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1251 - 1300 of 10000+ citations for R + SCH 23390 hydrochloride since 2020

• The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation

  Suchitra Mohanty, et al., bioRxiv - Microbiology 2020

  Quote: ... TNF was purchased from R&D Systems. Cycloheximide solution was purchased from Millipore-Sigma.
• Distinct lipid profile, low-level inflammation and increased antioxidant defense as a signature in HIV-1 elite control status

  Maike Sperk, et al., bioRxiv - Microbiology 2020

  Quote: ... C-reactive protein (CRP, R&D systems), and CCL20 (R&D Systems ...
• Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons

  Michael S. Breen, et al., bioRxiv - Pathology 2021

  Quote: ... 40 ng/mL GDNF (R&D Systems), 200 μM ascorbic acid (Sigma-Aldrich ...
• Activin B Promotes the Initiation and Progression of Liver Fibrosis

  Yan Wang, et al., bioRxiv - Pathology 2021

  Quote: ... or TGFβ1 (R&D System, Minneapolis, MN) for six hours ...
• PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1

  Lufei Sui, et al., bioRxiv - Cancer Biology 2021

  Quote: ... Foxp3 (1:200; R&D Systems, MAB8214). After washing ...
• SARS-CoV-2 nucleocapsid protein forms condensates with viral genomic RNA

  Amanda Jack, et al., bioRxiv - Biophysics 2021

  Quote: ... supplemented with 10% FBS (R&D Systems), 1X GlutaMAX (Gibco) ...
• Surface topography is a context-dependent activator of TGF-β signaling in mesenchymal stem cells

  Steven Vermeulen, et al., bioRxiv - Cell Biology 2020

  Quote: ... and mouse TGF-β2 (R&D Systems) were included in the media during cell seeding at a final concentration of 20 ng/ml ...
• Microbiota–modulated enteric neuron translational profiling uncovers a CART+ glucoregulatory subset

  Paul A Muller, et al., bioRxiv - Neuroscience 2020

  Quote: ... CART (1:500, R&D Systems, AF163), CD9 (AF647 ...
• Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice

  Eisuke Okugawa, et al., bioRxiv - Neuroscience 2020

  Quote: ... anti-Reelin (AF3820) from R&D Systems; anti-Cux1 (sc-13024 ...
• A novel soluble ACE2 protein totally protects from lethal disease caused by SARS-CoV-2 infection

  Luise Hassler, et al., bioRxiv - Pathology 2021

  Quote: ... an ACE2 antibody AF933 (R&D Systems) was used (16 ...
• Mycobacterium tuberculosis modifies cell wall carbohydrates during biofilm growth with a concomitant reduction in complement activation

  Thomas Keating, et al., bioRxiv - Immunology 2021

  Quote: ... or recombinant ficolin-3 (R&D systems) or human purified C1q (Comp Tech ...
• Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2

  Xingyue An, et al., bioRxiv - Immunology 2020

  Quote: ... +10% FBS (R&D System, MN, USA), 100 μg/ml NormocinTM (InvivoGen ...
• Endothelial cells promote productive HIV infection of resting CD4+ T cells by an integrin-mediated cell adhesion-dependent mechanism

  Catherine M. Card, et al., bioRxiv - Immunology 2020

  Quote: ... or rhVCAM/Fc chimera (R&D Systems) overnight at 4°C ...
• Type III interferons disrupt the lung epithelial barrier upon viral recognition

  Achille Broggi, et al., bioRxiv - Immunology 2020

  Quote: ... IFNλ2/3 ELISA (R&D Systems DY1789B) and mouse IFNβ ...
• CD4⁺ follicular helper-like T cells are key players in anti-tumor immunity

  D Singh, et al., bioRxiv - Immunology 2020

  Quote: ... anti-human CXCL13 (53610, R&D Systems) and GZMB (REA226 ...
• A reference map of the human proinsulin biosynthetic interaction network

  Duc T. Tran, et al., bioRxiv - Biochemistry 2020

  Quote: ... Goat PRDX4 (R&D System, Minneapolis, MN), Rabbit PRDX4 directly conjugated to Horse Radish Peroxidase (PRDX4-HRP ...
• Aberrant induction of p19^Arf-mediated cellular senescence contributes to neurodevelopmental defects

  Muriel Rhinn, et al., bioRxiv - Developmental Biology 2021

  Quote: ... Sox1 (1:50, R&D systems #AF3369); βIII-tubulin/Tuj1 (1:200 ...
• Maternal Dppa2 and Dppa4 are dispensable for zygotic genome activation but important for offspring survival

  Oana Kubinyecz, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-Dppa4 (R&D Systems, AF3730) 1:100 ...
• HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

  Weifeng Liu, et al., bioRxiv - Immunology 2021

  Quote: ... hBTLA-6×His tag (R&D systems) and hLIGHT-6×His tag proteins (made by the methods described above ...
• Impact of sustained TGFβ receptor inhibition on chromatin accessibility and gene expression in cultured human endometrial MSC

  Raffaella Lucciola, et al., bioRxiv - Cell Biology 2020

  Quote: ... PE-conjugated CD140b (R&D Systems, USA) and APC-conjugated CD90 (BD Pharmingen ...
• Gains of 12p13.31 delay WNT-mediated initiation of hPSC differentiation and promote residual pluripotency in a cell cycle dependent manner

  Alexander Keller, et al., bioRxiv - Cell Biology 2021

  Quote: ... 100ng/mL activin A (R&D systems) and 3μM CHIR99021 (Stem Cell Technologies ...
• The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation

  Leila Revollo, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti P-selectin (R&D Systems, #AF737), anti ITGβ3 (Cell Signaling Technology ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... IGF2 (R&D Systems, AF792, 1:1,000), and Ki67 (Thermo Fisher Scientific ...
• Activation of proneuronal transcription factor Ascl1 in maternal liver ensures a healthy pregnancy

  Joonyong Lee, et al., bioRxiv - Physiology 2021

  Quote: ... ASCL1 (R&D Systems, BAF2567, 1:500), ERK1/2 (Cell Signaling ...
• PPARG in osteocytes is essential for sclerostin expression, bone mass, marrow adiposity and TZD-induced bone loss

  Sudipta Baroi, et al., bioRxiv - Physiology 2020

  Quote: ... (R&D System, Minneapolis, MN; cat #AF1589), or mouse monoclonal β-actin ...
• Blocking IL-10 signaling with soluble IL-10 receptor restores specific lymphoproliferative response in dogs with leishmaniasis caused by Leishmania infantum

  Catiule de Oliveira Santos, et al., bioRxiv - Immunology 2020

  Quote: ... c) canine IL-10 (R&D Systems) at 31.2 ...
• Cystinosin deficient rats recapitulate the phenotype of nephropathic cystinosis

  Jennifer A Hollywood, et al., bioRxiv - Physiology 2021

  Quote: ... CD206 (1:100) (AF2534, R&D systems) in the blocking solution overnight at 4°C in a humidified chamber ...
• Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

  Endika Prieto-Fernández, et al., bioRxiv - Cell Biology 2021

  Quote: ... syndecan-3 (R&D Systems Cat#: FAB3539A) and syndecan-4 (R&D Systems Cat# ...
• Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak

  Kenzo Ivanovitch, et al., bioRxiv - Developmental Biology 2021

  Quote: ... rat anti-CER1 (R&D Systems, MAB1986), goat anti-T (1:250 ...
• Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak

  Kenzo Ivanovitch, et al., bioRxiv - Developmental Biology 2021

  Quote: ... goat anti-DKK1 (R&D Systems, AF1765), rabbit ranti-Aldh1a2 (Abcam ab96060) ...
• A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses

  Huan Du, et al., bioRxiv - Neuroscience 2021

  Quote: ... goat anti-GPNMB (R&D Systems, AF2330), mouse anti-GAPDH (Proteintech Group ...
• CXCL17 is an endogenous inhibitor of CXCR4 via a novel mechanism of action

  Carl W. White, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... VEGF165a was purchased from R&D Systems and synthesis of fluorescent VEGF165a-tetramethylrhodamine (TMR ...
• Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification

  Hsu-Wen Tseng, et al., bioRxiv - Physiology 2021

  Quote: ... Mouse IgG3 isotype (MAB007, R&D systems) and rabbit polyclonal isotype (ab37415 ...
• A Cryptic K48 Ubiquitin Chain Binding Site on UCH37 is Required for its Role in Proteasomal Degradation

  Jiale Du, et al., bioRxiv - Biochemistry 2021

  Quote: Anti PSMB7 (R&D Systems, Cat. #MAB7590)
• Discrete-to-analog signal conversion in human pluripotent stem cells

  Laura Prochazka, et al., bioRxiv - Synthetic Biology 2021

  Quote: ... NODAL (R&D Systems, Catalog # 3218-ND) was added at 100 ng/mL ...
• LIN37-DREAM Prevents DNA End Resection and Homologous Recombination at DNA Double Strand Breaks in Quiescent Cells

  Bo-Ruei Chen, et al., bioRxiv - Cell Biology 2021

  Quote: ... FANCD2 (R&D Systems, MAB93691, 1:1000), BRCA2 for human (Proteintech ...
• PPARdelta signaling activation improves metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes

  Nadeera M. Wickramasinghe, et al., bioRxiv - Cell Biology 2021

  Quote: ... 5 ng/ml bFGF (R&D Systems) and 1 µmol Thiazovivin (Milipore) ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 50ng/ml bFGF (R&D Systems). Cells were harvested and sorted on days 14-15.
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... BMP4 (40 ng/mL; R&D Systems), CHIR99021 (6 μM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... FGF2 (20 ng/mL; R&D Systems), and PI-103 (50 nM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... BMP4 (30 ng/mL; R&D Systems), Forskolin (1 μM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... FGF2 (20 ng/mL; R&D Systems), and PIK90 (100 nM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... BMP4 (30 ng/mL; R&D Systems), TTNPB (75 nM ...
• An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype

  Kathleen C. Keough, et al., bioRxiv - Developmental Biology 2021

  Quote: ... and 50ng/ml bFGF (R&D Systems), filtered and counted using a hemocytometer ...
• Differentiation of human adult-derived stem cells towards a neural lineage involves a de-differentiation event prior to re-differentiation to neural phenotypes

  Carlos Bueno, et al., bioRxiv - Neuroscience 2021

  Quote: ... supplemented with N2-supplement (R&D systems), 0.6% glucose (Sigma-Aldrich) ...
• Single-cell RNA-Seq analysis reveals dual sensing of HIV-1 in blood Axl⁺ dendritic cells

  Flavien Brouiller, et al., bioRxiv - Immunology 2022

  Quote: ... Axl PE (Clone #108724, R&D Systems) CD33 PE-CF594 ...
• Oncomodulin derived from regeneration-associated macrophages in dorsal root ganglia after preconditioning injury promotes sensory axon regeneration in the spinal cord

  Min Jung Kwon, et al., bioRxiv - Neuroscience 2021

  Quote: ... or hyper IL-6 (R&D systems) for 24 h immediately after cell plating ...
• Spatially discrete signalling niches regulate fibroblast heterogeneity in human lung cancer

  CJ Hanley, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Human Recombinant TGF-β1 (R&D Systems) was reconstituted in 4mM HCl ...
• The ETS Transcription Factor ERF controls the exit from the naïve pluripotent state

  M. Vega-Sendino, et al., bioRxiv - Developmental Biology 2021

  Quote: ... 12 ng/ml FGF2 (R&D systems) and 20 ng/ml Activin A (PeproTech ...
• RAL GTPases mediate EGFR-driven intestinal stem cell hyperproliferation and tumourigenesis

  Máté Nászai, et al., bioRxiv - Cancer Biology 2021

  Quote: ... anti-HGFR (R&D Systems, Cat AF276) and anti-EGFR1 (BDPharmingen ...