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4101 - 4150 of 8287 citations for 6 Phenyl 1H imidazo 1 2 b pyrazole since 2019

• Tau alters global gene expression affecting chromatin in the early stages of Alzheimer’s disease

  G. Siano, et al., bioRxiv - Neuroscience 2023

  Quote: ... HRP-conjugated anti-mouse 1:1000 (Santa Cruz Biotechnology), and HRP-conjugated anti-rabbit 1:1000 (Santa Cruz Biotechnology) ...
• A simple and reliable method for claustrum localization across age in mice

  Tarek Shaker, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse anti-Tle4 (sc365406, Santa Cruz Biotechnology; 1:250), goat anti-PV (PVG213 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CHMP7 (sc-271805, 1:30, Santa Cruz Biotechnology) and anti-TSG101 antibody (ab133586 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CHMP7 (sc-271805, 1:1000, Santa Cruz Biotechnology) and anti-TSG101 antibody (ab133586 ...
• Nuclear NFκB Activity Balances Purine Metabolism in Cellular Senescence

  Sho Tabata, et al., bioRxiv - Systems Biology 2023

  Quote: ... HPRT1 (1:500; Santa Cruz Biotechnology, Inc., sc-376938), Cyclin D1 (1:1000 ...
• Interaction with IP6K1 supports pyrophosphorylation of substrate proteins by the inositol pyrophosphate 5-IP7

  Aisha Hamid, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-UBF1 (Santa Cruz, sc-13125 IB, 1:500). For immunoprecipitation of endogenous IP6K1 ...
• Inhibiting Stromal Class I HDACs Curbs Pancreatic Cancer Progression

  Gaoyang Liang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and mouse IgG (Santa Cruz, sc-2005, 1:5000). Chemiluminescent reaction was performed with SuperSignal West Dura substrate (Thermo ...
• MIF Regulates M1 Macrophage Polarization via CD74/CXCR2/JNK Pathway and Mediates Aortic Dissection in Mice

  Lu Wang, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-p-JNK (1:200, sc-6254, Santa Cruz), anti-JNK (1:200 ...
• Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice

  David V.C. Brito, et al., bioRxiv - Neuroscience 2023

  Quote: ... and β-Actin (1:1000, Santa Cruz, #SC-47778). Antibodies were diluted in 5% milk in PBS-T ...
• Dopamine-iron homeostasis interaction rescues mitochondrial fitness in Parkinson’s disease

  Chiara Buoso, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-PGC-1α (H300) (1:1,000, Santa Cruz Biotechnology ...
• LRRK2 regulates synaptic function through BDNF signaling and actin cytoskeleton

  Giulia Tombesi, et al., bioRxiv - Neuroscience 2023

  Quote: ... rabbit α-MAP2 (sc-20172, Santa Cruz, 1:200); mouse α-drebrin (MA1-20377 ...
• CCR2-targeting pepducins reduce T cell-nociceptor interaction driving bone cancer pain

  Élora Midavaine, et al., bioRxiv - Neuroscience 2023

  Quote: ... hamster anti-CD3 (1:500, Santa Cruz, #sc-1174) in blocking buffer for three days at 37°C for spinal cord ...
• Injury induced renal fibrosis promotes cystogenesis and cyst growth in adult mice with autosomal dominant polycystic kidney disease

  Ming Wu, et al., bioRxiv - Pathology 2023

  Quote: ... anti-N-cadherin (1:1000, sc-59887, Santa Cruz), anti-vimentin (1:1000 ...
• Early nuclear phenotypes and reactive transformation in human iPSC-derived astrocytes from ALS patients with SOD1 mutations

  Vincent Soubannier, et al., bioRxiv - Neuroscience 2023

  Quote: ... or goat anti-OCT3/4 (1/500; Santa Cruz Biotechnology ...
• Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury

  Yiqun Wang, et al., bioRxiv - Neuroscience 2023

  Quote: anti-ATF3 (rabbit, 1:300, Santa Cruz sc-188),
• Aryl hydrocarbon receptor restricts axon regeneration of DRG neurons in response to injury

  Yiqun Wang, et al., bioRxiv - Neuroscience 2023

  Quote: anti-ATF3 (rabbit, 1:1,000, Santa Cruz sc-188),
• A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification

  Patricia R. Nano, et al., bioRxiv - Developmental Biology 2023

  Quote: ... SOX2 (1:500, Cat. # sc-365823, Santa Cruz Biotechnology), and VSNL1 (1:100 ...
• PPARγ controls ESCRT-dependent fibroblast-like synoviocyte exosome biogenesis and Alleviates Chondrocyte Osteoarthritis Mediated by Exosomal ANXA1

  Shuangshuo Jia, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Hrs (sc-271455, 1:30, Santa Cruz Biotechnology), STAM1 Antibody (13053 ...
• Low exposure to lithium does not induce nephrogenic diabetes insipidus but microcystic dilations of collecting ducts in a long-term rat model

  Nahid Tabibzadeh, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... 1/500 (Santa Cruz, Biotechnology Inc., Dallas, Tx, USA) and rabbit anti-AE1 20112 ...
• Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations

  Elizabeth A Forrester, et al., bioRxiv - Physiology 2023

  Quote: ... mouse anti-SGLT2 (sc-393350, 1:200, Santa Cruz), rabbit anti-smooth muscle Myosin heavy chain 11 (ab125884 ...
• Glucocerebrosidase deficiency leads to neuropathology via cellular immune activation

  Evelyn S. Vincow, et al., bioRxiv - Genetics 2023

  Quote: ... 1:500 mouse anti-ubiquitin (Santa Cruz, sc-8017), 1:2000 mouse anti-HA (BioLegend) ...
• A Meta-Atlas of the Developing Human Cortex Identifies Modules Driving Cell Subtype Specification

  Patricia R. Nano, et al., bioRxiv - Developmental Biology 2023

  Quote: ... ZBTB16/PLZF (1:250, sc-28319, Santa Cruz Biotechnology), VGAT (1:1000 ...
• Natural variation in the zinc-finger-encoding exon of Prdm9 affects hybrid sterility phenotypes in mice

  Khawla FN AbuAlia, et al., bioRxiv - Genetics 2023

  Quote: ... SYCP3 (mouse monoclonal antibody, Santa Cruz, #74569, 1:50), yH2AX (ab2893 ...
• Dectin-1 ligands produce distinct training phenotypes in human monocytes through differential activation of signaling networks

  Quen J. Cheng, et al., bioRxiv - Immunology 2023

  Quote: ... p65(RelA) (Rabbit IgG, 1:1000, Santa Cruz 372), p-STAT1 (Rabbit IgG ...
• The RNA binding protein, HNRNPA2B1, regulates IFNG signaling in macrophages

  Mays Mohammed Salih, et al., bioRxiv - Immunology 2023

  Quote: ... or GAPDH (1:1000, Santa Cruz Biotech, Sc-32233) were used as loading controls ...
• Chlamydial protease-like activating factor targets SLC7A11 for degradation to induce ferroptosis and facilitate dissemination

  Wentao Chen, et al., bioRxiv - Microbiology 2023

  Quote: ... TfR1(1:500, Santa Cruz Biotechnology Cat# sc-32272), Vimentin (1:1000 ...
• Identification of a P62-TIF-IA axis that drives nucleolar fusion and the senescence associated secretory phenotype

  Hazel C Thoms, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Actin-HRP (Mouse 1:2000 sc-47778 Santa Cruz). Bands were quantified using ImageJ as per software instructions.
• Torques within and outside the human spindle balance twist at anaphase

  Lila Neahring, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-MKLP1 C-12 (1:50, Santa Cruz Biotechnology sc-390113 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Arp2 (1:1000; Santa Cruz; sc-166103), mouse anti-Arp3 (1:1000 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-WIP1 (1:1000, Santa Cruz; sc-271113), rabbit anti-WIP2 (1:1000 ...
• Molecular Regulation of Invasive Protrusion Formation at the Mammalian Fusogenic Synapse

  Yue Lu, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse anti-Arp3 (1:1000; Santa Cruz; sc-48344), mouse anti-MyoG (1:30 ...
• The 21-base pair deletion mutant Calpain 3 does not inhibit wild-type Calpain 3 activity

  Swati Maitra, et al., bioRxiv - Cell Biology 2023

  Quote: ... Calpain 3 (Proteintech and Santa Cruz Biotechnology, 1:1000), Calpastatin (Proteintech and Santa Cruz Biotechnology ...
• Analyzing ER stress response in ALS patient derived motor neurons identifies druggable neuroprotective targets

  Michelle E. Watts, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-Chx10 (Santa Cruz Biotechnology sc-365519, 1:50), and anti-TUJ1 (Biolegend 801202 ...
• A novel iPSC model reveals selective vulnerability of neurons in Multiple Sulfatase Deficiency

  Vi Pham, et al., bioRxiv - Cell Biology 2023

  Quote: ... IgM isotype control (1:100, Santa Cruz, sc-3881). Cells were subsequently washed with saponin buffer or FACS buffer and incubated for 1 hr with secondary antibodies ...
• Revisiting the potency of Tbx2 expression in transforming outer hair cells into inner hair cells at multiple ages in vivo

  Zhenghong Bi, et al., bioRxiv - Developmental Biology 2023

  Quote: ... anti-Prestin (goat, 1:1000; sc-22692, Santa Cruz), anti-vGlut3 (rabbit ...
• Targetable leukemia dependency on noncanonical PI3Kγ signaling

  Qingyu Luo, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-PIK3CG (1:500; sc-166365; Santa Cruz Biotechnology), anti-ubiquitin (1:1000 ...
• CRISPR Screening in Tandem with Targeted mtDNA Damage Reveals WRNIP1 Essentiality

  Tanja Sack, et al., bioRxiv - Biochemistry 2023

  Quote: ... 1:1000 and anti-WRNIP1 (Santa Cruz, sc-377402). The cells were stained with MitoTracker Deep Red (200 nM ...
• Tubular obstruction induced polycystin upregulation is pro-fibrotic and induced a severe cystic phenotype in adult mice with autosomal dominant polycystic kidney disease: the coexistence of polycystin loss and gain function in ADPKD

  Ming Wu, et al., bioRxiv - Pathology 2023

  Quote: ... anti-N-cadherin (1:1000, sc-59887, Santa Cruz), anti-vimentin (1:1000 ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GFP (Santa Cruz Bio cat.no. sc-9996, 1:1,000). The following secondary antibodies were used ...
• Harnessing DNA replication stress to target RBM10 deficiency in lung adenocarcinoma

  Feras E. Machour, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Rad51 (Santa Cruz Bio cat.no. sc-8349, 1:1,000), PARP1 (Enzo Life Sciences cat ...
• Selective Vulnerability of Layer 5a Corticostriatal Neurons in Huntington’s Disease

  Christina Pressl, et al., bioRxiv - Neuroscience 2023

  Quote: ... Solute Carrier Family 1 Member 3 (SLC1A3, Santa Cruz sc-515839 used at a concentration of 1:2000) ...
• The NAD⁺ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers’ Disease

  Yu Hong, et al., bioRxiv - Neuroscience 2023

  Quote: ... Nestin (1:50, Santa Cruz Biotechnology, cat. no. sc23927), NeuN (1:500 ...
• Long-chain fatty acyl-coenzyme A activates the mitochondrial fission factors MiD49 and MiD51 by inducing their oligomerization

  Ao Liu, et al., bioRxiv - Cell Biology 2023

  Quote: ... GAPDH (G-9, mouse; Santa Cruz Biotechnology; 1:500), actin (mouse ...
• Amyloid β induces cardiac dysfunction and neuro-signaling impairment in the heart of an Alzheimer’s disease model

  Andrea Elia, et al., bioRxiv - Molecular Biology 2023

  Quote: ... and GAPDH (sc-32233,6C5; Santa Cruz Biotechnology; 1: 2000), the latter which was used as the loading control ...
• Influenza A virus NS1 effector domain is required for PA-X mediated host shutoff

  Juliette Bougon, et al., bioRxiv - Microbiology 2023

  Quote: ... NP (IAV) (1:1000, mouse, Santa Cruz, sc-101352), NP (IBV ...
• Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and function

  Bryan Alava, et al., bioRxiv - Neuroscience 2023

  Quote: ... Tau46 (Santa Cruz Biotechnology Inc. sc-32274; 1:1000), or AT8 primary antibody (Thermo Fisher Scientific MN1020 ...
• Collagen fibril formation at the plasma membrane occurs independently from collagen secretion

  Adam Pickard, et al., bioRxiv - Cell Biology 2024

  Quote: ... Syntaxin 5 (Santa Cruz, sc-365124, 1:500(WB)) PDI (Abcam ...
• Homologous recombination promotes mitotic death to suppress the innate immune response

  Radoslaw Szmyd, et al., bioRxiv - Cell Biology 2024

  Quote: ... WAPL (A-7, Santa Cruz, sc-365189, 1:1000), CHK1 (2G1D5 ...
• Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth

  Hitoshi Matakatsu, Richard G. Fehon, bioRxiv - Developmental Biology 2024

  Quote: ... Rabbit anti-HA (1:1,000; Y-11, Santa Cruz), iFluor 555 or iFluor 647 conjugated Mouse anti-V5 (1:100 ...
• Control of epiblast cell fate by mechanical cues

  Charlène Guillot, et al., bioRxiv - Developmental Biology 2024

  Quote: ... PHOSPHO-HISTONE 3 (1/1000, SANTA CRUZ: sc-8656), MSGN1 (1/1000)55 ...