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6451 - 6500 of 10000+ citations for 6 AMINO 6 DEOXY 1 2 3 4 DI O ISOPROPYLIDENE D GALACTOPYRANOSIDE since 2019

• Bioengineering of a human innervated cardiac muscle model

  Lennart Valentin Schneider, et al., bioRxiv - Bioengineering 2023

  Quote: ... 5 ng/mL BMP4 (R&D systems, #314-BP), 1 μM CHIR99021 (Stemgent ...
• GABAergic LRP1 is a key link between obesity and memory function

  Aaron Aykut Uner, et al., bioRxiv - Neuroscience 2023

  Quote: ... apolipoprotein J (ApoJ) (MCLU00, R&D Systems, Minneapolis, MN), Aβ40 (KMB3481 ...
• SCF^FBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

  Ben Jin, et al., bioRxiv - Biochemistry 2023

  Quote: ... rhIL-17E (R&D Systems, #8134-IL-025/CF), or rhIL-17F (R&D Systems ...
• Skin mesenchymal niches maintain and protect AML-initiating stem cells

  Lakshmi Sandhow, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and mouse StemXVivo ostegenic supplement (CCM009; R&D Systems) under normoxic condition for 14-21 days ...
• Exogenous Recombinant N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B; ARSB) Inhibits Progression of B16F10 Cutaneous Melanomas and Modulates Cell Signaling

  Sumit Bhattacharyya, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Recombinant bioactive ARSB (R&D Systems, Minneapolis, MN, USA) in normal saline (n=12 ...
• Human iPSC-derived neural stem cells display a radial glia-like signature in vitro and favorable long-term safety in transplanted mice

  Marco Luciani, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-SSEA4 APC-conjugated antibody (FAB1435a, R&D Systems). For Annexin V/7AAD analysis ...
• Rescue of FTLD-associated TDP-43 pathology and neurodegeneration by peripheral AAV-mediated expression of brain-penetrant progranulin

  Marvin Reich, et al., bioRxiv - Neuroscience 2023

  Quote: ... or a rat anti-mPGRN (R&D Systems, MAB25571) antibody at 0.25 µg/mL followed by sulfo-tagged secondary antibodies (anti-rabbit and anti-rat respectively) ...
• Enteric glial hub cells coordinate intestinal motility

  Marissa A. Scavuzzo, et al., bioRxiv - Neuroscience 2023

  Quote: ... 20ng/mL FGF2 (R&D Systems, 23-3FB-010M), and 1x penicillin/streptomycin (Thermo Fisher ...
• Exploring the Role of MMP9 and its Association with TGFβ Signalling in Patients with Mesial Temporal Lobe Epilepsy-Hippocampal Sclerosis

  Debasmita Paul, et al., bioRxiv - Neuroscience 2023

  Quote: Enzyme-linked immunosorbent assay (R&D System, United States) was performed according to the instructions to measure the protein expression level of MMP9 and TIMP1 in resected hippocampi of non-seizure controls and patients with MTLE-HS ...
• Designer small molecule control system based on Minocycline induced disruption of protein-protein interaction

  Ram Jha, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Human CD34 APC-conjugated antibody (R&D system, FAB7227A), Human CD34 Alexa Fluor® 488-conjugated antibody ...
• Ets1 and IL17RA cooperate to regulate autoimmune responses as well as skin immunity to Staphylococcus aureus

  Michael Battaglia, et al., bioRxiv - Immunology 2023

  Quote: ... 10μg/ml anti-TGFβ (R&D Systems, clone 1D11), 30ng/ml IL6 (Shenandoah Biotechnology) ...
• Spatial proteomics reveals heterogeneity in neural markers underpinning high-fat diet-induced myopathy in male mice

  Lydia Hardowar, et al., bioRxiv - Physiology 2023

  Quote: ... and CD31 (R&D systems, U.K, goat anti-PECAM1) and UV-cleavable oligo-labelled detection antibody panel (GeoMx Neural Cell Profiling Panel) ...
• Knock-down of a regulatory barcode shifts macrophage polarization destination from M1 to M2 and increases pathogen burden upon S. aureus infection

  Sathyabaarathi Ravichandran, et al., bioRxiv - Systems Biology 2023

  Quote: ... IL4 (#204-IL) were purchased from R&D Systems. THP-1 human monocytic cell line was obtained from National Centre for Cell Sciences ...
• Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging

  Sher Bahadur Poudel, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... and 60ng/ml RANKL (R&D Systems; cat# 462TEC010) to induce osteoclastogenesis in the presence of different concentrations (0 ...
• An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons

  Holly N. Cukier, et al., bioRxiv - Genetics 2023

  Quote: ... Human/Mouse/Rat SOX1 Antibody (R&D Systems, # AF3369), Purified anti-Tubulin β-3 (TUBB3 ...
• Monomeric amyloid-β inhibits microglial inflammatory activity in the brain via an APP/heterotrimeric G protein-mediated pathway

  Hyo Jun Kwon, Devi Santhosh, Zhen Huang, bioRxiv - Neuroscience 2023

  Quote: ... goat anti-MMP2 (R&D Systems; 5 μg/ml), rabbit anti-Calretinin (Chemicon ...
• APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia

  Michael S. Haney, et al., bioRxiv - Neuroscience 2023

  Quote: ... murine IL-34 (100 ng/mL, R&D Systems),) ...
• LINKIN-associated proteins necessary for tissue integrity during collective cell migration

  Chieh-Hsiang Tan, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse anti-ITFG1 antibody (ITFG1_Ab2) (R&D Systems, MAB89001), Rabbit anti-RUVBL1 antibody (Proteintech ...
• GATA1 knockout in human pluripotent stem cells generates enhanced neutrophils to investigate extracellular trap formation

  Thomas C. Harper, et al., bioRxiv - Immunology 2023

  Quote: ... 50 ng/ml VEGF (R&D Systems, 293-VE) and 2 μM CHIR99021 (Tocris ...
• Microglial synaptic pruning in the nucleus accumbens during adolescence sex-specifically influences splenic immune outcomes

  J. M. Kirkland, et al., bioRxiv - Neuroscience 2023

  Quote: ... and IFNγ ELISAs were purchased from R&D Systems (#R2000 ...
• Synthetic Frizzled agonist and LRP antagonist for high-efficiency Wnt/β-catenin signaling manipulation in organoid cultures and in vivo

  Quanhui Dai, et al., bioRxiv - Synthetic Biology 2023

  Quote: ... and 100 ng/mL TNF-α (R&D Systems) in the absence or presence of 50 ng/mL sWnt ...
• Personalized models of breast cancer desmoplasia reveal biomechanical determinants of drug penetration

  Giovanni S. Offeddu, et al., bioRxiv - Bioengineering 2023

  Quote: ... Recombinant human IL8 (#208-IL-010, R&D Systems), IL12 (#219-IL-005 ...
• Epigenetic regulation of Leukocyte associated immunoglobulin-like receptors 1 and 2 by interferon signaling in macrophages and T cells

  Hannah K. Dorando, et al., bioRxiv - Immunology 2023

  Quote: ... 20ng/mL mouse IFN-β (8234MB010, R&D Systems), 20ng/mL mouse TNF-α (410MT010 ...
• Epigenetic regulation of Leukocyte associated immunoglobulin-like receptors 1 and 2 by interferon signaling in macrophages and T cells

  Hannah K. Dorando, et al., bioRxiv - Immunology 2023

  Quote: ... 20ng/mL mouse TNF-α (410MT010, R&D Systems), 100ng/mL LPS (L3012 ...
• Humoral correlates of protection against Mycobacterium tuberculosis following intravenous Bacille Calmette-Guérin vaccination in rhesus macaques

  Edward B. Irvine, et al., bioRxiv - Immunology 2023

  Quote: ... and Zaire ebolavirus glycoprotein (R&D Systems, 9016-EB).
• GATA1 knockout in human pluripotent stem cells generates enhanced neutrophils to investigate extracellular trap formation

  Thomas C. Harper, et al., bioRxiv - Immunology 2023

  Quote: ... 100 ng/ml SCF (R&D Systems, 255-SC), 20 ng/ml SHH (PeproTech ...
• Non-genetic differences underlie variability in proliferation among esophageal epithelial clones

  Raúl A. Reyes Hueros, et al., bioRxiv - Systems Biology 2023

  Quote: ... Human recombinant DKK1 (rhDkk, R&D Systems, 5439-DK) was reconstituted at 100µg/mL in 0.1% bovine serum albumin (BSA ...
• CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan

  Linda Heilig, et al., bioRxiv - Microbiology 2023

  Quote: ... CCL4 (MIP-1β, R&D Systems, Minneapolis, MN, USA), CCL5 (RANTES ...
• Altered DNA methylation underlies monocyte dysregulation and innate exhaustion memory in sepsis

  Blake A. Caldwell, Yajun Wu, Jing Wang, Liwu Li, bioRxiv - Immunology 2023

  Quote: ... and TREM2 (Alexa Fluor 700; R&D Systems #FAB17291N). For panel 3 ...
• Engagement of sialylated glycans with Siglec receptors on myeloid suppressor cells inhibit anti-cancer immunity via CCL2

  Ronja Wieboldt, et al., bioRxiv - Immunology 2023

  Quote: ... Siglec-9 blocking antibody (Clone 191240, R&D Systems) was added at a final concentration of 10 µg/mL ...
• SCF^FBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

  Ben Jin, et al., bioRxiv - Biochemistry 2023

  Quote: ... rhIL-17B (R&D Systems, #8129-IL-025/CF), rhIL-17C (R&D Systems ...
• SCF^FBXW11 complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

  Ben Jin, et al., bioRxiv - Biochemistry 2023

  Quote: ... rhIL-17C (R&D Systems, #9640-IL-025/CF), rhIL-17E (R&D Systems ...
• Functioning human lung organoids model pulmonary tissue response from carbon nanomaterial exposures

  Rahaf Issa, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... All growth factors were purchased from R&D systems, unless otherwise stated ...
• The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase

  Yue Zhou, et al., bioRxiv - Microbiology 2023

  Quote: ... 0.4 ng CD73 nucleotidase (R&D systems, cat# EA002), 1 mM MnCl2 ...
• Time- and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification

  Yale S. Michaels, et al., bioRxiv - Immunology 2023

  Quote: ... IL-11 (5ng/mL, R&D Systems, 218-IL), TPO (30ng/mL ...
• Vascularised Cardiac Spheroids-on-a-Chip for Testing the Toxicity of Therapeutics

  Stefania Di Cio, et al., bioRxiv - Bioengineering 2023

  Quote: ... Alexa Fluor® 488-anti-podocalyxin (R&D Systems); Phalloidin–Tetramethylrhodamine B isothiocyanate (Merck) ...
• Mechanically activated bone cells drive vessel formation via an extracellular vesicle mediated mechanism

  N. Shen, et al., bioRxiv - Bioengineering 2023

  Quote: ELISA kits for mouse VEGF (R&D Systems, UK) were used according to the manufacturer’s instructions ...
• A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance

  Felix van der Krift, et al., bioRxiv - Biochemistry 2023

  Quote: ... Organoids were maintained in Cultrex BME (R&D systems) and dissected using TrypLE (ThermoFisher ...
• Mechanisms of transcription control by distal enhancers from high-resolution single-gene imaging

  Lingling Cheng, et al., bioRxiv - Biophysics 2023

  Quote: ... 15% fetal bovine serum (FBS, R&D Systems, S10250), 0.1 mM 2-mercaptoethanol (Thermo Fisher Scientific 21985023) ...
• Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism

  Daniel Levy, et al., bioRxiv - Bioengineering 2023

  Quote: ... TNF-⍰ (DY410; R&D Systems Incorporated, Minneapolis, MN, USA), CCL5 (DY478 ...
• Induced pluripotent stem cell-derived extracellular vesicles promote wound repair in a diabetic mouse model via an anti-inflammatory immunomodulatory mechanism

  Daniel Levy, et al., bioRxiv - Bioengineering 2023

  Quote: ... CCL5 (DY478; R&D Systems Incorporated, Minneapolis, MN, USA), and IFN-β (DY8234 ...
• Sustained In Vivo Perfusion of a Re-Endothelialized Tissue Engineered Kidney Graft in a Human-Scale Animal Model

  Joseph S. Uzarski, et al., bioRxiv - Bioengineering 2023

  Quote: ... epidermal growth factor (EGF) (R&D Systems, #236-EG), recombinant insulin-like growth factor (R3-IGF ...
• Multivalent, asymmetric IL-2-Fc fusions provide optimally enhanced regulatory T cell selectivity

  Brian Orcutt-Jahns, et al., bioRxiv - Systems Biology 2022

  Quote: ... or IL-15 (R&D Systems, 247-ILB-025) were diluted in RPMI-1640 in the absence of FBS ...
• The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo

  Martin S. Minns, et al., bioRxiv - Microbiology 2023

  Quote: ... and 10 ng/mL M-CSF (R&D Systems). On Day 2 and Day 4 ...
• The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus

  Thomas M. Li, et al., bioRxiv - Immunology 2023

  Quote: ... 37.5 ng IFN-κ (R&D Systems, Minneapolis, MN) was dissolved in DMSO (Sigma Aldrich ...
• Restoring glucose homeostasis with stomach-derived human insulin-secreting organoids

  Xiaofeng Huang, et al., bioRxiv - Cell Biology 2022

  Quote: ... was supplemented with 18% FBS (R&D systems, S11150), 10% R-Spondin-2 conditioned medium ...
• Adhesion-based capture stabilizes nascent microvilli at epithelial cell junctions

  Caroline S. Cencer, et al., bioRxiv - Cell Biology 2023

  Quote: ... and 10% fetal bovine serum (FBS) (R&D Systems) while CACO-2BBE (human colonic adenocarcinoma ...
• Peripheral extracellular vesicle-derived miR-150-3p exacerbates acute kidney injury following acute pancreatitis by promoting ferroptosis through FTH1 signaling

  Ji-tao Cui, et al., bioRxiv - Cell Biology 2023

  Quote: ... Standard diagnostic kits (R&D Systems, Minneapolis, MN, USA) were used to measure GSH and MDA contents in pancreas samples and peripheral blood ...
• Mutations in an unrecognized internal NPT2A PDZ motif disrupt phosphate transport causing congenital hypophosphatemia

  W Bruce Sneddon, et al., bioRxiv - Cell Biology 2023

  Quote: ... was obtained from R&D Systems (2604-FG-025).
• Bacterial meningitis in the early postnatal mouse studied at single-cell resolution

  Jie Wang, Amir Rattner, Jeremy Nathans, bioRxiv - Immunology 2023

  Quote: ... goat anti-VEGFR2/KDR (R&D Systems AF644-SP); sheep anti-FOXP2 (R&D Systems AF5647-SP) ...