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151 - 200 of 1327 citations for 3 2 Methylphenyl 4' trifluoromethylpropiophenone since 2020

• Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice

  Anna Zawistowska-Deniziak, et al., bioRxiv - Immunology 2022

  Quote: ... and rIL-4 (0.86ng/ml, R&D Systems) for 5-6 days ...
• Partial agonism improves the anti-hyperglycaemic efficacy of an oxyntomodulin-derived GLP-1R/GCGR co-agonist

  Phil Pickford, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... 10 mU recombinant DPP-4 (R&D Systems), or no enzyme as a control for non-enzymatic degradation over the same time period ...
• Functional imaging of conduction dynamics in cortical and spinal axons

  Milos Radivojevic, Anna Rostedt Punga, bioRxiv - Neuroscience 2023

  Quote: ... 1.4 nM neurotrophin 4 (NT4, R&D systems) and 1.3 nM human insulin-like growth factor 1 (hIGF-1 ...
• Remodeling of Il4-Il13-Il5 locus underlies selective gene expression

  Hiroyuki Nagashima, et al., bioRxiv - Immunology 2022

  Quote: ... IL-4 (50 ng/ml, R&D Systems) and anti-IFN-γ (10 μg/ml ...
• Metabolic sensor AMPK licenses CD103⁺ dendritic cells to induce Treg responses

  Thiago A Patente, et al., bioRxiv - Immunology 2023

  Quote: ... rIL-4 (0.86 ng/mL, R&D system) and rGM-CSF (10 ng/mL ...
• FMRP phosphorylation modulates neuronal translation through YTHDF1

  Zhongyu Zou, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 4 ng/ml WNT-3A (R&D Systems), 1 μM CHIR99021 M SB-431542 (Tocris) ...
• The extracellular matrix differentially directs myoblast motility in distinct forms of muscular dystrophy

  Ashlee M. Long, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-Thrombospondin-4 (cat# AF2390; R&D Systems), and anti-TIMP-1 (cat# AF980 ...
• Red cabbage juice-mediated gut microbiota modulation improves intestinal epithelial homeostasis and ameliorates colitis

  Emily Jean Wilson, et al., bioRxiv - Pathology 2023

  Quote: ... Anti-4-Hydroxynonenal (R&D Systems; Biotechne, MAB3249); Anti-MUC2 (Abcam ...
• The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix

  Joseph G. O’Brien, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Thrombospondin-4 (cat# AF2390; R&D Systems), anti-TGF-β3 (cat# ab15537 ...
• The effect of UVA light/8-methoxypsoralen exposure used in Extracorporeal Photopheresis treatment on platelets and extracellular vesicles

  Hayley Macleod, et al., bioRxiv - Cell Biology 2023

  Quote: ... and platelet factor 4 (PF4, R&D Systems) were performed according to the manufacturer’s instructions ...
• Monitoring macrophage polarization with gene expression reporters and bioluminescence phasor analysis

  Giulia Tedeschi, et al., bioRxiv - Bioengineering 2024

  Quote: ... IL-4 (20 ng/mL, R&D Systems) and IL-13 (20 ng/mL ...
• Physiological role and mechanisms of action for a long noncoding haplotype region

  Hong Xue, et al., bioRxiv - Genetics 2024

  Quote: ... OCT-4 (1:200, AF1759, R&D Systems), NANOG (1:200,ab80892 ...
• T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome

  Cansu Cimen Bozkus, et al., bioRxiv - Immunology 2024

  Quote: ... IL-4 (R&D Systems, 500 IU/mL) and Flt3L (R&D Systems ...
• IL-21 Shapes the B Cell Response in a Context-Dependent Manner

  Youngjun Kim, et al., bioRxiv - Immunology 2024

  Quote: ... IL-4 (R&D Systems, 12.5 ng/mL), IL-21 (R&D Systems ...
• Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

  Peiyuan Chai, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Siglec-4 Fc chimera protein (R&D Systems), Siglec-5 Fc chimera protein (R&D Systems) ...
• NECTIN-4 PET FOR OPTIMIZING ENFORTUMAB VEDOTIN DOSE-RESPONSE IN UROTHELIAL CARCINOMA

  Akhilesh Mishra, et al., bioRxiv - Cancer Biology 2024

  Quote: ... and mouse Nectin-4 proteins (R&D systems, catalog # 3116-N4-050 ...
• The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes

  Jiayi E. Wang, et al., bioRxiv - Immunology 2024

  Quote: ... 10 ng/mL IL-4 (R&D Systems) for M2 polarization ...
• The neural cell adhesion molecule NrCAM regulates development of hypothalamic tanycytes

  Alex Moore, et al., bioRxiv - Neuroscience 2021

  Quote: ... supplemented with 3 nM Shh (1845-SH; R&D Systems), as used in Ohyama et al (2005 ...
• Activator protein-1 transactivation of the major immediate early locus is a determinant of cytomegalovirus reactivation from latency

  Benjamin A. Krishna, et al., bioRxiv - Microbiology 2020

  Quote: ... GM-CSF and IL-3 [all from R&D Systems]) ...
• Mast cell regranulation involves a metabolic switch promoted by the interaction between mTORC1 and a glucose-6-phosphate transporter

  Jason A Iskarpatyoti, et al., bioRxiv - Cell Biology 2021

  Quote: ... 5 ng/mL recombinant murine IL-3 (R&D Systems, and 5% stem cell factor-containing supernatant from CHO-KL cells for 4-6 weeks until maturation ...
• Nutrient metabolism regulates insulin granule formation in the pancreatic islet β-cell via ER redox homeostasis

  Kristen E. Rohli, et al., bioRxiv - Cell Biology 2021

  Quote: ... cleaved Caspase 3 (rabbit, R&D systems MAB835, 1:500), CPE (rabbit ...
• DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells

  Yale S. Michaels, et al., bioRxiv - Bioengineering 2021

  Quote: ... and 3 U/mL EPO (R&D Systems 287-TC). Cells were cultured for 7 days followed EHT and assessed using by flow cytometry.
• Mechanisms Underlying WNT-mediated Priming of Human Embryonic Stem Cells

  Anna Yoney, et al., bioRxiv - Developmental Biology 2022

  Quote: ... we used a SMAD2/3 antibody (R&D systems, AF3797) in 2X10^6 hESCs that were treated with Activin for 2 h or 24 h with or without Wnt priming ...
• Phosphatidylserine within the Viral Membrane Enhances Chikungunya Virus Infectivity in a Cell-type Dependent Manner

  Kerri L. Miazgowicz, et al., bioRxiv - Microbiology 2022

  Quote: ... and anti-Tyro-3 (1:1000, R&D Systems, MAB859100) antibodies ...
• Sodium channel Nav1.2-L1342P variant displaying complex biophysical properties renders hyperexcitability of cortical neurons derived from human iPSCs

  Zhefu Que, et al., bioRxiv - Physiology 2021

  Quote: ... phrixotoxin-3 (PTx3) (R&D Systems, Cat # 4914. 15 μM); phenytoin (Sigma-Aldrich ...
• Vegfr3-tdTomato, a reporter mouse for microscopic visualization of lymphatic vessel by multiple modalities

  Esther Redder, et al., bioRxiv - Cell Biology 2021

  Quote: ... goat polyclonal anti-mouse VEGFR-3 (R&D Systems, AF743) and rabbit polyclonal anti-RFP (Rockland ...
• CD98 is critical for a conserved inflammatory response to diverse injury stimuli relevant to IPF exacerbations and COVID pneumonitis

  Panayiota Stylianou, et al., bioRxiv - Cell Biology 2022

  Quote: ... Mouse Galectin-3 DuoSet (all from R&D Systems,UK).
• Evaluation of Blood-Based Exosomes as Biomarkers for Aging-Related TDP-43 pathology

  Charisse N. Winston, et al., bioRxiv - Neuroscience 2022

  Quote: ... washed 3× in 1× wash buffer (895003, R&D Systems), blocked in 1% BSA for 1 hour at room temperature (RT) ...
• Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes

  Rahul Atmaramani, et al., bioRxiv - Neuroscience 2024

  Quote: ... Neurotrophin-3 (1ug/ml, 267-N3-025, R&D Systems), and Doxycycline Hydrochloride (1ug/ml ...
• Deep Learning Analysis on Images of iPSC-derived Motor Neurons Carrying fALS-genetics Reveals Disease-Relevant Phenotypes

  Rahul Atmaramani, et al., bioRxiv - Neuroscience 2024

  Quote: ... Neurotrophin-3 (1ug/ml, 267-N3-025, R&D Systems), EdU (5-ethynyl-2’-deoxyuridine ...
• The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis

  Julia A Alvarez, et al., bioRxiv - Microbiology 2024

  Quote: Recombinant Gal-3 (R&D Systems, Cat# 1197-GA-050) was pre-diluted in phosphate-buffered saline (PBS ...
• Accelerated Hematopoietic Stem Cell Aging in Space

  Jessica Pham, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Thrombopoietin (Tpo) and FLT-3 (all from R&D Systems)36 ...
• GATA1 knockout in human pluripotent stem cells generates enhanced neutrophils to investigate extracellular trap formation

  Thomas C. Harper, et al., bioRxiv - Immunology 2023

  Quote: ... 30 ng/ml IL-3 (R&D Systems, 203-IL), 30 ng/ml TPO (PeproTech ...
• COUP-TFII regulates early bipotential gonad signaling and commitment to ovarian progenitors

  Lucas G. A. Ferreira, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 3 days with 200 ng/mL FGF9 (R&D Systems), 1 μg/mL heparin (Sigma-Aldrich) ...
• A self-renewing biomimetic skeletal muscle construct engineered using induced myogenic progenitor cells

  Inseon Kim, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 3 µM CHIR99021 (C) (R&D Systems, 4423/50).
• Group comparison based on genetic information reveals lineage-specific therapeutic vulnerabilities in acute myeloid leukemia

  Jakushin Nakahara, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 10 ng/ml rhIL-3 (#203-IL, R&D Systems) and 10 ng/ml rhIL-6 (#206-IL ...
• Time- and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification

  Yale S. Michaels, et al., bioRxiv - Immunology 2023

  Quote: ... IL-3 (5.3 ng/ml; R&D Systems, 203-IL), CXCL12 (9.7 ng/ml ...
• Time- and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification

  Yale S. Michaels, et al., bioRxiv - Immunology 2023

  Quote: ... IL-3 (0.97 ng/ml; R&D Systems, 203-IL), CXCL12 (97.39 ng/ml) ...
• Primary human lung fibroblasts exhibit trigger- but not disease-specific cellular senescence and impair alveolar epithelial cell progenitor function

  Nora Bramey, et al., bioRxiv - Cell Biology 2023

  Quote: ... and human total MMP-3 (R&D Systems, cat.# DY513) according to manufacturer’s instructions ...
• Combined in vitro differentiation and cell sorting-based isolation of highly pure mouse bone marrow-derived basophils

  Adriana Rosa Gambardella, et al., bioRxiv - Cell Biology 2024

  Quote: Recombinant mouse (rm)IL-3 (#403-ML, R&D System)
• Activity-dependent extracellular proteolytic cascade remodels ECM to promote structural plasticity

  Jeet Bahadur Singh, et al., bioRxiv - Neuroscience 2024

  Quote: ... rhTIMP-3 (R&D Systems, Minneapolis / USA, Cat# 973-TM), was dissolved in distilled water at a concentration of 5 µM and stored at −20°C in small amounts ...
• Oncogene inactivation-induced senescence facilitates tumor relapse

  Philipp Schmitt, et al., bioRxiv - Cancer Biology 2024

  Quote: ... polyclonal anti-caspase-3 (1:1000; R&D Systems GmbH), polyclonal anti-LC3 (1:1000 ...
• Human CD4⁺/CD8α⁺ regulatory T cells induced by Faecalibacterium prausnitzii protect against intestinal inflammation

  Sothea Touch, et al., bioRxiv - Immunology 2022

  Quote: ... Lcn-2 levels were measured using Duoset murine Lcn-2 ELISA Kit (R&D systems) according to the manufacturer’s instructions and results were expressed as pg/g of colon content.
• Nef dimerization defect abrogates HIV viremia and associated immune dysregulation in the Bone Marrow-Liver-Thymus-Spleen (BLTS) humanized mouse model

  Shivkumar Biradar, et al., bioRxiv - Immunology 2021

  Quote: ... Sanofi-aventis Cat# NAC2004–5843-01) and interleukin-4 (IL-4; 1000 IU/mL; R&D Systems Cat# 204-1 L). Mature ...
• Pseudoirreversible inhibition elicits persistent efficacy of a sphigosine-1-phosphate receptor-1 antagonist

  Yuya Maruyama, et al., bioRxiv - Pharmacology and Toxicology 2024

  Quote: ... and the amount of interleukin (IL)-4 protein was evaluated using a Mouse IL-4 Quantikine ELISA Kit (R&D Systems). Change in body weight was calculated by the difference between the day of intrarectal oxazolone administration and the end of study.
• Regulation of layered T cell tolerance mechanisms by the NR4A family is essential to preserve immune homeostasis and suppress autoimmunity

  Ryosuke Hiwa, et al., bioRxiv - Immunology 2021

  Quote: ... Mouse IL-2 DuoSet ELISA DuoSet and Ancillary Reagent Kit 2 were from R&D Systems.
• Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks

  Oju Jeon, et al., bioRxiv - Bioengineering 2024

  Quote: ... 1 % P/S and 10 ng/ml fibroblast growth factor-2 (FGF-2, R&D Systems). Passage 3 hMSCs were used in this study.
• Blocking IL-10 signaling with soluble IL-10 receptor restores specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum

  Catiule de Oliveira Santos, et al., bioRxiv - Immunology 2020

  Quote: ... 1.25% of supernatant from Con-A-stimulated rat splenocytes (assay positive control), c) recombinant canine IL-4 (rcaIL-4, 360 ng/mL) (R&D Systems), d ...
• Antibodies to ILT3 abrogate myeloid immunosuppression and enable tumor killing

  Philip E. Brandish, et al., bioRxiv - Cancer Biology 2021

  Quote: ... supplemented with GM-CSF (1000 U/mL) and IL-4 (1000 U/mL) or GM-CSF & IL-4 (20 and 40 ng/mL, R&D Systems) and seeded into 24-well low binding plates at 1 × 106 cells/well ...
• Hydrophobicity drives receptor-mediated uptake of heat-processed proteins by THP-1 macrophages and dendritic cells, but not cytokine responses

  Ying Deng, et al., bioRxiv - Immunology 2020

  Quote: ... the plate was washed 3 times and incubated with 80 µL per well of monoclonal mouse IgG2B human sRAGE or galectin-3 antibody (R&D Systems, Minneapolis, Minnesota, United States) at a concentration of 0.2 µg/ml for 30 minutes shaking at room temperature ...