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• Low concentrations of ethylene bisdithiocarbamate pesticides maneb and mancozeb impair manganese and zinc homeostasis to induce oxidative stress and caspase-dependent apoptosis in human hepatocytes

  Kilian Petitjean, et al., bioRxiv - Pharmacology and Toxicology 2023

  Quote: ... anti-phospho Ser52-eIF2a (sc-12412, Santa Cruz) and HSC70 (B-6 ...
• Changes in cell morphology and function induced by NRAS Q61R mutation in lymphatic endothelial cells

  Shiho Yasue, et al., bioRxiv - Cell Biology 2023

  Quote: ... Protein expression was normalized to GAPDH (sc-2577; Santa Cruz Biotechnology, Santa Cruz, CA, USA)
• The CB₁ receptor interacts with cereblon and drives cereblon deficiency-associated memory shortfalls

  Carlos Costas-Insua, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse monoclonal anti-Gαq/11 (1:20, Santa Cruz Biotechnology #sc-515689), rabbit polyclonal anti-Gαs (1:20 ...
• Anti-apoptotic and anti-inflammatory properties of grapefruit IntegroPectin on human microglial HMC3 cell line

  Miriana Scordino, et al., bioRxiv - Neuroscience 2023

  Quote: ... mouse p-NF-kB (1:500, sc-136548 Santa Cruz Biotechnology). The day after ...
• Biochemical and chemical biological approaches to mammalian sleep: roles of calcineurin in site-specific dephosphorylation and sleep regulation

  Jianjun Yu, et al., bioRxiv - Neuroscience 2023

  Quote: ... anti-SIK3 (Santa Cruz, sc-515408), anti-SIK3 pT221 (Abcam ...
• Epigenomic Analyses Identify FOXM1 As a Key Regulator of Anti-Tumor Immune Response in Esophageal Adenocarcinoma

  Benjamin Ziman, et al., bioRxiv - Cancer Biology 2023

  Quote: Cells were lysed using the RIPA lysis buffer system (Santa Cruz Biotechnologies, sc-24948A), supplemented with proteinase inhibitor cocktail and PMSF for 30 min on ice ...
• Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targeting of WRN and ATR

  Dali Zong, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Cyclin A (1:200, Santa Cruz) and/or RPA2 (1:2,000 ...
• MEK inhibition enhances the antitumor effect of radiation therapy in NF1-deficient glioblastoma

  Maria Ioannou, et al., bioRxiv - Cancer Biology 2023

  Quote: ... MGMT (sc-166528) was obtained from Santa Cruz Biotechnology.
• XRN1 deletion induces PKR-dependent cell lethality in interferon-activated cancer cells

  Tao Zou, et al., bioRxiv - Cancer Biology 2023

  Quote: ... Lentivirus was harvested at 48 and 72 hours after transfection in RPMI media supplemented with 10% FBS and filtered with 45 μm filters prior to transduction of cancer cell lines using centrifugation at 1000 g for 2 hours in the presence of 8 μg/mL of polybrene (Santa Cruz Biotechnology). Transduced cell lines were selected in puromycin and/or blasticidin (Thermo Fisher Scientific ...
• FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancer

  Nicla Lorito, et al., bioRxiv - Cancer Biology 2023

  Quote: ... SCD2 (Santa Cruz Biotechnology, #sc-518034) ACSL4 (Santa Cruz Biotechnology ...
• FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancer

  Nicla Lorito, et al., bioRxiv - Cancer Biology 2023

  Quote: ... SCD1 (Santa Cruz Biotechnology, #sc-515844), SCD2 (Santa Cruz Biotechnology ...
• FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancer

  Nicla Lorito, et al., bioRxiv - Cancer Biology 2023

  Quote: ... The following antibodies were used: ACLY (Santa Cruz Biotechnology #sc-517267), FASN (Santa Cruz Biotechnology ...
• FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancer

  Nicla Lorito, et al., bioRxiv - Cancer Biology 2023

  Quote: ... ACSL4 (Santa Cruz Biotechnology, #sc-365230), HSP90 (Santa Cruz Biotechnology #sc-69703) ...
• TRIB1 modulates transcriptional programming in breast cancer cells to regulate cell proliferation

  Hamish D. McMillan, et al., bioRxiv - Cancer Biology 2023

  Quote: ... media was removed and cells incubated with 20 mL of PBS containing 2 mM disuccinimidyl glutarate (DSG) (Santa Cruz Chemical) for 20 minutes at room temperature ...
• Somatic mutation of Afadin leads to anchorage independent survival and metastatic growth of breast cancer through αE-catenin dependent destabilization of the adherens junction

  Max A.K. Ratze, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and GFP (SC-8334;1:150; Santa Cruz). Endogenous peroxidases were blocked with 3% H2O2and biotin-conjugated secondary antibodies were used ...
• Establishment of a novel non-integrated human pluripotent stem cell-based gastruloid model

  Gege Yuan, et al., bioRxiv - Developmental Biology 2023

  Quote: The primary antibodies included: mouse anti-OCT4 antibody (Santa Cruz Biotechnology, Sc-5279; 1:100), rabbit anti-OCT4 antibody (Abcam ...
• NOTCH3 signalling controls human trophoblast stem cell expansion and differentiation

  Bianca Dietrich, et al., bioRxiv - Developmental Biology 2023

  Quote: ... and 5µM Y27632 (Santa Cruz). Cells were passaged with 80-90% confluence at a split ratio of 1:2-1:4 using TrypLE (Gibco ...
• Modeling wild type and mutant p53 in telomerase-immortalized human cells

  Jessica J. Miciak, Fred Bunz, bioRxiv - Cancer Biology 2023

  Quote: ... Antibodies for the detection of p53 (DO-1) and MDM2 (SMP14) were obtained from Santa Cruz Biotechnology ...
• Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma

  Sophia M Lauer, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and GFP were purchased from Santa Cruz Biotechnology ...
• Synergistic effects of PARP inhibitors by Schlafen 11 and BRCA2-deficiency through accumulation of single-strand DNA gaps behind a fork

  Hiroshi Onji, et al., bioRxiv - Cancer Biology 2023

  Quote: ... were obtained from Santa Cruz Biotechnology (Santa Cruz, CA, USA); antibodies against BRCA2 (cat ...
• Reprogramming of breast tumor-associated macrophages with modulation of arginine metabolism

  Veani Fernando, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and S-Nitrosoglutathione (GSNO, 100 or 200μM, Santa Cruz Bio, Dallas, TX, Cat. No. sc-200349B), or SEP ...
• A highly efficient human cell-free translation system

  Nikolay A. Aleksashin, et al., bioRxiv - Biochemistry 2023

  Quote: ... Anti-mouse IgG-HRP (sc-525409) and GADD34 (sc-373815) were from Santa Cruz Biotechnology ...
• Medulloblastoma-associated DDX3X mutants are oncogenic having a defect in translation-promoting activity but functional in stress granule formation and interferon signaling

  Satishkumar Vishram Singh, et al., bioRxiv - Cancer Biology 2023

  Quote: Anti-eIF4G (sc-11373, Santa Cruz Biotechnology, TX, USA); anti-FLAG® M2 antibody (Sigma-Aldrich ...
• Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity

  Melica Nourmoussavi Brodeur, et al., bioRxiv - Cancer Biology 2023

  Quote: ... and vinculin (sc-73614, Santa Cruz; 1:5000) were used as reference protein ...
• Characterization and super-resolution imaging of small tau aggregates in human samples

  Dorothea Böken, et al., bioRxiv - Biochemistry 2023

  Quote: ... T181 (abcam, Cat. No. ab232849 and SC211 (Santa Cruz, Cat. No. sc-12767L) were biotinylated site-specifically through Click chemistry ...
• Autophagy maintains the homeostatic environment in the male reproductive accessory organs playing a key role in fertility

  Adil Jaulim, et al., bioRxiv - Cell Biology 2023

  Quote: ... or Tris-EDTA buffer (10mM Tris Base, 1mM EDTA Solution, 0.05% Tween 20, pH 9) for AR (Santa Cruz, sc-816, 1:500) and tGFP (Thermo Fisher ...
• Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) LANA Prevents KSHV Episomes from Degradation

  Ken-ichi Nakajima, et al., bioRxiv - Microbiology 2023

  Quote: ... Anti-K8α mouse monoclonal and anti-ORF57 mouse monoclonal antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). Anti-cGAS rabbit monoclonal antibody was purchased from Cell Signaling Technology (Danvers ...
• Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) LANA Prevents KSHV Episomes from Degradation

  Ken-ichi Nakajima, et al., bioRxiv - Microbiology 2023

  Quote: ... Anti-K8α mouse monoclonal and anti-ORF57 mouse monoclonal antibodies were purchased from Santa Cruz Biotechnology (Santa Cruz ...
• Ikzf1 association with Foxp3 for Foxp3-dependent gene repression in Treg cells: induction of autoimmunity and tumor immunity by disrupting the association

  Kenji Ichiyama, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Ikzf3 (Santa Cruz Biotechnology), anti-CHD4 (Sigma-Aldrich) ...
• A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages

  Izumi Sasaki, et al., bioRxiv - Immunology 2023

  Quote: ... anti-Caspase-1 p10 (sc-514; 1/1000 dilution, Santa Cruz Biotechnology), anti-GSDMD (ab209845 ...
• A stress sensor IRE1α is required for bacterial exotoxin-induced inflammasome activation in tissue-resident macrophages

  Izumi Sasaki, et al., bioRxiv - Immunology 2023

  Quote: The following antibodies (Abs) were used: anti-β-actin Ab (C4) (sc-47778; 1/1000 dilution, Santa Cruz Biotechnology), anti-IRE1α (3294 ...
• ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons

  Jacob A. Klickstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... GAPDH (sc-47724 Santa Cruz), NESTIN (NBP1-92717SS Novus Biologicals) ...
• ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons

  Jacob A. Klickstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... TOMM20 (sc-17764 Santa Cruz), TOMM70 (sc-390545 Santa Cruz) ...
• ALS-related p97 R155H mutation disrupts lysophagy in iPSC-derived motor neurons

  Jacob A. Klickstein, et al., bioRxiv - Neuroscience 2023

  Quote: ... Retinoic acid (sc-200898) was obtained from Santa Cruz. Compound E (565790 ...
• OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis

  Eugénie Goupil, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse α-6xHis (clone H3, 1:1000, Santa Cruz, sc-8036). The following secondary antibodies were used ...
• Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

  Yuqi Gui, et al., bioRxiv - Neuroscience 2023

  Quote: ... The primary antibodies used here were: goat against MAP2 (S-15; 1:100; Santa Cruz #sc-12012) and rabbit against Synapsin1 (1:500 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti CD63 (dilution 1/500; Santa Cruz Biotechnology; H-193), anti-TSG101 (dilution 1/200 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-CD81 (dilution 1/500; Santa Cruz Biotechnology; B-11) and anti-CD9 (dilution 1/500 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-CD9 (dilution 1/500; Santa Cruz Biotechnology; C-4). Secondary antibodies were anti-IgG rabbit (dilution 1/4000 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... anti-TSG101 (dilution 1/200; Santa Cruz Biotechnology; C-2), anti-CD81 (dilution 1/500 ...
• Identification of omega-3 oxylipins in human milk-derived extracellular vesicles with pro-resolutive actions in gastrointestinal inflammation

  Marta Gómez-Ferrer, et al., bioRxiv - Cell Biology 2023

  Quote: ... Human primary antibodies used for western blotting (WB) were as follows: anti-calnexin (dilution 1/1000, Santa Cruz Biotechnology, H-70), anti-Hsp70 (dilution 1/500 ...
• Functional interaction of torsinA and its activators in liver lipid metabolism

  Antonio Hernandez-Ono, et al., bioRxiv - Cell Biology 2023

  Quote: ... β-actin (Santa Cruz Biotechnology, sc-47778), myosin heavy chain (Santa Cruz Biotechnology ...
• Mitochondrial Ca²⁺ uniporter (MCU) variants form plasma-membrane channels

  Iuliia Polina, et al., bioRxiv - Cell Biology 2023

  Quote: All the protein samples were separated by sodium dodecyl sulfate polyacrylamide (SDS)-PAGE and were transferred to nitrocellulose membrane (Bio-Rad laboratories, Genesee Scientific, Cytiva, and Santa Cruz Biotechnology) and incubated with primary antibodies ...
• Downregulation of a cell polarity protein potentiates Chikungunya Virus infection in host cells

  Ramesh Kumar, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by SDS-PAGE and Western blotting with a primary antibody against Scribble (1:500, Santa Cruz sc55543), beta-actin (1:1000 ...
• Downregulation of a cell polarity protein potentiates Chikungunya Virus infection in host cells

  Ramesh Kumar, et al., bioRxiv - Cell Biology 2023

  Quote: ... followed by incubation with protein A/G agarose beads (Santa Cruz sc-2003) for 1 hour at 4 °C with gentle mixing ...
• A Medium Chain Fatty Acid, 6-hydroxyhexanoic acid (6-HHA), Protects Against Obesity and Insulin Resistance

  Sara C. Sebag, et al., bioRxiv - Physiology 2023

  Quote: ... anti-AKT1 (H-136, Santa Cruz, sc-8312) or anti-ACTB (H-300 ...
• UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope

  Yongrong Liao, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-TIA-1 (Santa Cruz Biotechnology, sc-166247), mouse monoclonal anti-FXR1 (Millipore ...
• UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope

  Yongrong Liao, et al., bioRxiv - Cell Biology 2023

  Quote: ... mouse monoclonal anti-Cyclin E (HE12) (Santa Cruz Biotechnology, sc-247), mouse monoclonal anti-Nup133 (E-6 ...
• pADP-ribosylation Regulates the Cytoplasmic Localization, Cleavage and Pro-apoptotic Function of HuR

  Kholoud Ashour, et al., bioRxiv - Cell Biology 2023

  Quote: ... and anti-PP32/PHAPI (Santa Cruz) were incubated with 60 µl of protein A-Sepharose slurry beads (GE Healthcare ...
• Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

  Jayne Aiken, Erika L. F. Holzbaur, bioRxiv - Cell Biology 2023

  Quote: ... Neurons were incubated with primary antibodies against spastin 3G11/1 (anti-mouse; Santa Cruz Biotechnology; sc-53443 1:250 dilution), EB3 (anti-rat ...