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2801 - 2850 of 10000+ citations for 4 Nitrophenyl beta D glucuronic acid sodium salt since 2020

• Loss of Progranulin Results in Increased Pan-Cathepsin Activity and Reduced LAMP1 Lysosomal Protein

  Abigail Anderson, Malú G. Tansey, bioRxiv - Cell Biology 2023

  Quote: ... with 10% HI-FBS (R&D Systems S11150), 100x Pen/Strep (Gibco 15140-122) ...
• Pancreatic islet cell stress induced by insulin-degrading enzyme deficiency promotes islet regeneration and protection from autoimmune diabetes

  Shuaishuai Zhu, et al., bioRxiv - Cell Biology 2023

  Quote: Recombinant mouse REG2 (2098-RG, R&D Systems) and human insulin (11376497 ...
• Connexin 43 and Cell Culture Substrate Differentially Regulate OCY454 Osteocytic Differentiation and Signaling to Primary Bone Cells

  Gabriel A. Hoppock, et al., bioRxiv - Cancer Biology 2023

  Quote: ... supplied standards and controls ELISA (R&D Systems; DuoSet Ancillary Kit #2 Catalog #DY008) ...
• Selective Inhibition of Interleukin-2 Inducible T Cell Kinase (ITK) Enhances Anti-Tumor Immunity in Association with Th1-skewing, Cytotoxic T cell Activation, and Reduced T Cell Exhaustion

  Lih-Yun Hsu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... IL-5 (10 ng/ml, R&D Systems), anti-human IFNγ (B27 ...
• Hypoxia regulate developmental coronary angiogenesis potentially through VEGFR2- and SOX17-mediated signaling

  Halie E. Vitali, et al., bioRxiv - Developmental Biology 2023

  Quote: ... VEGFR2 (1:100 Cat: AF644, R&D Systems), VE-Cadherin (1:125 ...
• Preclinical assessment of CAR-NK cell-mediated killing efficacy and pharmacokinetics in a rapid zebrafish xenograft model of metastatic breast cancer

  Nivedha Murali Shankar, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or ErBb2-Fc fusion proteins (R&D Systems) for 30 min on ice ...
• Targeting the glucose-insulin link in head and neck squamous cell carcinoma induces cytotoxic oxidative stress and inhibits cancer growth

  Simbarashe Mazambani, et al., bioRxiv - Cancer Biology 2023

  Quote: ... p63 (1:100; R&D Systems AF-1916), GLUT1 (1:250 ...
• Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling

  Alex S Choi, et al., bioRxiv - Biochemistry 2023

  Quote: ... and Wnt3a were purchased from R&D Systems. A83-01 (catalog 100-1041 ...
• Patterning and folding of intestinal villi by active mesenchymal dewetting

  Tyler R. Huycke, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 500ng/ml R-Spondin1 (R&D Systems)) to induce HIO formation ...
• Propagation of neuronal micronuclei regulates microglial states

  Sarasa Yano, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-CD206 (AF2535, R&D systems, 1:200), anti-P2ry12 (AS-55043A ...
• A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury

  Aleksandra Boikova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 9 ng/ml Activin A (R&D Systems), 5 ng/ml FGF-2 (R&D Systems ...
• A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury

  Aleksandra Boikova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 5 ng/ml FGF-2 (R&D Systems) and 1 μM CHIR99021 (STEMCELL Technologies) ...
• Generating human neural diversity with a multiplexed morphogen screen in organoids

  Neal D. Amin, et al., bioRxiv - Neuroscience 2023

  Quote: Molecules used: EGF (R&D Systems, 236-EG), FGF2 (R&D Systems ...
• Cyclophosphamide induces the loss of taste bud innervation in mice

  Ryan M. Wood, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Car4 (1: 1000; R&D Systems AF2414), or with Troma (1:1000 ...
• Neuronal DAMPs exacerbate neurodegeneration via astrocytic RIPK3 signaling

  Nydia P. Chang, et al., bioRxiv - Neuroscience 2023

  Quote: ... Recombinant HMGB1 (R&D Systems, 1690-HMB-050) and S100B (Human ...
• Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin

  Marvin Reich, et al., bioRxiv - Neuroscience 2023

  Quote: ... or anti-mPGRN antibody (R&D Systems, BAF2557) at 0.2 µg/mL as capture antibody and for detection rabbit anti-hPGRN (Thermo Fisher Scientific ...
• Orthogonal analysis of mitochondrial function in Parkinson’s disease patients

  Sander Barnhoorn, et al., bioRxiv - Neuroscience 2023

  Quote: ... 40 ng/ml IGF-1 (R&D Systems) and 50 ug/ml Ascorbic Acid (Merck ...
• Orthogonal analysis of mitochondrial function in Parkinson’s disease patients

  Sander Barnhoorn, et al., bioRxiv - Neuroscience 2023

  Quote: ... 10 ng/ml Interleukin-6 (R&D Systems), 40 ng/ml IGF-1 (R&D Systems ...
• Orthogonal analysis of mitochondrial function in Parkinson’s disease patients

  Sander Barnhoorn, et al., bioRxiv - Neuroscience 2023

  Quote: ... 10 ng/ml Interleukin-3 (R&D Systems), 10 ng/ml Interleukin-6 (R&D Systems) ...
• Distinct Functional States of Neutrophils by Actin Disassembly and NF-kB/STAT3 Signaling

  Niko Heineken, et al., bioRxiv - Immunology 2023

  Quote: ... IL-10 (200 U/ml, R&D systems), fMLP (100 µM ...
• Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia

  Changsheng Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 20 ng/ml BMP4 (R&D Systems). On day 2 ...
• Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice

  Allen L. Pan, et al., bioRxiv - Neuroscience 2023

  Quote: ... All cytokines were purchased from R&D Systems.
• Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting

  Jingyi Wei, et al., bioRxiv - Bioengineering 2023

  Quote: ... and plated into Cultrex (R&D Systems 343400502)-coated 96-well plates with mTESR media containing ROCK inhibitor Y-27632 (10 uM ...
• Rational screening for cooperativity in small-molecule inducers of protein–protein associations

  Shuang Liu, et al., bioRxiv - Biophysics 2023

  Quote: ... BirA (R&D systems 10464-BA, 90 μL) and HRV 3C protease (Pierce 88946 ...
• WFIKKN2 is a bifunctional axon guidance cue that signals through divergent DCC family receptors

  Kelsey R. Nickerson, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Recombinant mWFIKKN2 (Biotechne/R&D Systems, 2070-GS) was applied (at indicated concentrations ...
• Patient iPSC models reveal glia-intrinsic phenotypes in multiple sclerosis

  Benjamin L.L. Clayton, et al., bioRxiv - Neuroscience 2023

  Quote: ... GDNF (40ng/mL; R&D Systems 212-GD), Laminin (1μg/mL) ...
• ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway

  Songnan Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and 10% heat-inactivated FBS (R&D Systems) containing IMDM (ThermoFisher ...
• Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion

  Ryan H. Purcell, et al., bioRxiv - Genomics 2023

  Quote: ... and NT-3 (20ng/ml, R&D Systems) every two days ...
• A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia

  Lalit Kaurani, et al., bioRxiv - Neuroscience 2023

  Quote: ... and 20 ng/ml SCF (R&D Systems). Four-day EBs were then differentiated in 6-well plates (15 EBs/well ...
• Immunoglobulin M regulates airway hyperresponsiveness independent of T helper 2 allergic inflammation

  Sabelo Hadebe, et al., bioRxiv - Immunology 2023

  Quote: ... and IL-13 (R&D Systems, Minneapolis, Minn), were measured using ELISA assays according to the manufacturer’s protocol.
• Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI

  Alexander Kapustin, et al., bioRxiv - Cell Biology 2023

  Quote: ... gelatin-3BP/MAC-2BP (R&D systems, AF2226), EDIL3 antibody (R&D systems ...
• Perivascular and peribronchiolar granuloma-associated lymphoid tissue and B-cell gene expression pathways identify asymptomatic Mycobacterium tuberculosis lung infection in Diversity Outbred mice

  Deniz Koyuncu, et al., bioRxiv - Pathology 2023

  Quote: ... developed with TMB (ThermoFisher or R&D Systems), stopped using 0.25M HCl ...
• Human inborn errors of long-chain fatty acid oxidation show impaired inflammatory responses to TLR4-ligand LPS

  Signe Mosegaard, et al., bioRxiv - Immunology 2023

  Quote: ... and CXCL10 (R&D Systems Cat. No. DY266), all according to the manufacturer’s instructions ...
• Altered DNA methylation underlies monocyte dysregulation and innate exhaustion memory in sepsis

  Blake A. Caldwell, Yajun Wu, Jing Wang, Liwu Li, bioRxiv - Immunology 2023

  Quote: ... MARCO (Alexa Fluor 647; R&D Systems #FAB29561R), FAS (BV605 ...
• Altered DNA methylation underlies monocyte dysregulation and innate exhaustion memory in sepsis

  Blake A. Caldwell, Yajun Wu, Jing Wang, Liwu Li, bioRxiv - Immunology 2023

  Quote: ... CXCR2 (Alexa Fluor 488; R&D Systems # FAB2164G), CD68 (APC-Fire750 ...
• CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan

  Linda Heilig, et al., bioRxiv - Microbiology 2023

  Quote: ... granzyme B (R&D Systems, Minneapolis, MN, USA), and perforin (abcam ...
• SR-BI regulates the synergistic mast cell response by modulating the plasma membrane-associated cholesterol pool

  Sandro Capellmann, et al., bioRxiv - Immunology 2023

  Quote: ... and TNF (R&D Systems, #410-MT-010) serial 1:2 standard dilutions were added and plates were incubated overnight at 4°C ...
• Distinct Functional States of Neutrophils by Actin Disassembly and NF-kB/STAT3 Signaling

  Niko Heineken, et al., bioRxiv - Immunology 2023

  Quote: ... GM-CSF (100 U/µl, R&D systems), BAY11-7082 (2.5 µM ...
• Distinct Functional States of Neutrophils by Actin Disassembly and NF-kB/STAT3 Signaling

  Niko Heineken, et al., bioRxiv - Immunology 2023

  Quote: ... IL-10 (200 U/ml, R&D systems), GM-CSF (1000 U/µl ...
• Phosphoproteomic profiling highlights CDC42 and CDK2 as key players in the regulation of the TGF-β pathway in ALMS1 and BBS1 knockout models

  Brais Bea-Mascato, et al., bioRxiv - Cell Biology 2023

  Quote: ... rhTGF-β1 ligand (R&D Systems; 240-B) was added to the plates at a final well concentration of 2ng/mL for 0 and 30 min ...
• Epitope Engineered Human Haematopoietic Stem Cells are Shielded from CD123-targeted Immunotherapy

  Romina Marone, et al., bioRxiv - Bioengineering 2023

  Quote: ... and IL-15 (5ng/ml; R&D systems). Electroporation was performed with the 4D-Nucleofector™ system (Lonza ...
• Loss of G9a does not phenocopy the requirement for Prdm12 in the development of the nociceptive neuron lineage

  Panagiotis Tsimpos, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Goat polyclonal α-Ret (R&D Systems, AF482), Rabbit polyclonal α-CGRP (Sigma-Aldrich ...
• Time- and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification

  Yale S. Michaels, et al., bioRxiv - Immunology 2023

  Quote: ... SCF (50ng/mL, R&D Systems, 255-SC), IL-3 (10ng/mL ...
• Time- and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification

  Yale S. Michaels, et al., bioRxiv - Immunology 2023

  Quote: ... TPO (30ng/mL, R&D Systems, 288-TPN), IGF-I (25ng/mL ...
• Tuft cell-derived acetylcholine is an effector of type 2 immunity and directly targets helminth parasites in the gut lumen

  Marième Ndjim, et al., bioRxiv - Immunology 2023

  Quote: ... Noggin (100 ng ml−1) (R&D system) and R-Spondin (500 ng ml−1 ...
• Spatial enhancer activation determines inhibitory neuron identity

  Elena Dvoretskova, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-PROX1 (R&D Systems, AF2727, 1:250), anti-CTIP2 (Abcam ...
• S100A8-enriched microglia populate the brain of tau-seeded and accelerated aging mice

  Roxane Gruel, et al., bioRxiv - Neuroscience 2023

  Quote: ... SOX10 (1:500, goat, AF2864, R&D systems), Ionized calcium Binding Adaptor molecule 1 (IBA1 ...
• Hypoxia-induced Complement Component 3 Promotes Aggressive Tumor Growth in the Glioblastoma Microenvironment

  Rebecca Rosberg, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Olig2 (R&D Systems, AF2418, 1:200 dilution) as a tumor marker ...
• Identification of a Musashi2 translocation as a novel oncogene in myeloid leukemia

  Kyle Spinler, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and TPO (20 ng/ml, R&D Systems). Cells were retrovirally infected with MSCV-BCR-ABL-IRES-NGFR and MSCV-NUP98-HOXA9-IRES-huCD2 to generate bcCML ...
• Astrocytes in the retinorecipient superior colliculus display unique cellular and structural properties

  Josien Visser, et al., bioRxiv - Neuroscience 2022

  Quote: ... Sox9 (goat, 1:500, AF3075, R&D systems) and NeuN (mouse ...