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101 - 150 of 1327 citations for 3RS 4 Dimethylamino 3 methyl 2 2 diphenylbutanenitrile Isodidiavalo since 2020

• Rhamnan Sulfate Reduces Atherosclerotic Plaque Formation and Vascular Inflammation

  Nikita P. Patil, et al., bioRxiv - Physiology 2022

  Quote: ... with EGM-2 growth factors (R&D Systems), 10% fetal bovine serum (FBS) ...
• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-10 ...
• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-6 (Peprotech) ...
• Longitudinal Assessment of SARS-CoV-2 Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multi-Cytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity

  Jonah Lin, et al., bioRxiv - Immunology 2022

  Quote: ... 50 U/mL IL-2 (R&D Systems), 10 ng/mL IL-15 (R&D Systems) ...
• NOTCH1 drives immune-escape mechanisms in B cell malignancies

  Maurizio Mangolini, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1000 unit/mL IL-2 (R&D systems), anti-CD3 (2ug/mL) ...
• Membrane-proximal external region is a superior target for mediating effector activity of HIV-1 specific chimeric antigen receptor modified T cells

  Emiko Kranz, et al., bioRxiv - Microbiology 2020

  Quote: ... 30 IU/ml IL-2 (R&D Systems), Glutamax ...
• High-throughput, real-time monitoring of engineered skeletal muscle function using magnetic sensing

  Alec S.T. Smith, et al., bioRxiv - Bioengineering 2022

  Quote: ... 2 ng/ mL IGF-1 (R&D Systems), and 10 ng/ mL HGF (R&D Systems) ...
• Selective modulation of cell surface proteins during vaccinia infection: implications for immune evasion strategies

  Delphine M Depierreux, et al., bioRxiv - Microbiology 2021

  Quote: ... ULBP-2/5/6 (65903, R&D systems), Plexin-B1 (rea728 ...
• Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

  Roberto R. Ricardo-Gonzalez, et al., bioRxiv - Immunology 2021

  Quote: ... or rmIL-13 (2 μg, R&D systems) in calcium- and magnesium-free phosphate buffered saline (PBS) ...
• Novel roles of small extracellular vesicles in regulating the quiescence and proliferation of neural stem cells

  Jingtian Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and N-2 Plus supplement (R&D Systems) in DMEM/F-12 (Gibco ...
• Enhancer Remodeling Promotes Tumor-Initiating Activity in NRF2-Activated Non-Small Cell Lung Cancers

  Keito Okazaki, et al., bioRxiv - Cancer Biology 2020

  Quote: ... N-2 Plus Media Supplement (R&D Systems), Gibco B-27 Supplement (Thermo Fisher Scientific) ...
• Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

  MI Oliveira da Silva, et al., bioRxiv - Neuroscience 2021

  Quote: ... supplemented with 2% N21 (R&D Systems, AR008), 1% penicillin/streptomycin (ThermoFisher Scientific ...
• Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium

  LE. Carter, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 2 μg/mL EGF (R&D Systems)] at 5×10^4 cells/mL in non-adherent 24-well culture plates (Corning ...
• OXPHOS Promotes Apoptotic Resistance and Persistence in T_H17 cells

  Hanna S. Hong, et al., bioRxiv - Immunology 2021

  Quote: ... and mIL-2 (10ng/ml; R&D Systems) for Treg polarization ...
• Cell-matrix adhesion contributes to permeability control in human colon organoids

  James Varani, et al., bioRxiv - Cell Biology 2021

  Quote: ... This antibody (clone #P3H9-2; R&D Systems) has been demonstrated to detect antigen in a variety of epithelia and has been shown to inhibit cell proliferation of both rat and human epithelial cells (32) ...
• Quantitative analysis and genome-scale modeling of human CD4⁺ T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathways

  Partho Sen, et al., bioRxiv - Immunology 2021

  Quote: ... 17 ng/ml IL-2 (R&D Systems) was added to the cultures ...
• Safety switch optimization enhances antibody-mediated elimination of CAR T cells

  Tamer B Shabaneh, et al., bioRxiv - Bioengineering 2022

  Quote: ... 200 IU/ml IL-2 (R&D systems), 120 IU/mL IL-7 (R&D systems) ...
• CRISPRi-Driven Osteogenesis in Adipose-Derived Stem Cells for Bone Healing and Tissue Engineering

  Jacob D. Weston, et al., bioRxiv - Bioengineering 2022

  Quote: ... recombinant BMP-2 (R&D Systems, Minneapolis, MN) at varying doses (0 ...
• Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

  Sara G Romeo, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 2 μM Forskolin (R&D system, 1099) for vascular lineage promotion ...
• Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

  Sara G Romeo, et al., bioRxiv - Cell Biology 2022

  Quote: ... and 2 μM Forskolin (R&D system, 1099). On day 6 ...
• Methionine uptake via SLC43A2 transporter is essential for regulatory T lymphocyte survival

  Afsana Naaz, et al., bioRxiv - Immunology 2022

  Quote: ... Recombinant IL-2 (R&D Systems MN, Canada), Magnetic beads coated with anti-CD3 and anti-CD28 antibodies (Invitrogen ...
• Patient-derived functional immuno-oncology platform identifies responders to ATR inhibitor and immunotherapy combinations in ovarian cancer

  Ashwini S Nagaraj, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Type 2 (# 3533-010-02 R&D systems), or 2.5 mg/mL OmGel at a concentration of 1000 cells / µL and plated as a droplet in 48-well or 96 well plates ...
• A transient modified mRNA encoding Myc and Cyclin T1 induces cardiac regeneration and improves cardiac function after myocardial injury

  Aleksandra Boikova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 5 ng/ml FGF-2 (R&D Systems) and 1 μM CHIR99021 (STEMCELL Technologies) ...
• Multivalent, asymmetric IL-2-Fc fusions provide optimally enhanced regulatory T cell selectivity

  Brian Orcutt-Jahns, et al., bioRxiv - Systems Biology 2022

  Quote: ... IL-2 (R&D Systems, 202-IL-010) or IL-15 (R&D Systems ...
• HIC1 interacts with FOXP3 multi protein complex: a novel mechanism to regulate human regulatory T cell differentiation and function

  Syed Bilal Ahmad Andrabi, et al., bioRxiv - Immunology 2023

  Quote: ... IL-2 (12 ng/ml; R&D Systems); all-trans retinoic acid (ATRA ...
• Reprogramming human B cells with custom heavy chain antibodies

  Geoffrey L. Rogers, et al., bioRxiv - Immunology 2023

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-10 ...
• Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

  Jin Young Lee, et al., bioRxiv - Cancer Biology 2024

  Quote: ... LY6A (R&D systems, 2 μg/ml, AF1226), APOE (1:200 ...
• Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

  Peiyuan Chai, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Siglec-2 Fc chimera protein (R&D Systems), Siglec-3 Fc chimera protein (R&D Systems) ...
• The effects of conditional loss of myosin binding protein H-like on cardiac function

  Hope V. Burnham, et al., bioRxiv - Physiology 2024

  Quote: ... Contactin-2 1:1000 (R&D Systems AF4439), MLC2v 1:2000 (Proteintech 10906-1-AP) ...
• T cell epitope mapping reveals immunodominance of evolutionarily conserved regions within SARS-CoV-2 proteome

  Cansu Cimen Bozkus, et al., bioRxiv - Immunology 2024

  Quote: ... IL-2 (R&D Systems, 10 IU/mL), IL-7 (R&D Systems ...
• Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen

  Yihan Yao, et al., bioRxiv - Biophysics 2024

  Quote: ... Type 2 (3533-010-02 R&D systems) and seeded on glass chamber slides in 20 μL domes and cultured in F-12 Ham Nutrient media with 1% penicillin/streptomycin ...
• nSMase2-mediated exosome secretion shapes the tumor microenvironment to immunologically support pancreatic cancer

  Audrey M. Hendley, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Type 2 (R&D Systems, 3533-005-02).
• Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen

  Yihan Yao, et al., bioRxiv - Biophysics 2024

  Quote: ... Type 2 (3533-010-02 R&D systems) and seeding on glass chamber slides in 20 μL domes ...
• Hypoxia increases the methylated histones to prevent histone clipping and redistribution of heterochromatin during Raf-induced senescence

  Soojeong Chang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and Fluorogenic Peptide Substrate VII: Z-Leu-Arg-4-methyl-7-coumarylamide (Z-LR-AMC)(Catalog # ES008) were purchased from R&D Systems (Minneapolis, MN, USA). The enzyme reactions were initiated upon addition of ice-cold of hrCTSL (96pM ...
• Sprouty2 limits intestinal tuft and goblet cell numbers through GSK3β-mediated restriction of epithelial IL-33

  Michael A. Schumacher, et al., bioRxiv - Physiology 2020

  Quote: Fecal lipocalin-2 levels in distal colon fecal contents were analyzed using Mouse Lipocalin-2 DuoSet ELISA (R&D Systems, DY1857) according to manufacturer provided instructions ...
• Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota that Protects from Metabolic Diseases

  Emelyne Lécuyer, et al., bioRxiv - Immunology 2020

  Quote: ... Lcn-2 levels were quantified in the supernatants using the Duoset murine Lcn-2 ELISA kit (R&D Systems, Minneapolis, MN).
• Bortezomib inhibits lung fibrosis and fibroblast activation without proteasome inhibition

  Loka Raghu Kumar Penke, et al., bioRxiv - Molecular Biology 2021

  Quote: Recombinant human transforming growth factor-β (TGF-β) and fibroblast growth factor-2 FGF-2 were purchased from R&D Systems. BTZ ...
• Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development

  Christina J.F. Courreges, et al., bioRxiv - Immunology 2024

  Quote: ... and 10 μl biotinylated rhIL-2 or biotinylated control protein (from Fluorokine® Biotinylated Human IL-2 Kit, R&D Systems) added to each well ...
• Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes

  Matthew W. Becker, et al., bioRxiv - Bioengineering 2023

  Quote: ... Human IL-2 in the supernatant was measured using a sandwich ELISA kit (Human IL-2 Quantikine ELISA, R&D Systems) according to the manufacturer’s instructions ...
• Untangling the Role of Pathobionts from Bacteroides Species in Inflammatory Bowel Diseases

  Yue Shan, et al., bioRxiv - Microbiology 2023

  Quote: The protein level of LCN-2 was analyzed using a mouse lipocalin-2/NGAL ELISA kit following the manufacturer’s instructions (R&D Systems). The protein level of TNFα was measured using the Mouse TNFα ELISA kit following the manufacturer’s instructions (ThermoFisher).
• Generating human parvalbumin interneurons through 3D glia reprogramming

  Christina-Anastasia Stamouli, et al., bioRxiv - Neuroscience 2024

  Quote: ... USA]) and growth factors (LM-22A4[2 mM, R&D Systems, Minneapolis, MN, USA]; GDNF,[2 ng/ml[R&D Systems, Minneapolis ...
• COUP-TFII regulates early bipotential gonad signaling and commitment to ovarian progenitors

  Lucas G. A. Ferreira, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Cells were cultured for 4 days with 3 μM CHIR (R&D Systems); 3 days with 200 ng/mL FGF9 (R&D Systems) ...
• Human embryonic stem cell-derived cardiomyocytes express SARS-CoV-2 host entry proteins: screen to identify inhibitors of infection

  Thomas L. Williams, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... Cells were aspirated and incubated overnight at 4°C with either: primary goat polyclonal antibody to Human ACE-2 (AF933; R&D Systems; 1:100); primary rabbit monoclonal antibody to TMPRSS2 (ab92323 ...
• Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines

  Paresh C. Shrimali, et al., bioRxiv - Bioengineering 2022

  Quote: ... Supernatant was collected and cytokines were quantified using mouse cytokine & chemokine convenience 6-Plex kit (IL-2, IL-4, IL-5, IL-10, IFN-γ and TNF-α; # LXSAMSM-06, R&D systems) using Luminex xMAP according to manufacturers protocols.
• Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria

  Wiebke Nahrendorf, et al., bioRxiv - Immunology 2020

  Quote: ... We used commercially available ELISA kits to quantify plasma IFNγ (mouse IFNγ platinum ELISA extra sensitive, ebioscience), CXCL10 (mouse IP-10 platinum ELISA, ebioscience) and Angiopoietin-2 (mouse/rat Angiopoietin-2 quantine ELISA kit, R&D Systems). Absorbance was measured using a Multiskan Ascent (MTX Lab systems ...
• Biomarker signatures of quality for nasal chondrocyte-derived engineered cartilage

  M. Adelaide Asnaghi, et al., bioRxiv - Bioengineering 2020

  Quote: ... supplemented with 1 ng/mL transforming growth factor beta-1 (TGF-β1) and 5 ng/mL fibroblast growth factor-2 (FGF-2) (both from R&D Systems) at 37°C and 5% CO2 in a humidified incubator (Thermo Scientific Heraeus ...
• Relative Mutant N501Y SARS-CoV-2 Spike Protein RBD Inhibition of Anti-Spike Protein IgG and ACE-2 Binding to Spike Protein Species

  Melvin E. Klegerman, et al., bioRxiv - Biochemistry 2021

  Quote: Human anti-SP IgG or ACE-2 Fc was mixed with recombinant SARS-CoV-2 spike RBD His tag (R&D Systems) or recombinant SARS-CoV-2 spike RBD (N501Y)-His tag (Sino Biological ...
• Western-style diet impedes colonization and clearance of gut bacterial pathogens

  Jun Zou, Xu Zhao, Juan Noriega, Andrew T. Gewirtz, bioRxiv - Microbiology 2020

  Quote: ... The concentration of LCN-2 in the supernatant was measured by using a DuoSet Mouse Lipocalin-2/NGAL ELISA (R&D Systems) kit ...
• Helicobacter hepaticus as disease driver in a novel CD40-mediated model of colitis

  Verena Friedrich, et al., bioRxiv - Immunology 2020

  Quote: ... The supernatants were analyzed for lipocalin-2 content using Quantikine ELISA kit for mouse Lipocalin-2/NGAL (R&D Systems, Cat: MLCN20).
• Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

  Tomoyoshi Tamura, et al., bioRxiv - Immunology 2022

  Quote: ... Frozen PBMC of post-CA patients were thawed and incubated in the media (RPMI1640 +2% FBS) with human anti-Nectin-2 monoclonal antibody or isotype control (20 μg/mL, both R&D Systems) for 6h ...