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1601 - 1650 of 10000+ citations for R + SCH 23390 hydrochloride since 2020

• Intermediate filament dysregulation and astrocytopathy in the human disease model of KLHL16 mutation in giant axonal neuropathy (GAN)

  Rachel Battaglia, et al., bioRxiv - Cell Biology 2023

  Quote: ... and EGF (20ng/mL, R&D Systems). Media was changed daily for days 7-16 and every other day for days 17-25 ...
• Histone demethylase KDM2A is a selective vulnerability of cancers relying on alternative telomere maintenance

  Fei Li, et al., bioRxiv - Cancer Biology 2023

  Quote: ... 53BP1 (1:300, AF1877; R&D Systems), BLM (1:250 ...
• ERBB-activated myofibroblastic cancer-associated fibroblasts promote local metastasis of pancreatic cancer

  Gianluca Mucciolo, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Phospho-RTK assays (ARY014; R&D Systems) were performed using 300 μg protein and following the Manufacturer’s instructions.
• McLTP1, a lipid transfer protein isolated from noni seeds induces effective healing of superficial burns

  Bianca Moreira Kurita, et al., bioRxiv - Immunology 2023

  Quote: ... Color reagent o-phenylenediamine (R&D Systems) was added and plates were incubated in the absence of light ...
• Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

  Kate Huang, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by IWP-2 (R&D Systems) for 48 hrs (day 1-3) ...
• Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

  Jie Wang, Amir Rattner, Jeremy Nathans, bioRxiv - Immunology 2023

  Quote: ... goat anti-S100A8 (R&D Systems AF3059); rabbit anti-ERG (Cell Signaling Technologies 97249) ...
• Caudal Fgfr1 disruption produces localised spinal mis-patterning and a terminal myelocystocele-like phenotype in mice

  Eirini Maniou, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-FoxA2 (AF2400, R&D Systems). Sections were washed ...
• An EOMES induced epigenetic deflection initiates lineage commitment at mammalian gastrulation

  Chiara M. Schröder, et al., bioRxiv - Developmental Biology 2023

  Quote: ... α-Brachyury (AF2085, R&D Systems, 1:1,000), α-Brg1 (SMARCA4 ...
• Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendroglia

  Raquel Garza, et al., bioRxiv - Neuroscience 2023

  Quote: ... OLIG2 (R&D Systems, AF2418, 1:500), OLIG2 (Sigma-Aldrich ...
• Golgi organization is a determinant of stem cell function in the small intestine

  Sandra Scharaw, et al., bioRxiv - Cell Biology 2023

  Quote: ... except for mouse Egf (R&D Systems) added at 200 ng/ml ...
• Spatial expression of an mRNA encoding Tie2-agonist in the capillary endothelium of the lung prevents pulmonary vascular leakage

  Katrin Radloff, et al., bioRxiv - Molecular Biology 2022

  Quote: ... pY992 Tie2 (R&D Systems, cat. #AF2720), Akt (CST ...
• Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury

  E. Malagola, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Rspo1 (R&D Systems, 3474-RS-050) supplemented with CHIR (Sigma-Aldrich ...
• PROX1 inhibits PDGF-B expression to prevent myxomatous degeneration of heart valves

  Yen-Chun Ho, et al., bioRxiv - Developmental Biology 2023

  Quote: ... PROX1 (R&D systems; AF2727; 1:200), and DPEAAE (cleaved-versican ...
• PROX1 inhibits PDGF-B expression to prevent myxomatous degeneration of heart valves

  Yen-Chun Ho, et al., bioRxiv - Developmental Biology 2023

  Quote: ... PROX1 (R&D systems; AF2727; 1:200), PROX1 (AngioBio ...
• Fluctuation of lysosomal protein degradation in neural stem cells of postnatal mouse brain

  He Zhang, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Sox2 (R&D Systems, AF2018), chicken anti-Nestin (aves ...
• Distinct Th17 effector cytokines differentially promote microglial and blood-brain barrier inflammatory responses during post-infectious encephalitis

  Charlotte R. Wayne, et al., bioRxiv - Neuroscience 2023

  Quote: ... and TNF (R&D Systems, 410-MT), which were added at 10ng/mL ...
• Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons

  Kenyi Saito-Diaz, et al., bioRxiv - Neuroscience 2023

  Quote: ... 1614)+300 nM CHIR99021 (R&D Systems, 4423). On day two ...
• Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons

  Kenyi Saito-Diaz, et al., bioRxiv - Neuroscience 2023

  Quote: ... 314-BP)+10 μM SB431542 (R&D Systems, 1614)+300 nM CHIR99021 (R&D Systems ...
• Mammalian Esophageal Stratified Tissue Homeostasis is Maintained Distinctively by the Epithelial Pluripotent p63+Sox2+ and p63-Sox2+ Cell Populations

  Xiaohong Yu, et al., bioRxiv - Cell Biology 2023

  Quote: ... 500 nM A83-01 (R&D Systems), 10 nM SB202190 (R&D Systems) ...
• A cis-regulatory element regulates ERAP2 expression through autoimmune disease risk SNPs

  Wouter J. Venema, et al., bioRxiv - Genomics 2023

  Quote: ... and anti-ERAP2 (AF3830, R&D Systems). Beads were washed in assay buffer (50 mM Tris ...
• EHD2 overexpression promotes tumorigenesis and metastasis in triple-negative breast cancer by regulating store-operated calcium entry

  Haitao Luan, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 10 ng/ml FGF (R&D Systems) and 1x B27 supplement (Gibco ...
• Patient-derived tumoroids of advanced high-grade neuroendocrine neoplasms mimic patient chemotherapy responses and guide the design of personalized combination therapies

  Simon L. April-Monn, et al., bioRxiv - Cancer Biology 2022

  Quote: ... PDX1 (1:100, R&D Systems, MAB2419); in a Tris-EDTA buffer for 30min at 100°C for synaptophysin (1:100 ...
• Patient-derived tumoroids of advanced high-grade neuroendocrine neoplasms mimic patient chemotherapy responses and guide the design of personalized combination therapies

  Simon L. April-Monn, et al., bioRxiv - Cancer Biology 2022

  Quote: ... ARX (1:1500, R&D Systems, AF7068), PDX1 (1:100 ...
• ASD modelling in organoids reveals imbalance of excitatory cortical neuron subtypes during early neurogenesis

  Alexandre Jourdon, et al., bioRxiv - Neuroscience 2023

  Quote: ... SOX1 (goat, 1:100, R&D Systems), TBR1 (rabbit ...
• Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis

  Emma Schuster, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PB2 APC (human, R&D Systems #FAB53291A), PB2 FITC (mouse ...
• Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis

  Emma Schuster, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PB2 FITC (mouse, R&D Systems #FAB6836G), Sema4A PE (human/mouse ...
• Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis

  Emma Schuster, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PB2 FITC (mouse, R&D Systems #FAB6836G), CD45 (human ...
• Computational ranking-assisted identification of Plexin-B2 in homotypic and heterotypic clustering of circulating tumor cells in breast cancer metastasis

  Emma Schuster, et al., bioRxiv - Cancer Biology 2023

  Quote: ... PB2 APC (human, R&D Systems #FAB53291A), PB2 FITC (mouse ...
• A multiadjuvant polysaccharide-amino acid-lipid (PAL) subunit nanovaccine generates robust systemic and lung-specific mucosal immune responses against SARS-CoV-2 in mice

  Bhawana Pandey, et al., bioRxiv - Bioengineering 2023

  Quote: ... CF (R&D Systems, Cat# 11058-CV) in 0.05 M carbonate-bicarbonate buffer (1 μg spike/mL ...
• Engineering GliaTrap: a biodegradable non-swelling hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells

  Yusuke Suita, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Human CXCL12 ELISA kit (R&D systems) was used according to the manufacturer’s protocol to quantify total protein in the liposomes before centrifugation and free protein in the receiving tube after the centrifugation ...
• Engineering GliaTrap: a biodegradable non-swelling hydrogel with tuned release of CXCL12 to attract migrating glioblastoma cells

  Yusuke Suita, et al., bioRxiv - Cancer Biology 2023

  Quote: CXCL12 (R&D Systems, 350-NS-050), dissolved in 0.1% BSA in DPBS ...
• ITK signaling regulates a switch between T helper 17 and T regulatory cell lineages via a calcium-mediated pathway

  Orchi Anannya, Weishan Huang, Avery August, bioRxiv - Immunology 2023

  Quote: ... all from R&D Systems (Minneapolis, MN) as described (15) ...
• Primary Ciliary Dyskinesia patient specific hiPSC-derived airway epithelium in Air Liquid Interface culture recapitulates disease specific phenotypes in vitro

  Laura von Schledorn, et al., bioRxiv - Bioengineering 2023

  Quote: ... 10 ng/mL FGF10 (R&D Systems) and 3 μM Chir99021 (provided by the Institute of Organic Chemistry ...
• Enhanced Airway Epithelial Response to SARS-CoV-2 Infection in Children is Critically Tuned by the Cross-Talk Between Immune and Epithelial Cells

  Vladimir G. Magalhães, et al., bioRxiv - Immunology 2023

  Quote: ... IL-6 (7270-IL, R&D Systems), IL-1β (ALX-502-001 ...
• Plasmodium falciparum exploits CD44 as a co-receptor for erythrocyte invasion

  Barbara Baro-Sastre, et al., bioRxiv - Microbiology 2023

  Quote: ... IgG1-Fc (R&D systems 110-HG), or no protein in 200 µl antibody binding and washing buffer (Invitrogen kit 10006D ...
• Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells

  Emma Bergsten, et al., bioRxiv - Microbiology 2023

  Quote: ... 100 ng/mL Noggin (R&D systems), 50 ng/mL recombinant human EGF (R&D systems) ...
• Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells

  Emma Bergsten, et al., bioRxiv - Microbiology 2023

  Quote: ... 500 nM A83-01 (R&D systems), 10 mM nicotinamide (Sigma) ...
• Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells

  Emma Bergsten, et al., bioRxiv - Microbiology 2023

  Quote: ... 500 nM A83-01 (R&D systems), 10 mM nicotinamide (Sigma) ...
• Pro-inflammatory macrophages impair skeletal muscle regeneration in ischemic-damaged limbs by inducing precocious differentiation of satellite cells

  Kevin W. Southerland, et al., bioRxiv - Genomics 2023

  Quote: ... IGF-1 (R&D systems, 791-MG), FGF2 (Thermo Fisher ...
• Binucleated human hepatocytes arise through loss of membrane anchorage to the midbody during endomitosis

  Gabriella Darmasaputra, et al., bioRxiv - Cell Biology 2023

  Quote: ... type 2 (R&D Systems, #3533-001) and cultured and passaged as previously described for Chol-Orgs75 and Hep-Orgs44 ...
• Piezo1 activates non-canonical EGFR endocytosis and signaling

  Carlos Pardo-Pastor, Jody Rosenblatt, bioRxiv - Cell Biology 2023

  Quote: Primaries: pY1173-EGFR (R&D Systems, AF1095), pY1068-EGFR (CST ...
• IL-38 regulates intestinal stem cell homeostasis by inducing WNT signaling and beneficial IL-1β secretion

  Alberto Dinarello, et al., bioRxiv - Cell Biology 2023

  Quote: ... Primary antibody for LGR5 (R&D Systems) was used in combination with peroxidase-conjugated secondary antibodies ...
• A transient dermal niche and dual epidermal programs underlie sweat gland development

  Heather L. Dingwall, et al., bioRxiv - Developmental Biology 2023

  Quote: ... EDAR (1:100, R&D Systems AF745), PDGFRA (1:100 ...
• A transient dermal niche and dual epidermal programs underlie sweat gland development

  Heather L. Dingwall, et al., bioRxiv - Developmental Biology 2023

  Quote: ... PDGFRA (1:100, R&D Systems AF1062), and GFP (1:1000 ...
• Group 2 innate lymphoid cells constrain type 3/17 lymphocytes in shared stromal niches to restrict liver fibrosis

  Julia Sbierski-Kind, et al., bioRxiv - Immunology 2023

  Quote: ... Goat Polyclonal anti-VEGFR3 (R&D Systems), Rabbit Monoclonal anti-mouse Vimentin (EPR3776 ...
• Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2

  Julia Taylor, et al., bioRxiv - Immunology 2023

  Quote: ... CD34 (RQR8)-APC (R&D Systems; FAB7227A), SYTOX™ AADvanced™ Dead Cell Stain (ThermoFisher ...
• Exploration of T-cell immune responses by expression of a dominant-negative SHP1 and SHP2

  Julia Taylor, et al., bioRxiv - Immunology 2023

  Quote: ... CD34 (RQR8)-PE (R&D Systems; FAB7227P), CD34 (RQR8)-APC (R&D Systems ...
• Platelet pannexin-1 channels modulate inflammation during abdominal aortic aneurysm formation

  Lisa Maria Metz, et al., bioRxiv - Cell Biology 2022

  Quote: ... and a MMP9 (#MMpT90, R&D Systems) ELISA were used.
• Distinct axo-protective and axo-destructive roles for Schwann cells after injury in a novel compartmentalised mouse myelinating coculture system

  Clara Mutschler, et al., bioRxiv - Neuroscience 2023

  Quote: βNRG1 (R&D Systems - 396-HB-050)
• Disentangling the Innate Immune Responses of Intestinal Epithelial Cells and Lamina Propria Cells to Salmonella Typhimurium Infection in Chickens

  Kate Sutton, et al., bioRxiv - Immunology 2023

  Quote: ... 50 ng/mL huNoggin (R&D Systems), 10 µM CHIR 99021 and incubated at 37°C ...