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51 - 100 of 10000+ citations for 2 Amino 6 chloro 9 3 5 di O p toluoyl beta D 2 deoxyribofurnanosyl purine since 2020

• Cell-type specific in vitro gene expression profiling of stem-cell derived neural models

  James A. Gregory, et al., bioRxiv - Molecular Biology 2020

  Quote: ... and FGF-2 (R&D Systems) on Matrigel-coated plates as described39.
• Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation

  Julio C.Y. Liu, et al., bioRxiv - Molecular Biology 2023

  Quote: ... SUMO2 (R&D Systems, 2 μM), poly-SUMO22-8 chains (R&D Systems ...
• Intraluminal neutrophils limit epithelium damage by reducing pathogen assault on intestinal epithelial cells during Salmonella gut infection

  Ersin Gül, et al., bioRxiv - Immunology 2023

  Quote: Lipocalin-2 ELISA (R&D Systems) was performed to determine gut inflammation from fecal samples according to the manufacturer’s instructions ...
• Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

  Kaja Nicole Wächtershäuser, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Type 2 (BME, R&D Systems) depending on the passaging ratio ...
• Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines

  Paresh C. Shrimali, et al., bioRxiv - Bioengineering 2022

  Quote: ... Supernatant was collected and cytokines were quantified using mouse cytokine & chemokine convenience 6-Plex kit (IL-2, IL-4, IL-5, IL-10, IFN-γ and TNF-α; # LXSAMSM-06, R&D systems) using Luminex xMAP according to manufacturers protocols.
• Modelling Osteoarthritis pathogenesis through Mechanical Loading in an Osteochondral Unit-on-Chip

  Andrea Mainardi, et al., bioRxiv - Bioengineering 2023

  Quote: ... and further supplemented with 5 ng ml -1 of FGF-2 (R&D Systems). Medium was changed twice a week ...
• Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal Cancer

  Victoria A. Stark, et al., bioRxiv - Cancer Biology 2023

  Quote: ... purified sheep IgG (2 mg/mL for LRIG1 R&D Systems #5-001-A), and mouse IgG1-PE conjugate (10 uL for LGR5 ...
• The MS remyelinating drug bexarotene (an RXR agonist) promotes induction of human Tregs and suppresses Th17 differentiation in vitro

  Christof Gaunt, et al., bioRxiv - Immunology 2021

  Quote: ... and 2 ng/ml IL-2 (carrier-free; Tocris R&D Systems). Cells treated with only these functioned as the mock control ...
• Hypothermia protects against ventilator-induced lung injury by limiting IL-1β release and NETs formation

  Nobuyuki Nosaka, et al., bioRxiv - Immunology 2024

  Quote: ... CXCL-2 (Mouse CXCL2/MIP-2 DuoSet ELISA, DY452, R&D Systems), myeloperoxidase (MPO ...
• BRD2 inhibition blocks SARS-CoV-2 infection by reducing transcription of the host cell receptor ACE2

  Avi J. Samelson, et al., bioRxiv - Cell Biology 2021

  Quote: Interferon Beta (R&D systems 8499-IF) was dissolved per the manufacturer’s instructions ...
• MECOM promotes leukemia progression and inhibits mast cell differentiation through functional competition with GATA2

  Kohei Iida, et al., bioRxiv - Molecular Biology 2024

  Quote: ... 10 ng/ml human interleukin-3 (IL-3) and 10 ng/ml human interleukin-6 (IL-6) (R&D Systems).
• Non-classical glycosylation determines intracellular trafficking of APP and Aβ production

  Yuriko Tachida, et al., bioRxiv - Neuroscience 2022

  Quote: ... cell lysates (100 μg of protein) were incubated with O-GlcNAcase (5 μg, R&D Systems) at 37°C for 2 h.
• CLEAN AND FOLDED: OPTIMIZED PRODUCTION OF HIGH QUALITY RECOMBINANT HUMAN INTERFERON-Λ1

  Aram Shaldzhyan, et al., bioRxiv - Bioengineering 2020

  Quote: ... Mouse IL-28 A/B (IFN-lambda 2/3) Du-oSet ELISA (DY1789B, R&D Systems), was used to assess cross-reactivity.
• Integrating central and peripheral neurons in elongating multi-lineage-organized gastruloids

  Zachary T. Olmsted, Janet L. Paluh, bioRxiv - Developmental Biology 2020

  Quote: ... 2 ng/ml HGF (R&D Systems) and 50 μM Y-27632 (Tocris Bioscience) ...
• A Quantitative Model of Cellular Decision Making in Direct Neuronal Reprogramming

  Adriaan Merlevede, et al., bioRxiv - Systems Biology 2020

  Quote: ... GDNF (2 ng/mL, R&D Systems), NT3 (10 ng/µL ...
• Hypoxia reduces cell attachment of SARS-CoV-2 spike protein by modulating the expression of ACE2, neuropilin-1, syndecan-1 and cellular heparan sulfate

  Endika Prieto-Fernández, et al., bioRxiv - Cell Biology 2021

  Quote: ... syndecan-2 (R&D Systems Cat#: FAB2965P), syndecan-3 (R&D Systems Cat# ...
• A Combined Human Gastruloid Model of Cardiogenesis and Neurogenesis

  Zachary T. Olmsted, Janet L. Paluh, bioRxiv - Developmental Biology 2022

  Quote: ... 2 ng/ml HGF (R&D Systems) and 50 μM Y-27632 (Tocris Bioscience) ...
• Splice switching oligonucleotide mediated gene knockdown in B cells and plasma cells

  Anne Marchalot, et al., bioRxiv - Immunology 2020

  Quote: ... 5ng/mL hIL-2 (R&D Systems) and 100ng/mL Mega-CD40 ligand (Enzo Life Sciences ...
• Age-related pathological impairments in induced neurons derived from patients with idiopathic Parkinson’s disease

  Janelle Drouin-Ouellet, et al., bioRxiv - Neuroscience 2021

  Quote: ... GDNF (2 ng/mL, R&D Systems), NT3 (10 ng/μL ...
• Protective heterologous T cell immunity in COVID-19 induced by MMR and Tdap vaccine antigens

  Vijayashree Mysore, et al., bioRxiv - Immunology 2021

  Quote: ... anti-IL15(2) (R&D systems, #MAB247) at 5µg/ml ...
• HDAC6 inhibition partially alleviates mitochondrial trafficking defects and restores motor function in human motor neuron and zebrafish models of Charcot-Marie-Tooth Disease Type 2A

  Larissa Butler, et al., bioRxiv - Cell Biology 2022

  Quote: ... 20ng/ml FGF-2 (R&D systems), 5μM Y-27632 (Geron) ...
• Localized nanoparticle-mediated delivery of miR-29b normalises the dysregulation of bone homeostasis caused by osteosarcoma whilst simultaneously inhibiting tumour growth

  Fiona E. Freeman, et al., bioRxiv - Bioengineering 2022

  Quote: ... A BMP-2 ELISA (R&D systems) was used to quantify the levels of BMP-2 released by the hydrogels ...
• Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities

  Makrina Daniilidou, et al., bioRxiv - Neuroscience 2022

  Quote: ... ENPP-2 (DENP20, R&D Systems, Europe), TRX-1 (RAB1756 ...
• Patient and cell-type specific hiPSC-modeling of a truncating titin variant associated with atrial fibrillation

  Kate Huang, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by IWP-2 (R&D Systems) for 48 hrs (day 1-3) ...
• Binucleated human hepatocytes arise through loss of membrane anchorage to the midbody during endomitosis

  Gabriella Darmasaputra, et al., bioRxiv - Cell Biology 2023

  Quote: ... type 2 (R&D Systems, #3533-001) and cultured and passaged as previously described for Chol-Orgs75 and Hep-Orgs44 ...
• A Spatiotemporal and Machine-Learning Platform Accelerates the Manufacturing of hPSC-derived Esophageal Mucosa

  Ying Yang, et al., bioRxiv - Developmental Biology 2023

  Quote: ... 2 ng/ml TGFB1 (R&D Systems) and 0.4 μM IWP2 (Selleck Chemicals) ...
• DDHD2 is necessary for activity-driven fatty acid fueling of nerve terminal function

  Mukesh Kumar, et al., bioRxiv - Neuroscience 2023

  Quote: ... 2% N-21 (R&D Systems, AR008), and 4 μM cytosine β-D-arabinofuranoside (Millipore Sigma ...
• An iPSC model of fragile X syndrome reflects clinical phenotypes and reveals m⁶A-mediated epi-transcriptomic dysregulation underlying synaptic dysfunction

  Lu Lu, et al., bioRxiv - Neuroscience 2024

  Quote: ... Sigma)/Laminin (2 µg/mL; R&D Systems)/Fibronectin (1 µg/mL ...
• A Bi-Specific T Cell-Engaging Antibody Shows Potent Activity, Specificity, and Tumor Microenvironment Remodeling in Experimental Syngeneic and Genetically Engineered Models of GBM

  Markella Zannikou, et al., bioRxiv - Immunology 2024

  Quote: ... supplemented with 2% FBS (R&D Systems) and TruStain FcX™ anti-mouse CD16/32 (1:200 ...
• Macrophage Function is Regulated by NPM1-mediated 2’-O-methylation

  Paolo Sportoletti, et al., bioRxiv - Cell Biology 2020

  Quote: ... and the mouse chemoattractant macrophage-inflammatory protein-2 (MIP-2, R&D Systems). Migration of cells was evaluated by trypan blue exclusion following incubation.
• Extracellular vesicles from non-neuroendocrine SCLC cells promote adhesion and survival of neuroendocrine SCLC cells

  Lizandra Jimenez, et al., bioRxiv - Cancer Biology 2022

  Quote: ... 2 μg/mL Fibulin-2 (Cat no. 9559-FB-050, R&D Systems) coated ...
• Natural heteroclitic-like peptides are generated by SARS-CoV-2 mutations

  Camilla Tiezzi, et al., bioRxiv - Immunology 2022

  Quote: ... at 37°C in RPMI medium supplemented with 8% human serum and cultured for 7-9 days in the presence of 50 UI/ml of recombinant IL-2 (R&D System).
• Airway tissue stem cells reutilize the embryonic proliferation regulator, Tgfß-Id2 axis, for tissue regeneration

  Hirofumi Kiyokawa, et al., bioRxiv - Developmental Biology 2020

  Quote: ... or Tgfb1/2/3 ligands (10ng/ml, each) (R&D systems, 240-B/302-B2/243-B3) was placed in the upper and lower chambers ...
• Subcellular mRNA localization and local translation of Arhgap11a in radial glial cells regulates cortical development

  Louis-Jan Pilaz, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-Ror-Beta (R&D Systems, N7927), rabbit anti-Laminin (Millipore ...
• Orthosteric STING inhibition elucidates molecular correction of SAVI STING

  Tao Xie, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Interferon-beta (400 IU/mL; R&D Systems) is used to establish 100% maximum values ...
• GFI1 tethers the NuRD complex to open and transcriptionally active chromatin in myeloid progenitors

  Anne Helness, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Samples were immuno-precipitated with 2-5 µg of either anti-GFI1 (AF3540, R&D systems), anti-H3K4me1 (ab8895 ...
• The Cell Surface Receptors Ror1/2 Control Cardiac Myofibroblast Differentiation

  Nicholas W. Chavkin, et al., bioRxiv - Cell Biology 2021

  Quote: Isolated cardiac fibroblasts at Passage (P)2 were treated with 10 ng/mL TGF-β1 (R&D Systems Cat #240-B) in Fibroblast Growth Medium 3 for four days to assess myofibroblast differentiation ...
• The effects of conditional loss of myosin binding protein H-like on cardiac function

  Hope V. Burnham, et al., bioRxiv - Physiology 2024

  Quote: ... The primary antibodies were MyBP-HL [2] and Contactin-2 (R&D Systems AF4439). Secondaries were Alexa Fluor Donkey anti-Rabbit 568 (Thermo Fisher A-10042 ...
• Mast cell regranulation involves a metabolic switch promoted by the interaction between mTORC1 and a glucose-6-phosphate transporter

  Jason A Iskarpatyoti, et al., bioRxiv - Cell Biology 2021

  Quote: ... 5 ng/mL recombinant murine IL-3 (R&D Systems, and 5% stem cell factor-containing supernatant from CHO-KL cells for 4-6 weeks until maturation ...
• Transcriptional heterogeneity of stemness phenotypes in the ovarian epithelium

  LE. Carter, et al., bioRxiv - Cell Biology 2020

  Quote: ... and 2 μg/mL EGF (R&D Systems)] ...
• DSS-induced inflammation in the colon drives a pro-inflammatory signature in the brain that is ameliorated by prophylactic treatment with the S100A9 inhibitor paquinimod

  Sarah Talley, et al., bioRxiv - Immunology 2021

  Quote: ... anti-Lipocalin-2 (AF1857-SP, R&D Systems) and anti-β-Actin (sc-8432 ...
• Modeling Cell-Specific Dynamics and Regulation of the Common Gamma Chain Cytokines

  Ali M. Farhat, et al., bioRxiv - Immunology 2020

  Quote: ... IL-2 (R&D Systems, 202-IL-010) or IL-15 (R&D Systems ...
• Rhamnan Sulfate Reduces Atherosclerotic Plaque Formation and Vascular Inflammation

  Nikita P. Patil, et al., bioRxiv - Physiology 2022

  Quote: ... with EGM-2 growth factors (R&D Systems), 10% fetal bovine serum (FBS) ...
• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-10 ...
• Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes

  Geoffrey L. Rogers, et al., bioRxiv - Molecular Biology 2021

  Quote: ... 10 ng/mL IL-2 (R&D Systems), 50 ng/mL IL-6 (Peprotech) ...
• Longitudinal Assessment of SARS-CoV-2 Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multi-Cytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity

  Jonah Lin, et al., bioRxiv - Immunology 2022

  Quote: ... 50 U/mL IL-2 (R&D Systems), 10 ng/mL IL-15 (R&D Systems) ...
• NOTCH1 drives immune-escape mechanisms in B cell malignancies

  Maurizio Mangolini, et al., bioRxiv - Cancer Biology 2021

  Quote: ... 1000 unit/mL IL-2 (R&D systems), anti-CD3 (2ug/mL) ...
• Membrane-proximal external region is a superior target for mediating effector activity of HIV-1 specific chimeric antigen receptor modified T cells

  Emiko Kranz, et al., bioRxiv - Microbiology 2020

  Quote: ... 30 IU/ml IL-2 (R&D Systems), Glutamax ...
• High-throughput, real-time monitoring of engineered skeletal muscle function using magnetic sensing

  Alec S.T. Smith, et al., bioRxiv - Bioengineering 2022

  Quote: ... 2 ng/ mL IGF-1 (R&D Systems), and 10 ng/ mL HGF (R&D Systems) ...
• Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts

  Roberto R. Ricardo-Gonzalez, et al., bioRxiv - Immunology 2021

  Quote: ... or rmIL-13 (2 μg, R&D systems) in calcium- and magnesium-free phosphate buffered saline (PBS) ...