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251 - 300 of 1728 citations for 5 Pyrimidinecarbonitrile 2 4 diamino 6 methoxy 9CI since 2019

• Selenium reduction of ubiquinone via SQOR suppresses ferroptosis

  Namgyu Lee, et al., bioRxiv - Biochemistry 2023

  Quote: ... SK-Hep1 cells were treated with vehicle or 6 µM selenite (Santa Cruz) in fresh media and incubated in the CO2 incubator ...
• Loss of TMEM106B exacerbates Tau pathology and neurodegeneration in PS19 mice

  Tuancheng Feng, Huan Du, Fenghua Hu, bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-acetylated alpha Tubulin Antibody (6-11B-1) (Santa Cruz, sc-23950), mouse anti-acetylated Tubulin (Lys40 ...
• An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

  Thomas J. Kucharski, et al., bioRxiv - Cell Biology 2024

  Quote: ... mouse anti-PP2A B56 Beta (Santa Cruz E-6; IB at 1:500), mouse anti-PP2A B56 Gamma (Santa Cruz A-11 ...
• Clinical and In Situ Characterization of Hepatitis Delta Virus in Sjogren’s Syndrome

  Matthew C. Hesterman, et al., bioRxiv - Microbiology 2022

  Quote: ... mouse monoclonal anti-Aquaporin 5 (APQ-5) antibody (1:400; Santa Cruz Biotechnology Inc, SC-514022), mouse monoclonal anti-Cytokeratin 7 (CK-7 ...
• Evolutionary transcriptomics implicates HAND2 in the origins of implantation and regulation of gestation length

  Mirna Marinić, et al., bioRxiv - Evolutionary Biology 2020

  Quote: ... p-Erk1/2 (also known as MAPK1/2; Santa Cruz SC-23759-R) at 1:1000 dilution in blocking buffer ...
• Essential role of Bone morphogenetic protein 15 in porcine ovarian and follicular development and ovulation

  Yufeng Qin, et al., bioRxiv - Developmental Biology 2019

  Quote: ... Smad1/5/8 (Santa cruz, sc6031R), and p-Smad2/3 (Santa cruz ...
• Identification of proximal SUMO-dependent interactors using SUMO-ID

  Orhi Barroso-Gomila, et al., bioRxiv - Biochemistry 2021

  Quote: ... 5 μg/ml blasticidin (Santa Cruz) for U2OS ...
• A transcriptional mechanism involving R-loop, m6A modification and RNA abasic sites regulates an enhancer RNA of APOE

  Jason A. Watts, et al., bioRxiv - Molecular Biology 2022

  Quote: ... 5 μg mouse IgG (Santa Cruz) NELFA (Santa Cruz) ...
• Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions

  Manuele Rebsamen, et al., bioRxiv - Cell Biology 2022

  Quote: ... SLC3A2 (Santa Cruz, 376815, E-5), tubulin (Abcam ...
• Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

  Vincenzo Torraca, et al., bioRxiv - Microbiology 2019

  Quote: ... Necrostatin-5 (10 μM, Santa Cruz) [46] ...
• Native Elongation Transcript sequencing reveals temperature dependent dynamics of nascent RNAPII transcription in Arabidopsis

  Peter Kindgren, Maxim Ivanov, Sebastian Marquardt, bioRxiv - Genomics 2019

  Quote: ... 5 μM pladienolide B (Santa Cruz) or 5 μM Herboxidiene (Focus Biomolecules ...
• Tumor-responsive, multifunctional CAR-NK cells cooperate with impaired autophagy to infiltrate and target glioblastoma

  Jiao Wang, et al., bioRxiv - Immunology 2020

  Quote: ... (5) was purchased from Santa Cruz Biotechnology ...
• ETV7 reduces inflammatory responses in breast cancer cells by repressing TNFR1/NF-κB axis

  Erna Marija Meškytė, et al., bioRxiv - Cancer Biology 2022

  Quote: ... HSP70 (C92F3A-5, Santa Cruz Biotechnologies), TEL2 (E-1 ...
• The nucleolar aberrancies that drive ribosome impairment induced by RNA binding proteins are hallmarks of aging

  Pedro Aguilar-Garrido, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p21/CIP1 (Santa Cruz, F-5), β-actin (Cell Signaling ...
• An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

  Simone Caielli, et al., bioRxiv - Immunology 2023

  Quote: ... MG132 (5 mM; Santa Cruz Biotech) was added to the culture during phase 3 ...
• Sigma receptor ligands are potent anti-prion compounds that act independently of sigma receptor binding

  Robert C. C. Mercer, et al., bioRxiv - Neuroscience 2023

  Quote: ... σ1R (B-5, Santa Cruz Biotechnology); σ2R (26444-1-AP ...
• Mitochondria directly sense osmotic stress to trigger rapid metabolic remodeling via PDH regulation

  Takeshi Ikizawa, et al., bioRxiv - Cell Biology 2022

  Quote: ... mouse monoclonal anti-PDH-E1α antibody (D-6: Santa Cruz Biotechnology, Cat#sc-377092), rat monoclonal anti-α-tubulin antibody (YL1/2 ...
• Human organoid systems reveal in vitro correlates of fitness for SARS-CoV-2 B.1.1.7

  Mart M. Lamers, et al., bioRxiv - Microbiology 2021

  Quote: ... ciliated cells were stained with anti-AcTub (1:100; Santa Cruz, 6-11B-1), club cells with anti-CC10 (1:200 ...
• An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19

  Reuben McGregor, et al., bioRxiv - Immunology 2020

  Quote: ... followed by overnight incubation in primary antibodies: anti-VDR (D-6, Santa Cruz biotechnology) pSTAT3 (D3A7 ...
• A Multiomic Analysis Reveals How Breast Cancers Disseminated to the Bone Marrow Acquire Aggressive Phenotypes through Tumor-Stroma Tunnels

  Saptarshi Sinha, et al., bioRxiv - Cancer Biology 2023

  Quote: ... We used primary antibodies against GIV (H-6, Santa Cruz Biotechnology, Dallas, TX, USA), CX43 (#3512 ...
• Dual role of CASP8AP2/FLASH in regulating epithelial-to-mesenchymal (EMT) plasticity

  Madison Catalanotto, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Actin (C-2; Santa Cruz), NPAT (sc-136007 ...
• CALR frameshift mutations in MPN patient-derived iPS cells accelerate maturation of megakaryocytes

  Kathrin Olschok, et al., bioRxiv - Cancer Biology 2021

  Quote: ... OCT3/4 (H-134, Santa Cruz, CA, USA) or mouse monoclonal antibody CAL2 (Dianova ...
• iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

  Alba Tristán-Noguero, et al., bioRxiv - Neuroscience 2022

  Quote: ... mouse anti-OCT3/4 (1:25; Santa Cruz), rabbit anti-Sox2 (1:100 ...
• Neural-specific alterations in glycosphingolipid biosynthesis and cell signaling associated with two human ganglioside GM3 Synthase Deficiency variants

  Michelle Dookwah, et al., bioRxiv - Neuroscience 2021

  Quote: ... Anti-SSEA3/4 antibody (Santa Cruz, # sc-21704), 1:200 dilution in 5% donkey serum in PBS-T ...
• Characterization of human iPSC-derived astrocytes with potential for disease modeling and drug discovery

  Vincent Soubannier, et al., bioRxiv - Neuroscience 2019

  Quote: ... goat anti-OCT3/4 (1:500; Santa Cruz Biotechnology ...
• Protein Interactome of the Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A) in Th17 Cells

  Mohd Moin Khan, et al., bioRxiv - Systems Biology 2019

  Quote: ... PP1α Antibody (G-4): (sc-271762; Santa Cruz).
• TCR signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1

  Yujiao He, et al., bioRxiv - Cell Biology 2021

  Quote: ... and RanBP2 (D-4) were from Santa Cruz Biotechnology ...
• UBC9 and EME1 sumoylation foster ribosomal DNA damage repair in CPT response

  Easa Nagamalleswari, et al., bioRxiv - Molecular Biology 2022

  Quote: ... fixed with 4% paraformaldehyde (PFA) (SC281692, Santa Cruz) in PBS for 25 minutes at room temperature before staining the cells with the respective antibodies as described above.
• Clinically-relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance

  Adriana Mañas, et al., bioRxiv - Cancer Biology 2022

  Quote: ... etoposide (4 mg/kg; Santa Cruz, sc-3512) and cyclophosphamide (75 mg/kg ...
• Generation and Maturation of Human iPSC-derived Cardiac Organoids in Long Term Culture

  Ece Ergir, et al., bioRxiv - Cell Biology 2022

  Quote: ... and fixed in 4% PFA (Santa Cruz Biotechnology) supplemented with 0.03% eosin (Sigma Aldrich ...
• Fasciola hepatica juveniles interact with the host fibrinolytic system as a potential early-stage invasion mechanism

  Judit Serrat, et al., bioRxiv - Molecular Biology 2022

  Quote: ... FhNEJ were fixed in 4% paraformaldehyde (Santa Cruz) for 1 hour at room temperature and probed with 13 μg/ml of anti-human PLG antibody raised in sheep (Innovative Research ...
• Following embryonic stem cells, their differentiated progeny, and cell-state changes during iPS reprogramming by Raman spectroscopy

  Arno Germond, et al., bioRxiv - Systems Biology 2020

  Quote: ... fixed with 4% PFA (Santa Cruz #sc-281692) for 15 min at room temperature and permeabilized with 0.5% Triton in PBS with 10% FBS addition for 30 min ...
• DRP1-mediated regulation of mitochondrial dynamics determines the apoptotic response upon embryonic differentiation

  Barbara Pernaute, et al., bioRxiv - Developmental Biology 2019

  Quote: ... anti-Oct3/4 (Santa Cruz Biotechnology, 1/1000), anti-Nanog (eBiosciences ...
• The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II at pro-differentiation genes

  Görkem Garipler, et al., bioRxiv - Developmental Biology 2020

  Quote: ... OCT3/4 (Sc-5279, Santa Cruz; 2mg/ml), GFP (ab13970 ...
• Multi-level monitoring of EME1-MUS81 in CPT induced nucleolar rDNA repair

  Karishma Bakshi, et al., bioRxiv - Molecular Biology 2022

  Quote: ... fixed with 4% paraformaldehyde (PFA) (SC281692, Santa Cruz) in PBS for 25 minutes at room temperature before staining the cells with the respective antibodies as described above ...
• Generation of Schwann cell derived melanocytes from hPSCs identifies pro-metastatic factors in melanoma

  Ryan M. Samuel, et al., bioRxiv - Developmental Biology 2023

  Quote: ... cells were fixed with 4% PFA (Santa Cruz) for 30 min at room temperature ...
• Inactivating Negative Regulators of Cortical Branched Actin Enhances Persistence of Single Cell Migration

  Artem I. Fokin, et al., bioRxiv - Cell Biology 2023

  Quote: ... p62/DCTN4 clone H-4 (Santa Cruz Biotechnology). For immunofluorescence anti-Laminin V ...
• Loss of tumor suppressor WWOX accelerates pancreatic cancer development through promotion of TGFβ/BMP2 signaling

  Hussam Husanie, et al., bioRxiv - Cancer Biology 2022

  Quote: ... polyclonal BMP2/4 (Santa Cruz; sc6267, Texas, USA), monoclonal pSMAD 2/3 (Cell Signaling ...
• ATG2A-mediated bridge-like lipid transport regulates lipid droplet accumulation

  Justin L. Korfhage, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-WIPI-4 (Santa Cruz Biotechnology; sc398272), rabbit anti-LC3B (D11 ...
• Systematic mapping and modeling of 3D enhancer-promoter interactions in early mouse embryonic lineages reveal regulatory principles that determine the levels and cell-type specificity of gene expression

  Dylan Murphy, et al., bioRxiv - Molecular Biology 2023

  Quote: ... mouse anti-Gata-4 (Santa Cruz, 1:100), rabbit anti-NANOG (Bethyl ...
• Structure and dynamics of a pentameric KCTD5/Cullin3/Gβγ E3 ubiquitin ligase complex

  Duc Minh Nguyen, et al., bioRxiv - Biochemistry 2023

  Quote: ... and anti-Gb1-4 (sc-378, Santa Cruz) antibodies respectively.
• Mitochondrial double-stranded RNAs as a pivotal mediator in the pathogenesis of Sjögren’s syndrome

  Jimin Yoon, et al., bioRxiv - Molecular Biology 2022

  Quote: ... cells were pretreated with 20 µM of 2-C′-methyladenosine (2-CM) (Santa Cruz Biotechnology) 24 h prior to poly I:C transfection.
• Bmf Facilitates Protein Degradation and Reduces Beclin1 Ubiquitination to Inhibit Autophagy Independent of mTOR

  Monica Delgado-Vergas, et al., bioRxiv - Cell Biology 2020

  Quote: ... We immunoprecipitated proteins with mouse anti Bcl-2 (C-2) (sc-7382 from Santa Cruz), rabbit anti Beclin1 (ab55878 from Abcam ...
• TRF1 poly(ADP-ribosyl)ation by PARP1 allows proper telomere replication through helicase recruitment in non-ALT cells

  C. Maresca, et al., bioRxiv - Molecular Biology 2021

  Quote: ... was immunoprecipitated (IP) overnight at 4°C with 4 μg of the anti-TRF1 antibody (goat Pab sc-1977, Santa Cruz) or the anti-WRN antibody (Rabbit Pab NB100-471 ...
• The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells

  Valentine Clerc, et al., bioRxiv - Molecular Biology 2024

  Quote: ... Chromatin was next immunoprecipitated overnight at 4°C with 4 μg of mouse anti-MYCN II antibody (sc53993, Santa Cruz Biotechnology) or an equivalent amount of the corresponding IgG Isotype control (ThermoFisher ...
• CTCF/cohesin organize the ground state of chromatin-nuclear speckle association

  Ruofan Yu, et al., bioRxiv - Genetics 2023

  Quote: Cells were washed twice with PBS and fixed with Paraformaldehyde solution 4% in PBS (Santa Cruz Biotechnology, CAS 30525-89-4) for 10 minutes at room temperature ...
• Multicellular Organoids of the Neurovascular Blood-Brain Barrier: A New Platform for Precision Neuronanomedicine

  Murali Kumarasamy, Alejandro Sosnik, bioRxiv - Bioengineering 2020

  Quote: ... claudin-5 (CLDN5, sc-374221, Santa Cruz), (v ...
• Acute perturbation of retromer and ESCPE-1 leads to functionally distinct and temporally resolved defects in endosomal cargo sorting

  Ashley J. Evans, et al., bioRxiv - Cell Biology 2019

  Quote: ... SNX6 (Clone D-5; 365965; Santa Cruz Biotechnology ...
• Type III interferons disrupt the lung epithelial barrier upon viral recognition

  Achille Broggi, et al., bioRxiv - Immunology 2020

  Quote: ... p21 (F-5) purchased from Santa Cruz. Live/dead cell markers Zombie Red™ (423109 ...
• Phosphatidylinositol 4-kinase III beta regulates cell shape, migration and Focal Adhesion number

  Patricia Bilodeau, et al., bioRxiv - Cell Biology 2020

  Quote: ... 5’-ATAAGCTCCCTGCCCGAGTC-3’ (Santa Cruz sc-430739).