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3901 - 3950 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration

  Marta Marzullo, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-HA HRP (1:1000; Santa Cruz sc7392); anti-Su(var)3-9 rat (1:50 ...
• PD1 is transcriptionally regulated by LEF1 in mature T cells

  Pin Zhao, Lanming Sun, Cong Zhao, Samiullah Malik, bioRxiv - Immunology 2023

  Quote: ... β-actin (Dilution of 1:2000, E0919, Santa Cruz); PD1 (Dilution of 1:2500 ...
• PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription

  Isabel Mayayo-Peralta, et al., bioRxiv - Genomics 2022

  Quote: ... HSP90 (sc-13119, Santa Cruz Biotechnologies, 1:1000), P27 (610242,BD Biosciences ...
• Curcumin combined with verapamil improve cardiovascular phenotype of a Williams-Beuren Syndrome mice model reducing oxidative stress

  Noura Abdalla, et al., bioRxiv - Genetics 2022

  Quote: ... anti-NRF2 (1:500 Santa Cruz sc-H300) and pNRF2 (1:5000 ...
• Transsynaptic labeling and transcriptional control of zebrafish neural circuits

  Cagney Coomer, et al., bioRxiv - Neuroscience 2023

  Quote: ... PKCa (Santa Cruz Biotechnologies, sc-17769, 1:100) and zpr-3 (ZIRC ...
• Caloric restriction prevents inflammation and insulin dysfunction in middle-aged ovariectomized mice

  Leticia Roberta Leme Sapatini, et al., bioRxiv - Physiology 2023

  Quote: ... and IR (Santa Cruz, Dallas, USA; 1:250), and SIRT1 ...
• Noncanonical Rab9a action supports endosomal exit of human papillomavirus during virus entry

  Jeongjoon Choi, Daniel DiMaio, bioRxiv - Microbiology 2023

  Quote: ... or GST (Santa Cruz, sc-138, 1:2,000). Secondary horseradish peroxidase (HRP)-conjugated antisera recognizing rabbit or mouse antibodies as appropriate (Jackson ImmunoResearch ...
• Dynamic Effects of Ventral Hippocampal NRG3/ERBB4 Signaling on Nicotine Withdrawal-Induced Responses

  Miranda L. Fisher, et al., bioRxiv - Neuroscience 2023

  Quote: ... ERBB4 (1:500, sc-283, Santa Cruz Biotechnology), and Beta-tubulin (1:2000 ...
• Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting the oxysterol-binding protein OSBP

  Marko Cigler, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... GAPDH (1:5,000; Santa Cruz Biotechnology, sc-365062), GOLIM4 (1:1,000 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... γH2AX (Santa Cruz sc-517348; 1:200 IF), 53BP1 (Novus NB100-304 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: GAPDH (Santa Cruz sc-47724; 1:5000 WB), α-tubulin (Millipore 05-829 ...
• OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

  Mariarosaria De Rosa, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p53 (Santa Cruz sc-126; 1:200 WB), p21 (Cell Signaling 2947 ...
• Reversal of cell, circuit and seizure phenotypes in a mouse model of DNM1 epileptic encephalopathy

  K. Bonnycastle, et al., bioRxiv - Neuroscience 2023

  Quote: ... goat anti-dynamin-1 (Santa Cruz sc-6402) 1:200) ...
• Proteostasis and lysosomal quality control deficits in Alzheimer’s disease neurons

  Ching-Chieh Chou, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CHMP6 (1:200; Santa Cruz, sc-398963), anti-Galectin-3 (1:1000 ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... Ubiquitin (sc-8017, Santa Cruz, mouse, 1:1000); p97 (MA3-004 ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GST (sc-138, Santa Cruz, mouse, 1:1000); p47 (NBP213677 ...
• Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

  Natalia Pardo-Lorente, et al., bioRxiv - Cell Biology 2023

  Quote: ... KIF4A (Santa Cruz Biotechnology; #sc-365144; 1:1000), PRMT1 (Santa Cruz Biotechnology ...
• Apparent RNA bridging between PRC2 and chromatin is an artefact of non-specific chromatin precipitation upon RNA degradation

  Alex Hall Hickman, Richard G. Jenner, bioRxiv - Molecular Biology 2023

  Quote: ... anti-SUZ12 (1:1000; Santa Cruz, sc-271325), anti-Beta-Tubulin (1:1000 ...
• Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity

  Melica Nourmoussavi Brodeur, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and vinculin (sc-73614, Santa Cruz; 1:5000) were used as reference protein ...
• Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

  Priyanka Gupta, et al., bioRxiv - Cancer Biology 2023

  Quote: ... RBL1 (Santa Cruz sc-318; RRID:AB_2175428; 1:500), P-S391 SUV39H1 (Bibb Lab ...
• DNA methylation insulates genic regions from CTCF loops near nuclear speckles

  Shelby A. Roseman, et al., bioRxiv - Genomics 2023

  Quote: ... GAPDH (1:2000, Santa Cruz Biotechnology sc-47724); Vinculin (1:2000 ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... rabbit anti-GFP (1:1000; FL Santa Cruz), rabbit anti-l-Afadin (1:500 ...
• Faulty Metabolism: A Potential Instigator of an Aggressive Phenotype in Cdk5-dependent Medullary Thyroid Carcinoma

  Priyanka Gupta, et al., bioRxiv - Cancer Biology 2023

  Quote: ... H1.5 (Santa Cruz sc-247158; RRID:AB_10847577; 1:1000), P-S988 RBL1 (Bibb Lab ...
• A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator

  Anniek Zaalberg, et al., bioRxiv - Cancer Biology 2023

  Quote: ... HSP90 (sc-12119, Santa Cruz Biotechnologies, 1:1000) diluted in 4% BSA/PBS-T ...
• Targeting Ovarian Cancer Stem Cells by Dual Inhibition of the Long Noncoding RNA HOTAIR and Lysine Methyltransferase EZH2

  Weini Wang, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Staining with p65 antibody (1:500, Santa Cruz) was followed by Alexa fluor-568 anti-mouse antibody (1:1000 ...
• Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

  Yevgeniy V. Serebrenik, et al., bioRxiv - Cell Biology 2023

  Quote: ... GFP (sc-9996, Santa Cruz Biotechnology; 1:1666), alpha-tubulin (NB100-690 ...
• Regulation of Oocyte Meiotic Maturation: Unraveling the Interplay between PKA Inhibition and Cdk1 Activation

  Martina Santoni, et al., bioRxiv - Cell Biology 2023

  Quote: ... Karyopherin (1:2000, goat, Santa Cruz sc-1863), CPEB1 (1:2000 ...
• Weak neuronal glycolysis sustains cognition and organismal fitness

  Daniel Jimenez-Blasco, et al., bioRxiv - Cell Biology 2023

  Quote: ... 1/500 anti-Rock2 (sc398519; Santa Cruz Biotechnology) in in 0.2 % Triton X-100 (Sigma-Aldrich ...
• Nuclear MTHFD2 secures mitosis progression by preserving centromere integrity

  Natalia Pardo-Lorente, et al., bioRxiv - Cell Biology 2023

  Quote: ... TPR (Santa Cruz Biotechnology; #sc-101294; 1:1000), KIF4A (Santa Cruz Biotechnology ...
• Illuminating the Terminal Nerve: Uncovering the Link between GnRH-1 and Olfactory Development

  Enrico Amato Jr, et al., bioRxiv - Developmental Biology 2023

  Quote: ... mouse-α-Calb1 (1:200, Santa Cruz Biotechnology), goat-α-Nqo1 (1:700 ...
• Histone lactylation antagonizes senescence and skeletal muscle aging via facilitating gene expression reprogramming

  Xuebin Zhang, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-p21 (Santa Cruz Biotechnology, sc397, 1:500), anti-β-ACTIN (Santa Cruz Biotechnology ...
• Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes

  Laurent Starck, et al., bioRxiv - Neuroscience 2023

  Quote: ... and Fibronectin (Santa Cruz Biotechnology, 1:200 dilution). Primary antibody was incubated overnight at 4°C ...
• Biophysical basis for the induction of glioblastoma-like phenotype in astrocytes

  Laurent Starck, et al., bioRxiv - Neuroscience 2023

  Quote: ... and GAPDH (Santa Cruz Biotechnology, 1:500 dilution). Primary antibodies were incubated overnight in 2.5% BSA in TBST ...
• The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria and tyrosinemia type 1

  Peter D. Szigetvari, et al., bioRxiv - Molecular Biology 2023

  Quote: ... GAPDH (#sc-32233 Santa Cruz Biotech; 1:1000) primary antibodies and proteins were detected by incubation at a 1:5000 dilution with secondary horseradish peroxidase (HRP)- conjugated antibodies (#170-6516 ...
• The Role of Respiratory Complex IV in Lifespan Length and Quality

  Beatriz Castejon-Vega, et al., bioRxiv - Molecular Biology 2023

  Quote: ... p70 S6K (Santa Cruz, sc-230, 1:1,000); phospho-p70 S6K (Cell Signalling ...
• MicroRNA-375 is induced during astrocyte-to-neuron reprogramming and promotes survival of reprogrammed neurons when overexpressed

  Xuanyu Chen, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-ELAVL2 (rabbit IgG, 1:100, Santa Cruz), anti-ELAVL2/4 (rabbit IgG ...
• PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination

  Payam Gharibani, et al., bioRxiv - Neuroscience 2023

  Quote: ... or mouse anti-iNOS (1:200, Santa Cruz). After the primary antibodies ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HA (sc-7392, Santa Cruz, mouse, 1:1000); HA (sc-805 ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... (UFD1 (sc-136114, Santa Cruz, mouse, 1:500); UFD1 (611642 ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... HA (sc-805, Santa Cruz, rabbit, 1:1000); HA (MMS-101R ...
• VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

  Ann Schirin Mirsanaye, et al., bioRxiv - Molecular Biology 2023

  Quote: ... NPL4 (sc-365796, Santa Cruz, mouse, 1:500); NPL4 (HPA021560 ...
• BMP7 promotes cardiomyocyte regeneration

  Chiara Bongiovanni, et al., bioRxiv - Molecular Biology 2023

  Quote: ... anti-ERK2 (1:1000, sc-1647, Santa Cruz), anti- phospho-ERK (1:2500 ...
• SOS1 and KSR1 modulate MEK inhibitor responsiveness to target resistant cell populations based on PI3K and KRAS mutation status

  Brianna R. Daley, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-HSP90 (Santa Cruz sc-515081; 1:500), anti-α-tubulin (Abcam ab89984 ...
• The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in colon cancer cells

  Věra Slaninová, et al., bioRxiv - Cancer Biology 2023

  Quote: ... mouse anti-TEAD4 (1/50; Santa Cruz #sc101184), and rabbit anti-YAP (1/100 ...
• Monomeric amyloid-β inhibits microglial inflammatory activity in the brain via an APP/heterotrimeric G protein-mediated pathway

  Hyo Jun Kwon, Devi Santhosh, Zhen Huang, bioRxiv - Neuroscience 2023

  Quote: ... rabbit anti-Cux1 (CDP) (Santa Cruz; 1:100), rabbit anti-laminin (Sigma ...
• Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain

  Alejandro Orrico-Sanchez, et al., bioRxiv - Neuroscience 2023

  Quote: ... antibodies against LAT1 (1/200) from Santa Cruz Biotechnology (CA ...
• Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level

  Birthe Dorgau, et al., bioRxiv - Developmental Biology 2023

  Quote: ... Lumican (1:50, Santa Cruz Biotechnologies, sc-166871), MT2A (1:100 ...
• SOS2 regulates the threshold of mutant EGFR-dependent oncogenesis

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2023

  Quote: ... anti-SOS2 (Santa Cruz sc-258; 1:500), anti-β-actin (Sigma AC-15 ...
• NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma

  Eslam Katab, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GST (1:1,000, mouse, Santa Cruz #sc-138), HA (1:1,000 ...
• NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma

  Eslam Katab, et al., bioRxiv - Cancer Biology 2023

  Quote: ... GAPDH (1:1,000, mouse, Santa Cruz #sc-47724), GST (1:1,000 ...