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1351 - 1400 of 2513 citations for 8 N N Diethylamino octan 1 ol since 2019

• Microtissue geometry and cell-generated forces drive patterning of liver progenitor cell differentiation in 3D

  Ian C. Berg, et al., bioRxiv - Bioengineering 2021

  Quote: ... goat anti-Ecadherin (1/50 from stock, R&D Systems AF748), Acti-stain 488 phalloidin (7/1000 from stock ...
• Expansion of CD10^neg neutrophils and CD14⁺HLA-DR^neg/low monocytes driving proinflammatory responses in patients with acute myocardial infarction

  Daniela Fraccarollo, et al., bioRxiv - Immunology 2021

  Quote: ... Antibodies included anti-MMP-9 (AF909; 1:100 R&D Systems); anti IL-1ß (ab9722 ...
• A novel glucocorticoid and androgen receptor modulator reduces viral entry and innate immune inflammatory responses in the Syrian Hamster model of SARS-CoV-2

  Savannah M. Rocha, et al., bioRxiv - Immunology 2021

  Quote: ... goat angiotensin converting enzyme 2 (ACE2;R&D Systems; 1:500), rabbit transmembrane serine protease 2 (TMPRSS2 ...
• Antibody-induced glomerulonephritis is amplified by RTEC-intrinsic IL-17 signaling and restrained by IL-17-mediated induction of the endoribonuclease Regnase-1 (Zc3h12a)

  De-Dong Li, et al., bioRxiv - Immunology 2021

  Quote: ... Immunoblotting Abs: human/mouse anti-Regnase-1 (MAB7875, R&D Systems), human anti-β actin (ab49900 ...
• Release of Notch activity coordinated by IL-1β signalling confers differentiation plasticity of airway progenitors via Fosl2 during alveolar regeneration

  Jinwook Choi, et al., bioRxiv - Cell Biology 2021

  Quote: ... Rat anti-human SCGB1A1/CC10 (1:200, R&D system, MAB4218), Rabbit anti-KDR/VEGFR2 (1:100 ...
• Microtissue geometry and cell-generated forces drive patterning of liver progenitor cell differentiation in 3D

  Ian C. Berg, et al., bioRxiv - Bioengineering 2021

  Quote: ... goat anti-OPN (1/60 from stock, R&D Systems, AF808), goat anti-Ecadherin (1/50 from stock ...
• A clinical stage LMW-DS drug inhibits cell infection by coronaviruses and modulates reactive cytokine release from microglia

  Ann Logan, et al., bioRxiv - Immunology 2022

  Quote: ... MCP-1 and TNFα by Luminex (R&D Systems; LXSAHM-04).
• De-differentiation and Proliferation of Artery Endothelial Cells Drive Coronary Collateral Development

  Gauri Arolkar, et al., bioRxiv - Developmental Biology 2022

  Quote: ... Anti-VEGFR2 (1:125, R&D Systems, Catalog# AF644, RRID: AB_355500). Secondary antibodies ...
• Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

  Nikolaos Kakogiannos, et al., bioRxiv - Cell Biology 2022

  Quote: ... anti-integrin β1 (1:10, AF 2325; R&D Systems; EM), anti-integrin α1 goat (1:500 ...
• Cell surface receptors TREM2, CD14 and integrin α_Mβ₂ drive sinking engulfment in phosphatidylserine-mediated phagocytosis

  Daan Vorselen, et al., bioRxiv - Cell Biology 2022

  Quote: ... or CD14 (R&D systems, 982-CD-100, 1 mg/mL). Strips were washed 3 × (5 minutes agitation each ...
• Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure

  Junedh M. Amrute, et al., bioRxiv - Immunology 2022

  Quote: ... and IL-1b (R&D systems, AF-401-NA, 1:50) co-stained with an appropriate secondary antibody ...
• Polar growth protein Wag31 undergoes changes in homo-oligomeric network topology, and has distinct functions at both cell poles and the septum

  Neda Habibi Arejan, et al., bioRxiv - Microbiology 2022

  Quote: Cultures were stained with 1 μg/mL HADA (R&D systems) for 15 minutes with rolling and incubation at 37°C ...
• Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable

  Kseniia Sarieva, et al., bioRxiv - Neuroscience 2022

  Quote: ... anti-SOX2 (goat, 1:500, R&D Systems, Cat. no. AF2018), anti-PAX6 (mouse ...
• The novel coronary artery disease risk factor ADAMTS-7 modulates atherosclerotic plaque formation by degradation of TIMP-1

  M. Amin Sharifi, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and goat anti-Timp-1 (#cnl0320021; R&D Systems, Minneapolis, USA) as primary antibodies overnight at 4 °C ...
• Asynchronous excitatory neuron development in an isogenic cortical spheroid model of Down syndrome

  Zhen Li, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-SOX2 (1:250 R&D Systems, cat. number: AF2018), rabbit anti-TBR1 (1:250 ...
• Pin1-promoted SUMOylation of RNF168 restrains its chromatin accumulation

  Anoop Singh Chauhan, et al., bioRxiv - Molecular Biology 2022

  Quote: ... mouse anti Pin1 mAb (1:2000 dilution, R&D Systems, MAB2294), rabbit anti Histone H3 polyclonal Ab (1:2000 dilution ...
• Nhlh1 and Nhlh2, a global transcriptional mechanism regulating commissural axon projection via Robo3 activation

  Aki Masuda, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Robo3 polyclonal antibody (R&D Systems, AF3076, 1:200), goat anti-Tag1 polyclonal antibody (R&D Systems ...
• Nhlh1 and Nhlh2, a global transcriptional mechanism regulating commissural axon projection via Robo3 activation

  Aki Masuda, et al., bioRxiv - Neuroscience 2022

  Quote: ... goat anti-Tag1 polyclonal antibody (R&D Systems, AF4439, 1:500), mouse anti-Neurofilament-160KD monoclonal antibody (clone ...
• Antagonism between viral infection and innate immunity at the single-cell level

  Frederic Grabowski, et al., bioRxiv - Systems Biology 2022

  Quote: ... anti-STAT2 (catalog number PAF-ST2; R&D Systems; 1:1000); anti-PKR (clone B-10 ...
• Branched germline cysts and female-specific cyst fragmentation facilitate oocyte determination in mice

  Kanako Ikami, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-GFRα1 goat polyclonal antibody (R&D Systems, AF560, 1:200), anti-PLZF mouse monoclonal antibody (EMD Millipore ...
• Maternal age, obesity and hyperglycaemia are associated with a delay in preimplantation development in a mouse model of type 2 diabetes

  Joaquín Lilao-Garzón, et al., bioRxiv - Developmental Biology 2022

  Quote: ... anti-GATA6 (R&D Systems, Minneapolis, MN, USA, AF1700; 1:200), anti-GATA4 (Santa Cruz ...
• Naïve T lymphocytes chemotax to CCL21 but not to S1P-rich serum

  Nicolas Garcia-Seyda, et al., bioRxiv - Biophysics 2023

  Quote: ... either with 10 μg/mL human ICAM-1 (R&D Systems), 1 μg/mL CCL21 (Miltenyi biotech ...
• A chemical probe to modulate human GID4 Pro/N-degron interactions

  Dominic D.G Owens, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and MAEA (AF7288, R&D Systems, Minneapolis, MN, USA, 1:250). Biotinylated proteins were detected similarly ...
• Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver

  Hitoshi Tsugawa, et al., bioRxiv - Microbiology 2023

  Quote: ... or 1 μg of human recombinant Gas6 protein (R&D Systems) prior to K ...
• Adrenomedullin promotes interneuron migration in a dual human model for hypoxic interneuronopathy of prematurity

  Wojciech P. Michno, et al., bioRxiv - Neuroscience 2023

  Quote: ... and FGF2 (20 ng ml−1, R&D Systems, 233-FB) every day until day 15 ...
• Autophagy mediates cancer cell resistance to doxorubicin induced by the Programmed Death 1/Programmed Death Ligand 1 immune checkpoint axis

  Lori Minassian, et al., bioRxiv - Cancer Biology 2023

  Quote: ... or mouse rPD-1-Fc (R&D Systems #1021-PD-100) for 0 ...
• A shift in the mechanisms controlling hippocampal engram formation during brain maturation

  Adam I. Ramsaran, et al., bioRxiv - Neuroscience 2023

  Quote: ... and mouse anti-HAPLN1 (1:100, R&D Systems, cat# MAB2608) for 24 h or 72 h (for c-Fos experiments ...
• SorLA restricts TNFα release from microglia to shape glioma-supportive brain microenvironment

  Paulina Kaminska, et al., bioRxiv - Neuroscience 2023

  Quote: ... Mouse ICAM-1/CD54 Quantikine ELISA Kit (R&D Systems, #MIC100) was used to determine the levels of sICAM1 in tissue samples.
• Tumor-resident regulatory T cells in pancreatic cancer express the αvβ5 integrin as a targetable activation marker

  Kodai Suzuki, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-mouse NRP-1 Ab (R&D Systems Inc; Minneapolis, MN), Alexa Fluor® 647-conjugated anti-mouse integrin αvβ5 Ab (clone ALULA ...
• Spatial profiling of neuro-immune interactions in gastroenteropancreatic NETs

  Suzann Duan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... TNF-alpha (1:100 Cat #AF-410, RRID:AB_354479, R&D Systems), and phosho-STAT3 Tyr705 (1:100 ...
• A developmentally-inspired hypoxia condition promotes kidney organoid differentiation from human pluripotent stem cells

  Hyeonji Lim, et al., bioRxiv - Bioengineering 2023

  Quote: ... 10 ng mL−1 Activin A (338-AC, R&D Systems) was added for three days ...
• HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

  Estefania Sanchez-Vasquez, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and rabbit anti-Phospho-Histone H2AX (1:500, R&D Systems).
• Central and peripheral tau retention modulated by an anti-tau antibody

  Alexander Solorzano, et al., bioRxiv - Physiology 2023

  Quote: ... goat anti-PDGF Rβ (1: 100, R&D Systems. Cat# AF1042), rabbit anti-OMP (1:100 ...
• Ketolysis is Required for the Proper Development and Function of the Somatosensory Nervous System

  Jonathan Enders, et al., bioRxiv - Neuroscience 2023

  Quote: ... and goat α-TrkA (1:250; R&D Systems, Minneapolis, MN). Slides were incubated with Alexa Fluor 555 tagged donkey-α-rabbit secondary antibody (1:1000 ...
• The super-healing MRL strain promotes muscle growth in muscular dystrophy through a regenerative extracellular matrix

  Joseph G. O’Brien, et al., bioRxiv - Cell Biology 2023

  Quote: ... and Mouse IGF-1 Quantikine ELISA kit (R&D Systems, MG100), respectively ...
• Border-forming wound repair astrocytes

  Timothy M. O’Shea, et al., bioRxiv - Neuroscience 2023

  Quote: Primary antibodies goat anti-A2m (1:300, AF1938; R&D Systems); rabbit anti-Aldh1l1 (1:1000 ...
• Genetically perturbed myelin as a risk factor for neuroinflammation-driven axon degeneration

  Janos Groh, et al., bioRxiv - Neuroscience 2023

  Quote: ... rat anti-O1 AF700 (1:100, FAB1327N-100UG; R&D Systems). Cells were washed twice ...
• A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages

  Izumi Sasaki, et al., bioRxiv - Immunology 2023

  Quote: ... biotinylated anti-IL-1β (BAF401; 1/250 dilution: R&D Systems), anti-Caspase-1 p10 (sc-514 ...
• CAR T cells recognizing CD276 and Dual-CAR T cells against CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models

  Andrea Timpanaro, et al., bioRxiv - Cancer Biology 2023

  Quote: ... goat polyclonal anti-CD276 (1 µg/ml; R&D systems, #AF1027), rabbit monoclonal anti-CD3 (1:200 ...
• An Activity-Based Nanosensor for Minimally-Invasive Measurement of Protease Activity in Traumatic Brain Injury

  Julia A. Kudryashev, et al., bioRxiv - Bioengineering 2022

  Quote: ... and incubated with 1:200 streptavidin-HRP (R&D Systems, DY998) for 1 hour ...
• Robotics-driven manufacturing of cartilaginous microtissues for the bio-assembly of skeletal implants

  Isaak Decoene, et al., bioRxiv - Bioengineering 2023

  Quote: ... and 0.2 ng mL−1 basic FGF-2 (R&D systems). Half of the medium was changed on day 3 ...
• Human Abdominal Subcutaneous-Derived Active Beige Adipocytes Carrying FTO rs1421085 Obesity-Risk Alleles Exert Lower Thermogenic Capacity

  Attila Vámos, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-UCP1 (1:750, R&D Systems, Minneapolis, MN, USA, MAB6158), anti-OXPHOS (1:1000 ...
• Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells

  Liliana M. Sanmarco, et al., bioRxiv - Immunology 2023

  Quote: ... goat anti-HIF-1α (R&D Systems, 1:100, AF1935-SP), rabbit anti-NDUFA4L2 (Proteintech ...
• The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions

  Zheng Fan, et al., bioRxiv - Cell Biology 2022

  Quote: ... and antibodies against CD31 (PECAM1) (AF3628, R&D Systems, 1:250) or ERG (#97249 ...
• BIRC5 Regulates IGFBP-3-Induced Autocrine Loop in Cancer Stem Cells

  Yeon-Jee Kahm, Uhee Jung, Rae-Kwon Kim, bioRxiv - Cancer Biology 2023

  Quote: ... and IGFBP-3 (cat. no. AF675; R&D SYSTEMS, 1:1000) were used for Western blot analysis and Immunocytochemistry assays.
• Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

  Amy H. Chan, et al., bioRxiv - Immunology 2023

  Quote: ... human IL-1β (goat polyclonal antibody, 1:1000, R&D Systems), caspase-1 (D7F10 ...
• The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

  Claudia Carlantoni, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-VE-cadherin (Cat#: AF1002, R&D Systems, 1:1000), rabbit anti-CLDN5 (Cat# ...
• The phosphodiesterase 2A regulates lymphatic endothelial development via cGMP-mediated control of Notch signaling

  Claudia Carlantoni, et al., bioRxiv - Developmental Biology 2023

  Quote: ... goat anti-VE-cadherin (Cat#: AF1002, R&D Systems, 1:200) rabbit anti-LYVE1 (Cat# ...
• Transformation of primary murine peritoneal mast cells by constitutive KIT activation as a result of lost Cdkn2a/Arf expression

  Sandro Capellmann, et al., bioRxiv - Immunology 2023

  Quote: ... and anti-TNF antibodies (1:250, R&D Systems, #BAF-410) diluted in PBS+1% BSA for 45 minutes and 2 hours ...
• Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme

  Amy H. Chan, et al., bioRxiv - Immunology 2023

  Quote: ... human IL-1β (goat polyclonal antibody, 1:1000, R&D Systems), caspase-1 (D7F10 ...