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3451 - 3500 of 8862 citations for 6 1 4 dioxa 8 azaspiro 4.5 decan 8 yl 3 hydroxy 2 iminopyrimidin 4 amine since 2019

• Time-dependent dual effect of NLRP3 inflammasome in brain ischemia

  Alejandra Palomino-Antolin, et al., bioRxiv - Neuroscience 2020

  Quote: ... or anti-MMP9 (1:1000, Santa Cruz Biotechnology). Appropriate peroxidase-conjugated secondary antibodies (1:5000 ...
• Combining Plasma Extracellular Vesicle Let-7b-5p, miR-184 and Circulating miR-22-3p Levels for NSCLC Diagnosis and for Predicting Drug Resistance

  G. P. Vadla, et al., bioRxiv - Cancer Biology 2021

  Quote: ... mouse anti-mTOR (1:1000, Santa Cruz, #517464) and mouse anti-GAPDH (DSHB ...
• Hepatocyte Cell Cycle Progression Depends on a Transcriptional Repressor Cascade Downstream of Wnt Signaling

  Yinhua Jin, et al., bioRxiv - Cell Biology 2021

  Quote: ... Tbx3 (goat, 1:50, Santa Cruz sc-17871), GS (mouse ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... MyoG (Santa Cruz Biotechnology, sc-12732, 1:100), MYH1 (clone MF20 ...
• Lin28a rejuvenates muscle stem cells via mitochondrial optimization

  Peng Wang, et al., bioRxiv - Cell Biology 2021

  Quote: ... MyoD (Santa Cruz Biotechnology, sc-377460, 1:100), MyoG (Santa Cruz Biotechnology ...
• The role of SOX9 in non-small cell lung cancer progression is histopathology-selective

  Jie Bao, et al., bioRxiv - Cancer Biology 2020

  Quote: ... DaG-HRP (Santa Cruz Biotechnology sc2020, 1:100) was incubated at room temperature for 30 min ...
• Chemical, physical and biological triggers of evolutionary conserved Bcl-xL-mediated apoptosis

  Aleksandr Ianevski, et al., bioRxiv - Cancer Biology 2020

  Quote: ... mouse anti-p53 (1 : 250; Santa Cruz Biotechnology) and anti-Tom40 (1:250 ...
• PDGFR dimer-specific activation, trafficking and downstream signaling dynamics

  Madison A. Rogers, Katherine A. Fantauzzo, bioRxiv - Cell Biology 2021

  Quote: ... PDGFRβ (1:200; 958; sc432; Santa Cruz Biotechnology) (validation ...
• The retromer complex regulates C. elegans development and mammalian ciliogenesis

  Shuwei Xie, et al., bioRxiv - Cell Biology 2021

  Quote: ... and mouse anti-tubulin (1:200) (Santa Cruz Biotechnology ...
• Marked Synergy by Vertical Inhibition of EGFR signaling in NSCLC Spheroids: SOS1 as a therapeutic target in EGFR-mutated cancer

  Patricia L. Theard, et al., bioRxiv - Cancer Biology 2020

  Quote: ... anti-SOS2 (Santa Cruz sc-258; 1:500), anti-β-actin (Sigma AC-15 ...
• SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

  Alison D. Parisian, et al., bioRxiv - Cancer Biology 2020

  Quote: ... SMARCD1 (mouse, 1:1000, Santa Cruz, sc-135843), SMARCC1 (rabbit ...
• SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

  Alison D. Parisian, et al., bioRxiv - Cancer Biology 2020

  Quote: ... BRG1 (mouse, 1:1000, Santa Cruz, sc-17796), Nestin (rabbit ...
• SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability

  Alison D. Parisian, et al., bioRxiv - Cancer Biology 2020

  Quote: ... SMARCC1 (rabbit, 1:1000, Santa Cruz, sc-10756), BRG1 (mouse ...
• Overexpressed Nup88 stabilized through interaction with Nup62 promotes NFκB dependent pathways in cancer

  Usha Singh, Atul Samaiya, Ram Kumar Mishra, bioRxiv - Cancer Biology 2020

  Quote: ... anti-GFP (Santa Cruz# 9996 1:5000 dilutions), anti-GST (1:500 dilution) ...
• Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

  Keerthana Gnanapradeepan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... Tom20 1:100 (F-10, Santa Cruz, sc17764), phospho-Akt (D9E ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... CDK2 (Santa Cruz Biotechnology #sc-6248, 1:200), vinculin (Millipore #05-386 ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... Hsp90 (Santa Cruz Biotechnology #sc-7947, 1:5000).
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... KEAP1 (Santa Cruz Biotechnology #sc-15246, 1:1000), CDK4 (Cell Signaling #12790 ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p38 (Santa Cruz Biotechnology #sc-535, 1:5000), Hsp90 (Santa Cruz Biotechnology #sc-7947 ...
• Sporadic activation of an oxidative stress-dependent NRF2–p53 signaling network in breast epithelial spheroids and premalignancies

  Elizabeth J. Pereira, et al., bioRxiv - Cancer Biology 2019

  Quote: ... p53 (Santa Cruz Biotechnology #sc-126, 1:1000), p21 (Proteintech #10355-1-AP ...
• AMPK promotes Arf6 activation in a kinase-independent manner upon energy deprivation

  Kuan-Jung Chen, Jia-Wei Hsu, Fang-Jen S. Lee, bioRxiv - Cell Biology 2021

  Quote: ... anti-Arf6 (1:1,000, #sc-7971, Santa Cruz), anti-AMPK-P (1:1,000 ...
• ECSIT prevents Alzheimer’s disease pathology by regulating neuronal mitochondrial ROS and mitophagy

  Alice Lepelley, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-TOM6 (1:200; Santa Cruz Biotechnologies), mouse anti-TOM1 (1:100) ...
• Kirrel3-mediated synapse formation is attenuated by disease-associated missense variants

  Matthew R. Taylor, et al., bioRxiv - Neuroscience 2019

  Quote: ... goat-anti-synaptoporin (SPO, 1:1000, Santa Cruz Biotechnology ...
• RanBP2/Nup358 enhances miRNA activity by sumoylating and stabilizing Argonaute 1

  Qingtang Shen, et al., bioRxiv - Molecular Biology 2020

  Quote: ... RanGAP1 (mouse monoclonal, 1:1000 dilution, Santa Cruz), RanBP2 (mouse monoclonal mAb414 1:5000 ...
• Generation of an Unbiased Interactome for the Tetratricopeptide Repeat Domain of O-GlcNAc Transferase Indicates a Role for the Enzyme in Intellectual Disability

  Hannah M. Stephen, et al., bioRxiv - Biochemistry 2020

  Quote: ... anti-OGT (1:1000, Santa Cruz sc-74546), anti-αtubulin (WB 1:5000 ...
• TET1-mediated DNA hydroxy-methylation regulates adult remyelination

  Sarah Moyon, et al., bioRxiv - Neuroscience 2020

  Quote: ... rabbit anti-OLIG2 (Santa Cruz, sc48817, 1:200), mouse anti-SLC12A2 (DSHB,T4 ...
• The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular disease

  Elisa Avolio, et al., bioRxiv - Cell Biology 2021

  Quote: ... anti-PDGFRα (Santa Cruz sc-398206, 1:100). Secondary antibodies conjugated with either Alexa 488 or Alexa 568 or Alexa 647 were purchased from ThermoFisher Scientific and used at a dilution of 1:200 ...
• Intracellular Staphylococcus aureus perturbs the host cell Ca²⁺-homeostasis to promote cell death

  Kathrin Stelzner, et al., bioRxiv - Microbiology 2020

  Quote: ... α-spectrin (1:300, sc-48382, Santa Cruz Biotechnology), β-actin (1:3000 ...
• Origin of diverse phosphorylation patterns in the ERBB system

  T. Okada, et al., bioRxiv - Systems Biology 2020

  Quote: ... 1:500 for ERBB3 (SANTA CRUZ #sc-285), and 1:300 for anti-ERBB4 (SANTA CRUZ #sc-283) ...
• The noncoding RNA PRANCR regulates splicing of Fibronectin-1 to control keratinocyte proliferation and migration

  Auke B.C. Otten, et al., bioRxiv - Cell Biology 2021

  Quote: ... GAPDH (Mouse, 1:200, Santa Cruz Biotechnologies #47724), FN1-total (Mouse ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... -Connexin-43 (1:150; Santa Cruz, sc-271837), -FoxA2 (1:100 ...
• IPSC-derived midbrain astrocytes from Parkinson’s disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

  Peter A. Barbuti, et al., bioRxiv - Neuroscience 2020

  Quote: ... -GI Syn (1:100; Santa Cruz, sc-74430), -GFAP (1:1000 ...
• Single cell transcriptional and functional analysis of human dopamine neurons in 3D fetal ventral midbrain organoid like cultures

  Marcella Birtele, et al., bioRxiv - Neuroscience 2020

  Quote: ... goat anti-neurogenin2 (Ngn2, 1:500, Santa Cruz), mouse anti-microtubule-associated protein 2 (Map2 ...
• GSAP Regulates Amyloid Beta Production through Modulation of Amyloid Precursor Protein Trafficking

  Jerry C. Chang, et al., bioRxiv - Neuroscience 2020

  Quote: ... GAPDH antibody (1:500, sc-365062, Santa Cruz), β-tubulin antibody (1:2000 ...
• Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting

  Gianmatteo Vit, et al., bioRxiv - Cell Biology 2021

  Quote: ... (#sc-47778 HRP, 1:5000, Santa Cruz Biotechnology), TRAPPC2L (#HPA041714 ...
• Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson’s disease

  Subhrangshu Guhathakurta, et al., bioRxiv - Neuroscience 2020

  Quote: ... and TH (Santa Cruz, SC-25269; 1:200) antibodies were used.
• Loss of the Er81 Transcription Factor in Cholinergic Cells Alters Striatal Activity and Habit Formation

  Yadollah Ranjbar-Slamloo, et al., bioRxiv - Neuroscience 2020

  Quote: ... mouse anti-c-Fos (1:500; Santa Cruz) or rabbit anti-p-Ser240–244-S6rp (1:500 ...
• MEKK3-TGFβ crosstalk regulates inward arterial remodeling

  Hanqiang Deng, et al., bioRxiv - Pathology 2021

  Quote: ... TGFβR2 (Santa Cruz sc-400; IB 1:1000), TGFβ (R&D Systems MAB1835 ...
• Ran-GTP is non-essential to activate NuMA for spindle pole focusing, but dynamically polarizes HURP to control mitotic spindle length

  Kenta Tsuchiya, et al., bioRxiv - Cell Biology 2020

  Quote: ... RanGAP1 (Santa Cruz Biotechnology, H-180, 1:200), importin-β (GeneTex ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-PP1γ 1:1000 (Santa Cruz, sc-6108), anti-pUL34 1:500 (Gao et al. ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-PP1β 1:1000 (Santa Cruz, sc-373782), anti-PP1γ 1:1000 (Santa Cruz ...
• pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread

  Tomasz H. Benedyk, et al., bioRxiv - Microbiology 2021

  Quote: ... anti-PP1α 1:1000 (Santa Cruz, sc-271762), anti-PP1β 1:1000 (Santa Cruz ...
• ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression

  Xianjiang Lan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... γ-globin (1:1000, Santa Cruz, Cat. #sc-21756), β-actin (1:1000 ...
• ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression

  Xianjiang Lan, et al., bioRxiv - Molecular Biology 2020

  Quote: ... GATA1 (1:1000, Santa Cruz, Cat. #sc-265), γ-globin (1:1000 ...
• Fatal COVID-19 and non-COVID-19 Acute Respiratory Distress Syndrome is Associated with Incomplete Alveolar Type 1 Epithelial Cell Differentiation from the Transitional State Without Fibrosis

  Christopher Ting, et al., bioRxiv - Pathology 2021

  Quote: ... CCSP (Santa Cruz Biotechnology sc-365992, 1:100), and/or SARS nucleocapsid protein (Novus NB100-56576 ...
• Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes

  Shuxin Liu, et al., bioRxiv - Microbiology 2020

  Quote: ... α-HA (Santa Cruz, cat# sc-7392, 1: 1000), α-ICDH (1 ...
• Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration

  Abigail H. Cleveland, et al., bioRxiv - Neuroscience 2021

  Quote: ... SOX10 diluted 1:100 (Santa Cruz, #sc-17342), cleaved-Caspase 3 (cC3 ...
• Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer

  Suzann Duan, et al., bioRxiv - Cancer Biology 2020

  Quote: ... eNOS (1:100, Santa Cruz Biotechnology, Dallas, TX), iNOS (1:50 ...
• Cavin3 released from caveolae interacts with BRCA1 to regulate the cellular stress response

  Kerrie-Ann McMahon, et al., bioRxiv - Cancer Biology 2020

  Quote: ... and rabbit polyclonal BRCA1 (1:200, Santa Cruz), cavin3 (1:150 ...
• Platelet TSP-1 Controls Prostate Cancer-Induced Osteoclast Differentiation and Bone Marrow-Derived Cell Mobilization through TGFβ-1

  Bethany A. Kerr, et al., bioRxiv - Cancer Biology 2020

  Quote: ... TSP-1 antibody (Santa Cruz Biotechnology; RRID: AB_831756) was used to detect platelet-derived proteins ...