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1351 - 1400 of 2533 citations for Recombinant Human Pro NGF Protein since 2019

• Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma

  Régis Joulia, et al., bioRxiv - Immunology 2024

  Quote: ... was used according to manufacturer instructions or pericytes were directly exposed to recombinant m-MCP6 (R&D systems, matured according to manufacturer instructions ...
• Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during periods of clinical latency

  Melanie Werner-Klein, et al., bioRxiv - Cancer Biology 2020

  Quote: IL6 and soluble IL6RA concentrations were assessed in 100 µl cultured media obtained from HMECs or MCF 10A cells propagated under anchorage dependent or anchorage independent conditions with the Human IL-6 DuoSet or Human sIL-6R alpha DuoSet ELISA kit (R&D Systems, Germany) following the manufacturer’s recommendations.
• The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

  Anders B. Klein, et al., bioRxiv - Physiology 2022

  Quote: GDF15 was measured in human plasma or serum using the Quantikine ELISA Human GDF-15 Immunoassay (ELISA, R&D systems, catalog no. DGD150). In mice ...
• Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

  Anders B. Klein, et al., bioRxiv - Physiology 2020

  Quote: GDF15 was measured in human plasma or serum using the Quantikine ELISA Human GDF-15 Immunoassay (ELISA, R&D systems, catalog no. DGD150). IL-10 was determined in single determinations using multi-spot immunoassay (V-PLEX ...
• Endothelial CXCL5 negatively regulates myelination and repair after white matter stroke

  Guanxi Xiao, et al., bioRxiv - Neuroscience 2020

  Quote: ... Conditioned media from triplicate culture conditions was collected after 48 hours and human CXCL5 levels measured using a human CXCL5 Quantikine Elisa Kit (R&D Systems, Inc.).
• Effects of pasteurization on osteopontin levels in human breastmilk and pasteurized breastmilk products

  Kathleen G. McClanahan, et al., bioRxiv - Physiology 2023

  Quote: The concentration of osteopontin in human milk samples was determined in triplicate using the Human Osteopontin ELISA Kit (R&D Systems, Minneapolis, MN). Samples were diluted 1:100,000 in the provided buffer and analyzed following the manufacturer’s instructions.
• Distinct human stem cell subpopulations drive adipogenesis and fibrosis in musculoskeletal injury

  Steven M. Garcia, et al., bioRxiv - Cell Biology 2024

  Quote: ... Primary antibodies and dilutions for human muscle cross section imaging: anti-human PDGFR alpha antibody 1:100 (R&D Systems, #AF-307-NA), anti-Laminin 2 alpha 1:250 (Abcam ...
• A novel biopolymer for mucosal adjuvant against respiratory pathogens

  Ashley R. Hoover, et al., bioRxiv - Bioengineering 2023

  Quote: ... either 5μg or 2.5μg of the S protein or NC protein (R&D Systems, cat# 10474-CV-050 and cat# 10549-CV-100) ...
• SARS-CoV-2 spike protein induces brain pericyte immunoreactivity in absence of productive viral infection

  Rayan Khaddaj-Mallat, et al., bioRxiv - Neuroscience 2021

  Quote: ... The relative expression profile of 36 human cytokines and chemokines were evaluated using the Proteome Profiler Human Cytokine Array Kit (R&D Systems, ON, Canada). The experiment was performed according to the manufacturer’s protocol ...
• Differential B-cell receptor signaling requirement for adhesion of mantle cell lymphoma cells to stromal cells

  Laia Sadeghi, et al., bioRxiv - Cancer Biology 2020

  Quote: ... The samples were diluted 1:5 using diluent buffer provided by kit and analyzed by sandwich ELISA for human CCL3 and human CCL4 according to manufacturer’s instructions (R&D Systems, DMB00 and DMA00).
• Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5

  Yoshitsugu Oikawa, et al., bioRxiv - Neuroscience 2020

  Quote: The levels of GDF15 and FGF21 were measured using a Quantikine Human GDF15 ELISA Kit and Quantikine Human FGF21 ELISA Kit (R&D Systems, Minneapolis, MN), respectively.
• Maternal obesity driven changes in collagen linearity of breast extracellular matrix induces invasive mammary epithelial cell phenotype

  Jensen N. Amens, et al., bioRxiv - Bioengineering 2022

  Quote: ... was determined using the dot blot-based mouse XL cytokine array kit for the model group breast tissues and human XL cytokine array kit and human XL oncology array kit for the human cell conditioned media following manufacturer’s instructions (R&D Systems, Cat. No: ARY028). Briefly ...
• GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer

  Kelsey E. Huntington, et al., bioRxiv - Cancer Biology 2023

  Quote: Human cell line culture supernatants were analyzed using an R&D systems Human Premixed Multi-Analyte Kit (R&D Systems, Inc., Minneapolis, MN, USA) and a Luminex 200 (RRID ...
• PARP inhibitors enhance reovirus-mediated cell killing through the death-inducing signaling complex (DISC) with an associated NF-κB-regulated immune response

  Joan Kyula-Currie, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cytokine secretion was carried out as a validation from the results of the human cytokine array using a range of human ELISAS from R&D Systems (see below).
• Allosteric modulation of the CXCR4:CXCL12 axis by targeting receptor nanoclustering via the TMV-TMVI domain

  Eva M. García-Cuesta, et al., bioRxiv - Cell Biology 2023

  Quote: The following antibodies were used: monoclonal mouse anti-human CXCR4 (clone 44717) and phycoerythrin-conjugated human CXCR4 (clone 12G5; both from R&D Systems, Minneapolis, MN); purified mouse anti-human CD3 (clone HIT3a ...
• Eicosatetraynoic Acid Regulates Pro-Fibrotic Pathways in an Induced Pluripotent Stem Cell Derived Macrophage:Human Intestinal Organoid Model of Crohn’s Disease

  Ingrid Jurickova, et al., bioRxiv - Molecular Biology 2024

  Quote: ... CCL2 and TL1A were measured using human CCL2 (MCP-1) and human TL1A ELISA kits by R&D Systems (R&D Systems, Minneapolis, MN). SEMA3C was measured using the human SEMA3C ELISA kit by LS Bio (LS Bio ...
• Desert Hedgehog-driven endothelium integrity is enhanced by Gas1 but negatively regulated by Cdon

  Candice Chapouly, et al., bioRxiv - Cell Biology 2020

  Quote: ... goat anti-human Gas1 antibodies (R&D systems, Cat# AF2636), mouse anti-Dhh antibodies (Santa Cruz Biotechnology ...
• Zn²⁺ influx activates ERK and Akt signaling pathways through a common mechanism

  Kelsie J. Anson, Giulia A. Corbet, Amy E. Palmer, bioRxiv - Cell Biology 2020

  Quote: Proteome Profiler Human Phospho-Kinase Array Kit (R&D Systems) was used to measure changes in phosphorylation of 43 kinases upon 40 μM Zn2+ treatment ...
• Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality

  Marie-Christine Bartens, et al., bioRxiv - Immunology 2021

  Quote: ... or Quantikine Human CXCL8 ELISA kit (R&D Systems, USA) for human MØ ...
• Crosstalk between Fat Mass and Obesity-related (FTO) and multiple WNT signaling pathways

  Hyunjoon Kim, Soohyun Jang, Young-suk Lee, bioRxiv - Molecular Biology 2021

  Quote: ... and human R-Spondin1 (R&D Systems #4645-RS-025) were purchased and used ...
• Congruence of location-specific transcriptional programs in intestinal organoids during long-term culture

  Bart van der Hee, et al., bioRxiv - Cell Biology 2019

  Quote: ... 50 ng/ml human epidermal growth factor (R&D systems), 15 nM gastrin ...
• Systemic inflammation and risk of age-associated diseases in people living with HIV on long term suppressive antiretroviral therapy

  Hemalatha Babu, et al., bioRxiv - Immunology 2019

  Quote: ... sCD14 (Human CD14 Quantikine ELISA Kit R&D Systems, UK) and sCD163 (Thermo Scientific™ Pierce™ Human CD163 Kit ...
• Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages

  Joshua D’Rozario, et al., bioRxiv - Immunology 2021

  Quote: ... or anti-human isotype control (Clone: 11711 – R&D systems) were added ...
• Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages

  Joshua D’Rozario, et al., bioRxiv - Immunology 2021

  Quote: ... 0.1μg/ml human anti-CSF1R (Clone: 61701 – R&D systems) or anti-human isotype control (Clone ...
• CITEseq analysis of non-small-cell lung cancer lesions reveals an axis of immune cell activation associated with tumor antigen load and TP53 mutations

  Andrew M. Leader, et al., bioRxiv - Immunology 2020

  Quote: ... Primary antibodies were: anti-human CD10 (200103, R&D systems), DC-Lamp (1010E1.01 ...
• BSG/CD147 and ACE2 receptors facilitate SARS-CoV-2 infection of human iPS cell-derived kidney podocytes

  Titilola D. Kalejaiye, et al., bioRxiv - Bioengineering 2021

  Quote: ... Human/Mouse/Rat/Hamster ACE-2 (R&D systems, AF933), Human TRA-1-85/CD147 (R&D systems ...
• Toxoplasma gondii secreted effectors co-opt host repressor complexes to inhibit necroptosis

  Alex Rosenberg, L. David Sibley, bioRxiv - Microbiology 2020

  Quote: ... Bradyzoites were stimulated with human IFN-γ (R&D systems) at final experimental concentration of 100 U/ml for 6 hr after 5 days in differentiation media prior to being washed with PBS and dislodged with trypsin ...
• Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis

  Jan Ewald, et al., bioRxiv - Systems Biology 2021

  Quote: ... 50ng/mL human fibroblastic growth factor 10 (R&D system), 5% FBS ...
• Overturning the paradigm that IL6 signaling drives liver regrowth while shining light on a new therapeutic target for regenerative medicine

  Jinrui Dong, et al., bioRxiv - Cell Biology 2021

  Quote: ... human soluble gp130 Fc (671-GP-100, R&D systems).
• 3D-imaging reveals conserved cerebrospinal fluid drainage via meningeal lymphatic vasculature in mice and humans

  Laurent Jacob, et al., bioRxiv - Neuroscience 2022

  Quote: ... Goat anti– human PROX1 (AF2727; R&D Systems;1:1000), Rabbit anti-mouse TUJ1 (802001 ...
• FTY720 requires vitamin B₁₂-TCN2-CD320 signaling in astrocytes to reduce disease in an animal model of multiple sclerosis

  Deepa Jonnalagadda, et al., bioRxiv - Neuroscience 2022

  Quote: ... and human TCN2 (R&D systems, cat # 7895-TC-050) were mixed with FTY720 (Novartis) ...
• Anti-inflammatory role of GM1 and modulatory effects of gangliosides on microglia functions

  Danny Galleguillos, et al., bioRxiv - Neuroscience 2020

  Quote: ... and Human IL-1β DuoSet ELISA (DY201, R&D Systems). BDNF and IGF-1 in cell medium and cell lysates of mouse primary microglia were measured using Mature BDNF Rapid ELISA kit (Biosensis ...
• Physiological activation of the nephron central command drives endogenous kidney tissue regeneration

  Georgina Gyarmati, et al., bioRxiv - Physiology 2021

  Quote: Human CCN1 ELISA assay (R&D systems, Minneapolis, MN, USA) was used to analyze urinary CCN1 in undiluted samples collected from control (n=11 ...
• The effect of paracrine factors released by irradiated peripheral blood mononuclear cells on neutrophil extracellular trap formation

  Katharina Klas, et al., bioRxiv - Immunology 2022

  Quote: Human Apoptosis Array kit (R&D Systems, Minneapolis, MN, USA) was performed in accordance to manufacturer’s instructions with no modifications ...
• RSV protects bystander cells against IAV infection by triggering secretion of type I and type III interferons

  Maciej Czerkies, et al., bioRxiv - Immunology 2022

  Quote: ... anti-human interferon beta antibody (R&D Systems, cat. MAB8142).
• Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells

  Yuka Sakata, et al., bioRxiv - Developmental Biology 2022

  Quote: ... 50 ng/mL human sonic hedgehog/SHH (R&D Systems) and 10 μM Y-27632 ...
• Oleocanthal and oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

  Limor Goren, et al., bioRxiv - Cancer Biology 2019

  Quote: ... goat anti-human Cathepsin B antibody (R&D systems AF953), goat anti human cathepsin-D antibody (Santa Cruz sc-6486) ...
• Human caspase-1 autoproteolysis is required for ASC-dependent and -independent inflammasome activation

  Daniel P. Ball, et al., bioRxiv - Immunology 2019

  Quote: ... human NLRP1/NALP1 Sheep polyclonal antibody (R&D systems, AF6788), V5 Rabbit polyclonal Ab (Abcam ...
• Piezo1 channel activates ADAM10 sheddase to regulate Notch1 and gene expression

  Vincenza Caolo, et al., bioRxiv - Cell Biology 2019

  Quote: ... goat anti human VEGFR2 (AF357, R&D system, Minneapolis, MN), mouse anti-human PECAM-1 (CD31 ...
• Proresolving mediators LXB₄ and RvE1 regulate inflammation in stromal cells from patients with shoulder tendon tears

  Stephanie G Dakin, et al., bioRxiv - Cell Biology 2019

  Quote: A human phospho-kinase array kit (R&D Systems ARY003B) was used to investigate the effects of incubating IL-1β stimulated patient derived tendon cells in LXB4 or RvE1 on protein kinase signalling pathways (n=3 donors) ...
• Fusobacterium nucleatum host cell binding and invasion induces IL-8 and CXCL1 secretion that drives colorectal cancer cell migration

  Michael A. Casasanta, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Human IL-8/CXCL8 biotinylated antibody (R&D Systems BAF208) and Human/Primate CXCL1/GROα/KC/CINC-1 biotinylated antibody (R&D Systems BAF275 ...
• Thrombospondin-4 mediates hyperglycemia- and TGF-beta-induced inflammation in breast cancer

  Santoshi Muppala, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and goat anti-human TSP-4 (AF2390, R&D Systems) using Vecta Stain ABC Kit (PK-6104 ...
• Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells

  Christophe Capelle, et al., bioRxiv - Immunology 2020

  Quote: ... Anti-Human phospho NFATC1 (pS172) mAb (MAB5640, R&D Systems) (dilution 1:400) ...
• Thrombospondin-4 mediates hyperglycemia- and TGF-beta-induced inflammation in breast cancer

  Santoshi Muppala, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and goat anti-human TSP-4 (AF2390, R&D Systems). Sections of human tumors were stained with mouse anti-human CD68 (Dako ...
• Molecular and genetic regulation of pig pancreatic islet cell development

  Seokho Kim, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti-human NKX6.1 (R&D systems, AF5857, 1:200,) rabbit anti-MAFB (Bethyl ...
• Human Embryonic Stem Cell-derived Lung Organoids: a Model for SARS-CoV-2 Infection and Drug Test

  Rongjuan Pei, et al., bioRxiv - Microbiology 2020

  Quote: ... 10ng/ml human FGF10 (R&D Systems, 345-FG-025), 10ng/ml human KGF (novoprotein ...
• Myeloid cell-driven nonregenerative pulmonary scarring is conserved in multiple nonhuman primate species regardless of SARS-CoV-2 infection modality

  Alyssa C Fears, et al., bioRxiv - Microbiology 2021

  Quote: ... and Human TGF-β1 Controls (R&D Systems #QC01-1). Each animal’s necropsy BAL supernatant was compared to baseline samples ...
• The Murine Neuronal Receptor NgR1 Is Dispensable for Reovirus Pathogenesis

  Pavithra Aravamudhan, et al., bioRxiv - Microbiology 2021

  Quote: ... goat polyclonal antibody against human NgR1 (R&D Systems, AF1208); and goat polyclonal antibody against mouse NgR1 (R&D Systems ...
• ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment

  Jeffrey D. Steimle, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 1 ng/ml human BMP4 (R&D systems Cat. 314BP), 8 ng/ml human Activin A (R&D systems Cat ...
• ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment

  Jeffrey D. Steimle, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 6 ng/ml human bFGF (R&D systems Cat. 233FB), 1 ng/ml human BMP4 (R&D systems Cat ...