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801 - 850 of 1927 citations for GFER Human His since 2019

• Segmental flexibility of bispecific T-cell engagers regulates the dynamics of immune synapse formation

  Oskar Staufer, et al., bioRxiv - Immunology 2022

  Quote: ... and TNFα ELISA (human TNF-alpha quantikine ELISA kit, R&D systems, USA) were performed from cell culture supernatants ...
• Brunner Syndrome associated MAOA dysfunction in human induced dopaminergic neurons results in dysregulated NMDAR expression and increased network activity

  Y. Shi, et al., bioRxiv - Neuroscience 2019

  Quote: ... 100ng/mL recombinant human fibroblast growth factor 8a (FGF-8a, R&D system) from day 2 to day 11 ...
• Tail Vein Injections of Recombinant Human Thioredoxin Prevents High Fat-induced Endothelial Dysfunction in Mice

  Rob H.P. Hilgers, bioRxiv - Pharmacology and Toxicology 2019

  Quote: ... and for the rhTrx group with recombinant human Thioredoxin-1 (R&D Systems; 2.5 mg/kg in 100 μL solution in 0.9% NaCl solution) ...
• GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126

  Md. Riaj Mahamud, et al., bioRxiv - Developmental Biology 2019

  Quote: ... and mouse anti-human ANGPT2 (Cat# DY623, R&D Systems, Minneapolis, MN, USA), Rabbit anti-human GAPDH (Cat# PAB13195 ...
• Cell-to-cell diversification in ERBB-RAS-MAPK signal transduction that produces cell-type specific growth factor responses

  Hiraku Miyagi, Michio Hiroshima, Yasushi Sako, bioRxiv - Systems Biology 2020

  Quote: ... or recombinant human NRG-β1/HRG-β1 EGF domain (HRG; R&D Systems) for 5 min at 25°C ...
• The MCMV immunoevasin gp40/m152 inhibits NKG2D receptor RAE-1γ by intracellular retention and cell surface masking

  Natalia Lis, et al., bioRxiv - Cell Biology 2020

  Quote: ... Human IgG Fc APC-conjugated antibody (FAB110A) was purchased from R&D systems. Rabbit anti-calnexin serum was kindly provided by David Williams (Dept ...
• Differences in Activation of Intracellular Signalling in Primary Human Retinal Endothelial Cells Between Isoforms of VEGFA-165

  Wendelin Dailey, et al., bioRxiv - Cell Biology 2020

  Quote: ... Recombinant human VEGFA165a and VEGFA165b were obtained from R&D Systems (Minneapolis, MN). Odyssey Blocking Buffer and an Odyssey Infrared Imager were purchased from LI-COR Biosciences (Lincoln ...
• A conserved SUMO-Ubiquitin pathway directed by RNF4/SLX5-SLX8 and PIAS4/SIZ1 drives proteasomal degradation of topoisomerase DNA-protein crosslinks

  Yilun Sun, et al., bioRxiv - Molecular Biology 2019

  Quote: ... Recombinant human RNF4 was purchased from R&D Systems (Cat. # E3-210-050). Recombinant human ubiquitin was purchased from R&D Systems (Cat ...
• Stromal Oncostatin M axis promotes breast cancer progression

  Angela M. Araujo, et al., bioRxiv - Cancer Biology 2020

  Quote: ... fibroblasts were treated for 4 days with recombinant human OSM (R&D Systems) at 10 ng/μl or vehicle (PBS ...
• Bromodomain and extraterminal protein inhibitor, apabetalone (RVX-208), reduces ACE2 expression and attenuates SARS-CoV-2 infection in vitro

  Dean Gilham, et al., bioRxiv - Pharmacology and Toxicology 2021

  Quote: ... or control recombinant human IgG1 Fc protein (R&D Systems 10499-CV-100) for 30 min at room temperature ...
• Extratubular polymerized uromodulin induces leukocyte recruitment and inflammation in vivo

  Roland Immler, et al., bioRxiv - Immunology 2020

  Quote: ... mouse anti human IgG1 isotype control (clone 11711, R&D Systems, 10μg/ml), rat anti mouse Ly6G (clone 1A8 ...
• Intracellular Galectin-9 controls dendritic cell function by maintaining plasma membrane rigidity

  Laia Querol Cano, et al., bioRxiv - Cell Biology 2019

  Quote: ... goat anti-human Galectin-9 at 20 μg/ml (AF23045, R&D systems); mouse monoclonal Rac1 (240106 ...
• Caspase-8 deficiency induces a switch from TLR3-induced apoptosis to lysosomal cell death in neuroblastoma cell lines

  Marie-Anaïs Locquet, et al., bioRxiv - Molecular Biology 2020

  Quote: ... Human TNF-α (600 lU/ml) from R&D Systems (Minneapolis, MN, USA) was used at 50nM and human sTRAIL/Apo2L from PeproTech (Neuilly-Sur-Seine,France) ...
• LRP1 and SORL1 regulate tau internalization and degradation and enhance tau seeding

  Joanna M. Cooper, et al., bioRxiv - Neuroscience 2020

  Quote: ... Recombinant human SORL1 aa 82-753 protein was purchased from R&D Systems.
• Esrrb is a cell cycle dependent XEN priming factor balancing between pluripotency and differentiation

  Sapir Herchcovici Levi, et al., bioRxiv - Molecular Biology 2021

  Quote: ... Antibodies used were anti-human ESRRB /NR3B2 (R&D systems; PP-H6705-00), anti-GAPDH (Abcam ...
• Priming is dispensable for NLRP3 inflammasome activation in human monocytes

  Anna Gritsenko, et al., bioRxiv - Immunology 2020

  Quote: ... anti-human IL-37 (2 μg/ml, goat polyclonal, R&D Systems, AF1975), anti-human caspase-1 p20 (1:1000 ...
• Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way

  Emmanuel J. Santiago-Burgos, et al., bioRxiv - Microbiology 2022

  Quote: ... the media contained 200 ng/mL of recombinant human IFNγ (R&D Systems). For M2 macrophages ...
• Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts

  Kaj E.C. Blokland, et al., bioRxiv - Cell Biology 2022

  Quote: ... and a human detection OPG antibody (part of cat#DY805, R&D Systems) (29) ...
• Circulating mast cell progenitors migrate to atopic dermatitis-like skin then adapt locally

  Yuki Honda Keith, et al., bioRxiv - Immunology 2022

  Quote: ... and incubated with anti-human/mouse CD117 (c-kit) antibody (R&D Systems), anti-integrinβ7 antibody (FIB504 ...
• Induced pluripotent stem cell-derived astrocytes from patients with schizophrenia exhibit an inflammatory phenotype that affects vascularization

  Pablo Trindade, et al., bioRxiv - Neuroscience 2022

  Quote: ... Human recombinant IL-8 (catalog no. 208-IL-010, R&D Systems, USA) was used at a 5 ng/ml concentration ...
• High CD44 expression identifies rare chemoresistant leukemic cells endowed with enhanced E-Selectin binding in T-ALL

  Julien Calvo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... recombinant E-selectin– human-IgG1 fusion protein (724 ES 100, R&D Systems) was pre-complexed at 5µg/mL with PE-conjugated goat anti-Human IgG diluted at 1/100e (Supplementary Table 2 ...
• Generation of human-pig chimeric renal organoids using iPSC technology

  Koki Fujimori, et al., bioRxiv - Bioengineering 2024

  Quote: ... 1 ng/mL human bone morphogenetic protein 4 (Bmp4) (R&D Systems, Inc.), 20 ng/mL human basic fibroblast growth factor (b-FGF ...
• Signaling events at TMEM doorways provide potential targets for inhibiting breast cancer dissemination

  Chinmay R. Surve, et al., bioRxiv - Cancer Biology 2024

  Quote: ... or the Human M-CSF DuoSet ELISA kit (cat# DY216, R&D Systems). The concentration of protein secreted was interpolated from the standard curve measurements.
• Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer

  Daria Afenteva, et al., bioRxiv - Cancer Biology 2024

  Quote: ... Recombinant Human Interferon alpha 2a (IFN-alpha) was purchased from R&D systems. Cisplatin was purchased from Sigma-Aldrich.
• CDKN1B (p27^kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors

  Elad Horwitz, et al., bioRxiv - Cancer Biology 2024

  Quote: ... rabbit anti Human Phospho-p27/Kip1 Threonine 157 (Cat# AF1555, R&D Systems).
• Galectin-3-binding protein inhibits extracellular heparan 6-O-endosulfatse Sulf-2

  Aswini Panigrahi, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Recombinant human galectin 3 binding protein (R&D Systems, and produced in-house), QuikChange Lightning Site-Directed Mutagenesis Kit (Agilent Technologies) ...
• Neuronal and Astrocyte Insulin-like Growth Factor-1 Signaling Differentially Modulates Ischemic Stroke Damage

  Cellas A. Hayes, et al., bioRxiv - Neuroscience 2023

  Quote: Exogenous IGF-1 Administration: Human recombinant IGF-1 (R&D Systems 291-G1) was reconstituted in sterile saline and 5µls (30µgSE ...
• Epigenetic reprogramming shapes the cellular landscape of schwannoma

  S. John Liu, et al., bioRxiv - Cancer Biology 2022

  Quote: ... and recombinant human IL-2 20 ng/ml (202-IL, R&D Systems). The QCM Leukocyte Migration Assay (MilliporeSigma ...
• Gas6 ameliorates intestinal mucosal immunosenescence to prevent the translocation of a gut pathobiont, Klebsiella pneumoniae, to the liver

  Hitoshi Tsugawa, et al., bioRxiv - Microbiology 2023

  Quote: ... recombinant human Gas6 protein (R&D Systems, Minneapolis, MN, USA, cat# 885-GSB), recombinant mouse Gas6 protein (R&D Systems ...
• GDF3 is an obesity-induced regulator of TGFβ superfamily signaling

  Deepti Ramachandran, et al., bioRxiv - Cell Biology 2023

  Quote: ... Human Fc-fusion constructs of each receptor were purchased from R&D Systems (TGFβRII-Fc ...
• KAT6A mutations drive transcriptional dysregulation of cell cycle and Autism risk genes in an Arboleda-Tham Syndrome cerebral organoid model

  Aileen A. Nava, et al., bioRxiv - Genetics 2023

  Quote: ... recombinant human EGF at 20 ng/mL (R&D systems #236-EG-200), and recombinant human FGF2 at 20 ng/uL (R&D systems #233-FB-010).
• Proximity labelling and evolutionary evidence reveal insights into IL-1α nuclear networks and function

  Rose Wellens, et al., bioRxiv - Immunology 2023

  Quote: Goat anti-human IL-1α (AF-200-NA) was from R&D Systems. Rabbit anti-human BirA (11582-RP01 ...
• Unlocking the Role of Endothelial MPL Receptor and JAK2V617F Mutation: Insights into Cardiovascular Dysfunction in MPNs and CHIP

  Haotian Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... and goat anti-human CD144 (Cat. AF938, R&D Systems; dilution 1:250). After three washes with PBS ...
• A hybrid combination of in vitro cultured buccal mucosal cells using two different methodologies, complementing each other in successfully repairing a stricture-inflicted human male urethral epithelium

  Akio Horiguchi, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... Human IGF-I/IGF-1 Quantikine ELISA Kit (R&D systems, Cat#DG100B) was employed.
• Comprehensive multi-platform tyrosine kinase profiling reveals novel actionable FGFR aberrations across pediatric and AYA sarcomas

  Ashleigh M Fordham, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and Proteome Profiler Human Phospho-Kinase Array Kit (R&D Systems, Cat#ARY003C) were performed according to manufacturer’s protocols ...
• Accurate quantification of lysyl oxidase concentration in human tissue

  Yimin Yao, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Recombinant human (rh) TGF-β (10 ng/mL, R&D Systems, 7754-BH) was applied to NHLF cell line only to induce LOX expression ...
• Hypoxia-inducible factor 1 signaling drives placental aging and can provoke preterm labor

  Erin J. Ciampa, et al., bioRxiv - Physiology 2023

  Quote: ... Cells were stimulated by addition of recombinant human IL-1β (R&D Systems) and/or filter-concentrated JAR cell conditioned media as indicated ...
• Defining T cell receptor repertoires using nanovial-based affinity and functional screening

  Doyeon Koo, et al., bioRxiv - Bioengineering 2023

  Quote: ... or 1000 ng/mL of recombinant human IFN-γ (R&D Systems, 285IF100) and TNF-α (R&D Systems ...
• BDNF signaling in correlation-dependent structural plasticity in the developing visual system

  Elena Kutsarova, et al., bioRxiv - Neuroscience 2023

  Quote: ... 50 μg/mL TrkB-Fc (Recombinant Human Chimera, 688-TK, R&D Systems) was injected intraventricularly ...
• IL-33 drives polyfunctionality and antitumor activity of a unique ST2+ NK cell population

  Anaïs Eberhardt, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Sections were then stained with goat anti-human IL-33 (R&D Systems, # AF3625 ...
• CCR1 Mediates Müller Cell Activation and Photoreceptor Cell Death in Macular and Retinal Degeneration

  Sarah Elbaz-Hayoun, et al., bioRxiv - Immunology 2023

  Quote: ... mouse anti-human CCR1 (25 µg/ml; mab145, R&D Systems, Minneapolis, MN), rat anti-mouse CCR1 (25 µg/ml ...
• Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant SMO and GLI into Glioma Primary Cilia

  Ping Shi, et al., bioRxiv - Cancer Biology 2022

  Quote: ... recombinant human SHH (high activity (R&D Systems: Cat # 8908-SH-005/CF), and fixed after indicated treatment durations and processed as described below ...
• Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis

  Jyothi Padiadpu, et al., bioRxiv - Systems Biology 2023

  Quote: ... BTC at 40 ng/mL (human recombinant Betacellulin protein, R&D systems, MN), or combinations of all for 6 hours ...
• Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate Cells

  Hyeon Ryoo, Gregory H. Underhill, bioRxiv - Bioengineering 2023

  Quote: ... or 4 µg mL-1 human PDGFR beta antibody (AF385, R&D Systems) and 10 µg mL-1 human/mouse/rat alpha-smooth muscle actin antibody (MAB1420 ...
• Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy

  M Fejzo, et al., bioRxiv - Genetics 2023

  Quote: ... The calibrator is recombinant human GDF15 from R&D Systems (Bio-Techne, USA). MSD Ansh antibody Total GDF15 between batch imprecision based on in-house sample pool controls 10.2% at 552.4 pg/ml ...
• Conserved allomorphs of MR1 drive specificity of MR1-restricted TCRs

  Terri V Cornforth, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and for granzyme B using human Granzyme B DuoSet ELISA (R&D Systems). All ELISAs were performed as per manufacturer’s instructions ...
• Integrated histopathology, spatial and single cell transcriptomics resolve cellular drivers of early and late alveolar damage in COVID-19

  Jimmy Tsz Hang Lee, et al., bioRxiv - Pathology 2023

  Quote: ... were treated with recombinant human osteopontin (rhOPN; R&D Systems, 1433-OP-050) for 24 hours in serum and supplement-free growth medium (EGM ...
• A 2-Hydroxybutyrate- mediated feedback loop regulates muscular fatigue

  Brennan J Wadsworth, et al., bioRxiv - Physiology 2023

  Quote: ... Activity of BCAT was assessed using recombinant human BCAT2 (rhBCAT2; R&D Systems)41 ...
• Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer’s disease, restores synapse integrity and memory in a disease mouse model

  Nuria Martin-Flores, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-Human DKK-3 (1:1,000, R&D Systems, Cat# AF1118, RRID:AB_354610), rabbit anti-GAPDH (1:5,000 ...
• KCNN4 links PIEZO-dependent mechanotransduction to NLRP3 inflammasome activation

  Li Ran, et al., bioRxiv - Immunology 2023

  Quote: ... Anti-human IL-1β antibody (AF-201-NA) was from R&D Systems. Anti-murine IL-1β antibody (5129-100 ...