting macrophage/Oncostatin M induced JAK/STAT pathway

  Liu Liu, et al., bioRxiv - Cell Biology 2024

  Quote: ... recombinant human VEGF165 (5 ng/ml, R&D Systems), recombinant human FGF10 (25 ng/ml ...
• Generation of human-pig chimeric renal organoids using iPSC technology

  Koki Fujimori, et al., bioRxiv - Bioengineering 2024

  Quote: ... 5 ng/mL human Bmp4 (R&D Systems, Inc.), 3 μM CHIR99021 ...
• A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions

  Ryan J. Farrell, et al., bioRxiv - Cell Biology 2024

  Quote: ... and 5% Fetal Bovine Serum (R&D Systems S11550). Cells were transfected using Lipofectamine 3000 (Thermo Fisher L3000015 ...
• LncRNA Bigheart trans-activates gene expression in a feed forward mechanism that facilitates calcineurin-NFAT signaling in myocardial hypertrophy

  Nicolò Mangraviti, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 5 ng/ml Recombinant human BMP4 (R&D Systems), 9 ng/ml Recombinant Human/Mouse/rat Activin A (R&D Systems ...
• Recognition of highly branched N-glycans of the porcine whipworm by the immune system

  Barbara Eckmair, et al., bioRxiv - Biochemistry 2023

  Quote: ... 5 µg/ml human MGL-Fc (R&D System) and 1 µg/ml human Dectin-2-Fc (Sino Biological ...
• 14-3-3 binding motif phosphorylation disrupts Hdac4 organized condensates to stimulate cardiac reprogramming

  Liu Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... recombinant human VEGF165 (5 ng/ml, R&D Systems), recombinant human FGF10 (25 ng/ml ...
• A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

  Inseon Kim, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 µM RepSox (R) (R&D Systems, 3742/50) and 3 µM CHIR99021 (C ...
• A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

  Hyo Jun Kwon, Devi Santhosh, Zhen Huang, bioRxiv - Neuroscience 2024

  Quote: ... goat anti-MMP2 (R&D Systems; 5 μg/ml), rabbit anti-Calretinin (Chemicon ...
• Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity

  Sicong Zhang, Robert G. Roeder, bioRxiv - Molecular Biology 2024

  Quote: ... with 5 % fetal bovine serum (R&D systems, S11150). HEK 293T cells from ATCC were maintained in DMEM medium with 10% FBS ...
• Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

  Nevin K. Zacharia, et al., bioRxiv - Biochemistry 2024

  Quote: ... 5 μM ubiquitin (R&D Systems #U-100H-10M) and 2 μM His-TEV-HsIFT172C1 ...
• Fetal Liver-like Organoids Recapitulate Blood-Liver Niche Development and Multipotent Hematopoiesis from Human Pluripotent Stem Cells

  Milad Rezvani, et al., bioRxiv - Developmental Biology 2024

  Quote: ... we applied 5 ng/ml FGF2 (R&D Systems), 20 ng/ml EGF (R&D Systems) ...
• IL-1β-driven NF-κB transcription of ACE2 as a Mechanism of Macrophage Infection by SARS-CoV-2

  Cadence Lee, et al., bioRxiv - Immunology 2024

  Quote: ... human ACE2 (5 μg/mL; R&D Systems, MAB10823) with Donkey anti-Rabbit IgG (H+L ...
• Rigosertib Reverses Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome

  Levi Legler, et al., bioRxiv - Molecular Biology 2024

  Quote: ... and 5 ng/mL VEGF-A (R&D Systems) on Day 3 and stored at 37 °C in 5% CO2 ...
• Quantitative live-cell imaging of secretion activity reveals dynamic immune responses

  Mai Yamagishi, et al., bioRxiv - Biophysics 2022

  Quote: ... The medium was supplemented with 10 ng/ml recombinant mouse IL-2 (rmIL-2) (402-ML, R&D systems) for long-term culture of mouse ILC2s.
• TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8⁺ T cells

  Helen Carrasco Hope, et al., bioRxiv - Immunology 2022

  Quote: ... supernatants were collected and IL-2 concentration was determined using the Mouse DuoSet IL-2 ELISA (R&D Systems), following manufacturer’s instructions ...
• HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1

  Thomas Serrano, et al., bioRxiv - Cell Biology 2024

  Quote: ... the cells were diluted 1:10 in interleukin 2 (IL-2)-containing RPMI (100 IU/mL; R&D Systems) supplemented with 10 % FBS and penicillin–streptomycin (RPMI-IL-2 ...
• ART duration and immunometabolic state determine efficacy of DC-based treatment restoring functional HIV- specific CD8+ T cells in PLWH

  Marta Calvet-Mirabent, et al., bioRxiv - Immunology 2022

  Quote: ... or 1 μg/ml goat IgG anti-human TIM-3 (R&D systems) and alone or in combination of 5 mM Metformin (SIGMA) ...
• Subcellular mapping of the protein landscape of SARS-CoV-2 infected cells for target-centric drug repurposing

  Jayasankar Mohanakrishnan Kaimal, et al., bioRxiv - Cell Biology 2022

  Quote: ... commercial Sigma-1 R antibody to 3 µg/ml (MAB1076, R&D systems) chicken Calreticulin (Abcam ...
• A Genome-engineered Bioartificial Implant for Autoregulated Anti-Cytokine Drug Delivery

  Yun-Rak Choi, et al., bioRxiv - Synthetic Biology 2020

  Quote: ... 10 ng/mL transforming growth factor beta 3 (TGF-β3, R&D Systems) and 100nM dexamethasone12,27 to make implantable cartilage constructs11 ...
• IFN-λ is protective against lethal oral Toxoplasma gondii infection

  Mateo Murillo-León, et al., bioRxiv - Immunology 2023

  Quote: IFN-λ2/3 concentration was determined by commercial sandwich ELISA (R&D Systems) from supernatants infected or not with T ...
• OrBITS: Label-free and time-lapse monitoring of patient derived organoids for advanced drug screening

  Christophe Deben, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 3-day old organoids were harvested with Cultrex Harvesting Solution (R&D Systems) and frozen in Recovery Cell Culture Freezing Medium (GIBCO) ...