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101 - 150 of 3527 citations for 1 2 Dihydro 1 2 tetrahydro 2H pyran 2 yl oxy ethyl 5H tetrazole 5 thione d4 since 2020

• Fecal Microbiota Restoration Modulates the Microbiome in Inflammation-Driven Colorectal Cancer

  Travis J Gates, et al., bioRxiv - Microbiology 2022

  Quote: ... Lcn-2 levels were approximated using a Duoset murine Lcn-2 ELISA kit (R&D Systems, Minneapolis, MN) following the manufacturer’s protocol ...
• Aquaporins enriched in endothelial vacuole membrane regulate the diameters of microvasculature in hyperglycemia

  Changsheng Chen, et al., bioRxiv - Cell Biology 2023

  Quote: ... EBs were formed in an ESC medium depleted of recombinant human FGF-2 (rhFGF-2) (R&D Systems) on day 0 ...
• Identification of a novel enhancer essential for Satb1 expression in T_H2 cells and activated ILC2s

  Aneela Nomura, et al., bioRxiv - Immunology 2023

  Quote: ... 2 ng/mL of IL-2 and 3 ng/mL of TGFβ (R&D systems, 7666-MB-055)) conditions ...
• mRNA Vaccine-Induced SARS-CoV-2 Spike-Specific IFN-γ and IL-2 T-cell Responses are Predictive of Serological Neutralization and are Transiently Enhanced by Pre-Existing Cross-Reactive Immunity

  Philip Samaan, et al., bioRxiv - Immunology 2024

  Quote: ... or CEFTA were supplemented with 10IU/mL of recombinant human IL-2 (rh IL-2; R&D Systems) and 10ng/mL of recombinant human IL-7 (rh IL-7 ...
• Clostridioides difficile binary toxin CDT induces biofilm-like persisting microcolonies

  Jazmin Meza Torres, et al., bioRxiv - Microbiology 2024

  Quote: ... Lcn-2 levels were estimated in the supernatants using Duoset murine Lcn-2 ELISA kit (R&D Systems). Samples from day 0 (before infection ...
• GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

  Anne Helness, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Samples were immuno-precipitated with 2-5 µg of either anti-GFI1 (AF3540, R&D systems), anti-H3K4me1 (ab8895 ...
• Integrating central and peripheral neurons in elongating multi-lineage-organized gastruloids

  Zachary T. Olmsted, Janet L. Paluh, bioRxiv - Developmental Biology 2020

  Quote: ... 2 ng/ml HGF (R&D Systems) and 50 μM Y-27632 (Tocris Bioscience) ...
• A Quantitative Model of Cellular Decision Making in Direct Neuronal Reprogramming

  Adriaan Merlevede, et al., bioRxiv - Systems Biology 2020

  Quote: ... GDNF (2 ng/mL, R&D Systems), NT3 (10 ng/µL ...
• Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

  Endika Prieto-Fernández, et al., bioRxiv - Cell Biology 2021

  Quote: ... syndecan-2 (R&D Systems Cat#: FAB2965P), syndecan-3 (R&D Systems Cat# ...
• A Combined Human Gastruloid Model of Cardiogenesis and Neurogenesis

  Zachary T. Olmsted, Janet L. Paluh, bioRxiv - Developmental Biology 2022

  Quote: ... 2 ng/ml HGF (R&D Systems) and 50 μM Y-27632 (Tocris Bioscience) ...
• Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells

  Anne Marchalot, et al., bioRxiv - Immunology 2020

  Quote: ... 5ng/mL hIL-2 (R&D Systems) and 100ng/mL Mega-CD40 ligand (Enzo Life Sciences ...
• Age-related pathological impairments in induced neurons derived from patients with idiopathic Parkinson’s disease

  Janelle Drouin-Ouellet, et al., bioRxiv - Neuroscience 2021

  Quote: ... GDNF (2 ng/mL, R&D Systems), NT3 (10 ng/μL ...
• Protective heterologous T cell immunity in COVID-19 induced by MMR and Tdap vaccine antigens

  Vijayashree Mysore, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL15(2) (R&D systems, #MAB247) at 5µg/ml ...
• HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A

  Larissa Butler, et al., bioRxiv - Cell Biology 2022

  Quote: ... 20ng/ml FGF-2 (R&D systems), 5μM Y-27632 (Geron) ...
• Localized nanoparticle-mediated delivery of miR-29b normalises the dysregulation of bone homeostasis caused by osteosarcoma whilst simultaneously inhibiting tumour growth

  Fiona E. Freeman, et al., bioRxiv - Bioengineering 2022

  Quote: ... A BMP-2 ELISA (R&D systems) was used to quantify the levels of BMP-2 released by the hydrogels ...
• Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities

  Makrina Daniilidou, et al., bioRxiv - Neuroscience 2022

  Quote: ... ENPP-2 (DENP20, R&D Systems, Europe), TRX-1 (RAB1756 ...
• Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

  Kate Huang, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by IWP-2 (R&D Systems) for 48 hrs (day 1-3) ...
• Binucleated human hepatocytes arise through loss of membrane anchorage to the midbody during endomitosis

  Gabriella Darmasaputra, et al., bioRxiv - Cell Biology 2023

  Quote: ... type 2 (R&D Systems, #3533-001) and cultured and passaged as previously described for Chol-Orgs75 and Hep-Orgs44 ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 2 ng/ml TGFB1 (R&D Systems) and 0.4 μM IWP2 (Selleck Chemicals) ...
• DDHD2 is necessary for activity-driven fatty acid fueling of nerve terminal function

  Mukesh Kumar, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2% N-21 (R&D Systems, AR008), and 4 μM cytosine β-D-arabinofuranoside (Millipore Sigma ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... Sigma)/Laminin (2 µg/mL; R&D Systems)/Fibronectin (1 µg/mL ...
• A Bi-Specific T Cell-Engaging Antibody Shows Potent Activity, Specificity, and Tumor Microenvironment Remodeling in Experimental Syngeneic and Genetically Engineered Models of GBM

  Markella Zannikou, et al., bioRxiv - Immunology 2024

  Quote: ... supplemented with 2% FBS (R&D Systems) and TruStain FcX™ anti-mouse CD16/32 (1:200 ...
• Transgenerational effects of exercise on mouse brain and cognition

  Elisa Cintado, et al., bioRxiv - Neuroscience 2023

  Quote: ... Primary antibodies (DCX, Goat anti-doublecortin, 1:500, Santa Cruz; SOX2, Goat anti-sex determining region Y-box 2, 1:200, R&D Systems; CLR ...
• CRISPR loss of function screening to identify genes involved in human primordial germ cell-like cells development

  Young Sun Hwang, M. Andrés Blanco, Kotaro Sasaki, bioRxiv - Developmental Biology 2022

  Quote: ... 1 mM sodium pyruvate and 0.1 mM 2-mercaptoethanol) containing 50 ng/ml of ACTA (R&D Systems), 3 μM CHIR99021 (Tocris Bioscience ...
• Fluorogenic DNase Sensor Reveals Ubiquitous DNase Activity in Podosomes and Invadopodia

  Kaushik Pal, et al., bioRxiv - Cell Biology 2020

  Quote: ... to RAW264.7 or 2 ng/mL transforming growth factor β-1(240-B/CF, R&D System, USA) to THP-1 for 24-36 hours ...
• Inhibition of LATS Kinases in Ovarian Cancer Activates Cyclin D1/CDK4 and Decreases DYRK1A Activity

  Fatmata Sesay, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Control or shLATS1/2 cells were counted and resuspended in 1% methylcellulose medium (R&D system Cat. # HSC001) prepared in complete growth medium ...
• Quantitative live-cell imaging of secretion activity reveals dynamic immune responses

  Mai Yamagishi, et al., bioRxiv - Biophysics 2022

  Quote: ... The medium was supplemented with 10 ng/ml recombinant mouse IL-2 (rmIL-2) (402-ML, R&D systems) for long-term culture of mouse ILC2s.
• TGFβ limits Myc-dependent TCR-induced metabolic reprogramming in CD8⁺ T cells

  Helen Carrasco Hope, et al., bioRxiv - Immunology 2022

  Quote: ... supernatants were collected and IL-2 concentration was determined using the Mouse DuoSet IL-2 ELISA (R&D Systems), following manufacturer’s instructions ...
• OrBITS: Label-free and time-lapse monitoring of patient derived organoids for advanced drug screening

  Christophe Deben, et al., bioRxiv - Cancer Biology 2022

  Quote: ... Digested cells were washed three times with PBS and resuspended in 2/3 Cultrex Type 2 (R&D Systems) and 1/3 Full Ad-DF+++ medium and plated in drops which were allowed to solidify for 30 minutes at 37°C after which they were overlayed with Full Ad-DF+++ medium ...
• The Alzheimer’s Disease Risk Genes MS4A4A And MS4A6A Cooperate to Negatively Regulate Trem2 and Microglia states

  Dalya Rosner, et al., bioRxiv - Neuroscience 2024

  Quote: ... 50 mL of sample diluted 1:2-1:10 depending on the experiment or human TREM2-Fc standard (R&D Systems #1828-T2-050) were added to the plate and incubated at room temperature for one hour with shaking ...
• Vitamin D receptor protects against dysbiosis and tumorigenesis via the JAK/STAT pathway in intestine

  Yong-Guo Zhang, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Lcn-2 levels were estimated in the supernatants using Duoset murine Lcn-2 ELISA kit (R&D Systems, Minneapolis, MN), as described in our previous study [53].
• Increased receptor affinity and reduced recognition by specific antibodies contribute to immune escape of SARS-CoV-2 variant Omicron

  Anne-Cathrine Vogt, et al., bioRxiv - Immunology 2022

  Quote: ... recombinant SARS-CoV-2 Spike RBD and recombinant SARS-CoV-2 Spike RBD B.1.617.2 L452R T478K were purchased from R&D systems. Proteins were reconstituted as per the manufacturer’s instructions.
• Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis

  Nicolas V. Janto, et al., bioRxiv - Cell Biology 2024

  Quote: ... Lipocalin-2 titration was performed using the DuoSet© ELISA Mouse Lipocalin-2/NGAL kit (R&D Systems, DY1857-05) according to manufacturer’s instructions.
• A conformational switch driven by phosphorylation regulates Ykt6 activity in macroautophagy

  Kaitlyn McGrath, et al., bioRxiv - Cell Biology 2020

  Quote: ... Autophagy was induced by treating the cells for 2 hours in 250nM Torin-1 (R&D Systems, 4247/10) in 1X Hanks’ Balanced salt solution ...
• Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance

  Cameron Geller, et al., bioRxiv - Cancer Biology 2023

  Quote: ... in 2% BSA/PBS solution and the appropriate fluorescently-conjugated secondary antibody (R&D Systems catalog #NL006, 1:200). Coverslips were mounted onto slide with DAPI-containing ProLong Gold media ...
• Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium

  LE. Carter, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 2 μg/mL EGF (R&D Systems)] ...
• DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

  Sarah Talley, et al., bioRxiv - Immunology 2021

  Quote: ... anti-Lipocalin-2 (AF1857-SP, R&D Systems) and anti-β-Actin (sc-8432 ...
• Modeling Cell-Specific Dynamics and Regulation of the Common Gamma Chain Cytokines

  Ali M. Farhat, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 (R&D Systems, 202-IL-010) or IL-15 (R&D Systems ...
• Rhamnan Sulfate Reduces Atherosclerotic Plaque Formation and Vascular Inflammation

  Nikita P. Patil, et al., bioRxiv - Physiology 2022

  Quote: ... with EGM-2 growth factors (R&D Systems), 10% fetal bovine serum (FBS) ...
• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-10 ...
• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-6 (Peprotech) ...
• Longitudinal Assessment of SARS-CoV-2 Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multi-Cytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity

  Jonah Lin, et al., bioRxiv - Immunology 2022

  Quote: ... 50 U/mL IL-2 (R&D Systems), 10 ng/mL IL-15 (R&D Systems) ...
• NOTCH1 drives immune-escape mechanisms in B cell malignancies

  Maurizio Mangolini, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1000 unit/mL IL-2 (R&D systems), anti-CD3 (2ug/mL) ...
• Membrane-proximal external region is a superior target for mediating effector activity of HIV-1 specific chimeric antigen receptor modified T cells

  Emiko Kranz, et al., bioRxiv - Microbiology 2020

  Quote: ... 30 IU/ml IL-2 (R&D Systems), Glutamax ...
• Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

  Roberto R. Ricardo-Gonzalez, et al., bioRxiv - Immunology 2021

  Quote: ... or rmIL-13 (2 μg, R&D systems) in calcium- and magnesium-free phosphate buffered saline (PBS) ...
• Novel roles of small extracellular vesicles in regulating the quiescence and proliferation of neural stem cells

  Jingtian Zhang, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and N-2 Plus supplement (R&D Systems) in DMEM/F-12 (Gibco ...
• Enhancer Remodeling Promotes Tumor-Initiating Activity in NRF2-Activated Non-Small Cell Lung Cancers

  Keito Okazaki, et al., bioRxiv - Cancer Biology 2020

  Quote: ... N-2 Plus Media Supplement (R&D Systems), Gibco B-27 Supplement (Thermo Fisher Scientific) ...
• Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy

  MI Oliveira da Silva, et al., bioRxiv - Neuroscience 2021

  Quote: ... supplemented with 2% N21 (R&D Systems, AR008), 1% penicillin/streptomycin (ThermoFisher Scientific ...
• Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium

  LE. Carter, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 2 μg/mL EGF (R&D Systems)] at 5×10^4 cells/mL in non-adherent 24-well culture plates (Corning ...
• OXPHOS Promotes Apoptotic Resistance and Persistence in T_H17 cells

  Hanna S. Hong, et al., bioRxiv - Immunology 2021

  Quote: ... and mIL-2 (10ng/ml; R&D Systems) for Treg polarization ...