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401 - 450 of 8618 citations for 4 4 Fluoro 2 hydroxyphenyl methyl 2 6 bis 1 methylethyl 5 propyl 3 pyridinemethanol since 2020

• MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

  Célia Guérin, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ERK1/2 (Santa Cruz #Sc-154), ERK1/2-Phospho (Cell Signaling #9101) ...
• Lactational delivery of Triclosan promotes non-alcoholic fatty liver disease in newborn mice

  André A. Weber, et al., bioRxiv - Pharmacology and Toxicology 2022

  Quote: ... AMPKα1/2 (Santa Cruz, sc-25792), CYP7A1 (Abcam ...
• Capture of Human Neuromesodermal and Posterior Neural Tube Axial Stem Cells

  Dolunay Kelle, et al., bioRxiv - Developmental Biology 2024

  Quote: ... and 2 µM IWP2 (Santa Cruz). The cells were split using 1X TrypLE Express at a ratio of 1:20-1:40.
• A common druggable signature of oncogenic CMYC, mutant KRAS and mutant p53 reveals functional redundancy and competition of the oncogenes in cancer

  Maria Grześ, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Gli-2 (Santa Cruz sc-271786); c-Jun (Santa Cruz sc-74543) ...
• GSE1 links the HDAC1/CoREST co-repressor complex to DNA damage

  Terezia Vcelkova, et al., bioRxiv - Molecular Biology 2023

  Quote: ... 2 μg GSE1 (515046, Santa Cruz), 30 μl of monoclonal HDAC1 (clone 10E2 ...
• Down-regulation of AKT proteins slows the growth of mutant-KRAS pancreatic tumors

  Chuankai Chen, et al., bioRxiv - Cancer Biology 2024

  Quote: ... ERK1/2 (Santa Cruz, sc-514302).
• Control of intestinal stemness and cell lineage by histone variant H2A.Z isoforms

  Jérémie Rispal, et al., bioRxiv - Physiology 2024

  Quote: ... Mucin 2 (sc-15334, Santa Cruz), Lysosyme (ab108508 ...
• c-Abl Kinase Targets Tight Junction Protein ZO-2 in Regulation of Cell Migration and Morphology

  Doo Eun Choi, et al., bioRxiv - Cell Biology 2024

  Quote: ... ZO-2 polyclonal antibody (Santa Cruz), phospho-tyrosine monoclonal antibody (4G10 ...
• Evolutionary origins and innovations sculpting the mammalian PRPS enzyme complex

  Bibek R. Karki, et al., bioRxiv - Biochemistry 2024

  Quote: ... PRPS1/2 (Santa Cruz #sc-100822), PRPS1 (Proteintech #15549-1-AP) ...
• Production of Hyaluronan by the Trophectoderm is a Prerequisite for Mouse Blastocyst Attachment

  Ron Hadas, et al., bioRxiv - Developmental Biology 2020

  Quote: ... mouse anti TLR-4 (sc-293072; Santa Cruz Biotechnology), goat anti GFP (ab6673 ...
• MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

  Xintao Qiu, et al., bioRxiv - Genomics 2021

  Quote: ... RNA Pol II (4 μg, #sc899, Santa Cruz Biotechnology) or H3K27ac (10 μl ...
• Hyaluronan and Elastin-Like Protein (HELP) Gels Significantly Improve Cargo Retention in the Myocardium

  Riley A. Suhar, et al., bioRxiv - Bioengineering 2021

  Quote: ... dissolve enough 4-azidobenzaldehyde (Santa Cruz Biotechnology, sc-503201) for HA-B or Ald- CH2-PEG3-Azide (BroadPharm ...
• Inhibition of major histocompatibility complex-I antigen presentation by sarbecovirus ORF7a proteins

  Fengwen Zhang, et al., bioRxiv - Microbiology 2022

  Quote: ... Cells were fixed with 4% paraformaldehyde (Santa Cruz Biotechnology) and subsequently permeabilized with Perm/Wash Buffer (BD Biosciences) ...
• Imperfect innate immune antagonism renders SARS-CoV-2 vulnerable towards IFN-γ and -λ

  Manuel Hayn, et al., bioRxiv - Microbiology 2020

  Quote: ... followed by fixation in 4% Paraformaldehyde (Santa Cruz Biotechnology). The fluorescence intensity of membrane associated GFP-LC3B was then quantified via flow cytometry (FACSCanto II ...
• Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication

  Helene Borrmann, et al., bioRxiv - Microbiology 2020

  Quote: ... Cells were fixed with 4% PFA (Santa Cruz, UK) for 10 min at room temperature ...
• Phosphorylation of STIM1 at ERK/CDK sites is dispensable for cell migration and ER partitioning in mitosis

  Ayat S. Hammad, et al., bioRxiv - Cell Biology 2021

  Quote: ... EB1 (1A11/4) mouse monoclonal (Santa Cruz #sc-47704) and β-actin (C4 ...
• LTK and ALK regulate neuronal polarity and cortical migration by modulating IGF1R activity

  Tania Christova, et al., bioRxiv - Neuroscience 2023

  Quote: ... PPP (CAS 477-47-4, Santa Cruz, scbt #24008) and recombinant murine IGF-1 (Peprotech).
• Host cell glycosylation selects for infection with CCR5- versus CXCR4-tropic HIV-1

  Hannah L. Itell, et al., bioRxiv - Microbiology 2023

  Quote: ... fixed in 4% paraformaldehyde (Santa Cruz Biotechnology #sc-281692) for 10 min ...
• Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level

  Birthe Dorgau, et al., bioRxiv - Developmental Biology 2023

  Quote: ... After fixation using 4% paraformaldehyde (PFA; Santa Cruz Biotechnologies) organoids were cryopreserved ...
• KAT6A mutations drive transcriptional dysregulation of cell cycle and Autism risk genes in an Arboleda-Tham Syndrome cerebral organoid model

  Aileen A. Nava, et al., bioRxiv - Genetics 2023

  Quote: ... and a mouse anti-OCT3/4 (Santa Cruz #SC5279) antibody using a 1/200 dilution for each ...
• Enterovirus A71 adaptation to heparan sulfate comes with capsid stability tradeoff

  Han Kang Tee, et al., bioRxiv - Microbiology 2024

  Quote: ... infected cells were fixed with 4% paraformaldehyde (Santa Cruz) and incubated with blocking buffer ...
• Herpes Simplex Virus-1 targets the 2’-3’cGAMP importer SLC19A1 as an antiviral countermeasure

  Zsuzsa K. Szemere, Eain A. Murphy, bioRxiv - Microbiology 2024

  Quote: ... and SLC19A1 PE antibody (D-4 clone, Santa Cruz) for 15 minutes at room temperature ...
• NEK1 haploinsufficiency worsens DNA damage but not defective ciliogenesis in C9ORF72 patient-derived iPSC-motoneurons

  Serena Santangelo, et al., bioRxiv - Neuroscience 2024

  Quote: ... cells were fixed in 4% paraformaldehyde (Santa Cruz Biotechnology) for 20 minutes and permeabilized with ice-cold methanol and with 0.3% Triton X-100 for 5 minutes each ...
• Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington’s Disease

  Christina Pressl, et al., bioRxiv - Neuroscience 2023

  Quote: ... Transducin Like Enhancer Of Split 4 (TLE4, Santa Cruz Biotechnology Cat# sc-365406 ...
• Specialized actin nanoscale layers control focal adhesion turnover

  Reena Kumari, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-EB1 (1A11/4; Santa Cruz, 47704), rabbit anti-KANK1 (Bethyl laboratories ...
• Plasma membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ankh) mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing

  Emma Naomi James, et al., bioRxiv - Cell Biology 2024

  Quote: ... Actin C-4 (mouse Santa Cruz cat# sc-47778), ASCT2 (rabbit Cell Signaling cat# 5345).
• Post-transcriptional regulation of insulin mRNA storage by G3BP1/2⁺ condensates in beta cells

  Esteban Quezada, et al., bioRxiv - Molecular Biology 2024

  Quote: ... were fixed with 4% PFA (Santa Cruz, sc-281692) for 20 minutes under the chemical hood ...
• Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance

  Xue Chen, Deng Pan, Jia-Jia Liu, Yanrui Yang, bioRxiv - Neuroscience 2024

  Quote: ... mouse anti-SYP (D-4) (sc-17750, Santa Cruz), rabbit anti-FLAG (F3165 ...
• Proteome biology of primary colorectal carcinoma and corresponding liver metastases

  Matthias Fahrner, et al., bioRxiv - Cancer Biology 2021

  Quote: ... cells were incubated for 48 h after adding 5 mM (final conc.) of N-methyl-DL-aspartic acid (MDLA) (Santa Cruz), solved in water ...
• SUMO Modifies GβL and Mediates mTOR Signaling

  Sophia Louise Lucille Park, et al., bioRxiv - Biochemistry 2020

  Quote: ... GβL (sc-425272) and SUMO1/2/3 deletion were carried out in striatal cells using CRISPR/Cas-9 tools obtained from Santa Cruz, as described before [46 ...
• Endoplasmic Reticulum Associated Degradation (ERAD) Deficiency Promotes Mitochondrial Dysfunction and Transcriptional Rewiring in Human Hepatic Cells

  Xiaoqing Yang, et al., bioRxiv - Cell Biology 2020

  Quote: ... membranes were incubated at 4°C overnight with primary antibodies aginst: p-JNK (Santa Cruz, 1:800), Caspase-1 (Santa Cruz ...
• PAT2 regulates autophagy through vATPase assembly and lysosomal acidification in brown adipocytes

  Jiefu Wang, et al., bioRxiv - Cell Biology 2020

  Quote: ... Particles corresponding to 4 µg protein were added with or without 1 µM concanamycin A (Santa Cruz) to flat glass bottom plates to measure FITC fluorescence at 488 nm at 37°C ...
• Short-Duration RAGE Antagonism Transiently Disrupts Tendon Homeostasis and does not Alter Diabetic Tendon Healing

  Anne E. C. Nichols, et al., bioRxiv - Pathology 2021

  Quote: ... Membranes were probed overnight at 4°C with antibodies to RAGE (1:1000; Santa Cruz #sc-365154), phospho-p65 (1:1000 ...
• Hsp27 reduces glycation-induced toxicity and aggregation of α-synuclein

  Hugo Vicente Miranda, et al., bioRxiv - Neuroscience 2020

  Quote: ... Hsp27 levels were probed with anti-Hsp27 (F-4 1:2000; Santa Cruz Biotechnology, Dallas, TX, USA). Detection procedures were performed according to ECL system (GE Healthcare ...
• Facilitating mGluR4 activity reverses the long-term deleterious consequences of chronic morphine exposure

  Jerome AJ Becker, et al., bioRxiv - Neuroscience 2020

  Quote: ... from Cell Signaling Technology and synaptophysin (mouse SYP antibody [D-4], ref. sc-17750; RRID: AB_628311) (1:2000) from Santa Cruz Biotechnology were used at the indicated dilutions ...
• HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesis

  Kentaro Akagi, et al., bioRxiv - Cell Biology 2023

  Quote: ... and fixed cells were stained with mouse anti-Oct3/4 (1:50, Santa Cruz Biotechnology, Cat.# sc5279) and anti-TRA1-81 (1:100 ...
• Huntingtin expression influences spontaneous seizure disorder susceptibility in FVN/B mice

  Jeremy M. Van Raamsdonk, et al., bioRxiv - Neuroscience 2022

  Quote: ... CA) or rabbit polyclonal anti-BDNF antibody (1:1000, overnight, 4 °C; Santa Cruz, Santa Cruz, CA).
• Huntingtin expression influences spontaneous seizure disorder susceptibility in FVN/B mice

  Jeremy M. Van Raamsdonk, et al., bioRxiv - Neuroscience 2022

  Quote: ... CA) or rabbit polyclonal anti-BDNF antibody (1:1000, overnight, 4 °C; Santa Cruz, Santa Cruz, CA).
• Lack of mTORC2 signaling in CD11c⁺ myeloid cells inhibits their migration and ameliorates experimental colitis

  Aline Ignacio, et al., bioRxiv - Immunology 2023

  Quote: ... or incubated overnight at 4 °C using a polyclonal anti-Cdc42 antibody (1:500, Santa Cruz Biotechnology). The membranes were incubated with the fluorescent secondary antibodies IRDye 680CW or IRDye 800CW for 1 h and visualized using the Odyssey Infrared Image System (CLx model ...
• Reproducible differentiation of pure ovarian support cells from clinical-grade hiPSCs as a novel infertility treatment

  Bruna Paulsen, et al., bioRxiv - Bioengineering 2024

  Quote: ... The primary antibodies used were mouse monoclonal antibody against OCT3/4 (1:200; sc5279, Santa Cruz Biotechnology), goat polyclonal antibody against SOX2 (1:50 ...
• Putative EGF ligand and receptor of Echinococcus multilocularis that are critical for parasite development

  Akito Koike, et al., bioRxiv - Microbiology 2024

  Quote: ... and incubated overnight at 4°C with antibodies raised against phosphotyrosine PY20 (Santa Cruz Biotechnology, 1/1200), before treatment with a ready-to-use stripping buffer (Clinisciences ...
• Stimulus-specific processing of the plasma membrane receptor-like kinase FERONIA in Arabidopsis thaliana

  Cassidy S. Cornblatt, et al., bioRxiv - Plant Biology 2021

  Quote: ... Antibody dilutions used were 1:500 for α-GFP (B-2, Santa Cruz Biotechnology), 1:2500 for α-calnexin (CNX1/2 ...
• Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition

  Golam T. Saffi, et al., bioRxiv - Cell Biology 2021

  Quote: ... and goat polyclonal antibody against dynamin 2 (1:1000, sc-6400, Santa Cruz Biotechnology). Secondary antibodies were raised in donkey (Bethyl ...
• Novel regulation of the transcription factor ZHX2 by N-terminal methylation

  Meghan M. Conner, et al., bioRxiv - Biochemistry 2021

  Quote: ... mouse anti-ZHX2 (D-2) (1:1000; sc-393399, Santa Cruz Antibodies, Dallas, TX), rabbit anti-CYP26A1 (1:1000 ...
• H₂S Prodrug, SG-1002, Protects Against Myocardial Oxidative Damage and Hypertrophy via Induction of Cystathionine β-Synthase and Antioxidant Proteins

  Rahib K. Islam, et al., bioRxiv - Cell Biology 2021

  Quote: The polyclonal antibody for GPx-1/2 (sc-30147) was purchased from Santa Cruz Biotechnology ...
• Regulation of Oocyte Meiotic Maturation: Unraveling the Interplay between PKA Inhibition and Cdk1 Activation

  Martina Santoni, et al., bioRxiv - Cell Biology 2023

  Quote: ... Erk1/2 (1:2000 each, rabbit, Santa Cruz Biotechnology C-16 and C-14), pT320-pp1 (1:1000 for the detection of the endogenous protein ...
• MYCN driven oncogenesis involves cooperation with WDR5 to activate canonical MYC targets and G9a to repress differentiation genes

  Zhihui Liu, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Two different MYCN antibodies (antibody 1, Santa Cruz, sc-53993; antibody 2, Abcam, ab16898) (4 µg) ...
• The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

  Ke Xu, et al., bioRxiv - Developmental Biology 2022

  Quote: ... mouse anti-LIMK-2 monoclonal antibody (1:100 dilution, sc-365414, Santa Cruz Biotechnology), mouse anti-F-actin monoclonal antibody (1:500 dilution ...
• CCDC32 stabilizes clathrin-coated pits and drives their invagination

  Ziyan Yang, et al., bioRxiv - Cell Biology 2024

  Quote: ... Anti-α-Adaptin 1/2 Antibody (C-8) (Santa Cruz Biotechnology, Catalog #sc-17771) was used in WB to detect AP2 enrichments.
• Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension

  Monika Lakk, et al., bioRxiv - Cell Biology 2021

  Quote: ... The samples were incubated overnight at 4 °C with TRPV4 (1:500, Alomone Labs) and flotillin (1:200, Santa Cruz Biotechnology) antibodies ...